1)calcium levofolinate左亚叶酸钙
1.A HPLC method was established for the determination of calcium levofolinate and its tablets as well as the related substances.建立了HPLC法测定左亚叶酸钙及其片剂含量与有关物质。
英文短句/例句
1.Randomized, Control Study of Calcium Levofolinate or Calcium Folinate Plus 5-fluorouracil and Oxaliplatin in Metastatic Colorectal Cancer;左亚叶酸钙或亚叶酸钙联合5-氟尿嘧啶和奥沙利铂治疗转移性大肠癌的临床研究
2.Determination of calcium levofolinate in urine by flow injection chemiluminescence method流动注射化学发光法快速测定尿液中左亚叶酸钙
3.The clinical research for calcium levofolinate with 5-fluorouracil for the treatment of advanced gastric cancer and colorectal cancer注射用左亚叶酸钙联合治疗晚期胃癌和结直肠癌的Ⅱ期临床研究
4.calcium folinate (INN)亚叶酸钙(国际非专利药品名称)
5.Pharmacokinetics and Bioequivalence of Calcium Folinate Dispersed Tablets亚叶酸钙分散片人体药动学与生物等效性研究
6.Docetaxel Combined with Oxaplatin and Calcium Folinate,5-Fluorouracil in the Treatment of the Advanced Gastric Carcinoma多西他赛联合草酸铂及亚叶酸钙,5-氟脲嘧啶治疗晚期胃癌
7.Clinical research about the effect of different administration method of calcium Folinate to anti gastrointestinal(GI)reaction induced by methotrexate(MTX),亚叶酸钙不同给药途径拮抗氨甲喋呤胃肠道反应的临床研究
8.Phase Ⅱ Trial of Lobaplatin, Leucovorin and Fluorouracil in Patient with Advanced Carcinoma of the Esophagus;洛铂联合5-FU、亚叶酸钙治疗晚期食管癌的Ⅱ期临床研究
9.Clinical Analysis of Oxaliplatin Combined with 5-Fluorouracil and Calcium Folinate in Treatment of Colorectal Cancer;奥沙利铂联合5-氟尿嘧啶与亚叶酸钙治疗结直肠癌的临床分析
10.Clinical Observation of Oxaliplatin (L-OHP) Combined with 5-fluorouracil(5-FU)/leucovorin(CF) in the Treatment of Old Advanced Gastric Cancer;奥沙利铂联合氟尿嘧啶/亚叶酸钙治疗老年晚期胃癌的临床观察
11.Observation of effects of oxliplatin combined with fluorouracil and calcium folinate on advanced colorectal cancer国产奥沙利铂联合氟尿嘧啶/亚叶酸钙治疗晚期结肠癌的疗效观察
12.Oxaliplatin combined with leucovorin and 5-fluorouracil chemotherapy in treatment of advanced gastric cancer奥沙利铂联合亚叶酸钙/氟尿嘧啶治疗晚期胃癌的临床观察
13.Clinical study of combined oxaliplatin with fluorouracil and calcium folimate in the treatment of advanced gastric cancer奥沙利铂联合氟尿嘧啶、亚叶酸钙治疗晚期胃癌的临床观察
14.The clinical observation of oxaliplatin and 5-FU combined with CF in patients with advanced colorectal cancer奥沙利铂与氟尿嘧啶 亚叶酸钙联合治疗晚期大肠癌的临床观察
15.Regulation effect of calcium and salicylic acid on defense enzyme activities in tomato leaves under sub-high temperature stress钙和水杨酸对亚高温胁迫下番茄叶片保护酶活性的调控作用
16.Effects of combinaed chemtherapy with oxaliplatin and leucovorin/5-fluorouracil for advanced gastric cardial carcinoma奥沙利铂联合亚叶酸钙及氟尿嘧啶治疗晚期贲门癌46例疗效观察
17.The Effect of Paclitaxel Combined with 5-fluorouracil and Calcium Folinate on Advanced Gastric Cancer紫杉醇联合5-氟脲嘧啶、亚叶酸钙治疗晚期胃癌的疗效
18.Study on Co-precipitation Experiment of Calcium Sulfite and Calcium Sulfate亚硫酸钙和硫酸钙混合物共沉淀实验研究
相关短句/例句
calcium levofolinate for injection注射用左亚叶酸钙
1.Pharmacokinetics of calcium levofolinate for injection in healthy volunteers;注射用左亚叶酸钙的人体药动学
3)Calcium Folinate亚叶酸钙
1.Study on the Charge-Transfer Reaction of Calcium Folinate with p-Nitrophenol;亚叶酸钙与对硝基酚荷移反应的研究
2.Clinical study of combined oxaliplatin with 5-fluorouracil and calcium folinate in advanced gastric cancer;奥沙利铂联合氟尿嘧啶及亚叶酸钙治疗晚期胃癌的疗效观察
3.The efficacy and safety of oxaliplatin combined with calcium folinate and fluorouracil in the treatment of old patients with advanced colon cancer;奥沙利铂联合亚叶酸钙和氟尿嘧啶治疗高龄晚期结肠癌的疗效和安全性
4)Leucovorin[,lju:k?'v?rin]亚叶酸钙
1.Clinical observation of oxaliplatin plus 5-fluorouracil leucovorin in treatment of advanced gastrointestinal carcinoma;联合运用奥沙利铂、5-氟尿嘧啶、亚叶酸钙治疗中晚期胃肠道肿瘤的临床观察
2.Clinical Study of 34 Cases on the Treatment of Advanced Colorectal Carcinoma with Oxaliplatin in Combination 5-Flouruorail Continuous Infusion(Biweek Schedule) and Leucovorin;奥沙利铂联合5-氟脲嘧啶持续静脉滴注48h及亚叶酸钙(双周疗法)治疗晚期大肠癌34例的临床观察
3.Oxaliplatin in Combination with 5-fluorouracil and Leucovorin for Treating Advanced Gastric Cancer;奥沙利铂联合5-氟尿嘧啶和亚叶酸钙治疗晚期胃癌36例
5)CF亚叶酸钙
1.Oxaliplatin combined with 5-FU/CF for the treatment of patients with advanced gastric carcinoma;奥沙利铂联合氟尿嘧啶亚叶酸钙治疗晚期胃癌
2.Oxaliplatin and 5 - FU Combined with CF in Patients with Advanced Colorectal Cancer;奥沙利铂联合氟尿嘧啶和亚叶酸钙治疗晚期大肠癌
3.Objective To observe the clinical efficacy of OLF (oxaliplatin plus CF and 5-Fu) regimen and LFP (DDP plus CF and 5-Fu) regimen in treatment of the patients with advanced gastric carcinoma.其中OLF组(草酸铂、亚叶酸钙、5-Fu)26例,LFP组(顺铂、亚叶酸钙、5-Fu)22例,对比观察两种方案的疗效和毒性。
6)calcium folinate tablet亚叶酸钙片
1.Relative bioavailability of calcium folinate tablets in healthy volunteers;亚叶酸钙片的人体相对生物利用度
延伸阅读
亚叶酸钙片药物名称:亚叶酸钙片英文名:Calcium Folinate Tablets汉语拼音:主要成分:本品主要成分是亚叶酸钙性状:本品为类白色或淡黄色片。药理作用:本品为四氢叶酸的甲酰衍生物,主要用于高剂量甲氨喋呤等叶酸拮抗剂的解救。 甲氨喋呤的主要作用是与二氢叶酸还原酶结合,阻断二氢叶酸转变为四氢叶酸从而抑制DNA的合成。本品进入体内后,通过四氢叶酸还原酶转变为四氢叶酸,纯有效地对抗甲氨喋呤引起的毒性反应,但对已存在的甲氨喋呤神经毒性则无明显作用。药代动力学:本品口服后易于吸收,1.72±0.8小时后,血清还原叶酸达峰值,药物作用持续3~6小时;经肝和肠粘膜作用后本品代谢为5-甲基四氢叶酸,口服后代谢较肌注快而充分,80~90%经肾排出,小量随粪便排泄。适应症:1.用作叶酸拮抗剂(如甲氨喋呤、乙胺嘧啶或甲氧苄啶等)的解毒剂。 2.用于预防甲氨喋呤过量或大剂量治疗后所引起的严重毒性作用。 3.由叶酸缺乏所引起的巨幼细胞性贫血。 4.与5-氟尿嘧啶合用,用于治疗晚期结肠癌,直肠癌。用法与用量:1.本品口服,作为甲氨蝶呤的“解救”疗法,剂量最好根据血药浓度测定结果。一般采用的剂量为5~15mg,每6~8小时一次,连续2日。 2.作为乙胺嘧啶或甲氧苄啶等的解毒剂,每日剂量5~15mg,视中毒情况而定。 3.用于贫血,每日口服15mg。 4.与5-氟尿嘧啶合用时,口服20~30mg/m2体表面积,在5-Fu用药前半小时口服。不良反应:很少见,偶见皮疹、荨麻疹或哮喘等过敏反应。禁忌症:禁用于恶性贫血或维生素B12缺乏所引起的巨幼细胞性贫血。注意事项:1.初次使用本品,应在有经验医师指导下用药。 2.本品不应与叶酸拮抗剂(如:甲氨喋呤)同时使用,以免影响后者的治疗作用。 3.当患者有下列情况者,本品应慎用于甲氨蝶呤的“解救”治疗:酸性尿(pH<7)、腹水、脱水、肠梗阻、胸腔积液或肾功能障碍。有上述情况时,甲氨蝶呤毒性较显著,且不易从体内排出:病情急需者,本品剂量有加大。 4.接受大剂量甲氨蝶呤后而用本品“解救”者应进行下列各种实验室监测:(1)治疗前测肌酐清除率;(2)应用甲氨蝶呤后每12~24小时测定血浆或血清甲氨蝶呤浓度,以调整本品剂量,当甲氨蝶呤浓度低于5×108mol/L时,可以停止实验室监测;(3)应用甲氨蝶呤治疗前及以后每24小时应测定血清肌酐量,如用药后24小时血清肌酐大于治疗前50%,提示产生严重肾毒性,要慎重处理;(4)甲氨蝶呤用药前及用药后每6小时应监测尿液酸酸度,要求尿液pH值在7以上,必要时用碳酸氢钠和水化治疗(每日补液量在300ml/m2体表面积);(5)本品不应与甲氨蝶呤同时应用,以免影响后者抗叶酸作用,应一次给予大剂量甲氨蝶呤后24~48小时再应用本品,并且对给药剂量有特殊要求,即要求给药后期血浆浓度等于或大于甲氨蝶呤浓度。 5.本品较大剂量与巴比妥、扑米酮或苯妥英钠同用,可影响抗癫痫作用。 6.本品应避免光线直接照射及热接触。过期药物不得应用。规格:15mg(以亚叶酸计)。贮藏:密闭、在凉暗干燥处保存。有效期:暂定二年。处方药:
