除草组合物的制作方法

专利名称：除草组合物的制作方法
技术领域：
本发明涉及新的除草组合物，其中包含适于选择性地控制有用植物农作物例如玉米农作物中的杂草的除草活性组分组合。本发明还涉及控制有用植物农作物中的杂草的方法，以及新的组合物在这样的用途中的应用。式I化合物 其中取代基的定义在下文中给出，具有除草活性。
令人惊奇的是，现在已经发现，不定量的活性组分、即不定量的式I活性组分与一种或多种下文所列出的已知的、并且某些可商购获得的式2.1-2.51活性组分的组合表现出协同作用，能够控制尤其是在有用植物农作物中生长的大多数杂草(既能控制芽前的杂草，也能控制苗后的杂草)。
因此，本发明提供了用于选择性地控制杂草的新的协同组合物，所述组合物除了含有常规惰性制剂助剂以外，还含有下列组分的混合物作为活性组分a)除草有效量的式I化合物或其农业可接受盐 其中每个R独立地为氢、C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基、C1-C6卤代烷硫基、C1-C6卤代烷基亚磺酰基、C1-C6卤代烷基磺酰基、C1-C6烷氧基羰基、C1-C6烷基羰基、C1-C6烷基氨基、二(C1-C6烷基)氨基、C1-C6烷基氨基磺酰基、二(C1-C6烷基)氨基磺酰基、-N(R1)-S-R2、-N(R3)-SO-R4、-N(R5)-SO2-R6、硝基、氰基、卤素、羟基、氨基、苄硫基、苄基亚磺酰基、苄基磺酰基、苯基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基；其中所述苯基自身可被下列基团单取代、二取代或三取代C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R45、NR46R47、卤素、氰基、硝基、苯基或苄硫基，其中后面所述的苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；或者每个R独立地为5-10元单环或稠合二环系，所述环系可以是芳环或部分饱和环，并且可以含有1-4个选自氮、氧和硫的杂原子；其中所述环系直接与吡啶环连接，或者经由C1-C4亚烷基与吡啶环连接，并且每个环系不可以含有2个以上的氧原子，不可以含有2个以上的硫原子，所述环系自身可被下列基团单取代、二取代或三取代C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R7、NR8R9、卤素、氰基、硝基、苯基或苄硫基，其中所述苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代，并且在杂环中的氮上的取代基不是卤素；或者每个R独立地为C1-C4烷氧基-C1-C4烷基或C1-C4烷氧基-C1-C4烷氧基-C1-C4烷基；m是1、2、3或4；R1、R3和R5分别独立地为氢或C1-C6烷基；R2是NR10R11、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；R4是NR12R13、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；R6是NR14R15、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；R7和R45分别独立地为C1-C3烷氧基、C2-C4烷氧基羰基、C1-C3烷硫基、C1-C3烷基亚磺酰基、C1-C3烷基磺酰基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；R8、R10、R12、R14和R46分别独立地为氢或C1-C6烷基；R9、R11、R13、R15和R47分别独立地为C1-C6烷基或C1-C6烷氧基；Q是基团Q1 其中R16、R17、R18和R19分别独立地为氢、羟基、C1-C4烷基、C2-C6链烯基、C2-C6炔基、C1-C4烷氧基羰基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-NHS(O)2、C1-C4卤代烷基、-NH-C1-C4烷基、-N(C1-C4烷基)2、C1-C6烷氧基、氰基、硝基、卤素、或苯基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者R16、R17、R18和R19当中的两个相邻取代基形成C2-C6亚烷基桥；R20是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R21R22N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；且R21和R22分别独立地为氢或C1-C4烷基；或者是基团Q2 其中R23是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4-链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R24R25N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；R24和R25分别独立地为氢或C1-C4烷基；且Y是氧、硫、化学键或C1-C4亚烷基桥；或者是Q3 其中R44、R37、R38和R39分别独立地为氢、C1-C6烷基、C1-C6卤代烷基、C2-C6链烯基、C2-C6炔基、C1-C6烷氧基羰基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6烷基-NHS(O)2、C1-C6烷基氨基、二(C1-C6烷基)氨基、羟基、C1-C6烷氧基、C3-C6链烯氧基、C3-C6炔氧基、羟基-C1-C6烷基、C1-C4烷基-磺酰基氧基-C1-C6烷基、甲苯磺酰基氧基-C1-C6烷基、卤素、氰基、硝基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-S(O)2O、C1-C6卤代烷硫基、C1-C6卤代烷基亚磺酰基、C1-C6卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C6烷硫基-N(C1-C4烷基)、C1-C6烷基亚磺酰基-N(C1-C4烷基)、C1-C6烷基磺酰基-N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者相邻的R44和R37或R38和R39一起为C3-C6亚烷基；W是氧、硫、亚磺酰基、磺酰基、-CR41R42-、-C(O)-或-NR43-；R41是氢、C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基-C1-C4烷基、C1-C4烷硫基-C1-C4烷基、C1-C4烷基羰基氧基-C1-C4烷基、C1-C4烷基磺酰基氧基-C1-C4烷基、甲苯磺酰基氧基-C1-C4烷基、二(C1-C3烷氧基烷基)甲基、二(C1-C3烷硫基烷基)甲基、(C1-C3烷氧基烷基)-(C1-C3烷硫基烷基)甲基、C3-C5氧杂环烷基、C3-C5硫杂环烷基、C3-C4二氧杂环烷基、C3-C4二硫杂环烷基、C3-C4氧杂硫杂环烷基、甲酰基、C1-C4烷氧基羰基、或苯基，所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C6烷硫基-N(C1-C4烷基)、C1-C6烷基亚磺酰基-N(C1-C4烷基)、C1-C6烷基磺酰基-N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者R42与R39一起为C1-C6亚烷基；R42是氢、C1-C4烷基或C1-C4卤代烷基；R40是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R96R97N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；R96和R97分别独立地为氢或C1-C4烷基；R43是氢、C1-C4烷基、C1-C4烷氧基羰基、或苯基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；或者是基团Q4 其中R30是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R31R32N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；且R31和R32分别独立地为氢或C1-C4烷基；R33和R34分别独立地为氢、羟基、C1-C4烷基、C2-C6链烯基、C2-C6炔基、C1-C4烷氧基羰基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-NHS(O)2、C1-C4卤代烷基、-NH-C1-C4烷基、-N(C1-C4烷基)2、C1-C6烷氧基、氰基、硝基、卤素、或苯基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4-烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者R33和R34一起形成C2-C6亚烷基桥；且R35是氢、C1-C4烷基、C1-C4烷氧基羰基、或苯基，所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者是基团Q5 其中Z是硫、SO或SO2；R01是氢、C1-C8烷基、被下列基团取代的C1-C8烷基卤素、C1-C4烷氧基、C1-C4烷硫基、C1-C4烷基磺酰基、C1-C4烷基亚磺酰基、羟基、氰基、硝基、-CHO、-CO2R02、-COR03、-COSR04、-NR05R06、CONR036R037、或苯基，所述苯基自身可被下列基团取代C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7-环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR025R026、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR015CO2R027；或者R01是C2-C8链烯基或被下列基团取代的C2-C8链烯基卤素、C1-C4烷氧基、C1-C4烷硫基、C1-C4烷基磺酰基、C1-C4烷基亚磺酰基、-CONR032R033、氰基、硝基、-CHO、-CO2R038、-COR039、-COS-C1-C4烷基、-NR034R035、或苯基，所述苯基自身可被下列基团取代C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR040R041、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR043CO2R042；或者R01是C3-C6炔基或被下列基团取代的C3-C6炔基卤素、C1-C4卤代烷基、氰基、-CO2R044、或苯基，所述苯基自身可被下列基团取代C1-C4烷基、C1-C6卤代烷基、C1-C4-烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4-烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR028R029、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR031CO2R030；或者R01是C3-C7环烷基或被下列基团取代的C3-C7环烷基C1-C4烷基、C1-C4烷氧基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、或苯基，所述苯基自身可被下列基团取代卤素、硝基、氰基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷硫基、C1-C4卤代烷硫基、C1-C4烷基或C1-C4卤代烷基；或者R01是C1-C4亚烷基-C3-C7环烷基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4-烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR045R046、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基或-NR048CO2R047；或者R01是C1-C4亚烷基苯基、COR07或4-6元杂环基；R02、R038、R044和R066分别独立地为氢、C1-C4烷基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)-SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR049R050、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、-C1-C4-烷基苯基或-NR052CO2R053；R03、R039和R067分别独立地为C1-C4烷基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)-SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR068R054、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、-(CH2)t-苯基或-NR056CO2R055；R04是C1-C4烷基；R05是氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基、C3-C7环烷基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2H、N(C3-C6炔基)-SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2H、N(C3-C7环烷基)-SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR057R058、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR060CO2R059；R06是氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基、C3-C7环烷基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4-烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)-SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR061R062、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR064CO2R063；R07是苯基、C1-C4烷基、C1-C4烷氧基或-NR08R09；R08和R09分别独立地为C1-C4烷基、苯基、或被下列基团取代的苯基卤素、硝基、氰基、C1-C4烷基、C1-C4烷氧基、C1-C4烷硫基、-CO2R066、-COR067、C1-C4烷基磺酰基、C-C4烷基亚磺酰基或C1-C4卤代烷基；或者R08和R09一起形成可被氧、NR065或S间隔的5-元或6-元环；R015、R031、R043、R048、R052、R056、R060和R064分别独立地为氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基或C3-C7环烷基；R025、R026、R027、R028、R029、R030、R032、R033、R034、R035、R036、R037、R040、R041、R042、R045、R046、R047、R049、R050、R053、R054、R055、R057、R058、R059、R061、R062、R053、R065和R068分别独立地为氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基、C3-C7环烷基、苯基、或被下列基团取代的苯基卤素、硝基、氰基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷硫基、C1-C4卤代烷硫基、C1-C4烷基或C1-C4卤代烷基；且R36是C1-C4烷基、C1-C4卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基、或被下列基团取代的C3-C6环烷基卤素、C1-C4烷基、C1-C4卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C4烷氧基羰基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4烷基羰基、二(C1-C4烷基)氨基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基-S(O)2O、C1-C4卤代烷基-S(O)2O、或苯基，所述苯基自身可被下列基团取代卤素、C1-C4烷基、C1-C4卤代烷基、C3-C6链烯基、C3-C6炔基、氰基、硝基或COOH；和b)协同有效量的一种或多种选自下列的化合物式2.1化合物 其中R51是CH2-OMe、乙基或氢；R52是氢，或者R51与R52一起形成基团-CH＝CH-CH＝CH-；和式2.2化合物 其中R53是乙基，R54是甲基或乙基，且R55是-CH(Me)-CH2OMe、<S>-CH(Me)-CH2OMe、CH2OMe或CH2O-CH2CH3；和式2.3化合物 其中R56是CH(Me)-CH2OMe或<S>CH(Me)-CH2OMe；和式2.4化合物 其中R57是氯、甲氧基或甲硫基，R58是乙基，且R59是乙基、异丙基、-C(CN)(CH3)-CH3或叔丁基；和式2.5化合物 其中R60是乙基或正丙基，R61是COO-1/2Ca++、-CH2-CH(Me)S-CH2CH3或基团 且X是氧、N-O-CH2CH3或N-O-CH2CH-CH-Cl；和式2.6化合物 其中R62是氢、甲氧基或乙氧基，R63是氢、甲基、甲氧基或氟，R64是COOMe、氟或氯，R65是氢或甲基，Y是次甲基、C-F或氮，Z是次甲基或氮，且R66是氟或氯；和式2.7化合物 其中R67是氢或-C(O)-S-正辛基；和式2.8化合物 其中R68是溴或碘；和式2.9化合物 其中R69是氯或硝基；和式2.10化合物 其中R70是氟或氯，且R71是-CH2-CH(Cl)-COOCH2CH3或-NH-SO2Me；和式2.11化合物 其中R72是三氟甲基或氯；和式2.12化合物 其中R73是NH2或<S>NH2；和式2.13化合物 其中Y1是氮、次甲基、NH-CHO或N-Me，Y2是氮、次甲基或C-I，Y3是次甲基，Y4是次甲基，或者Y3和Y4一起是硫或C-Cl，Y5是氮或次甲基，Y6是甲基、二氟甲氧基、三氟甲基或甲氧基，Y7是甲氧基或二氟甲氧基，且R74是CONMe2、COOMe、COOC2H5、三氟甲基、CH2-CH2CF3或SO2CH2CH3，或其钠盐(“Me”是甲基)；和式2.13.c化合物 和式2.14化合物 和式2.15化合物 和式2.16化合物 和式2.17化合物 和式2.18化合物 和式2.19化合物 和式2.20化合物 和式2.21化合 和式2.22化合物 和式2.23化合物 和式2.24化合物 和式2.25化合物 和式2.26化合物 和式2.27化合物 和式2.28化合物 和式2.29化合物 和式2.30化合物 和式2.31化合物 和式2.32化合物 和式2.33化合物 and the compound of formula 2.34 和式2.35化合物 和式2.36化合物 和式2.37化合物和式2.38化合物和式2.39化合物和式2.40化合物和式2.41化合物 和式2.42化合物 和式2.43化合物 和式2.44化合物 和式2.45化合物 和式2.46化合物 和式2.47化合物 和式2.48化合物 和式2.49化合物 和式2.50化合物 和式2.51化合物 在上式中，“Me”是甲基。在取代基定义中提及的烷基可以是直链或支链，并且是例如甲基、乙基、正丙基、异丙基、正丁基、仲丁基、异丁基、叔丁基、戊基、己基、庚基、辛基、壬基、癸基、十一烷基和十二烷基及其支链异构体。烷氧基、链烯基和炔基衍生自上述烷基。链烯基和炔基可具有一个或一个以上的不饱和键。
亚烷基可以被一个或多个甲基取代；这样的亚烷基优选未取代。这也适用于所有含有C3-C5环烷基-、C3-C5氧杂环烷基-、C3-C5硫杂环烷基-、C3-C4二氧杂环烷基-、C3-C4二硫杂环烷基-、C3-C4氧硫杂环烷基-和N(CH2)-的基团。
卤素一般是氟、氯、溴或碘。这相应地适用于在其它定义例如卤代烷基或卤代苯基中出现的卤素。
具有1-6个碳原子链长的卤代烷基是例如氟甲基、二氟甲基、三氟甲基、氯甲基、二氯甲基、三氯甲基、2，2，2-三氟乙基、2-氟乙基、2-氯乙基、五氟乙基、1，1-二氟-2，2，2-三氯乙基、2，2，3，3-四氟乙基和2，2，2-三氯乙基、五氟乙基、七氟正丙基、五氟正己基；在R2、R3和尤其是R5的定义中的卤代烷基优选为三氯甲基、二氯氟甲基、二氟氯甲基、二氟甲基、三氟甲基、五氟乙基或七氟正丙基。
合适的卤代链烯基包括被卤素取代一次或多次的链烯基，卤素是氟、氯、溴或碘，尤其是氟或氯，例如2，2-二氟-1-甲基乙烯基、3-氟丙烯基、3-氯丙烯基、3-溴丙烯基、2，3，3-三氟丙烯基、2，3，3-三氯丙烯基和4，4，4-三氟丁-2-烯-1-基。优选的被卤素取代1次、2次或3次的C2-C12链烯基是链长为2-5个碳原子的那些。合适的卤代炔基包括例如被卤素取代一次或多次的炔基，卤素是溴或碘，和尤其是氟或氯，例如3-氟丙炔基、3-氯丙炔基、3-溴丙炔基、3，3，3-三氟丙炔基和4，4，4-三氟-丁-2-炔-1-基。优选的被卤素取代1次、2次或3次的炔基是链长为2-5个碳原子的那些。
烷氧基优选具有1-6个碳原子的链长。烷氧基是例如甲氧基、乙氧基、丙氧基、异丙氧基、正丁氧基、异丁氧基、仲丁氧基或叔丁氧基或戊氧基或己氧基异构体，优选甲氧基和乙氧基。烷基羰基优选为乙酰基或丙酰基。烷氧基羰基是例如甲氧基羰基、乙氧基羰基、丙氧基羰基、异丙氧基羰基、正丁氧基羰基、异丁氧基羰基、仲丁氧基羰基或叔丁氧基羰基，优选甲氧基羰基、乙氧基羰基或叔丁氧基羰基。卤代烷氧基优选具有1-8个碳原子的链长。
卤代烷氧基是例如氟甲氧基、二氟甲氧基、三氟甲氧基、2，2，2-三氟乙氧基、1，1，2，2-四氟乙氧基、2-氟乙氧基、2-氯乙氧基、2，2-二氟乙氧基或2，2，2-三氯乙氧基，优选二氟甲氧基、2-氯乙氧基或三氟甲氧基。
烷硫基优选具有1-8个碳原子的链长。
烷硫基是例如甲硫基、乙硫基、丙硫基、异丙硫基、正丁硫基、异丁硫基、仲丁硫基或叔丁硫基，优选为甲硫基或乙硫基。
烷基亚磺酰基是例如甲基亚磺酰基、乙基亚磺酰基、丙基亚磺酰基、异丙基亚磺酰基、正丁基亚磺酰基、异丁基亚磺酰基、仲丁基亚磺酰基或叔丁基亚磺酰基，优选为甲基亚磺酰基或乙基亚磺酰基。
烷基磺酰基是例如甲基磺酰基、乙基磺酰基、丙基磺酰基、异丙基磺酰基、正丁基磺酰基、异丁基磺酰基、仲丁基磺酰基或叔丁基磺酰基，优选为甲基磺酰基或乙基磺酰基。
烷基氨基是例如甲基氨基、乙基氨基、正丙基氨基、异丙基氨基或丁基氨基异构体。二烷基氨基是例如二甲基氨基、甲基乙基氨基、二乙基氨基、正丙基甲基氨基、二丁基氨基或二异丙基氨基。烷基氨基优选具有1-4个碳原子的链长。烷氧基烷基优选具有1-6个碳原子的链长。烷氧基烷基是例如甲氧基甲基、甲氧基乙基、乙氧基甲基、乙氧基乙基、正丙氧基甲基、正丙氧基乙基、异丙氧基甲基或异丙氧基乙基。烷硫基烷基优选具有1-6个碳原子的链长。烷硫基烷基是例如甲硫基甲基、甲硫基乙基、乙硫基甲基、乙硫基乙基、正丙硫基甲基、正丙硫基乙基、异丙硫基甲基、异丙硫基乙基、丁硫基甲基、丁硫基乙基或丁硫基丁基。
环烷基优选具有3-6个环碳原子，并且可以被一个或多个甲基取代；它们优选未取代，例如环丙基、环丁基、环戊基或环己基。苯基，包括作为取代基例如苯氧基、苄基、苄氧基、苯甲酰基、苯硫基、苯基烷基、苯氧基烷基或甲苯磺酰基的一部分的苯基可以是单取代或多取代形式，对于这种情况，取代基可以按照需要在邻位、间位和/或对位。
本发明还包括式I化合物可以与胺、碱金属和碱土金属碱或季铵碱形成的盐。在作为盐形成剂使用的碱金属和碱土金属氢氧化物当中，可特别提及氢氧化锂、氢氧化钠、氢氧化钾、氢氧化镁和氢氧化钙，尤其是氢氧化钠和氢氧化钾。
适用于形成铵盐的胺的实例是氨以及伯、仲和叔C1-C18烷基案、C1-C4羟基烷基胺和C2-C4烷氧基烷基胺，例如甲基胺、乙基胺、正丙基胺、异丙基胺、四种丁基胺异构体、正戊基胺、异戊基胺、己基胺、庚基胺、辛基胺、壬基胺、癸基胺、十五烷基胺、十六烷基胺、十七烷基胺、十八烷基胺、甲基乙基胺、甲异丙基胺、甲基己基胺、甲基壬基胺、甲基十五烷基胺、甲基十八烷基胺、乙基丁基胺、乙基庚基胺、乙基辛基胺、己基庚基胺、己基辛基胺、二甲基胺、二乙基胺、二-正丙基胺、二异丙基胺、二-正丁基胺、二正戊基胺、二异戊基胺、二己基胺、二庚基胺、二辛基胺、乙醇胺、正丙醇胺、异丙醇胺、N，N-二乙醇胺、N-乙基丙醇胺、N-丁基乙醇胺、烯丙基胺、正丁烯基-2-胺、正戊烯基-2-胺、2，3-二甲基丁烯基-2-胺、二丁烯基-2-胺、正己烯基-2-胺、丙二胺、三甲基胺、三乙基胺、三正丙基胺、三异丙基胺、三正丁基胺、三异丁基胺、三仲丁基胺、三正戊基胺、甲氧基乙基胺和乙氧基乙基胺；杂环胺例如吡啶、喹啉、异喹啉、吗啉、哌啶、吡咯烷、二氢吲哚、奎宁环和吖庚因；伯芳基胺例如苯胺、甲氧基苯胺、乙氧基苯胺、邻甲苯胺、间甲苯胺、对甲苯胺、苯二胺、联苯胺、萘基胺、邻氯苯胺、间氯苯胺和对氯苯胺；但是尤其是三乙基胺、异丙基胺和二异丙基胺。
非常令人惊奇的是，式I活性组分与一种或多种选自式2.1-2.51的活性组分的组合对欲控制杂草的作用超过了一般所预计的加和作用，因此扩大了单独活性组分的作用范围，尤其是在下列两个方面首先，减小了单独的式2.1-2.51化合物的施用量，同时保持了良好的作用水平，其次，对于单独的活性物质以低施用量不可用的情况(从农学角度来看)，本发明组合物可获得良好的杂草控制水平。该结果是杂草谱的显著拓宽，并且提高了在有用植物农作物方面的选择性，如果发生了活性组分的非故意剂量过多，这样的结果是必须的并且可取的。在保持良好控制有用植物农作物中的杂草的同时，本发明组合物还使得在继代农作物中有更大的灵活性。
本发明组合物可用于抗大量在农业上很重要的杂草，例如繁缕属、旱金莲属、地老虎属、马唐属、燕麦属、狗尾草属、芥属、毒麦属、茄属、菜豆属、稗属、藨草属、雨久花属、慈菇属、雀麦属、看麦娘属、石茅高梁、筒轴茅属、莎草属、苘麻属、黄花稔属、苍耳属、苋属、藜属、番薯属、苘蒿属、猪殃殃属、堇菜属和婆婆纳属。本发明组合物适用于农业中的所有常用施用方法，例如芽前施用、苗后施用和种子包衣。本发明组合物尤其适用于控制有用植物农作物例如禾谷类、油菜、甜菜、甘蔗、种植园农作物、稻、玉米和大豆中的杂草，以及适用于非选择性杂草控制。
“农作物”还指通过常规育种或基因工程方法使其对除草剂或除草剂类别耐受的农作物。
优选的本发明组合物包含式I化合物，其中每个R独立地为氢、C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基、C1-C6卤代烷硫基、C1-C6卤代烷基亚磺酰基、C1-C6卤代烷基磺酰基、C1-C6烷氧基羰基、C1-C6烷基羰基、C1-C6烷基氨基、二(C1-C6烷基)氨基、C1-C6烷基氨基磺酰基、二(C1-C6烷基)氨基磺酰基、-N(R1)-S-R2、-N(R3)-SO-R4、-N(R5)-SO2-R6、硝基、氰基、卤素、羟基、氨基、苄硫基、苄基亚磺酰基、苄基磺酰基、苯基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基；其中所述苯基自身可被下列基团单取代、二取代或三取代C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R45、NR46R47、卤素、氰基、硝基、苯基或苄硫基，其中后面提及的苯基和苄硫基自身可在苯环上被C1-C8烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；或者每个R独立地为5-10元单环或稠合二环系，所述环系可以是芳环或部分饱和环，并且可以含有1-4个选自氮、氧和硫的杂原子；其中所述环系直接与吡啶环连接，或者经由C1-C4亚烷基与吡啶环连接，并且每个环系不可以含有2个以上的氧原子，不可以含有2个以上的硫原子，所述环系自身可被下列基团单取代、二取代或三取代C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R7、NR8R9、卤素、氰基、硝基、苯基或苄硫基，其中所述苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代，并且在杂环中的氮上的取代基不是卤素。
还优选的本发明组合物包含式Ia化合物作为式I化合物 其中R48是C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基、C1-C6卤代烷基、或5-10元单环或稠合二环系，所述环系可以是芳环或部分饱和环，并且可以含有1-4个选自氮、氧和硫的杂原子，其中所述环系直接与吡啶环连接，或者经由C1-C4亚烷基与吡啶环连接，并且每个环系不可以含有2个以上的氧原子，不可以含有2个以上的硫原子，所述环系自身可被下列基团单取代、二取代或三取代C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R7、NR8R9、卤素、氰基、硝基、苯基或苄硫基，其中所述苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代，并且在杂环中的氮上的取代基不是卤素；R49是氢、C1-C6烷基、C1-C6卤代烷基、卤素、或苯基，所述苯基可被下列基团取代C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基，且R50是C1-C6卤代烷基。
在该组化合物当中，其中R48是C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基或C1-C6卤代烷基的那些是优选的。
对于本发明组合物还优选的是，在式I中，Q是基团Q2或Q3，其中尤其是，在基团Q2中，R23是羟基，在基团Q3中，R40是羟基。在该组化合物当中，其中m是2，且一个取代基R是C1-C4烷氧基-C1-C4烷基或C1-C4烷氧基-C1-C4烷氧基-C1-C4烷基的化合物是特别重要的。
进一步优选的本发明协同混合物包含式I化合物和下列化合物作为活性组分式2.2.a化合物 (2.2.a，aRS，1’S(-)N-(1’-甲基-2’-甲氧基乙基)-N-氯乙酰基-2-乙基-6-甲基苯胺)或式2.2.b化合物 或式2.2化合物，其中R3是乙基、R4是甲基、且R5是乙氧基甲基，或式2.2化合物，其中R3是乙基、R4是乙基、且R5是甲氧基甲基，或化合物2.3，或式2.30化合物，或式2.4化合物，或式2.13化合物，或式2.14化合物，或式2.6化合物，其中R12是氢、Z是次甲基、R13是甲基、Y是氮、R14是氟、R15是氢、且R16是氟，或者R12是甲氧基、Z是次甲基、R13是甲氧基、Y是次甲基、R14是氯、R15是甲基、且R16是氯，或式2.7化合物，其中R17是-C(O)-S-正辛基，或式2.12化合物，或式2.18化合物，或式2.19化合物，或式2.21化合物，或式2.25化合物，或式2.33化合物，或式2.45化合物，或式2.1化合物。
尤其优选的本发明协同混合物包含式I化合物和下列化合物作为活性组分式2.2.a化合物 (2.2.a，aRS，1’S(-)N-(1’-甲基-2’-甲氧基乙基)-N-氯乙酰基-2-乙基-6-甲基苯胺)或式2.2.b化合物 或式2.2化合物，其中R3是乙基、R4是甲基、且R5是乙氧基甲基，或式2.2化合物，其中R3是乙基、R4是乙基、且R5是甲氧基甲基，或化合物2.3，或式2.30化合物。
已经发现，式I化合物与式2.2a化合物 (2.2.a，aRS，1’S(-)N-(1’-甲基-2’-甲氧基乙基)-N-氯乙酰基-2-乙基-6-甲基苯胺)的组合是特别有效的，尤其优选的式I化合物是在下文表1中列出的化合物1.001。
式I化合物可通过类似于在WO 97/46530中描述的方法制得，所述方法包括a)在惰性有机溶剂中，在碱存在下，将式II化合物 其中R和m如式I中所定义，且X是离去基团例如卤素，与式III、IV、V或VI化合物反应 其中R20、R23、R30和R40是羟基，且其它取代基如式I所定义，以生成式VII、VIII、IX或X化合物， 然后将这些化合物异构化，例如在碱和催化量的二甲基氨基吡啶(DMAP)或氰化物源存在下异构化；或者b)在惰性有机溶剂中，在碱和偶联剂存在下，将式XI化合物 其中R和m如式I中所定义，与式III、IV、V或VI化合物反应，以形成式VII、VIII、IX或X化合物，然后将所得化合物异构化，例如按照在路线a)中描述的方法异构化。
其中Q是基团Q5的式I化合物 其中Z是硫，且R36和R01如式I中所定义，可按照类似于已知方法(例如在WO 97/43270中描述的方法)的方法制得，所述方法包括a)在碱、二硫化碳、和式XIII烷化剂R01-X1(XIII)，其中R01如式I中所定义，且X1是离去基团例如卤素或磺酸酯，存在下，将式XII化合物 其中R36、R和m如上所定义，转化成式XIV化合物 其中Z是硫，R、R01、R36和m如上所定义，然后任选在溶剂中，在碱存在下，用羟基胺盐酸盐将该化合物环化，以形成式Ie化合物 其中Z是硫，且R、R36、R01和m如上所定义，然后用氧化剂例如间氯过苯甲酸(m-CPBA)将该化合物氧化。
下列反应方案1和2中更详细地描述了式I化合物的制备。反应方案1路线a) 路线b) 含有基团Q1、Q2、Q3和Q4，其中R20、R23、R30和R40是羟基的式I化合物尤其可按照上述反应方案制得。反应方案2 为了制备其中Q是基团Q1-Q4，且R20、R23、R30和R40是羟基的式I化合物，可依据反应方案1路线a)使用式II羧酸衍生物作为原料，其中X是离去基团，例如卤素如碘、溴或尤其是氯，N-氧基邻苯二甲酰亚胺或N，O-二甲基羟基氨基或活化酯基团例如 (由二环己基碳二亚胺(DCC)和适当羧酸形成的)或 (由N-乙基-N’-(3-二甲基氨基丙基)碳二亚胺(EDC)和适当羧酸形成的)。在惰性有机溶剂例如卤代烃如二氯甲烷，腈例如乙腈，或芳烃例如甲苯中，在碱例如烷基胺如三乙胺，芳族胺例如吡啶或4-二甲基氨基吡啶(DMAP)存在下，将这些化合物与式III、IV、V或VI二酮衍生物反应，以形成式VII、VIII、IX和X异构体烯醇醚。酯化在0℃-110℃进行。
式VII、VIII、IX和X酯衍生物异构化成式I二酮衍生物(其中R20、R23、R30和R40是羟基)可例如按照类似于EP 369 803的方法，在碱例如烷基胺如三乙胺，碳酸盐例如碳酸钾，和催化量的DMAP或氰化物源例如丙酮氰醇或氰化钾存在下来进行。
按照反应方案1、路线b)，所需的式I二酮(其中R20、R23、R30和R40是羟基)可这样获得，例如按照类似于《化学通信》(Chem.Lett.)1975，1045的方法，在惰性溶剂例如卤代烃如二氯甲烷，腈例如乙腈，或芳烃例如甲苯中，在碱例如烷基胺如三乙胺，和偶联剂例如2-氯-1-甲基-吡啶鎓碘化物存在下，用式III、IV、V或VI二酮衍生物将式XI羧酸酯化。根据所用的溶剂，酯化可在0℃-110℃进行，并且如路线a)所述，首先生成式I异构酯，并且如路线a)所述，例如在碱和催化量的DMAP，或氰化物源存在下，式I异构酯可异构化以形成式I二酮衍生物(其中R20、R23、R30和R40是羟基)。
其中Q是基团Q5的式I化合物的制备可这样进行，即按照反应方案2，例如采用类似于《合成》(Synthesis)1991，301；同前(ibid.)1988，793或《四面体》(Tetrahedron)32，3055(1976)的方法，在碱例如碳酸盐如碳酸钾，金属氢化物如氢化钠，或者以氟化钾/铝，和式III烷基化剂存在下，其中X1是离去基团如卤素例如碘、溴或尤其是氯、R25OSO2O-、CH3SO2O-或 将式XII b-二酮衍生物与二硫化碳反应。该反应优选在溶剂例如酰胺如N，N-二甲基甲酰胺(DMF)，亚砜例如二甲亚砜(DMSO)，或腈例如乙腈中进行。在碱例如乙酸钠存在下，在溶剂例如醇如乙醇或醚例如四氢呋喃中，使用盐酸羟胺将形成的式XIV乙烯酮缩乙硫醇环化，以形成其中Z是S-的式Ie化合物。该环化反应在0℃-100℃进行。可任选按照类似于标准方法的方法，例如使用过酸如间氯过苯甲酸(m-CPBA)或过乙酸将式Ie化合物(Z＝S)氧化，以形成相应的式Ie砜和亚砜(Z＝SO-或SO2-)，其中可通过氧化剂的量来控制硫原子的氧化程度(Z＝SO-或SO2-)。
式Ie化合物的氧化(Z＝SO-或SO2-)是按照例如在H.O.House，《现代合成反应》″Modern Synthetic Reactions″W.A.Benjamin，Inc.，Menlo Park，California，1972，p.334-335和353-354中描述的方法进行的。
在反应方案1(路线a)中，其中X是离去基团例如卤素如溴、碘或尤其是氯的式II活化羧酸衍生物可按照已知的标准方法，例如在C.Ferri″Reaktionen der organischen Synthese″，Georg Thieme Verlag，Stuttgart，1978，p.461 ff中描述的方法以及如下述反应方案3所示的方法制得。反应方案3 按照反应方案3，式II化合物(X＝离去基团)或II(X＝卤素)的制备可通过例如使用卤化剂来进行，所述卤化剂是例如亚硫酰卤如亚硫酰氯或亚硫酰溴；卤化磷或磷酰卤例如五氯化磷或三氯氧化磷或五溴化磷或磷酰溴；或草酰卤例如草酰氯，或通过使用用于形成活化酯的试剂例如N，N’-二环己基碳二亚胺(DCC)或N-乙基-N’-(3-二甲基氨基丙基)碳二亚胺(EDC)来进行。在作为卤化剂的式X化合物中，X是离去基团，例如卤素如氟、溴或碘和尤其是氯，且W1是例如PCl2、SOCl、SOBr或ClCOCO。
该方法任选在惰性有机溶剂例如脂族烃、卤代脂族烃、芳烃或卤代芳烃例如正己烷、苯、甲苯、二甲苯、二氯甲烷、1，2-二氯乙烷或氯苯中，在-20℃-该反应混合物的回流温度下、优选40-150℃温度下，在催化量的N，N-二甲基甲酰胺存在下进行。这样的反应一般是已知的，并且以关于离去基团X的多种变化形式描述于文献中。
式III、IV、V和VI化合物是已知的，并且可按照类似于在例如WO92/07837、DE 3 818 958、EP 338 992和DE 3 902 818中描述的方法制得。
在反应方案2中的式XII化合物可通过标准方法，由例如相应的式II化合物制得 其中R和m如式I中所定义，且X是离去基团例如卤素，例如经由克莱森缩合而制得，或者通过与式XV酮基羧酸盐反应由式II化合物制得 其中R36如式I中所定义，且M+是碱金属离子(参见例如WO 96/26192)。
式II和XI化合物是已知的，并且可按照类似于在例如WO 97/46530，《杂环》(Heterocycles)，48，779(1998)，《杂环》，46，129(1997)或《四面体通信》(Tetrahedron Letters)，1749(1998)中描述的方法制得。
为了制备所有其官能团取决于(R)m定义的其它式I化合物，可使用多种已知的标准方法例如烷基化、卤化、酰化、酰胺化、肟化、氧化和还原，合适的制备方法的选择由各中间体中的取代基的性质(反应性)决定。WO97/46353中描述了这样的反应的实例。
在式I范围内的所有其它化合物可按照考虑吡啶基和Q基团的化学性质的简单方法来制得。
式I终产物可通过浓缩或将溶剂蒸发以常规方式分离，并通过在固体残余物不易溶于其中的溶剂例如醚、芳烃或氯代烃中将固体残余物重结晶或研制，通过蒸馏或使用柱色谱与合适的洗脱剂来纯化。
此外，本领域技术人员熟悉其中一些反应应当有利进行的顺序以防止可能的副反应。
当合成不能直接使得纯的异构体分离出来时，产物可呈两种或更多种异构体的混合物的形式。可按照自身已知的方法分离异构体。制备实施例实施例P1制备4-羟基-3-(2-甲基-6-三氟甲基-吡啶-3-羰基)-二环[3.2.11]辛-3-烯-2-酮将6.68g(0.0305mol)2-甲基-6-三氟甲基-烟酸甲酯(按照在《杂环》，46，129(1997)中描述的方法制得的)溶解在250ml甲醇/水(3∶1混合物)中，并在22℃分批加入1.92g(0.046mol)氢氧化锂水合物。在22℃保持4小时后，将该反应混合物加到乙酸乙酯和2N盐酸中；用水将有机相洗涤3次，用硫酸钠干燥，并通过蒸发浓缩，用少量己烷研制残余物。过滤后，获得了5.69g(产率为90％)预期的2-甲基-6-三氟甲基烟酸，熔点为147-149℃。
将所得2-甲基-6-三氟甲基-烟酸(2.0g，0.0098mol)溶解在20ml草酰氯中。加入3滴二甲基甲酰胺，并将该混合物回流1小时。然后使用旋转蒸发仪将该混合物浓缩，将残余物(2-甲基-6-三氟甲基烟酰氯)置于30ml二氯甲烷中。在0℃，加入2.7ml(0.0196mol)三乙胺和0.12g(0.00098mol)二甲基氨基吡啶，然后滴加溶解在20ml二氯甲烷中的1.49g(0.0108mol)二环[3.2.1]辛-2，4-二酮。在22℃保持3小时后，通过与2N盐酸一起振摇来萃取该反应混合物。将分离的二氯甲烷相用水洗涤，然后通过与10％碳酸氢钠水溶液振摇来萃取，用硫酸钠干燥，并通过蒸发浓缩。获得了3.18g(产率为100％)2-甲基-6-三氟甲基烟酸4-氧代二环[3.2.1]辛-2-烯-2-基酯，为油状物，可不用进一步纯化直接使用。将3.02g(0.0093mol)甲基-6-三氟甲基-烟酸4-氧代二环[3.2.1]辛-2-烯-2-基酯和1.9ml(0.0136mol)三乙胺溶解在45ml乙腈中。在22℃加入0.01ml丙酮氰醇。在22℃保持18小时后，将该反应混合物倒入水与2N盐酸的混合物中，并通过与乙酸乙酯振摇来萃取。将乙酸乙酯相依次用水和盐水洗涤，用硫酸钠干燥，并通过蒸发浓缩，将残余物溶解在少量温热的丙酮中。在静置时产物结晶出来。过滤后，获得了0.99g(产率为33％)预期的4-羟基-3-(2-甲基-6-三氟甲基-吡啶-3-羰基)-二环[3.2.1]辛基-3-烯-2-酮，为白色结晶形式(m.p.75-77℃)。实施例P2(5-环丙基-3-甲硫基异噁唑-4-基)-(2-甲基-6-三氟甲基-吡啶-3-基)-甲酮将14.8g(0.080mol)3-环丙基-3-氧代丙酸叔丁酯溶解在25mlMeOH中，加入1.93g(0.080mol)镁。滴加7ml四氯化碳，同时在冰浴中冷却，并将该反应混合物在22℃搅拌1小时以使反应完全。通过蒸发将其浓缩后，在22℃将残余物悬浮在100ml乙腈中，并滴加溶解在50ml乙腈中的16.31g(0.073mol)2-甲基-6-三氟甲基-烟酰氯(按照实施例P1中描述的方法制得的)。6小时后，将该反应混合物置于乙酸乙酯中，并用饱和碳酸氢钠溶液洗涤。将分离出的乙酸乙酯相用水洗涤，用硫酸钠干燥，并通过蒸发浓缩。将残余物溶解在160ml二氯甲烷中，并在22℃滴加10ml三氟乙酸。18小时后，将该反应混合物倒入水中，并用二氯甲烷萃取。将二氯甲烷相依次用水和盐水洗涤，用硫酸钠干燥，并通过蒸发浓缩。获得了17.3g(产率为88％)1-环丙基-3-(2-甲基-6-三氟甲基-吡啶-3-基)-丙-1，3-二酮，为油状物，可不用进一步纯化直接使用。
将所得1-环丙基-3-(2-甲基-6-三氟甲基-吡啶-3-基)-丙-1，3-二酮(15.0g，0.055mol)溶解在150ml二甲基甲酰胺中，在0℃分批加入50g以氧化铝为载体的氟化钾(Alox)(0.0055mol/g，0.276mol)。5分钟后，加入6.7g(0.088mol)二硫化碳。2小时后，滴加23.6g(0.166mol)甲基碘，并将该反应混合物在22℃加热。2小时后，过滤出Alox，将滤液倒入水中，并通过与乙酸乙酯振摇来萃取。将乙酸乙酯相依次用水和盐水洗涤，用硫酸钠干燥，并通过蒸发浓缩。通过硅胶色谱纯化残余物(洗脱剂乙酸乙酯/己烷15/1)。获得了12.0g(产率60％)2-(二-甲硫基-亚甲基)-1-环丙基-3-(2-甲基-6-三氟甲基-吡啶-3-基)-丙-1，3-二酮，为固体。
将12.0g(0.033mol)该产物与5.4g(0.066mol)无水乙酸钠一起悬浮在120ml乙醇中。加入4.6g(0.066mol)盐酸羟胺，并将该混合物在22℃搅拌5小时。然后再加入2.7g无水乙酸钠和2.3g盐酸羟胺。18小时后，用水将该反应混合物稀释，并用乙酸乙酯萃取。将乙酸乙酯相依次用水和盐水洗涤，用硫酸钠干燥，并通过蒸发浓缩。用少量乙酸乙酯研制，获得了9.0g(79.5％)所需产物，为白色结晶(m.p.103-104℃)。实施例P3(5-环丙基-3-甲基亚磺酰基异噁唑-4-基)-(2-甲基-6-三氟甲基-吡啶-3-基)-甲酮将1.50g(0.0043mol)(5-环丙基-3-甲硫基异噁唑-4-基)-(2-甲基-6-三氟甲基-吡啶-3-基)-甲酮溶解在30ml丙酮/水(2∶1混合物)中，并在22℃分批加入1.02g(0.0048mol)偏高碘酸钠。5小时后，使用旋转蒸发仪通过蒸发将该反应混合物浓缩。将残余物置于水和乙酸乙酯中。用硫酸钠将乙酸乙酯相干燥，并通过蒸发浓缩。通过硅胶色谱纯化残余物(洗脱剂乙酸乙酯/己烷3/1)。获得了0.8g(51％)所需产物，为白色结晶(m.p.96-97℃)。实施例P4制备3-羟基-4，4-二甲基-2-(2-甲基-6-三氟甲基-吡啶-3-羰基)-环己-2-烯酮(A2-B24)将6.68g(0.0305mol)2-甲基-6-三氟甲基-烟酸甲酯(按照在《杂环》，46，129(1997)中描述的方法制得的)溶解在250ml甲醇/水(3∶1混合物)中，并在22℃分批加入1.92g(0.046mol)氢氧化锂水合物。在22℃保持4小时后，将该反应混合物加到乙酸乙酯和2N盐酸中；用水将有机相洗涤3次，用硫酸钠干燥，并通过蒸发浓缩，用少量己烷研制残余物。过滤后，获得了5.69g(产率为90％)预期的2-甲基-6-三氟甲基烟酸，熔点为147-149℃。
将所得2-甲基-6-三氟甲基-烟酸(1.026g，0.005mol)溶解在20ml草酰氯中。加入3滴二甲基甲酰胺，并将该混合物回流1小时。然后用旋转蒸发仪通过蒸发将该混合物浓缩，并将残余物(2-甲基-6-三氟甲基-烟酰氯)置于100ml二氯甲烷中。在0℃加入1.6ml(0.0115mol)三乙胺和0.7g(0.005mol)4，4-二甲基-环己烷-1，3-二酮。在22℃保持2小时后，使用旋转蒸发仪除去溶剂，将剩余的残余物溶解在55ml乙腈中，为了使该中间体重排，加入0.15ml(0.0016mol)丙酮氰醇和0.79ml(0.0057mol)三乙胺。在室温搅拌4小时后，通过蒸发将该反应溶液浓缩。通过硅胶色谱纯化剩余的浆状物。将通过用甲苯、乙醇、二氧杂环己烷、三乙胺和水的混合物(100∶40∶20∶20∶5体积份)(使用所述混合物作为流动相Rf＝0.39)洗脱而获得的浅黄色粘稠油状物溶解在二氯甲烷中，并依次用75ml盐酸5％和75ml水洗涤。用硫酸钠将有机溶液干燥后，通过蒸发浓缩，获得了1.05g(63％)纯的标题化合物。1H NMR(d6-DMSO，δppm)1.342，s，6H2.088，t，J9Hz，2H2.685，s，3H2.982，t，J9Hz，2H8.030，d，J8.1Hz，1H8.094，d，J8.1Hz，1H。实施例P5制备5-甲基-5-三氟甲基-环己烷-1，3-二酮(实施例B1066)将0.64g钠加到40ml乙醇中，加入3.23ml乙酸甲酯和4.9 g 4，4，4-三氟-3-甲基-丁-2-烯酸异丙酯，并将该混合物在沸点温度加热18小时。用稀盐酸和乙酸乙酯萃取后，通过蒸发浓缩。将保留未纯化的2-甲基-4，6-二氧代-2-三氟甲基-环己烷甲酸甲酯在9.1g氢氧化钠存在下在甲醇与水的混合物中于沸点温度酯化。然后用盐酸将该混合物酸化，并用新鲜的乙酸乙酯萃取。重结晶(乙酸乙酯)后，获得了纯的5-甲基-5-三氟甲基环己烷-1，3-二酮，熔点为150-152℃。实施例P6制备2-羟基-1-甲氧基-5-甲基-4-氧代环己-2-烯甲酸甲酯(B1069)用35.8g甲醇钠在65ml二甲亚砜中制成30％溶液，在30-35℃用20分钟加入16.7g 3-甲基-3-丁烯-2-酮与32.4g甲氧基丙二酸二甲酯。将该混合物在35℃搅拌1小时，用盐酸酸化，然后用二氯甲烷萃取数次。将有机相用水洗涤，干燥并浓缩。通过从热的乙酸乙酯和己烷中结晶，获得了纯的2-羟基-1-甲氧基-5-甲基-4-氧代-环己-2-烯羧酸甲酯，熔点为117-117.5℃。实施例P7制备2-羟基-1-甲氧基-5-甲基-3-(2-甲基-6-三氟甲基-吡啶-3-羰基)-4-氧代-环己-2-烯羧酸甲酯(A2-B1069)将2.23g新制的2-甲基-6-三氟甲基-烟酰氯加到2.14g 2-羟基-1-甲氧基-5-甲基-4-氧代-环己-2-烯甲酸甲酯和2.02g三乙胺在30ml乙腈内的混合物中。约30分钟后，加入0.065g氰化钾，并将该混合物搅拌18小时。然后在pH2用水和乙酸乙酯萃取，用硫酸镁干燥，并通过蒸发浓缩。经由硅胶过滤(流动相∶乙酸乙酯/甲醇/三乙胺85∶10∶5)，获得了纯的2-羟基-1-甲氧基-5-甲基-3-(2-甲基-6-三氟甲基-吡啶-3-羰基)-4-氧代-环己-2-烯羧酸甲酯，为粘稠的油状物。实施例P8制备3-羟基-4-甲氧基-6-甲基-2-(2-甲基-6-三氟甲基-吡啶-3-羰基)-环己-2-烯酮(A2-B1070)将0.586g氢氧化钾加到在二氧杂环己烷/水(5∶3)内的1.4g 2-羟基-1-甲氧基-5-甲基-3-(2-甲基-6-三氟甲基-吡啶-3-羰基)-4-氧代-环己-2-烯羧酸甲酯中，并将该混合物搅拌3小时。然后将该混合物酸化(pH3)，并用新鲜的乙酸乙酯萃取。通过类似于实施例P7的色谱法纯化粗产物，获得了3-羟基-4-甲氧基-6-甲基-2-(2-甲基-6-三氟甲基-吡啶-3-羰基)-环己-2-烯酮，为粘稠的油状物(根据1H-NMR，3种互变异构形式的混合物)。
按照类似方式，并使用在一般反应方案1和2以及其中所提及的参考文献中描述的方法，还可以制得在下表中列出的化合物。在下表中，Ph是苯基，且CC是乙炔基。表1式Ib化合物 化合物.
R75R76R77R78m.p.(℃)序号1.001CH3CF3H H 75-771.002CH3CH2CF3H H1.003(CH3)2CHCF3H H 111-1121.004CH3(CH2)3CF3H H1.005PhCF3H H 油状物1.006CH2BrCF3H H1.007CH2OCH3CF3H H 124-1261.008CH2SMe CF3H H 油状物1.009CH2SO2MeCF3H H 55-551.010SCH3CF3H H化合物R75R76R77R78m.p.(℃)序号1.011 SOCH3CF3HH1.012 SO2CH3CF3HH1.013 SPhCF3HH1.014 SOPh CF3HH1.015 SO2Ph CF3HH1.016 CH3CF3CF2HH1.017 CH3CH2CF3CF2HH1.018 (CH3)2CH CF3CF2HH1.019 CH3(CH2)3CF3CF2HH1.020 Ph CF3CF2HH1.021 CH2Br CF3CF2HH1.022 CH2OCH3CF3CF2HH1.023 CH2SMeCF3CF2HH1.024 CH2SO2Me CF3CF2HH1.025 SCH3CF3CF2HH1.026 SOCH3CF3CF2HH1.027 SO2CH3CF3CF2HH1.028 SPhCF3CF2HH1.029 SOPh CF3CF2HH1.030 SO2Ph CF3CF2HH1.031 CH3CHF2HH1.032 CH3CH2CHF2HH1.033 (CH3)2CH CHF2HH1.034 CH3(CH2)3CHF2HH1.035 Ph CHF2HH1.036 CH2Br CHF2HH1.037 CH2OCH3CHF2HH1.038 CH2SMeCHF2HH1.039 CH2SO2Me CHF2HH1.040 SCH3CHF2HH1.041 SOCH3CHF2HH1.042 SO2CH3CHF2HH化合物R75R76R77R78m.p.(℃)序号1.043 SPhCHF2H H1.044 SOPh CHF2H H1.045 SO2Ph CHF2H H1.046 CH3CF3CH3H1.047 CH3CH2CF3CH3H1.048 (CH3)2CH CF3CH3H1.049 CH3(CH2)3CF3CH3H1.050 Ph CF3CH3H1.051 CH2Br CF3CH3H1.052 CH2OCH3CF3CH3H1.053 CH2SMeCF3CH3H1.054 CH2SO2Me CF3CH3H1.055 SCH3CF3CH3H1.056 SOCH3CF3CH3H1.057 SO2CH3CF3CH3H1.058 SPhCF3CH3H1.059 SOPh CF3CH3H1.060 SO2Ph CF3CH3H1.061 CH3CF3CF2CH3H1.062 CH3CH2CF3CF2CH3H1.063 (CH3)2CH CF3CF2CH3H1.064 CH3(CH2)3CF3CF2CH3H1.065 Ph CF3CF2CH3H1.066 CH2Br CF3CF2CH3H1.067 CH2OCH3CF3CF2CH3H1.068 CH2SMeCF3CF2CH3H1.069 CH2SO2Me CF3CF2CH3H1.070 SCH3CF3CF2CH3H1.071 SOCH3CF3CF2CH3H1.072 SO2CH3CF3CF2CH3H1.073 SPhCF3CF2CH3H1.074 SOPh CF3CF2CH3H化合物R75R76R77R78m.p.(℃)序号1.075SO2PhCF3CF2CH3H1.076CH3CHF2CH3H1.077CH3CH2CHF2CH3H1.078(CH3)2CHCHF2CH3H1.079CH3(CH2)3CHF2CH3H1.080PhCHF2CH3H1.081CH2BrCHF2CH3H1.082CH2OCH3CHF2CH3H1.083CH2SMe CHF2CH3H1.084CH2SO2MeCHF2CH3H1.085SCH3CHF2CH3H1.086SOCH3CHF2CH3H1.087SO2CH3CHF2CH3H1.088SPh CHF2CH3H1.089SOPh CHF2CH3H1.090SO2PhCHF2CH3H1.091CH3CF3HCH392-941.092CH3CH2CF3HCH31.093(CH3)2CHCF3HCH31.094CH3(CH2)3CF3HCH31.095PhCF3HCH31.096CH2BrCF3HCH31.097CH2OCH3CF3HCH31.098CH2SMe CF3HCH31.099CH2SO2MeCF3HCH31.100SCH3CF3HCH31.101SOCH3CF3HCH31.102SO2CH3CF3HCH31.103SPh CF3HCH31.104SOPh CF3HCH31.105SO2PhCF3HCH3
表2式Ic化合物 化合物.R75R76R77R78m.p.(℃)序号2.001 CH3CF3H H 107-1092.002 CH3CH2CF3H H 油状物2.003 (CH3)2CH CF3H H 油状物2.004 CH3(CH2)3CF3H H2.005 PhCF3H H 油状物2.006 CH2Br CF3H H2.007 CH2OCH3CF3H H2.008 CH2SMe CF3H H2.009 CH2SO2Me CF3H H2.010 SCH3CF3H H2.011 SOCH3CF3H H2.012 SO2CH3CF3H H2.013 SPh CF3H H2.014 SOPh CF3H H2.015 SO2PhCF3H H2.016 CH3CF3CF2H H2.017 CH3CH2CF3CF2H H2.018 (CH3)2CHCF3CF2H H2.019 CH3(CH2)3CF3CF2H H2.020 PhCF3CF2H H2.021 CH2BrCF3CF2H H2.022 CH2OCH3CF3CF2H H化合物R75R76R77R78m.p.(℃)序号2.023 CH2SMe CF3CF2H H2.024 CH2SO2Me CF3CF2H H2.025 SCH3CF3CF2H H2.026 SOCH3CF3CF2H H2.027 SO2CH3CF3CF2H H2.028 SPh CF3CF2H H2.029 SOPh CF3CF2H H2.030 SO2Ph CF3CF2H H2.031 CH3CHF2H H2.032 CH3CH2CHF2H H2.033 (CH3)2CH CHF2H H2.034 CH3(CH2)3CHF2H H2.035 Ph CHF2H H2.036 CH2Br CHF2H H2.037 CH2OCH3CHF2H H2.038 CH2SMe CHF2H H2.039 CH2SO2Me CHF2H H2.040 SCH3CHF2H H2.041 SOCH3CHF2H H2.042 SO2CH3CHF2H H2.043 SPh CHF2H H2.044 SOPh CHF2H H2.045 SO2Ph CHF2H H2.046 CH3CF3CH3H2.047 CH3CH2CF3CH3H2.048 (CH3)2CH CF3CH3H2.049 CH3(CH2)3CF3CH3H2.050 PhCF3CH3H2.051 CH2Br CF3CH3H2.052 CH2OCH3CF3CH3H2.053 CH2SMe CF3CH3H2.054 CH2SO2Me CF3CH3H化合物R75R76R77R78m.p.(℃)序号2.055 SCH3CF3CH3H2.056 SOCH3CF3CH3H2.057 SO2CH3CF3CH3H2.058 SPh CF3CH3H2.059 SOPh CF3CH3H2.060 SO2PhCF3CH3H2.061 CH3CF3CF2CH3H2.062 CH3CH2CF3CF2CH3H2.063 (CH3)2CHCF3CF2CH3H2.064 CH3(CH2)3CF3CF2CH3H2.065 PhCF3CF2CH3H2.066 CH2BrCF3CF2CH3H2.067 CH2OCH3CF3CF2CH3H2.068 CH2SMe CF3CF2CH3H2.069 CH2SO2MeCF3CF2CH3H2.070 SCH3CF3CF2CH3H2.071 SOCH3CF3CF2CH3H2.072 SO2CH3CF3CF2CH3H2.073 SPh CF3CF2CH3H2.074 SOPh CF3CF2CH3H2.075 SO2PhCF3CF2CH3H2.076 CH3CHF2CH3H2.077 CH3CH2CHF2CH3H2.078 (CH3)2CHCHF2CH3H2.079 CH3(CH2)3CHF2CH3H2.080 PhCHF2CH3H2.081 CH2BrCHF2CH3H2.082 CH2OCH3CHF2CH3H2.083 CH2SMe CHF2CH3H2.084 CH2SO2MeCHF2CH3H2.085 SCH3CHF2CH3H2.086 SOCH3CHF2CH3H化合物R75R76R77R78m.p.(℃)序号2.087 SO2CH3CHF2CH3H2.088 SPhCHF2CH3H2.089 SOPh CHF2CH3H2.090 SO2Ph CHF2CH3H2.091 CH3CF3HCH32.092 CH3CH2CF3HCH32.093 (CH3)2CH CF3HCH32.094 CH3(CH2)3CF3HCH32.095 Ph CF3HCH32.096 CH2Br CF3HCH32.097 CH2OCH3CF3HCH32.098 CH2SMeCF3HCH32.099 CH2SO2Me CF3HCH32.100 SCH3CF3HCH32.101 SOCH3CF3HCH32.102 SO2CH3CF3HCH32.103 SPhCF3HCH32.104 SOPh CF3HCH32.105 SO2Ph CF3HCH3表3式Id化合物 化合物.
R75R76R77R78m.p.(℃)序号化合物R75R76R77R78m.p.(℃)序号3.001 CH3CF3H H3.002 CH3CH2CF3H H3.003 (CH3)2CH CF3H H3.004 CH3(CH2)3CF3H H3.005 PhCF3H H3.006 CH2BrCF3H H3.007 CH2OCH3CF3H H3.008 CH2SMe CF3H H3.009 CH2SO2MeCF3H H3.010 SCH3CF3H H3.011 SOCH3CF3H H3.012 SO2CH3CF3H H3.013 SPh CF3H H3.014 SOPh CF3H H3.015 SO2PhCF3H H3.016 CH3CF3CF2H H3.017 CH3CH2CF3CF2H H3.018 (CH3)2CH CF3CF2H H3.019 CH3(CH2)3CF3CF2H H3.020 PhCF3CF2H H3.021 CH2BrCF3CF2H H3.022 CH2OCH3CF3CF2H H3.023 CH2SMe CF3CF2H H3.024 CH2SO2MeCF3CF2H H3.025 SCH3CF3CF2H H3.026 SOCH3CF3CF2H H3.027 SO2CH3CF3CF2H H3.028 SPh CF3CF2H H3.029 SOPh CF3CF2H H3.030 SO2PhCF3CF2H H3.031 CH3CHF2H H化合物 R75R76R77R78m.p.(℃)序号3.032CH3CH2CHF2HH3.033(CH3)2CH CHF2HH3.034CH3(CH2)3CHF2HH3.035PhCHF2HH3.036CH2Br CHF2HH3.037CH2OCH3CHF2HH3.038CH2SMe CHF2HH3.039CH2SO2Me CHF2HH3.040SCH3CHF2HH3.041SOCH3CHF2HH3.042SO2CH3CHF2HH3.043SPh CHF2HH3.044SOPh CHF2HH3.045SO2Ph CHF2HH3.046CH3CF3CH3H3.047CH3CH2CF3CH3H3.048(CH3)2CH CF3CH3H3.049CH3(CH2)3CF3CH3H3.050PhCF3CH3H3.051CH2Br CF3CH3H3.052CH2OCH3CF3CH3H3.053CH2SMe CF3CH3H3.054CH2SO2Me CF3CH3H3.055SCH3CF3CH3H3.056SOCH3CF3CH3H3.057SO2CH3CF3CH3H3.058SPh CF3CH3H3.059SOPh CF3CH3H3.060SO2Ph CF3CH3H3.061CH3CF3CF2CH3H3.062CH3CH2CF3CF2CH3H3.063(CH3)2CH CF3CF2CH3H化合物 R75R76R77R78m.p.(℃)序号3.064CH3(CH2)3CF3CF2CH3H3.065PhCF3CF2CH3H3.066CH2Br CF3CF2CH3H3.067CH2OCH3CF3CF2CH3H3.068CH2SMe CF3CF2CH3H3.069CH2SO2Me CF3CF2CH3H3.070SCH3CF3CF2CH3H3.071SOCH3CF3CF2CH3H3.072SO2CH3CF3CF2CH3H3.073SPh CF3CF2CH3H3.074SOPh CF3CF2CH3H3.075SO2Ph CF3CF2CH3H3.076CH3CHF2CH3H3.077CH3CH2CHF2CH3H3.078(CH3)2CH CHF2CH3H3.079CH3(CH2)3CHF2CH3H3.080Ph CHF2CH3H3.081CH2Br CHF2CH3H3.082CH2OCH3CHF2CH3H3.083CH2SMe CHF2CH3H3.084CH2SO2Me CHF2CH3H3.085SCH3CHF2CH3H3.086SOCH3CHF2CH3H3.087SO2CH3CHF2CH3H3.088SPh CHF2CH3H3.089SOPh CHF2CH3H3.090SO2Ph CHF2CH3H3.091CH3CF3H CH33.092CH3CH2CF3H CH33.093(CH3)2CH CF3H CH33.094CH3(CH2)3CF3H CH33.095PhCF3H CH3化合物 R75R76R77R78m.p.(℃)序号3.096 CH2Br CF3H CH33.097 CH2OCH3CF3H CH33.098 CH2SMe CF3H CH33.099 CH2SO2Me CF3H CH33.100 SCH3CF3H CH33.101 SOCH3CF3H CH33.102 SO2CH3CF3H CH33.103 SPh CF3H CH33.104 SOPhCF3H CH33.105 SO2Ph CF3H CH3表4式Ie化合物 化合物 R75R76R77R78Z m.p.(℃)序号4.001 CH3CF3H H S 103-1044.002 CH3CH2CF3H H S4.003 (CH3)2CH CF3H H S4.004 CH3(CH2)3CF3H H S4.005 PhCF3H H S4.006 CH2Br CF3H H S4.007 CH2OCH3CF3H H S4.008 CH2SMe CF3H H S化合物 R75R76R77R78Z m.p.(℃)序号4.009CH2SO2Me CF3H H S4.010SCH3CF3H H S4.011SOCH3CF3H H S4.012SO2CH3CF3H H S4.013SPh CF3H H S4.014SOPh CF3H H S4.015SO2Ph CF3H H S4.016CH3CF3CF2H H S4.017CH3CH2CF3CF2H H S4.018(CH3)2CH CF3CF2H H S4.019CH3(CH2)3CF3CF2H H S4.020PhCF3CF2H H S4.021CH2Br CF3CF2H H S4.022CH2OCH3CF3CF2H H S4.023CH2SMe CF3CF2H H S4.024CH2SO2Me CF3CF2H H S4.025SCH3CF3CF2H H S4.026SOCH3CF3CF2H H S4.027SO2CH3CF3CF2H H S4.028SPh CF3CF2H H S4.029SOPh CF3CF2H H S4.030SO2Ph CF3CF2H H S4.031CH3CHF2H H S4.032CH3CH2CHF2H H S4.033(CH3)2CH CHF2H H S4.034CH3(CH2)3CHF2H H S4.035PhCHF2H H S4.036CH2Br CHF2H H S4.037CH2OCH3CHF2H H S4.038CH2SMe CHF2H H S4.039CH2SO2Me CHF2H H S4.040SCH3CHF2H H S化合物R75R76R77R78Z m.p.(℃)序号4.041 SOCH3CHF2H H S4.042 SO2CH3CHF2H H S4.043 SPh CHF2H H S4.044 SOPh CHF2H H S4.045 SO2PhCHF2H H S4.046 CH3CF3CH3H S4.047 CH3CH2CF3CH3H S4.048 (CH3)2CHCF3CH3H S4.049 CH3(CH2)3CF3CH3H S4.050 PhCF3CH3H S4.051 CH2BrCF3CH3H S4.052 CH2OCH3CF3CH3H S4.053 CH2SMe CF3CH3H S4.054 CH2SO2MeCF3CH3H S4.055 SCH3CF3CH3H S4.056 SOCH3CF3CH3H S4.057 SO2CH3CF3CH3H S4.058 SPh CF3CH3H S4.059 SOPh CF3CH3H S4.060 SO2PhCF3CH3H S4.061 CH3CF3CF2CH3H S4.062 CH3CH2CF3CF2CH3H S4.063 (CH3)2CHCF3CF2CH3H S4.064 CH3(CH2)3CF3CF2CH3H S4.065 PhCF3CF2CH3H S4.066 CH2BrCF3CF2CH3H S4.067 CH2OCH3CF3CF2CH3H S4.068 CH2SMe CF3CF2CH3H S4.069 CH2SO2MeCF3CF2CH3H S4.070 SCH3CF3CF2CH3H S4.071 SOCH3CF3CF2CH3H S4.072 SO2CH3CF3CF2CH3H S化合物R75R76R77R78Z m.p.(℃)序号4.073 SPh CF3CF2CH3HS4.074 SOPh CF3CF2CH3HS4.075 SO2PhCF3CF2CH3HS4.076 CH3CHF2CH3HS4.077 CH3CH2CHF2CH3HS4.078 (CH3)2CHCHF2CH3HS4.079 CH3(CH2)3CHF2CH3HS4.080 PhCHF2CH3HS4.081 CH2BrCHF2CH3HS4.082 CH2OCH3CHF2CH3HS4.083 CH2SMe CHF2CH3HS4.084 CH2SO2MeCHF2CH3HS4.085 SCH3CHF2CH3HS4.086 SOCH3CHF2CH3HS4.087 SO2CH3CHF2CH3HS4.088 SPh CHF2CH3HS4.089 SOPh CHF2CH3HS4.090 SO2PhCHF2CH3HS4.091 CH3CF3H CH3S4.092 CH3CH2CF3H CH3S4.093 (CH3)2CHCF3H CH3S4.094 CH3(CH2)3CF3H CH3S4.095 PhCF3H CH3S4.096 CH2BrCF3H CH3S4.097 CH2OCH3CF3H CH3S4.098 CH2SMe CF3H CH3S4.099 CH2SO2MeCF3H CH3S4.100 SCH3CF3H CH3S4.101 SOCH3CF3H CH3S4.102 SO2CH3CF3H CH3S4.103 SPh CF3H CH3S4.104 SOPh CF3H CH3S化合物. R75R76R77R78Z m.p.(℃)序号4.105 SO2PhCF3HCH3S4.106 CH3CF3HH SO 96-974.107 CH3CH2CF3HH SO4.108 (CH3)2CHCF3HH SO4.109 CH3(CH2)3CF3HH SO4.110 PhCF3HH SO4.111 CH2BrCF3HH SO4.112 CH2OCH3CF3HH SO4.113 CH2SMe CF3HH SO4.114 CH2SO2MeCF3HH SO4.115 SCH3CF3HH SO4.116 SOCH3CF3HH SO4.117 SO2CH3CF3HH SO4.118 SPh CF3HH SO4.119 SOPh CF3HH SO4.120 SO2PhCF3HH SO4.121 CH3CF3CF2HH SO4.122 CH3CH2CF3CF2HH SO4.123 (CH3)2CHCF3CF2HH SO4.124 CH3(CH2)3CF3CF2HH SO4.125 PhCF3CF2HH SO4.126 CH2BrCF3CF2HH SO4.127 CH2OCH3CF3CF2HH SO4.128 CH2SMe CF3CF2HH SO4.129 CH2SO2MeCF3CF2HH SO4.130 SCH3CF3CF2HH SO4.131 SOCH3CF3CF2HH SO4.132 SO2CH3CF3CF2HH SO4.133 SPh CF3CF2HH SO4.134 SOPh CF3CF2HH SO4.135 SO2PhCF3CF2HH SO4.136 CH3CHF2HH SO化合物R75R76R77R78Z m.p.(℃)序号4.137 CH3CH2CHF2H H SO4.138 (CH3)2CHCHF2H H SO4.139 CH3(CH2)3CHF2H H SO4.140 PhCHF2H H SO4.141 CH2BrCHF2H H SO4.142 CH2OCH3CHF2H H SO4.143 CH2SMe CHF2H H SO4.144 CH2SO2MeCHF2H H SO4.145 SCH3CHF2H H SO4.146 SOCH3CHF2H H SO4.147 SO2CH3CHF2H H SO4.148 SPh CHF2H H SO4.149 SOPh CHF2H H SO4.150 SO2PhCHF2H H SO4.151 CH3CF3CH3H SO4.152 CH3CH2CF3CH3H SO4.153 (CH3)2CHCF3CH3H SO4.154 CH3(CH2)3CF3CH3H SO4.155 PhCF3CH3H SO4.156 CH2BrCF3CH3H SO4.157 CH2OCH3CF3CH3H SO4.158 CH2SMe CF3CH3H SO4.159 CH2SO2MeCF3CH3H SO4.160 SCH3CF3CH3H SO4.161 SOCH3CF3CH3H SO4.162 SO2CH3CF3CH3H SO4.163 SPh CF3CH3H SO4.164 SOPh CF3CH3H SO4.165 SO2PhCF3CH3H SO4.166 CH3CF3CF2CH3H SO4.167 CH3CH2CF3CF2CH3H SO4.168 (CH3)2CHCF3CF2CH3H SO化合物 R75R76R77R78Z m.p.(℃)序号4.169CH3(CH2)3CF3CF2CH3H SO4.170PhCF3CF2CH3H SO4.171CH2BrCF3CF2CH3H SO4.172CH2OCH3CF3CF2CH3H SO4.173CH2SMe CF3CF2CH3H SO4.174CH2SO2MeCF3CF2CH3H SO4.175SCH3CF3CF2CH3H SO4.176SOCH3CF3CF2CH3H SO4.177SO2CH3CF3CF2CH3H SO4.178SPh CF3CF2CH3H SO4.179SOPh CF3CF2CH3H SO4.180SO2PhCF3CF2CH3H SO4.181CH3CHF2CH3H SO4.182CH3CH2CHF2CH3H SO4.183(CH3)2CHCHF2CH3H SO4.184CH3(CH2)3CHF2CH3H SO4.185PhCHF2CH3H SO4.186CH2BrCHF2CH3H SO4.187CH2OCH3CHF2CH3H SO4.188CH2SMe CHF2CH3H SO4.189CH2SO2MeCHF2CH3H SO4.190SCH3CHF2CH3H SO4.191SOCH3CHF2CH3H SO4.192SO2CH3CHF2CH3H SO4.193SPh CHF2CH3H SO4.194SOPh CHF2CH3H SO4.195SO2PhCHF2CH3H SO4.196CH3CF3H CH3SO4.197CH3CH2CF3H CH3SO4.198(CH3)2CHCF3H CH3SO4.199CH3(CH2)3CF3H CH3SO4.200PhCF3H CH3SO化合物 R75R76R77R78Z m.p.(℃)序号4.201 CH2BrCF3H CH3SO4.202 CH2OCH3CF3H CH3SO4.203 CH2SMe CF3H CH3SO4.204 CH2SO2MeCF3H CH3SO4.205 SCH3CF3H CH3SO4.206 SOCH3CF3H CH3SO4.207 SO2CH3CF3H CH3SO4.208 SPh CF3H CH3SO4.209 SOPh CF3H CH3SO4.210 SO2PhCF3H CH3SO4.211 CH3CF3H H SO2无定形4.212 CH3CH2CF3H H SO24.213 (CH3)2CHCF3H H SO24.214 CH3(CH2)3CF3H H SO24.215 PhCF3H H SO24.216 CH2BrCF3H H SO24.217 CH2OCH3CF3H H SO24.218 CH2SMe CF3H H SO24.219 CH2SO2MeCF3H H SO24.220 SCH3CF3H H SO24.221 SOCH3CF3H H SO24.222 SO2CH3CF3H H SO24.223 SPh CF3H H SO24.224 SOPh CF3H H SO24.225 SO2PhCF3H H SO24.226 CH3CF3CF2H H SO24.227 CH3CH2CF3CF2H H SO24.228 (CH3)2CHCF3CF2H H SO24.229 CH3(CH2)3CF3CF2H H SO24.230 PhCF3CF2H H SO24.231 CH2BrCF3CF2H H SO2化合物R75R76R77R78Zm.p.(℃)序号4.232 CH2OCH3CF3CF2H H SO24.233 CH2SMe CF3CF2H H SO24.234 CH2SO2MeCF3CF2H H SO24.235 SCH3CF3CF2H H SO24.236 SOCH3CF3CF2H H SO24.237 SO2CH3CF3CF2H H SO24.238 SPh CF3CF2H H SO24.239 SOPh CF3CF2H H SO24.240 SO2PhCF3CF2H H SO24.241 CH3CHF2H H SO24.242 CH3CH2CHF2H H SO24.243 (CH3)2CHCHF2H H SO24.244 CH3(CH2)3CHF2H H SO24.245 PhCHF2H H SO24.246 CH2BrCHF2H H SO24.247 CH2OCH3CHF2H H SO24.248 CH2SMe CHF2H H SO24.249 CH2SO2MeCHF2H H SO24.250 SCH3CHF2H H SO24.251 SOCH3CHF2H H SO24.252 SO2CH3CHF2H H SO24.253 SPh CHF2H H SO24.254 SOPh CHF2H H SO24.255 SO2PhCHF2H H SO24.256 CH3CF3CH3H SO24.257 CH3CH2CF3CH3H SO24.258 (CH3)2CHCF3CH3H SO24.259 CH3(CH2)3CF3CH3H SO24.260 PhCF3CH3H SO24.261 CH2BrCF3CH3H SO24.262 CH2OCH3CF3CH3H SO24.263 CH2SMe CF3CH3H SO2化合物R75R76R77R78Z m.p.(℃)序号4.264 CH2SO2Me CF3CH3H SO24.265 SCH3CF3CH3H SO24.266 SOCH3CF3CH3H SO24.267 SO2CH3CF3CH3H SO24.268 SPhCF3CH3H SO24.269 SOPh CF3CH3H SO24.270 SO2Ph CF3CH3H SO24.271 CH3CF3CF2CH3H SO24.272 CH3CH2CF3CF2CH3H SO24.273 (CH3)2CH CF3CF2CH3H SO24.274 CH3(CH2)3CF3CF2CH3H SO24.275 Ph CF3CF2CH3H SO24.276 CH2Br CF3CF2CH3H SO24.277 CH2OCH3CF3CF2CH3H SO24.278 CH2SMeCF3CF2CH3H SO24.279 CH2SO2Me CF3CF2CH3H SO24.280 SCH3CF3CF2CH3H SO24.281 SOCH3CF3CF2CH3H SO24.282 SO2CH3CF3CF2CH3H SO24.283 SPhCF3CF2CH3H SO24.284 SOPh CF3CF2CH3H SO24.285 SO2Ph CF3CF2CH3H SO24.286 CH3CHF2CH3H SO24.287 CH3CH2CHF2CH3H SO24.288 (CH3)2CH CHF2CH3H SO24.289 CH3(CH2)3CHF2CH3H SO24.290 Ph CHF2CH3H SO24.291 CH2Br CHF2CH3H SO24.292 CH2OCH3CHF2CH3H SO24.293 CH2SMeCHF2CH3H SO24.294 CH2SO2Me CHF2CH3H SO24.295 SCH3CHF2CH3H SO2化合物 R75R76R77R78Z m.p.(℃)序号4.296 SOCH3CHF2CH3HSO24.297 SO2CH3CHF2CH3HSO24.298 SPh CHF2CH3HSO24.299 SOPh CHF2CH3HSO24.300 SO2PhCHF2CH3HSO24.301 CH3CF3H CH3SO24.302 CH3CH2CF3H CH3SO24.303 (CH3)2CHCF3H CH3SO24.304 CH3(CH2)3CF3H CH3SO24.305 PhCF3H CH3SO24.306 CH2BrCF3H CH3SO24.307 CH2OCH3CF3H CH3SO24.308 CH2SMe CF3H CH3SO24.309 CH2SO2MeCF3H CH3SO24.310 SCH3CF3H CH3SO24.311 SOCH3CF3H CH3SO24.312 SO2CH3CF3H CH3SO24.313 SPh CF3H CH3SO24.314 SOPh CF3H CH3SO24.315 SO2PhCF3H CH3SO2表5式XVI化合物 化合物 R79R80R81R82序号A1 H H H CF3化合物.R79R80R81R82序号A2 CH3H H CF3A3 CH3CH2H H CF3A4 (CH3)2CH H H CF3A5 (CH3)3C H H CF3A6 环丙基 H H CF3A7 CH3(CH2)2H H CF3A8 CH3OCH2H H CF3A9 CH3O(CH2)2H H CF3A10Ph H H CF3A11PhO H H CF3A12PhS H H CF3A13PhSOH H CF3A14PhSO2H H CF3A15CH3S H H CF3A16CH3SO H H CF3A17CF3H H CF3A18F2CH H H CF3A19HCC H H CF3A20CH3CC H H CF3A21CH2＝CHH H CF3A22CH2＝CHCH2H H CF3A23CH3SO2N(CH3)H H CF3A24(CH3)2N H H CF3A25(CH3)2NSO2H H CF3A26ClCH2H H CF3A27CH3SCH2H H CF3A28CH3SOCH2H H CF3A29CH3SO2CH2H H CF3A30[1，2，4]-三唑-1-基-甲基H H CF3A31CH3CF3H CH3A32CH3CH3H CF3A33H H H CF3CF2化合物 R79R80R81R82序号A34 CH3HH CF3CF2A35 CH3CH2HH CF3CF2A36 环丙基 HH CF3CF2A37 (CH3)3C HH CF3CF2A38 (CH3)2CH HH CF3CF2A39 CH3(CH2)2HH CF3CF2A40 CH3OCH2HH CF3CF2A41 CH3O(CH2)2HH CF3CF2A42 Ph HH CF3CF2A43 PhO HH CF3CF2A44 PhS HH CF3CF2A45 PhSOHH CF3CF2A46 PhSO2HH CF3CF2A47 CH3S HH CF3CF2A48 CH3SO HH CF3CF2A49 CF3HH CF3CF2A50 F2CH HH CF3CF2A51 HCC HH CF3CF2A52 CH3CC HH CF3CF2A53 CH2＝CHHH CF3CF2A54 CH2＝CHCH2HH CF3CF2A55 CH3SO2N(CH3)HH CF3CF2A56 (CH3)2N HH CF3CF2A57 (CH3)2NSO2HH CF3CF2A58 ClCH2HH CF3CF2A59 CH3SCH2HH CF3CF2A60 CH3SOCH2HH CF3CF2A61 CH3SO2CH2HH CF3CF2A62 [1，2，4]-三唑-1-基-甲基HH CF3CF2A63 H HH CF3CF2CF2A64 CH3HH CF3CF2CF2A65 CH3CH2HH CF3CF2CF2化合物. R79R80R81R82序号A66 环丙基 HH CF3CF2CF2A67 (CH3)3C HH CF3CF2CF2A68 (CH3)2CH HH CF3CF2CF2A69 CH3(CH2)2HH CF3CF2CF2A70 CH3OCH2HH CF3CF2CF2A71 CH3O(CH2)2HH CF3CF2CF2A72 Ph HH CF3CF2CF2A73 PhO HH CF3CF2CF2A74 PhS HH CF3CF2CF2A75 PhSOHH CF3CF2CF2A76 PhSO2HH CF3CF2CF2A77 CH3S HH CF3CF2CF2A78 CH3SO HH CF3CF2CF2A79 CF3HH CF3CF2CF2A80 F2CH HH CF3CF2CF2A81 HCC HH CF3CF2CF2A82 CH3CC HH CF3CF2CF2A83 CH2＝CHHH CF3CF2CF2A84 CH2＝CHCH2HH CF3CF2CF2A85 CH3SO2N(CH3)HH CF3CF2CF2A86 (CH3)2N HH CF3CF2CF2A87 (CH3)2NSO2HH CF3CF2CF2A88 ClCH2HH CF3CF2CF2A89 CH3SCH2HH CF3CF2CF2A90 CH3SOCH2HH CF3CF2CF2A91 CH3SO2CH2HH CF3CF2CF2A92 [1，2，4]-三唑-1-基-甲基HH CF3CF2CF2A93 H HH CF2ClA94 CH3HH CF2ClA95 CH3CH2HH CF2ClA96 环丙基 HH CF2ClA97 (CH3)3C HH CF2Cl化合物R79R80R81R82序号A98 (CH3)2CH H H CF2ClA99 CH3(CH2)2H H CF2ClA100 CH3OCH2H H CF2ClA101 CH3O(CH2)2H H CF2ClA102 Ph H H CF2ClA103 PhO H H CF2ClA104 PhS H H CF2ClA105 PhSOH H CF2ClA106 PhSO2H H CF2ClA107 CH3S H H CF2ClA108 CH3SO H H CF2ClA109 CF3H H CF2ClA110 F2CH H H CF2ClA111 HCC H H CF2ClA112 CH3CC H H CF2ClA113 CH2＝CHH H CF2ClA114 CH2＝CHCH2H H CF2ClA115 CH3SO2N(CH3)H H CF2ClA116 (CH3)2N H H CF2ClA117 (CH3)2NSO2H H CF2ClA118 ClCH2H H CF2ClA119 CH3SCH2H H CF2ClA120 CH3SOCH2H H CF2ClA121 CH3SO2CH2H H CF2ClA122 [1，2，4]-三唑-1-基-甲基H H CF2ClA123 H H H CHF2A124 CH3H H CHF2A125 CH3CH2H H CHF2A126 环丙基 H H CHF2A127 (CH3)3C H H CHF2A128 (CH3)2CH H H CHF2A129 CH3(CH2)2H H CHF2化合物 R79R80R81R82序号A130 CH3OCH2H H CHF2A131 CH3O(CH2)2H H CHF2A132 Ph H H CHF2A133 PhO H H CHF2A134 PhS H H CHF2A135 PhSOH H CHF2A136 PhSO2H H CHF2A137 CH3S H H CHF2A138 CH3SO H H CHF2A139 CF3H H CHF2A140 F2CH H H CHF2A141 HCC H H CHF2A142 CH3CC H H CHF2A143 CH2＝CHH H CHF2A144 CH2＝CHCH2H H CHF2A145 CH3SO2N(CH3)H H CHF2A146 (CH3)2N H H CHF2A147 (CH3)2NSO2H H CHF2A148 ClCH2H H CHF2A149 CH3SCH2H H CHF2A150 CH3SOCH2H H CHF2A151 CH3SO2CH2H H CHF2A152 [1，2，4]-三唑-1-基-甲基H H CHF2A153 H H H CCl3A154 CH3H H CCl3A155 CH3CH2H H CCl3A156 环丙基 H H CCl3A157 (CH3)3C H H CCl3A158 (CH3)2CH H H CCl3A159 CH3(CH2)2H H CCl3A160 CH3OCH2H H CCl3A161 CH3O(CH2)2H H CCl3化合物 R79R80R81R82序号A162 Ph H HCCl3A163 PhO H HCCl3A164 PhS H HCCl3A165 PhSOH HCCl3A166 PhSO2H HCCl3A167 CH3S H HCCl3A168 CH3SO H HCCl3A169 CF3H HCCl3A170 F2CH H HCCl3A171 HCC H HCCl3A172 CH3CC H HCCl3A173 CH2＝CHH HCCl3A174 CH2＝CHCH2H HCCl3A175 CH3SO2N(CH3)H HCCl3A176 (CH3)2N H HCCl3A177 (CH3)2NSO2H HCCl3A178 ClCH2H HCCl3A179 CH3SCH2H HCCl3A180 CH3SOCH2H HCCl3A181 CH3SO2CH2H HCCl3A182 [1，2，4]-三唑-1-基-甲基H HCCl3A183 H H CH3CF3A184 CH3H CH3CF3A185 CH3CH2H CH3CF3A186 环丙基 H CH3CF3A187 (CH3)3C H CH3CF3A188 (CH3)2CH H CH3CF3A189 CH3(CH2)2H CH3CF3A190 CH3OCH2H CH3CF3A191 CH3O(CH2)2H CH3CF3A192 Ph H CH3CF3A193 PhO H CH3CF3化合物 R79R80R81R82序号A194PhS H CH3CF3A195PhSO H CH3CF3A196PhSO2H CH3CF3A197CH3SH CH3CF3A198CH3SO H CH3CF3A199CF3H CH3CF3A200F2CHH CH3CF3A201HCC H CH3CF3A202CH3CC H CH3CF3A203CH2＝CH H CH3CF3A204CH2＝CHCH2H CH3CF3A205CH3SO2N(CH3) H CH3CF3A206(CH3)2N H CH3CF3A207(CH3)2NSO2H CH3CF3A208ClCH2H CH3CF3A209CH3SCH2H CH3CF3A210CH3SOCH2H CH3CF3A211CH3SO2CH2H CH3CF3A212HH CH3CF3CF2A213CH3H CH3CF3CF2A214CH3CH2H CH3CF3CF2A215环丙基 H CH3CF3CF2A216(CH3)3C H CH3CF3CF2A217(CH3)2CH H CH3CF3CF2A218CH3(CH2)2H CH3CF3CF2A219CH3OCH2H CH3CF3CF2A220CH3O(CH2)2H CH3CF3CF2A221Ph H CH3CF3CF2A222PhO H CH3CF3CF2A223PhS H CH3CF3CF2A224PhSO H CH3CF3CF2A225PhSO2H CH3CF3CF2化合物 R79R80R81R82序号A226 CH3S H CH3CF3CF2A227 CH3SO H CH3CF3CF2A228 CF3H CH3CF3CF2A229 F2CH H CH3CF3CF2A230 HCC H CH3CF3CF2A231 CH3CC H CH3CF3CF2A232 CH2＝CHH CH3CF3CF2A233 CH2＝CHCH2H CH3CF3CF2A234 CH3SO2N(CH3)H CH3CF3CF2A235 (CH3)2N H CH3CF3CF2A236 (CH3)2NSO2H CH3CF3CF2A237 ClCH2H CH3CF3CF2A238 CH3SCH2H CH3CF3CF2A239 CH3SOCH2H CH3CF3CF2A240 CH3SO2CH2H CH3CF3CF2A241 H H CH3CF3CF2CF2A242 CH3H CH3CF3CF2CF2A243 CH3CH2H CH3CF3CF2CF2A244 环丙基 H CH3CF3CF2CF2A245 (CH3)3C H CH3CF3CF2CF2A246 (CH3)2CH H CH3CF3CF2CF2A247 CH3(CH2)2H CH3CF3CF2CF2A248 CH3OCH2H CH3CF3CF2CF2A249 CH3O(CH2)2H CH3CF3CF2CF2A250 Ph H CH3CF3CF2CF2A251 PhO H CH3CF3CF2CF2A252 PhS H CH3CF3CF2CF2A253 PhSOH CH3CF3CF2CF2A254 PhSO2H CH3CF3CF2CF2A255 CH3S H CH3CF3CF2CF2A256 CH3SO H CH3CF3CF2CF2A257 CF3H CH3CF3CF2CF2化合物 R79R80R81R82序号A258 F2CH H CH3CF3CF2CF2A259 HCCH CH3CF3CF2CF2A260 CH3CC H CH3CF3CF2CF2A261 CH2＝CH H CH3CF3CF2CF2A262 CH2＝CHCH2H CH3CF3CF2CF2A263 CH3SO2N(CH3) H CH3CF3CF2CF2A264 (CH3)2N H CH3CF3CF2CF2A265 (CH3)2NSO2H CH3CF3CF2CF2A266 ClCH2H CH3CF3CF2CF2A267 CH3SCH2H CH3CF3CF2CF2A268 CH3SOCH2H CH3CF3CF2CF2A269 CH3SO2CH2H CH3CF3CF2CF2A270 H H CH3CF2ClA271 CH3H CH3CF2ClA272 CH3CH2H CH3CF2ClA273 环丙基 H CH3CF2ClA274 (CH3)3C H CH3CF2ClA275 (CH3)2CHH CH3CF2ClA276 CH3(CH2)2H CH3CF2ClA277 CH3OCH2H CH3CF2ClA278 CH3O(CH2)2H CH3CF2ClA279 Ph H CH3CF2ClA280 PhOH CH3CF2ClA281 PhSH CH3CF2ClA282 PhSO H CH3CF2ClA283 PhSO2H CH3CF2ClA284 CH3S H CH3CF2ClA285 CH3SO H CH3CF2ClA286 CF3H CH3CF2ClA287 F2CH H CH3CF2ClA288 HCCH CH3CF2ClA289 CH3CC H CH3CF2Cl化合物 R79R80R81R82序号A290 CH2＝CH H CH3CF2ClA291 CH2＝CHCH2H CH3CF2ClA292 CH3SO2N(CH3) H CH3CF2ClA293 (CH3)2N H CH3CF2ClA294 (CH3)2NSO2H CH3CF2ClA295 ClCH2H CH3CF2ClA296 CH3SCH2H CH3CF2ClA297 CH3SOCH2H CH3CF2ClA298 CH3SO2CH2H CH3CF2ClA299 H H CH3CHF2A300 CH3H CH3CHF2A301 CH3CH2H CH3CHF2A302 环丙基 H CH3CHF2A303 (CH3)3C H CH3CHF2A304 (CH3)2CHH CH3CHF2A305 CH3(CH2)2H CH3CHF2A306 CH3OCH2H CH3CHF2A307 CH3O(CH2)2H CH3CHF2A308 Ph H CH3CHF2A309 PhOH CH3CHF2A310 PhSH CH3CHF2A311 PhSO H CH3CHF2A312 PhSO2H CH3CHF2A313 CH3S H CH3CHF2A314 CH3SO H CH3CHF2A315 CF3H CH3CHF2A316 F2CH H CH3CHF2A317 HCCH CH3CHF2A318 CH3CC H CH3CHF2A319 CH2＝CH H CH3CHF2A320 CH2＝CHCH2H CH3CHF2A321 CH3SO2N(CH3) H CH3CHF2化合物 R79R80R81R82序号A322 (CH3)2N H CH3CHF2A323 (CH3)2NSO2H CH3CHF2A324 ClCH2H CH3CHF2A325 CH3SCH2H CH3CHF2A326 CH3SOCH2H CH3CHF2A327 CH3SO2CH2H CH3CHF2A328 HH CH3CCl3A329 CH3H CH3CCl3A330 CH3CH2H CH3CCl3A331 (CH3)3C H CH3CCl3A332 (CH3)2CH H CH3CCl3A333 环丙基 H CH3CCl3A334 CH3(CH2)2H CH3CCl3A335 CH3OCH2H CH3CCl3A336 CH3O(CH2)2H CH3CCl3A337 Ph H CH3CCl3A338 PhO H CH3CCl3A339 PhS H CH3CCl3A340 PhSO H CH3CCl3A341 PhSO2H CH3CCl3A342 CH3SH CH3CCl3A343 CH3SO H CH3CCl3A344 CF3H CH3CCl3A345 F2CHH CH3CCl3A346 HCC H CH3CCl3A347 CH3CC H CH3CCl3A348 CH2＝CH H CH3CCl3A349 CH2＝CHCH2H CH3CCl3A350 CH3SO2N(CH3) H CH3CCl3A351 (CH3)2N H CH3CCl3A352 (CH3)2NSO2H CH3CCl3A353 ClCH2H CH3CCl3化合物 R79R80R81R82序号A354 CH3SCH2H CH3CCl3A355 CH3SOCH2H CH3CCl3A356 CH3SO2CH2H CH3CCl3A357 H H Ph CF3A358 CH3H Ph CF3A359 CH3CH2H Ph CF3A360 环丙基 H Ph CF3A361 (CH3)3C H Ph CF3A362 (CH3)2CHH Ph CF3A363 CH3(CH2)2H Ph CF3A364 CH3OCH2H Ph CF3A365 CH3O(CH2)2H Ph CF3A366 Ph H Ph CF3A367 PhOH Ph CF3A368 PhSH Ph CF3A369 PhSO H Ph CF3A370 PhSO2H Ph CF3A371 CH3S H Ph CF3A372 CH3SO H Ph CF3A373 CF3H Ph CF3A374 F2CH H Ph CF3A375 HCCH Ph CF3A376 CH3CC H Ph CF3A377 CH2＝CH H Ph CF3A378 CH2＝CHCH2H Ph CF3A379 CH3SO2N(CH3) H Ph CF3A380 (CH3)2N H Ph CF3A381 (CH3)2NSO2H Ph CF3A382 ClCH2H Ph CF3A383 CH3SCH2H Ph CF3A384 CH3SOCH2H Ph CF3A385 CH3SO2CH2H Ph CF3化合物R79R80R81R82序号A386 H H Ph CF3CF2A387 CH3H Ph CF3CF2A388 CH3CH2H Ph CF3CF2A389 环丙基H Ph CF3CF2A390 (CH3)3CH Ph CF3CF2A391 (CH3)2CH H Ph CF3CF2A392 CH3(CH2)2H Ph CF3CF2A393 CH3OCH2H Ph CF3CF2A394 CH3O(CH2)2H Ph CF3CF2A395 PhH Ph CF3CF2A396 PhO H Ph CF3CF2A397 PhS H Ph CF3CF2A398 PhSO H Ph CF3CF2A399 PhSO2H Ph CF3CF2A400 CH3S H Ph CF3CF2A401 CH3SOH Ph CF3CF2A402 CF3H Ph CF3CF2A403 F2CH H Ph CF3CF2A404 HCC H Ph CF3CF2A405 CH3CCH Ph CF3CF2A406 CH2＝CH H Ph CF3CF2A407 CH2＝CHCH2H Ph CF3CF2A408 CH3SO2N(CH3) H Ph CF3CF2A409 (CH3)2NH Ph CF3CF2A410 (CH3)2NSO2H Ph CF3CF2A411 ClCH2H Ph CF3CF2A412 CH3SCH2H Ph CF3CF2A413 CH3SOCH2H Ph CF3CF2A414 CH3SO2CH2H Ph CF3CF2A415 H H Ph CF3CF2CF2A416 CH3H Ph CF3CF2CF2A417 CH3CH2H Ph CF3CF2CF2化合物. R79R80R81R82序号A418 环丙基 H Ph CF3CF2CF2A419 (CH3)3C H Ph CF3CF2CF2A420 (CH3)2CH H Ph CF3CF2CF2A421 CH3(CH2)2H Ph CF3CF2CF2A422 CH3OCH2H Ph CF3CF2CF2A423 CH3O(CH2)2H Ph CF3CF2CF2A424 Ph H Ph CF3CF2CF2A425 PhO H Ph CF3CF2CF2A426 PhS H Ph CF3CF2CF2A427 PhSO H Ph CF3CF2CF2A428 PhSO2H Ph CF3CF2CF2A429 CH3SH Ph CF3CF2CF2A430 CH3SO H Ph CF3CF2CF2A431 CF3H Ph CF3CF2CF2A432 F2CHH Ph CF3CF2CF2A433 HCC H Ph CF3CF2CF2A434 CH3CC H Ph CF3CF2CF2A435 CH2＝CH H Ph CF3CF2CF2A436 CH2＝CHCH2H Ph CF3CF2CF2A437 CH3SO2N(CH3) H Ph CF3CF2CF2A438 (CH3)2N H Ph CF3CF2CF2A439 (CH3)2NSO2H Ph CF3CF2CF2A440 ClCH2H Ph CF3CF2CF2A441 CH3SCH2H Ph CF3CF2CF2A442 CH3SOCH2H Ph CF3CF2CF2A443 CH3SO2CH2H Ph CF3CF2CF2A444 HH Ph CF2ClA445 CH3H Ph CF2ClA446 CH3CH2H Ph CF2ClA447 cyclopropyl H Ph CF2ClA448 (CH3)3C H Ph CF2ClA449 (CH3)2CH H Ph CF2Cl化合物R79R80R81R82序号A450 CH3(CH2)2H Ph CF2ClA451 CH3OCH2H Ph CF2ClA452 CH3O(CH2)2H Ph CF2ClA453 Ph H Ph CF2ClA454 PhOH Ph CF2ClA455 PhSH Ph CF2ClA456 PhSO H Ph CF2ClA457 PhSO2H Ph CF2ClA458 CH3S H Ph CF2ClA459 CH3SO H Ph CF2ClA460 CF3H Ph CF2ClA461 F2CH H Ph CF2ClA462 HCCH Ph CF2ClA463 CH3CC H Ph CF2ClA464 CH2＝CH H Ph CF2ClA465 CH2＝CHCH2H Ph CF2ClA466 CH3SO2N(CH3) H Ph CF2ClA467 (CH3)2N H Ph CF2ClA468 (CH3)2NSO2H Ph CF2ClA469 ClCH2H Ph CF2ClA470 CH3SCH2H Ph CF2ClA471 CH3SOCH2H Ph CF2ClA472 CH3SO2CH2H Ph CF2ClA473 H H Ph CHF2A474 CH3H Ph CHF2A475 CH3CH2H Ph CHF2A476 环丙基 H Ph CHF2A477 (CH3)3C H Ph CHF2A478 (CH3)2CH H Ph CHF2A479 CH3(CH2)2H Ph CHF2A480 CH3OCH2H Ph CHF2A481 CH3O(CH2)2H Ph CHF2化合物R79R80R81R82序号A482 Ph H Ph CHF2A483 PhO H Ph CHF2A484 PhS H Ph CHF2A485 PhSOH Ph CHF2A486 PhSO2H Ph CHF2A487 CH3S H Ph CHF2A488 CH3SO H Ph CHF2A489 CF3H Ph CHF2A490 F2CH H Ph CHF2A491 HCC H Ph CHF2A492 CH3CC H Ph CHF2A493 CH2＝CHH Ph CHF2A494 CH2＝CHCH2H Ph CHF2A495 CH3SO2N(CH3)H Ph CHF2A496 (CH3)2N H Ph CHF2A497 (CH3)2NSO2H Ph CHF2A498 ClCH2H Ph CHF2A499 CH3SCH2H Ph CHF2A500 CH3SOCH2H Ph CHF2A501 CH3SO2CH2H Ph CHF2A502 H H Ph CCl3A503 CH3H Ph CCl3A504 CH3CH2H Ph CCl3A505 环丙基 H Ph CCl3A506 (CH3)3C H Ph CCl3A507 (CH3)2CH H Ph CCl3A508 CH3(CH2)2H Ph CCl3A509 CH3OCH2H Ph CCl3A510 CH3O(CH2)2H Ph CCl3A511 Ph H Ph CCl3A512 PhO H Ph CCl3A513 PhS H Ph CCl3化合物R79R80R81R82序号A514 PhSO H Ph CCl3A515 PhSO2H Ph CCl3A516 CH3SH Ph CCl3A517 CH3SO H Ph CCl3A518 CF3H Ph CCl3A519 F2CHH Ph CCl3A520 HCC H Ph CCl3A521 CH3CC H Ph CCl3A522 CH2＝CH H Ph CCl3A523 CH2＝CHCH2H Ph CCl3A524 CH3SO2N(CH3) H Ph CCl3A525 (CH3)2N H Ph CCl3A526 (CH3)2NSO2H Ph CCl3A527 ClCH2H Ph CCl3A528 CH3SCH2H Ph CCl3A529 CH3SOCH2H Ph CCl3A530 CH3SO2CH2H Ph CCl3A531 HCH3H CF3A532 HCH3CH2H CF3A533 H环丙基 H CF3A534 H(CH3)3CH H CF3A535 H(CH3)2CH H CF3A536 HCH3(CH2)2H CF3A537 HCH3OCH2H CF3A538 HCH3O(CH2)2H CF3A539 HPh H CF3A540 HPhO H CF3A541 HPhS H CF3A542 HPhSOH CF3A543 HPhSO2H CF3A544 HCH3S H CF3A545 HCH3SO H CF3化合物 R79R80R81R82序号A546 H CF3HCF3A547 H F2CHHCF3A548 H HCC HCF3A549 H CH3CC HCF3A550 H CH2＝CH HCF3A551 H CH2＝CHCH2HCF3A552 H CH3SO2N(CH3) HCF3A553 H (CH3)2N HCF3A554 H (CH3)2NSO2HCF3A555 H CH3SCH2HCF3A556 H CH3SOCH2HCF3A557 H CH3SO2CH2HCF3A558 H CH3HCF3CF2A559 H CH3CH2HCF3CF2A560 H 环丙基 HCF3CF2A561 H (CH3)3C HCF3CF2A562 H (CH3)2CH HCF3CF2A563 H CH3(CH2)2HCF3CF2A564 H CH3OCH2HCF3CF2A565 H CH3O(CH2)2HCF3CF2A566 H Ph HCF3CF2A567 H PhO HCF3CF2A568 H PhS HCF3CF2A569 H PhSO HCF3CF2A570 H PhSO2HCF3CF2A571 H CH3SHCF3CF2A572 H CH3SO HCF3CF2A573 H CF3HCF3CF2A574 H F2CHHCF3CF2A575 H HCC HCF3CF2A576 H CH3CC HCF3CF2A577 H CH2＝CH HCF3CF2化合物 R79R80R81R82序号A578HCH2＝CHCH2HCF3CF2A579HCH3SO2N(CH3) HCF3CF2A580H(CH3)2N HCF3CF2A581H(CH3)2NSO2HCF3CF2A582HCH3SCH2HCF3CF2A583HCH3SOCH2HCF3CF2A584HCH3SO2CH2HCF3CF2A585HCH3HCF3CF2CF2A586HCH3CH2HCF3CF2CF2A587H环丙基 HCF3CF2CF2A588H(CH3)3C HCF3CF2CF2A589H(CH3)2CHHCF3CF2CF2A590HCH3(CH2)2HCF3CF2CF2A591HCH3OCH2HCF3CF2CF2A592HCH3O(CH2)2HCF3CF2CF2A593HPh HCF3CF2CF2A594HPhOHCF3CF2CF2A595HPhSHCF3CF2CF2A596HPhSO HCF3CF2CF2A597HPhSO2HCF3CF2CF2A598HCH3S HCF3CF2CF2A599HCH3SO HCF3CF2CF2A600HCF3HCF3CF2CF2A601HF2CH HCF3CF2CF2A602HHCCHCF3CF2CF2A603HCH3CC HCF3CF2CF2A604HCH2＝CH HCF3CF2CF2A605HCH2＝CHCH2HCF3CF2CF2A606HCH3SO2N(CH3) HCF3CF2CF2A607H(CH3)2N HCF3CF2CF2A608H(CH3)2NSO2HCF3CF2CF2A609HCH3SCH2HCF3CF2CF2化合物 R79R80R81R82序号A610HCH3SOCH2HCF3CF2CF2A611HCH3SO2CH2HCF3CF2CF2A612HCH3HCF2ClA613HCH3CH2HCF2ClA614H环丙基 HCF2ClA615H(CH3)3C HCF2ClA616H(CH3)2CHHCF2ClA617HCH3(CH2)2HCF2ClA618HCH3OCH2HCF2ClA619HCH3O(CH2)2HCF2ClA620HPh HCF2ClA621HPhOHCF2ClA622HPhSHCF2ClA623HPhSO HCF2ClA624HPhSO2HCF2ClA625HCH3S HCF2ClA626HCH3SO HCF2ClA627HCF3HCF2ClA628HF2CH HCF2ClA629HHCCHCF2ClA630HCH3CC HCF2ClA631HCH2＝CH HCF2ClA632HCH2＝CHCH2HCF2ClA633HCH3SO2N(CH3) HCF2ClA634H(CH3)2N HCF2ClA635H(CH3)2NSO2HCF2ClA636HCH3SCH2HCF2ClA637HCH3SOCH2HCF2ClA638HCH3SO2CH2HCF2ClA639HCH3HCHF2A640HCH3CH2HCHF2A641H环丙基 HCHF2化合物 R79R80R81R82序号A642H(CH3)3C HCHF2A643H(CH3)2CH HCHF2A644HCH3(CH2)2HCHF2A645HCH3OCH2HCHF2A646HCH3O(CH2)2HCHF2A647HPh HCHF2A648HPhO HCHF2A649HPhS HCHF2A650HPhSOHCHF2A651HPhSO2HCHF2A652HCH3S HCHF2A653HCH3SO HCHF2A654HCF3HCHF2A655HF2CH HCHF2A656HHCC HCHF2A657HCH3CC HCHF2A658HCH2＝CHHCHF2A659HCH2＝CHCH2HCHF2A660HCH3SO2N(CH3)HCHF2A661H(CH3)2N HCHF2A662H(CH3)2NSO2HCHF2A663HCH3SCH2HCHF2A664HCH3SOCH2HCHF2A665HCH3SO2CH2HCHF2A666HCH3HCCl3A667HCH3CH2HCCl3A668H环丙基 HCCl3A669H(CH3)3C HCCl3A670H(CH3)2CH HCCl3A671HCH3(CH2)2HCCl3A672HCH3OCH2HCCl3A673HCH3O(CH2)2HCCl3化合物 R79R80R81R82序号A674HPh HCCl3A675HPhOHCCl3A676HPhSHCCl3A677HPhSO HCCl3A678HPhSO2HCCl3A679HCH3S HCCl3A680HCH3SO HCCl3A681HCF3HCCl3A682HF2CH HCCl3A683HHCCHCCl3A684HCH3CC HCCl3A685HCH2＝CH HCCl3A686HCH2＝CHCH2HCCl3A687HCH3SO2N(CH3)HCCl3A688H(CH3)2N HCCl3A689H(CH3)2NSO2HCCl3A690HCH3SCH2HCCl3A691HCH3SOCH2HCCl3A692HCH3SO2CH2HCCl3A693HCH3CH3CF3A694HCH3CH2CH3CF3A695H环丙基 CH3CF3A696H(CH3)3C CH3CF3A697H(CH3)2CH CH3CF3A698HCH3(CH2)2CH3CF3A699HCH3OCH2CH3CF3A700HCH3O(CH2)2CH3CF3A701HPh CH3CF3A702HPhOCH3CF3A703HPhSCH3CF3A704HPhSO CH3CF3A705HPhSO2CH3CF3化合物. R79R80R81R82序号A706 H CH3SCH3CF3A707 H CH3SO CH3CF3A708 H CF3CH3CF3A709 H F2CHCH3CF3A710 H HCC CH3CF3A711 H CH3CC CH3CF3A712 H CH2＝CH CH3CF3A713 H CH2＝CHCH2CH3CF3A714 H CH3SO2N(CH3) CH3CF3A715 H (CH3)2NCH3CF3A716 H (CH3)2NSO2CH3CF3A717 H CH3SCH2CH3CF3A718 H CH3SOCH2CH3CF3A719 H CH3SO2CH2CH3CF3A720 H CH3CH3CF3CF2A721 H CH3CH2CH3CF3CF2A722 H 环丙基 CH3CF3CF2A723 H (CH3)3CCH3CF3CF2A724 H (CH3)2CH CH3CF3CF2A725 H CH3(CH2)2CH3CF3CF2A726 H CH3OCH2CH3CF3CF2A727 H CH3O(CH2)2CH3CF3CF2A728 H Ph CH3CF3CF2A729 H PhO CH3CF3CF2A730 H PhS CH3CF3CF2A731 H PhSO CH3CF3CF2A732 H PhSO2CH3CF3CF2A733 H CH3SCH3CF3CF2A734 H CH3SO CH3CF3CF2A735 H CF3CH3CF3CF2A736 H F2CHCH3CF3CF2A737 H HCC CH3CF3CF2化合物R79R80R81R82序号A738 H CH3CC CH3CF3CF2A739 H CH2＝CH CH3CF3CF2A740 H CH2＝CHCH2CH3CF3CF2A741 H CH3SO2N(CH3) CH3CF3CF2A742 H (CH3)2N CH3CF3CF2A743 H (CH3)2NSO2CH3CF3CF2A744 H CH3SCH2CH3CF3CF2A745 H CH3SOCH2CH3CF3CF2A746 H CH3SO2CH2CH3CF3CF2A747 H CH3CH3CF3CF2CF2A748 H CH3CH2CH3CF3CF2CF2A749 H 环丙基 CH3CF3CF2CF2A750 H (CH3)3C CH3CF3CF2CF2A751 H (CH3)2CH CH3CF3CF2CF2A752 H CH3(CH2)2CH3CF3CF2CF2A753 H CH3OCH2CH3CF3CF2CF2A754 H CH3O(CH2)2CH3CF3CF2CF2A755 H Ph CH3CF3CF2CF2A756 H PhO CH3CF3CF2CF2A757 H PhS CH3CF3CF2CF2A758 H PhSO CH3CF3CF2CF2A759 H PhSO2CH3CF3CF2CF2A760 H CH3SCH3CF3CF2CF2A761 H CH3SO CH3CF3CF2CF2A762 H CF3CH3CF3CF2CF2A763 H F2CHCH3CF3CF2CF2A764 H HCC CH3CF3CF2CF2A765 H CH3CC CH3CF3CF2CF2A766 H CH2＝CH CH3CF3CF2CF2A767 H CH2＝CHCH2CH3CF3CF2CF2A768 H CH3SO2N(CH3) CH3CF3CF2CF2A769 H (CH3)2N CH3CF3CF2CF2化合物R79R80R81R82序号A770 H (CH3)2NSO2CH3CF3CF2CF2A771 H CH3SCH2CH3CF3CF2CF2A772 H CH3SOCH2CH3CF3CF2CF2A773 H CH3SO2CH2CH3CF3CF2CF2A774 H CH3CH3CF2ClA775 H CH3CH2CH3CF2ClA776 H 环丙基 CH3CF2ClA777 H (CH3)3C CH3CF2ClA778 H (CH3)2CH CH3CF2ClA779 H CH3(CH2)2CH3CF2ClA780 H CH3OCH2CH3CF2ClA781 H CH3O(CH2)2CH3CF2ClA782 H Ph CH3CF2ClA783 H PhO CH3CF2ClA784 H PhS CH3CF2ClA785 H PhSOCH3CF2ClA786 H PhSO2CH3CF2ClA787 H CH3S CH3CF2ClA788 H CH3SO CH3CF2ClA789 H CF3CH3CF2ClA790 H F2CH CH3CF2ClA791 H HCC CH3CF2ClA792 H CH3CC CH3CF2ClA793 H CH2＝CHCH3CF2ClA794 H CH2＝CHCH2CH3CF2ClA795 H CH3SO2N(CH3)CH3CF2ClA796 H (CH3)2N CH3CF2ClA797 H (CH3)2NSO2CH3CF2ClA798 H CH3SCH2CH3CF2ClA799 H CH3SOCH2CH3CF2ClA800 H CH3SO2CH2CH3CF2ClA801 H CH3CH3CHF2化合物R79R80R81R82序号A802 H CH3CH2CH3CHF2A803 H 环丙基 CH3CHF2A804 H (CH3)3C CH3CHF2A805 H (CH3)2CH CH3CHF2A806 H CH3(CH2)2CH3CHF2A807 H CH3OCH2CH3CHF2A808 H CH3O(CH2)2CH3CHF2A809 H Ph CH3CHF2A810 H PhO CH3CHF2A811 H PhS CH3CHF2A812 H PhSOCH3CHF2A813 H PhSO2CH3CHF2A814 H CH3S CH3CHF2A815 H CH3SO CH3CHF2A816 H CF3CH3CHF2A817 H F2CH CH3CHF2A818 H HCC CH3CHF2A819 H CH3CC CH3CHF2A820 H CH2＝CHCH3CHF2A821 H CH2＝CHCH2CH3CHF2A822 H CH3SO2N(CH3) CH3CHF2A823 H (CH3)2N CH3CHF2A824 H (CH3)2NSO2CH3CHF2A825 H CH3SCH2CH3CHF2A826 H CH3SOCH2CH3CHF2A827 H CH3SO2CH2CH3CHF2A828 H CH3CH3CCl3A829 H CH3CH2CH3CCl3A830 H 环丙基 CH3CCl3A831 H (CH3)3C CH3CCl3A832 H (CH3)2CH CH3CCl3A833 H CH3(CH2)2CH3CCl3化合物R79R80R81R82序号A834 H CH3OCH2CH3CCl3A835 H CH3O(CH2)2CH3CCl3A836 H Ph CH3CCl3A837 H PhO CH3CCl3A838 H PhS CH3CCl3A839 H PhSO CH3CCl3A840 H PhSO2CH3CCl3A841 H CH3SCH3CCl3A842 H CH3SO CH3CCl3A843 H CF3CH3CCl3A844 H F2CHCH3CCl3A845 H HCC CH3CCl3A846 H CH3CC CH3CCl3A847 H CH2＝CH CH3CCl3A848 H CH2＝CHCH2CH3CCl3A849 H CH3SO2N(CH3) CH3CCl3A850 H (CH3)2NCH3CCl3A851 H (CH3)2NSO2CH3CCl3A852 H CH3SCH2CH3CCl3A853 H CH3SOCH2CH3CCl3A854 H CH3SO2CH2CH3CCl3A855 H CH3PhCF3A856 H CH3CH2PhCF3A857 H (CH3)2CH PhCF3A858 H (CH3)2CH PhCF3A859 H 环丙基 PhCF3A860 H CH3(CH2)2PhCF3A861 H CH3OCH2PhCF3A862 H CH3O(CH2)2PhCF3A863 H Ph PhCF3A864 H PhO PhCF3A865 H PhS PhCF3化合物R79R80R81R82序号A866 H PhSOPh CF3A867 H PhSO2Ph CF3A868 H CH3S Ph CF3A869 H CH3SO Ph CF3A870 H CF3Ph CF3A871 H F2CH Ph CF3A872 H HCC Ph CF3A873 H CH3CC Ph CF3A874 H CH2＝CHPh CF3A875 H CH2＝CHCH2Ph CF3A876 H CH3SO2N(CH3)Ph CF3A877 H (CH3)2N Ph CF3A878 H (CH3)2NSO2Ph CF3A879 H CH3SCH2Ph CF3A880 H CH3SOCH2Ph CF3A881 H CH3SO2CH2Ph CF3A882 H CH3Ph CF3CF2A883 H CH3CH2Ph CF3CF2A884 H 环丙基 Ph CF3CF2A885 H (CH3)3C Ph CF3CF2A886 H (CH3)2CH Ph CF3CF2A887 H CH3(CH2)2Ph CF3CF2A888 H CH3OCH2Ph CF3CF2A889 H CH3O(CH2)2Ph CF3CF2A890 H Ph Ph CF3CF2A891 H PhO Ph CF3CF2A892 H PhS Ph CF3CF2A893 H PhSOPh CF3CF2A894 H PhSO2Ph CF3CF2A895 H CH3S Ph CF3CF2A896 H CH3SO Ph CF3CF2A897 H CF3Ph CF3CF2化合物 R79R80R81R82序号A898 H F2CH Ph CF3CF2A899 H HCC Ph CF3CF2A900 H CH3CCPh CF3CF2A901 H CH2＝CH Ph CF3CF2A902 H CH2＝CHCH2Ph CF3CF2A903 H CH3SO2N(CH3) Ph CF3CF2A904 H (CH3)2NPh CF3CF2A905 H (CH3)2NSO2Ph CF3CF2A906 H CH3SCH2Ph CF3CF2A907 H CH3SOCH2Ph CF3CF2A908 H CH3SO2CH2Ph CF3CF2A909 H CH3Ph CF3CF2CF2A910 H CH3CH2Ph CF3CF2CF2A911 H 环丙基Ph CF3CF2CF2A912 H (CH3)3CPh CF3CF2CF2A913 H (CH3)2CPh CF3CF2CF2A914 H CH3(CH2)2Ph CF3CF2CF2A915 H CH3OCH2Ph CF3CF2CF2A916 H CH3O(CH2)2Ph CF3CF2CF2A917 H PhPh CF3CF2CF2A918 H PhO Ph CF3CF2CF2A919 H PhS Ph CF3CF2CF2A920 H PhSO Ph CF3CF2CF2A921 H PhSO2Ph CF3CF2CF2A922 H CH3S Ph CF3CF2CF2A923 H CH3SOPh CF3CF2CF2A924 H CF3Ph CF3CF2CF2A925 H F2CH Ph CF3CF2CF2A926 H HCC Ph CF3CF2CF2A927 H CH3CCPh CF3CF2CF2A928 H CH2＝CH Ph CF3CF2CF2A929 H CH2＝CHCH2Ph CF3CF2CF2化合物R79R80R81R82序号A930 H CH3SO2N(CH3) PhCF3CF2CF2A931 H (CH3)2N PhCF3CF2CF2A932 H (CH3)2NSO2PhCF3CF2CF2A933 H CH3SCH2PhCF3CF2CF2A934 H CH3SOCH2PhCF3CF2CF2A935 H CH3SO2CH2PhCF3CF2CF2A936 H CH3PhCF2ClA937 H CH3CH2PhCF2ClA938 H 环丙基 PhCF2ClA939 H (CH3)3C PhCF2ClA940 H (CH3)2CH PhCF2ClA941 H CH3(CH2)2PhCF2ClA942 H CH3OCH2PhCF2ClA943 H CH3O(CH2)2PhCF2ClA944 H Ph PhCF2ClA945 H PhO PhCF2ClA946 H PhS PhCF2ClA947 H PhSO PhCF2ClA948 H PhSO2PhCF2ClA949 H CH3SPhCF2ClA950 H CH3SO PhCF2ClA951 H CF3PhCF2ClA952 H F2CHPhCF2ClA953 H HCC PhCF2ClA954 H CH3CC PhCF2ClA955 H CH2＝CH PhCF2ClA956 H CH2＝CHCH2PhCF2ClA957 H CH3SO2N(CH3) PhCF2ClA958 H (CH3)2N PhCF2ClA959 H (CH3)2NSO2PhCF2ClA960 H CH3SCH2PhCF2ClA961 H CH3SOCH2PhCF2Cl化合物 R79R80R81R82序号A962H CH3SO2CH2Ph CF2ClA963H CH3Ph CHF2A964H CH3CH2Ph CHF2A965H (CH3)3C Ph CHF2A966H (CH3)2CH Ph CHF2A967H 环丙基 Ph CHF2A968H CH3(CH2)2Ph CHF2A969H CH3OCH2Ph CHF2A970H CH3O(CH2)2Ph CHF2A971H Ph Ph CHF2A972H PhO Ph CHF2A973H PhS Ph CHF2A974H PhSOPh CHF2A975H PhSO2Ph CHF2A976H CH3S Ph CHF2A977H CH3SO Ph CHF2A978H CF3Ph CHF2A979H F2CH Ph CHF2A980H HCC Ph CHF2A981H CH3CC Ph CHF2A982H CH2＝CHPh CHF2A983H CH2＝CHCH2Ph CHF2A984H CH3SO2N(CH3) Ph CHF2A985H (CH3)2N Ph CHF2A986H (CH3)2NSO2Ph CHF2A987H CH3SCH2Ph CHF2A988H CH3SOCH2Ph CHF2A989H CH3SO2CH2Ph CHF2A990H CH3Ph CCl3A991H CH3CH2Ph CCl3A992H (CH3)3C Ph CCl3A993H (CH3)2CH Ph CCl3化合物 R79R80R81R82序号A994 H 环丙基 Ph CCl3A995 H CH3(CH2)2Ph CCl3A996 H CH3OCH2Ph CCl3A997 H CH3O(CH2)2Ph CCl3A998 H Ph Ph CCl3A999 H PhO Ph CCl3A1000H PhS Ph CCl3A1001H PhSO Ph CCl3A1002H PhSO2Ph CCl3A1003H CH3SPh CCl3A1004H CH3SO Ph CCl3A1005H CF3Ph CCl3A1006H F2CHPh CCl3A1007H HCC Ph CCl3A1008H CH3CC Ph CCl3A1009H CH2＝CH Ph CCl3A1010H CH2＝CHCH2Ph CCl3A1011H CH3SO2N(CH3) Ph CCl3A1012H (CH3)2N Ph CCl3A1013H (CH3)2NSO2Ph CCl3A1014H CH3SCH2Ph CCl3A1015H CH3SOCH2Ph CCl3A1016H CH3SO2CH2Ph CCl3A1017F HH CF3A1018Cl HH CF3A1019Br HH CF3A1020CN HH CF3A1021CH3SO2O HH CF3A1022CH3O HH CF3A1023CH2CH3O HH CF3A1024CH2CH＝CH2O HH CF3A1025HCCCH2O HH CF3化合物 R79R80R81R82序号A1026 S-苄基 H H CF3A1027 SO2-苄基H H CF3A1028 ClCH2H H CF3A1029 BrCH2H H CF3A1030 FCH2H H CF3A1031 CHF2CH2H H CF3A1032 CF3CH2H H CF3A1033 三唑基甲基 H H CF3A1034 CHCl2CH2H H CF3A1035 ClCH＝CH H H CF3A1036 Cl2C＝CHH H CF3A1037 CF3CH＝CH H H CF3A1038 ClCC H H CF3A1039 Ph H H CF3A1040 CH3CH3H CF3A1041 CH3OH H CF3A1042 CH3F H CF3A1043 CH3Cl H CF3A1044 FCH3H CF3A1045 Cl CH3H CF3A1046 HF H CF3A1047 HCl H CF3A1048 HBr H CF3A1049 HOH H CF3A1050 HOCH3H CF3A1051 HOCHF2H CF3A1052 HOSO2CH3H CF3A1053 HOSO2CF3H CF3A1054 HClCH2H CF3A1055 HBrCH2H CF3A1056 HFCH2H CF3A1057 HCHF2CH2H CF3化合物 R79R80R81R82序号A1058 H CF3CH2H CF3A1059 H 三唑基甲基 H CF3A1060 H CHCl2CH2H CF3A1061 H ClCH＝CHH CF3A1062 H Cl2C＝CH H CF3A1063 H CF3CH＝CH H CF3A1064 H ClCCH CF3A1065 H CH3C(O)H CF3A1066 H 苯基H CF3A1067 H SO2CH3H CF3A1068 H SO2CF3H CF3A1069 H CN H CF3A1070 H NO2H CF3A1071 CH3H F CF3A1072 CH3H Cl CF3A1073 CH3H Br CF3A1074 CH3H CN CF3A1075 CH3H CH3O CF3A1076 CH3H CH3S CF3A1077 CH3H CH3SO CF3A1078 CH3H CH3SO2CF3在下表6中，Q是Q3 且Q3代表下列基团B表6基团B基团 R44R37R38R39R40WB1H HHHOHCH2B2CH3HHHOHCH2B3CH3CH2HHHOHCH2B4CH3CH2CH2HHHOHCH2B5(CH3)2CHHHHOHCH2B6(CH3)3C HHHOHCH2B7CH3S HHHOHCH2B8CH3SOHHHOHCH2B9CH3SO2HHHOHCH2B10 PhHHHOHCH2B11 CH3O HHHOHCH2B12 CH3CO2HHHOHCH2B13 CH3CH2CO2HHHOHCH2B14 CH2＝CHCH2HHHOHCH2B15 HCCCH2HHHOHCH2B16 CF3HHHOHCH2B17 (CH3)2NSO2HHHOHCH2B18 (CH3)2N HHHOHCH2B19 PhO HHHOHCH2B20 PhS HHHOHCH2B21 PhSO HHHOHCH2B22 PhSO2HHHOHCH2B23 CNHHHOHCH2B24 CH3CH3HHOHCH2B25 CH3CH2CH3HHOHCH2B26 CH3CH2CH2CH3HHOHCH2B27 (CH3)2CHCH3HHOHCH2B28 (CH3)3C CH3HHOHCH2B29 CH3S CH3HHOHCH2B30 CH3SOCH3HHOHCH2B31 CH3SO2CH3HHOHCH2B32 PhCH3HHOHCH2基团R44R37R38R39R40WB33 CH3O CH3H H OH CH2B34 CH3CO2CH3H H OH CH2B35 CH3CH2CO2CH3H H OH CH2B36 CH2＝CHCH2CH3H H OH CH2B37 HCCCH2CH3H H OH CH2B38 CF3CH3H H OH CH2B39 (CH3)2NSO2CH3H H OH CH2B40 (CH3)2N CH3H H OH CH2B41 PhOCH3H H OH CH2B42 PhSCH3H H OH CH2B43 PhSO CH3H H OH CH2B44 PhSO2CH3H H OH CH2B45 CN CH3H H OH CH2B46 CH3H CH3H OH CH2B47 CH3CH2H CH3H OH CH2B48 CH3CH2CH2H CH3H OH CH2B49 (CH3)2CH H CH3H OH CH2B50 (CH3)3C H CH3H OH CH2B51 CH3S H CH3H OH CH2B52 CH3SO H CH3H OH CH2B53 CH3SO2H CH3H OH CH2B54 Ph H CH3H OH CH2B55 CH3O H CH3H OH CH2B56 CH3CO2H CH3H OH CH2B57 CH3CH2CO2H CH3H OH CH2B58 CH2＝CHCH2H CH3H OH CH2B59 HCCCH2H CH3H OH CH2B60 CF3H CH3H OH CH2B61 (CH3)2NSO2H CH3H OH CH2B62 (CH3)2N H CH3H OH CH2B63 PhOH CH3H OH CH2B64 PhSH CH3H OH CH2B65 PhSO H CH3H OH CH2基团R44R37R38R39R40WB66 PhSO2HCH3H OH CH2B67 CN HCH3H OH CH2B68 CH3CH3CH3H OH CH2B69 CH3CH2CH3CH3H OH CH2B70 CH3CH2CH2CH3CH3H OH CH2B71 (CH3)2CH CH3CH3H OH CH2B72 (CH3)3C CH3CH3H OH CH2B73 CH3S CH3CH3H OH CH2B74 CH3SO CH3CH3H OH CH2B75 CH3SO2CH3CH3H OH CH2B76 Ph CH3CH3H OH CH2B77 CH3O CH3CH3H OH CH2B78 CH3CO2CH3CH3H OH CH2B79 CH3CH2CO2CH3CH3H OH CH2B80 CH2＝CHCH2CH3CH3H OH CH2B81 HCCCH2CH3CH3H OH CH2B82 CF3CH3CH3H OH CH2B83 (CH3)2NSO2CH3CH3H OH CH2B84 (CH3)2N CH3CH3H OH CH2B85 PhOCH3CH3H OH CH2B86 PhSCH3CH3H OH CH2B87 PhSO CH3CH3H OH CH2B88 PhSO2CH3CH3H OH CH2B89 CN CH3CH3H OH CH2B90 CH3CH3CH3CH3OH CH2B91 CH3CH2CH3CH3CH3OH CH2B92 CH3CH2CH2CH3CH3CH3OH CH2B93 (CH3)2CH CH3CH3CH3OH CH2B94 (CH3)3C CH3CH3CH3OH CH2B95 CH3S CH3CH3CH3OH CH2B96 CH3SO CH3CH3CH3OH CH2B97 CH3SO2CH3CH3CH3OH CH2B98 Ph CH3CH3CH3OH CH2基团 R44R37R38R39R40WB99 CH3OCH3CH3CH3OH CH2B100 CH3CO2CH3CH3CH3OH CH2B101 CH3CH2CO2CH3CH3CH3OH CH2B102 CH2＝CHCH2CH3CH3CH3OH CH2B103 HCCCH2CH3CH3CH3OH CH2B104 CF3CH3CH3CH3OH CH2B105 (CH3)2NSO2CH3CH3CH3OH CH2B106 (CH3)2NCH3CH3CH3OH CH2B107 PhO CH3CH3CH3OH CH2B108 PhS CH3CH3CH3OH CH2B109 PhSO CH3CH3CH3OH CH2B110 PhSO2CH3CH3CH3OH CH2B111 CNCH3CH3CH3OH CH2B112 CH3CH2CH3CH2H H OH CH2B113 CH3CH2CH2CH3CH2H H OH CH2B114 (CH3)2CH CH3CH2H H OH CH2B115 (CH3)3CCH3CH2H H OH CH2B116 CH3SCH3CH2H H OH CH2B117 CH3SO CH3CH2H H OH CH2B118 CH3SO2CH3CH2H H OH CH2B119 Ph CH3CH2H H OH CH2B120 CH3OCH3CH2H H OH CH2B121 CH3CO2CH3CH2H H OH CH2B122 CH3CH2CO2CH3CH2H H OH CH2B123 CH2＝CHCH2CH3CH2H H OH CH2B124 HCCCH2CH3CH2H H OH CH2B125 CF3CH3CH2H H OH CH2B126 (CH3)2NSO2CH3CH2H H OH CH2B127 (CH3)2N CH3CH2H H OH CH2B128 PhO CH3CH2H H OH CH2B129 PhS CH3CH2H H OH CH2B130 PhSO CH3CH2H H OH CH2B131 PhSO2CH3CH2H H OH CH2基团 R44R37R38R39R40WB132 CNCH3CH2H H OHCH2B133 H H H H OHCHCH3B134 CH3H H H OHCHCH3B135 CH3CH2H H H OHCHCH3B136 CH3CH2CH2H H H OHCHCH3B137 (CH3)2CHH H H OHCHCH3B138 (CH3)3C H H H OHCHCH3B139 CH3S H H H OHCHCH3B140 CH3SOH H H OHCHCH3B141 CH3SO2H H H OHCHCH3B142 PhH H H OHCHCH3B143 CH3O H H H OHCHCH3B144 CH3CO2H H H OHCHCH3B145 CH3CH2CO2H H H OHCHCH3B146 CH2＝CHCH2H H H OHCHCH3B147 HCCCH2H H H OHCHCH3B148 CF3H H H OHCHCH3B149 (CH3)2NSO2H H H OHCHCH3B150 (CH3)2N H H H OHCHCH3B151 PhO H H H OHCHCH3B152 PhS H H H OHCHCH3B153 PhSO H H H OHCHCH3B154 PhSO2H H H OHCHCH3B155 CNH H H OHCHCH3B156 CH3CH3H H OHCHCH3B157 CH3CH2CH3H H OHCHCH3B158 CH3CH2CH2CH3H H OHCHCH3B159 (CH3)2CHCH3H H OHCHCH3B160 (CH3)3C CH3H H OHCHCH3B161 CH3S CH3H H OHCHCH3B162 CH3SOCH3H H OHCHCH3B163 CH3SO2CH3H H OHCHCH3B164 PhCH3HH OHCHCH3基团R44R37R38R39R40WB165CH3O CH3H HOHCHCH3B166CH3CO2CH3H HOHCHCH3B167CH3CH2CO2CH3H HOHCHCH3B168CH2＝CHCH2CH3H HOHCHCH3B169HCCCH2CH3H HOHCHCH3B170CF3CH3H HOHCHCH3B171(CH3)2NSO2CH3H HOHCHCH3B172(CH3)2NCH3H HOHCHCH3B173PhO CH3H HOHCHCH3B174PhS CH3H HOHCHCH3B175PhSO CH3H HOHCHCH3B176PhSO2CH3H HOHCHCH3B177CNCH3H HOHCHCH3B178CH3HCH3HOHCHCH3B179CH3CH2HCH3HOHCHCH3B180CH3CH2CH2HCH3HOHCHCH3B181(CH3)2CHHCH3HOHCHCH3B182(CH3)3C HCH3HOHCHCH3B183CH3S HCH3HOHCHCH3B184CH3SOHCH3HOHCHCH3B185CH3SO2HCH3HOHCHCH3B186PhHCH3HOHCHCH3B187CH3O HCH3HOHCHCH3B188CH3CO2HCH3HOHCHCH3B189CH3CH2CO2HCH3HOHCHCH3B190CH2＝CHCH2HCH3HOHCHCH3B191HCCCH2HCH3HOHCHCH3B192CF3HCH3HOHCHCH3B193(CH3)2NSO2HCH3HOHCHCH3B194(CH3)2NHCH3HOHCHCH3B195PhO HCH3HOHCHCH3B196PhS HCH3HOHCHCH3B197PhSO HCH3HOHCHCH3基团R44R37R38R39R40WB198PhSO2H CH3HOHCHCH3B199CN H CH3HOHCHCH3B200CH3CH3CH3HOHCHCH3B201CH3CH2CH3CH3HOHCHCH3B202CH3CH2CH2CH3CH3HOHCHCH3B203(CH3)2CH CH3CH3HOHCHCH3B204(CH3)3C CH3CH3HOHCHCH3B205CH3S CH3CH3HOHCHCH3B206CH3SO CH3CH3HOHCHCH3B207CH3SO2CH3CH3HOHCHCH3B208Ph CH3CH3HOHCHCH3B209CH3O CH3CH3HOHCHCH3B210CH3CO2CH3CH3HOHCHCH3B211CH3CH2CO2CH3CH3HOHCHCH3B212CH2＝CHCH2CH3CH3HOHCHCH3B213HCCCH2CH3CH3HOHCHCH3B214CF3CH3CH3HOHCHCH3B215(CH3)2NSO2CH3CH3HOHCHCH3B216(CH3)2N CH3CH3HOHCHCH3B217PhO CH3CH3HOHCHCH3B218PhS CH3CH3HOHCHCH3B219PhSOCH3CH3HOHCHCH3B220PhSO2CH3CH3HOHCHCH3B221CN CH3CH3HOHCHCH3B222CH3CH3CH3CH3OHCHCH3B223CH3CH2CH3CH3CH3OHCHCH3B224CH3CH2CH2CH3CH3CH3OHCHCH3B225(CH3)2CH CH3CH3CH3OHCHCH3B226(CH3)3C CH3CH3CH3OHCHCH3B227CH3S CH3CH3CH3OHCHCH3B228CH3SO CH3CH3CH3OHCHCH3B229CH3SO2CH3CH3CH3OHCHCH3B230Ph CH3CH3CH3OHCHCH3基团R44R37R38R39R40WB231CH3O CH3CH3CH3OHCHCH3B232CH3CO2CH3CH3CH3OHCHCH3B233CH3CH2CO2CH3CH3CH3OHCHCH3B234CH2＝CHCH2CH3CH3CH3OHCHCH3B235HCCCH2CH3CH3CH3OHCHCH3B236CF3CH3CH3CH3OHCHCH3B237(CH3)2NSO2CH3CH3CH3OHCHCH3B238(CH3)2N CH3CH3CH3OHCHCH3B239PhO CH3CH3CH3OHCHCH3B240PhS CH3CH3CH3OHCHCH3B241PhSOCH3CH3CH3OHCHCH3B242PhSO2CH3CH3CH3OHCHCH3B243CN CH3CH3CH3OHCHCH3B244CH3CH2CH3CH2HHOHCHCH3B245CH3CH2CH2CH3CH2HHOHCHCH3B246(CH3)2CH CH3CH2HHOHCHCH3B247(CH3)3C CH3CH2HHOHCHCH3B248CH3S CH3CH2HHOHCHCH3B249CH3SO CH3CH2HHOHCHCH3B250CH3SO2CH3CH2HHOHCHCH3B251Ph CH3CH2HHOHCHCH3B252CH3O CH3CH2HHOHCHCH3B253CH3CO2CH3CH2HHOHCHCH3B254CH3CH2CO2CH3CH2HHOHCHCH3B255CH2＝CHCH2CH3CH2HHOHCHCH3B256HCCCH2CH3CH2HHOHCHCH3B257CF3CH3CH2HHOHCHCH3B258(CH3)2NSO2CH3CH2HHOHCHCH3B259(CH3)2N CH3CH2HHOHCHCH3B260PhOCH3CH2HHOHCHCH3B261PhSCH3CH2HHOHCHCH3B262PhSO CH3CH2HHOHCHCH3B263PhSO2CH3CH2HHOHCHCH3基团R44R37R38R39R40WB264CN CH3CH2H HOH CHCH3B265H H H HOH C＝OB266CH3H H HOH C＝OB267CH3CH2H H HOH C＝OB268CH3CH2CH2H H HOH C＝OB269(CH3)2CH H H HOH C＝OB270(CH3)3C H H HOH C＝OB271CH3S H H HOH C＝OB272CH3SO H H HOH C＝OB273CH3SO2H H HOH C＝OB274Ph H H HOH C＝OB275CH3O H H HOH C＝OB276CH3CO2H H HOH C＝OB277CH3CH2CO2H H HOH C＝OB278CH2＝CHCH2H H HOH C＝OB279HCCCH2H H HOH C＝OB280CF3H H HOH C＝OB281(CH3)2NSO2H H HOH C＝OB282(CH3)2N H H HOH C＝OB283PhOH H HOH C＝OB284PhSH H HOH C＝OB285PhSO H H HOH C＝OB286PhSO2H H HOH C＝OB287CN H H HOH C＝OB288CH3CH3H HOH C＝OB289CH3CH2CH3H HOH C＝OB290CH3CH2CH2CH3H HOH C＝OB291(CH3)2CH CH3H HOH C＝OB292(CH3)3C CH3H HOH C＝OB293CH3S CH3H HOH C＝OB294CH3SO CH3H HOH C＝OB295CH3SO2CH3H HOH C＝OB296Ph CH3H HOH C＝O基团 R44R37R38R39R40WB297 CH3OCH3H HOH C＝OB298 CH3CO2CH3H HOH C＝OB299 CH3CH2CO2CH3H HOH C＝OB300 CH2＝CHCH2CH3H HOH C＝OB301 HCCCH2CH3H HOH C＝OB302 CF3CH3H HOH C＝OB303 (CH3)2NSO2CH3H HOH C＝OB304 (CH3)2NCH3H HOH C＝OB305 PhO CH3H HOH C＝OB306 PhS CH3H HOH C＝OB307 PhSO CH3H HOH C＝OB308 PhSO2CH3H HOH C＝OB309 CN CH3H HOH C＝OB310 CH3HCH3HOH C＝OB311 CH3CH2HCH3HOH C＝OB312 CH3CH2CH2HCH3HOH C＝OB313 (CH3)2CH HCH3HOH C＝OB314 (CH3)3CHCH3HOH C＝OB315 CH3SHCH3HOH C＝OB316 CH3SO HCH3HOH C＝OB317 CH3SO2HCH3HOH C＝OB318 Ph HCH3HOH C＝OB319 CH3OHCH3HOH C＝OB320 CH3CO2HCH3HOH C＝OB321 CH3CH2CO2HCH3HOH C＝OB322 CH2＝CHCH2HCH3HOH C＝OB323 HCCCH2HCH3HOH C＝OB324 CF3HCH3HOH C＝OB325 (CH3)2NSO2HCH3HOH C＝OB326 (CH3)2N HCH3HOH C＝OB327 PhO HCH3HOH C＝OB328 PhS HCH3HOH C＝OB329 PhSO HCH3HOH C＝O基团 R44R37R38R39R40WB330 PhSO2H CH3H OH C＝OB331 CNH CH3H OH C＝OB332 CH3CH3CH3H OH C＝OB333 CH3CH2CH3CH3H OH C＝OB334 CH3CH2CH2CH3CH3H OH C＝OB335 (CH3)2CHCH3CH3H OH C＝OB336 (CH3)3C CH3CH3H OH C＝OB337 CH3S CH3CH3H OH C＝OB338 CH3SOCH3CH3H OH C＝OB339 CH3SO2CH3CH3H OH C＝OB340 PhCH3CH3H OH C＝OB341 CH3O CH3CH3H OH C＝OB342 CH3CO2CH3CH3H OH C＝OB343 CH3CH2CO2CH3CH3H OH C＝OB344 CH2＝CHCH2CH3CH3H OH C＝OB345 HCCCH2CH3CH3H OH C＝OB346 CF3CH3CH3H OH C＝OB347 (CH3)2NSO2CH3CH3H OH C＝OB348 (CH3)2N CH3CH3H OH C＝OB349 PhO CH3CH3H OH C＝OB350 PhS CH3CH3H OH C＝OB351 PhSO CH3CH3H OH C＝OB352 PhSO2CH3CH3H OH C＝OB353 CNCH3CH3H OH C＝OB354 CH3CH3CH3CH3OH C＝OB355 CH3CH2CH3CH3CH3OH C＝OB356 CH3CH2CH2CH3CH3CH3OH C＝OB357 (CH3)2CHCH3CH3CH3OH C＝OB358 (CH3)3C CH3CH3CH3OH C＝OB359 CH3S CH3CH3CH3OH C＝OB360 CH3SOCH3CH3CH3OH C＝OB361 CH3SO2CH3CH3CH3OH C＝OB362 PhCH3CH3CH3OH C＝O基团 R44R37R38R39R40WB363 CH3O CH3CH3CH3OH C＝OB364 CH3CO2CH3CH3CH3OH C＝OB365 CH3CH2CO2CH3CH3CH3OH C＝OB366 CH2＝CHCH2CH3CH3CH3OH C＝OB367 HCCCH2CH3CH3CH3OH C＝OB368 CF3CH3CH3CH3OH C＝OB369 (CH3)2NSO2CH3CH3CH3OH C＝OB370 (CH3)2N CH3CH3CH3OH C＝OB371 PhO CH3CH3CH3OH C＝OB372 PhS CH3CH3CH3OH C＝OB373 PhSO CH3CH3CH3OH C＝OB374 PhSO2CH3CH3CH3OH C＝OB375 CNCH3CH3CH3OH C＝OB376 CH3CH2CH3CH2H H OH C＝OB377 CH3CH2CH2CH3CH2H H OH C＝OB378 (CH3)2CHCH3CH2H H OH C＝OB379 (CH3)3C CH3CH2H H OH C＝OB380 CH3S CH3CH2H H OH C＝OB381 CH3SO CH3CH2H H OH C＝OB382 CH3SO2CH3CH2H H OH C＝OB383 Ph CH3CH2H H OH C＝OB384 CH3O CH3CH2H H OH C＝OB385 CH3CO2CH3CH2H H OH C＝OB386 CH3CH2CO2CH3CH2H H OH C＝OB387 CH2＝CHCH2CH3CH2H H OH C＝OB388 HCCCH2CH3CH2H H OH C＝OB389 CF3CH3CH2H H OH C＝OB390 (CH3)2NSO2CH3CH2H H OH C＝OB391 (CH3)2NCH3CH2H H OH C＝OB392 PhO CH3CH2H H OH C＝OB393 PhS CH3CH2H H OH C＝OB394 PhSO CH3CH2H H OH C＝OB395 PhSO2CH3CH2H H OH C＝O基团 R44R37R38R39R40WB396 CN CH3CH2H H OH C＝OB397 H H H H OH N-CH3B398 CH3H H H OH N-CH3B399 CH3CH2H H H OH N-CH3B400 CH3CH2CH2H H H OH N-CH3B401 (CH3)2CH H H H OH N-CH3B402 (CH3)3C H H H OH N-CH3B403 CH3S H H H OH N-CH3B404 CH3SO H H H OH N-CH3B405 CH3SO2H H H OH N-CH3B406 Ph H H H OH N-CH3B407 CH3O H H H OH N-CH3B408 CH3CO2H H H OH N-CH3B409 CH3CH2CO2H H H OH N-CH3B410 CH2＝CHCH2H H H OH N-CH3B411 HCCCH2H H H OH N-CH3B412 CF3H H H OH N-CH3B413 (CH3)2NSO2H H H OH N-CH3B414 (CH3)2N H H H OH N-CH3B415 PhO H H H OH N-CH3B416 PhS H H H OH N-CH3B417 PhSOH H H OH N-CH3B418 PhSO2H H H OH N-CH3B419 CN H H H OH N-CH3B420 CH3CH3H H OH N-CH3B421 CH3CH2CH3H H OH N-CH3B422 CH3CH2CH2CH3H H OH N-CH3B423 (CH3)2CH CH3H H OH N-CH3B424 (CH3)3C CH3H H OH N-CH3B425 CH3S CH3H H OH N-CH3B426 CH3SO CH3H H OH N-CH3B427 CH3SO2CH3H H OH N-CH3B428 Ph CH3H H OH N-CH3基团 R44R37R38R39R40WB429 CH3OCH3H H OH N-CH3B430 CH3CO2CH3H H OH N-CH3B431 CH3CH2CO2CH3H H OH N-CH3B432 CH2＝CHCH2CH3H H OH N-CH3B433 HCCCH2CH3H H OH N-CH3B434 CF3CH3H H OH N-CH3B435 (CH3)2NSO2CH3H H OH N-CH3B436 (CH3)2NCH3H H OH N-CH3B437 PhO CH3H H OH N-CH3B438 PhS CH3H H OH N-CH3B439 PhSO CH3H H OH N-CH3B440 PhSO2CH3H H OH N-CH3B441 CN CH3H H OH N-CH3B442 CH3H CH3H OH N-CH3B443 CH3CH2H CH3H OH N-CH3B444 CH3CH2CH2H CH3H OH N-CH3B445 (CH3)2CH H CH3H OH N-CH3B446 (CH3)3CH CH3H OH N-CH3B447 CH3SH CH3H OH N-CH3B448 CH3SO H CH3H OH N-CH3B449 CH3SO2H CH3H OH N-CH3B450 Ph H CH3H OH N-CH3B451 CH3OH CH3H OH N-CH3B452 CH3CO2H CH3H OH N-CH3B453 CH3CH2CO2H CH3H OH N-CH3B454 CH2＝CHCH2H CH3H OH N-CH3B455 HCCCH2H CH3H OH N-CH3B456 CF3H CH3H OH N-CH3B457 (CH3)2NSO2H CH3H OH N-CH3B458 (CH3)2N H CH3H OH N-CH3B459 PhO H CH3H OH N-CH3B460 PhS H CH3H OH N-CH3B461 PhSO H CH3H OH N-CH3基团 R44R37R38R39R40WB462 PhSO2HCH3H OH N-CH3B463 CNHCH3H OH N-CH3B464 CH3CH3CH3H OH N-CH3B465 CH3CH2CH3CH3H OH N-CH3B466 CH3CH2CH2CH3CH3H OH N-CH3B467 (CH3)2CHCH3CH3H OH N-CH3B468 (CH3)3C CH3CH3H OH N-CH3B469 CH3S CH3CH3H OH N-CH3B470 CH3SOCH3CH3H OH N-CH3B471 CH3SO2CH3CH3H OH N-CH3B472 PhCH3CH3H OH N-CH3B473 CH3O CH3CH3H OH N-CH3B474 CH3CO2CH3CH3H OH N-CH3B475 CH3CH2CO2CH3CH3H OH N-CH3B476 CH2＝CHCH2CH3CH3H OH N-CH3B477 HCCCH2CH3CH3H OH N-CH3B478 CF3CH3CH3H OH N-CH3B479 (CH3)2NSO2CH3CH3H OH N-CH3B480 (CH3)2NCH3CH3H OH N-CH3B481 PhO CH3CH3H OH N-CH3B482 PhS CH3CH3H OH N-CH3B483 PhSO CH3CH3H OH N-CH3B484 PhSO2CH3CH3H OH N-CH3B485 CNCH3CH3H OH N-CH3B486 CH3CH3CH3CH3OH N-CH3B487 CH3CH2CH3CH3CH3OH N-CH3B488 CH3CH2CH2CH3CH3CH3OH N-CH3B489 (CH3)2CHCH3CH3CH3OH N-CH3B490 (CH3)3C CH3CH3CH3OH N-CH3B491 CH3S CH3CH3CH3OH N-CH3B492 CH3SOCH3CH3CH3OH N-CH3B493 CH3SO2CH3CH3CH3OH N-CH3B494 PhCH3CH3CH3OH N-CH3基团 R44R37R38R39R40WB495 CH3O CH3CH3CH3OH N-CH3B496 CH3CO2CH3CH3CH3OH N-CH3B497 CH3CH2CO2CH3CH3CH3OH N-CH3B498 CH2＝CHCH2CH3CH3CH3OH N-CH3B499 HCCCH2CH3CH3CH3OH N-CH3B500 CF3CH3CH3CH3OH N-CH3B501 (CH3)2NSO2CH3CH3CH3OH N-CH3B502 (CH3)2N CH3CH3CH3OH N-CH3B503 PhOCH3CH3CH3OH N-CH3B504 PhSCH3CH3CH3OH N-CH3B505 PhSO CH3CH3CH3OH N-CH3B506 PhSO2CH3CH3CH3OH N-CH3B507 CN CH3CH3CH3OH N-CH3B508 CH3CH2CH3CH2H H OH N-CH3B509 CH3CH2CH2CH3CH2H H OH N-CH3B510 (CH3)2CHCH3CH2H H OH N-CH3B511 (CH3)3C CH3CH2H H OH N-CH3B512 CH3S CH3CH2H H OH N-CH3B513 CH3SOCH3CH2H H OH N-CH3B514 CH3SO2CH3CH2H H OH N-CH3B515 PhCH3CH2H H OH N-CH3B516 CH3O CH3CH2H H OH N-CH3B517 CH3CO2CH3CH2H H OH N-CH3B518 CH3CH2CO2CH3CH2H H OH N-CH3B519 CH2＝CHCH2CH3CH2H H OH N-CH3B520 HCCCH2CH3CH2H H OH N-CH3B521 CF3CH3CH2H H OH N-CH3B522 (CH3)2NSO2CH3CH2H H OH N-CH3B523 (CH3)2NCH3CH2H H OH N-CH3B524 PhO CH3CH2H H OH N-CH3B525 PhS CH3CH2H H OH N-CH3B526 PhSO CH3CH2H H OH N-CH3B527 PhSO2CH3CH2H H OH N-CH3基团R44R37R38R39R40WB528CN CH3CH2H H OHN-CH3B529H H H H OH OB530CH3H H H OH OB531CH3CH2H H H OH OB532CH3CH2CH2H H H OH OB533(CH3)2CH H H H OH OB534(CH3)3C H H H OH OB535CH3S H H H OH OB536CH3SO H H H OH OB537CH3SO2H H H OH OB538Ph H H H OH OB539CH3O H H H OH OB540CH3CO2H H H OH OB541CH3CH2CO2H H H OH OB542CH2＝CHCH2H H H OH OB543HCCCH2H H H OH OB544CF3H H H OH OB545(CH3)2NSO2H H H OH OB546(CH3)2N H H H OH OB547PhO H H H OH OB548PhS H H H OH OB549PhSOH H H OH OB550PhSO2H H H OH OB551CN H H H OH OB552CH3CH3H H OH OB553CH3CH2CH3H H OH OB554CH3CH2CH2CH3H H OH OB555(CH3)2CH CH3H H OH OB556(CH3)3C CH3H H OH OB557CH3S CH3H H OH OB558CH3SO CH3H H OH OB559CH3SO2CH3H H OH OB560Ph CH3H H OH O基团 R44R37R38R39R40WB561 CH3O CH3H H OH OB562 CH3CO2CH3H H OH OB563 CH3CH2CO2CH3H H OH OB564 CH2＝CHCH2CH3H H OH OB565 HCCCH2CH3H H OH OB566 CF3CH3H H OH OB567 (CH3)2NSO2CH3H H OH OB568 (CH3)2N CH3H H OH OB569 PhOCH3H H OH OB570 PhSCH3H H OH OB571 PhSO CH3H H OH OB572 PhSO2CH3H H OH OB573 CN CH3H H OH OB574 CH3H CH3H OH OB575 CH3CH2H CH3H OH OB576 CH3CH2CH2H CH3H OH OB577 (CH3)2CH H CH3H OH OB578 (CH3)3C H CH3H OH OB579 CH3S H CH3H OH OB580 CH3SO H CH3H OH OB581 CH3SO2H CH3H OH OB582 Ph H CH3H OH OB583 CH3O H CH3H OH OB584 CH3CO2H CH3H OH OB585 CH3CH2CO2H CH3H OH OB586 CH2＝CHCH2H CH3H OH OB587 HCCCH2H CH3H OH OB588 CF3H CH3H OH OB589 (CH3)2NSO2H CH3H OH OB590 (CH3)2N H CH3H OH OB591 PhOH CH3H OH OB592 PhSH CH3H OH OB593 PhSO H CH3H OH O基团R44R37R38R39R40WB594PhSO2H CH3HOHOB595CN H CH3HOHOB596CH3CH3CH3HOHOB597CH3CH2CH3CH3HOHOB598CH3CH2CH2CH3CH3HOHOB599(CH3)2CH CH3CH3HOHOB600(CH3)3C CH3CH3HOHOB601CH3S CH3CH3HOHOB602CH3SO CH3CH3HOHOB603CH3SO2CH3CH3HOHOB604Ph CH3CH3HOHOB605CH3O CH3CH3HOHOB606CH3CO2CH3CH3HOHOB607CH3CH2CO2CH3CH3HOHOB608CH2＝CHCH2CH3CH3HOHOB609HCCCH2CH3CH3HOHOB610CF3CH3CH3HOHOB611(CH3)2NSO2CH3CH3HOHOB612(CH3)2N CH3CH3HOHOB613PhO CH3CH3HOHOB614PhS CH3CH3HOHOB615PhSOCH3CH3HOHOB616PhSO2CH3CH3HOHOB617CN CH3CH3HOHOB618CH3CH3CH3CH3OHOB619CH3CH2CH3CH3CH3OHOB620CH3CH2CH2CH3CH3CH3OHOB621(CH3)2CH CH3CH3CH3OHOB622(CH3)3C CH3CH3CH3OHOB623CH3S CH3CH3CH3OHOB624CH3SO CH3CH3CH3OHOB625CH3SO2CH3CH3CH3OHOB626Ph CH3CH3CH3OHO基团R44R37R38R39R40WB627CH3O CH3CH3CH3OHOB628CH3CO2CH3CH3CH3OHOB629CH3CH2CO2CH3CH3CH3OHOB630CH2＝CHCH2CH3CH3CH3OHOB631HCCCH2CH3CH3CH3OHOB632CF3CH3CH3CH3OHOB633(CH3)2NSO2CH3CH3CH3OHOB634(CH3)2N CH3CH3CH3OHOB635PhO CH3CH3CH3OHOB636PhS CH3CH3CH3OHOB637PhSO CH3CH3CH3OHOB638PhSO2CH3CH3CH3OHOB639CN CH3CH3CH3OHOB640CH3CH2CH3CH2HHOHOB641CH3CH2CH2CH3CH2HHOHOB642(CH3)2CH CH3CH2HHOHOB643(CH3)3C CH3CH2HHOHOB644CH3S CH3CH2HHOHOB645CH3SO CH3CH2HHOHOB646CH3SO2CH3CH2HHOHOB647Ph CH3CH2HHOHOB648CH3O CH3CH2HHOHOB649CH3CO2CH3CH2HHOHOB650CH3CH2CO2CH3CH2HHOHOB651CH2＝CHCH2CH3CH2HHOHOB652HCCCH2CH3CH2HHOHOB653CF3CH3CH2HHOHOB654(CH3)2NSO2CH3CH2HHOHOB655(CH3)2N CH3CH2HHOHOB656PhO CH3CH2HHOHOB657PhS CH3CH2HHOHOB658PhSOCH3CH2HHOHOB659PhSO2CH3CH2HHOHO基团R44R37R38R39R40WB660CN CH3CH2H H OH OB661H H H H OH SB662CH3H H H OH SB663CH3CH2H H H OH SB664CH3CH2CH2H H H OH SB665(CH3)2CH H H H OH SB666(CH3)3C H H H OH SB667CH3S H H H OH SB668CH3SO H H H OH SB669CH3SO2H H H OH SB670Ph H H H OH SB671CH3O H H H OH SB672CH3CO2H H H OH SB673CH3CH2CO2H H H OH SB674CH2＝CHCH2H H H OH SB675HCCCH2H H H OH SB676CF3H H H OH SB677(CH3)2NSO2H H H OH SB678(CH3)2N H H H OH SB679PhO H H H OH SB680PhS H H H OH SB681PhSOH H H OH SB682PhSO2H H H OH SB683CN H H H OH SB684CH3CH3H H OH SB685CH3CH2CH3H H OH SB686CH3CH2CH2CH3H H OH SB687(CH3)2CH CH3H H OH SB688(CH3)3C CH3H H OH SB689CH3S CH3H H OH SB690CH3SO CH3H H OH SB691CH3SO2CH3H H OH SB692Ph CH3H H OH S基团 R44R37R38R39R40WB693 CH3O CH3HH OH SB694 CH3CO2CH3HH OH SB695 CH3CH2CO2CH3HH OH SB696 CH2＝CHCH2CH3HH OH SB697 HCCCH2CH3HH OH SB698 CF3CH3HH OH SB699 (CH3)2NSO2CH3HH OH SB700 (CH3)2N CH3HH OH SB701 PhO CH3HH OH SB702 PhS CH3HH OH SB703 PhSO CH3HH OH SB704 PhSO2CH3HH OH SB705 CN CH3HH OH SB706 CH3H CH3H OH SB707 CH3CH2H CH3H OH SB708 CH3CH2CH2H CH3H OH SB709 (CH3)2CH H CH3H OH SB710 (CH3)3C H CH3H OH SB711 CH3S H CH3H OH SB712 CH3SO H CH3H OH SB713 CH3SO2H CH3H OH SB714 Ph H CH3H OH SB715 CH3O H CH3H OH SB716 CH3CO2H CH3H OH SB717 CH3CH2CO2H CH3H OH SB718 CH2＝CHCH2H CH3H OH SB719 HCCCH2H CH3H OH SB720 CF3H CH3H OH SB721 (CH3)2NSO2H CH3H OH SB722 (CH3)2N H CH3H OH SB723 PhO H CH3H OH SB724 PhS H CH3H OH SB725 PhSO H CH3H OH S基团 R44R37R38R39R40WB726 PhSO2H CH3H OH SB727 CN H CH3H OH SB728 CH3CH3CH3H OH SB729 CH3CH2CH3CH3H OH SB730 CH3CH2CH2CH3CH3H OH SB731 (CH3)2CH CH3CH3H OH SB732 (CH3)3C CH3CH3H OH SB733 CH3S CH3CH3H OH SB734 CH3SO CH3CH3H OH SB735 CH3SO2CH3CH3H OH SB736 Ph CH3CH3H OH SB737 CH3O CH3CH3H OH SB738 CH3CO2CH3CH3H OH SB739 CH3CH2CO2CH3CH3H OH SB740 CH2＝CHCH2CH3CH3H OH SB741 HCCCH2CH3CH3H OH SB742 CF3CH3CH3H OH SB743 (CH3)2NSO2CH3CH3H OH SB744 (CH3)2N CH3CH3H OH SB745 PhOCH3CH3H OH SB746 PhSCH3CH3H OH SB747 PhSO CH3CH3H OH SB748 PhSO2CH3CH3H OH SB749 CN CH3CH3H OH SB750 CH3CH3CH3CH3OH SB751 CH3CH2CH3CH3CH3OH SB752 CH3CH2CH2CH3CH3CH3OH SB753 (CH3)2CH CH3CH3CH3OH SB754 (CH3)3C CH3CH3CH3OH SB755 CH3S CH3CH3CH3OH SB756 CH3SO CH3CH3CH3OH SB757 CH3SO2CH3CH3CH3OH SB758 Ph CH3CH3CH3OH S基团 R44R37R38R39R40WB759 CH3O CH3CH3CH3OH SB760 CH3CO2CH3CH3CH3OH SB761 CH3CH2CO2CH3CH3CH3OH SB762 CH2＝CHCH2CH3CH3CH3OH SB763 HCCCH2CH3CH3CH3OH SB764 CF3CH3CH3CH3OH SB765 (CH3)2NSO2CH3CH3CH3OH SB766 (CH3)2NCH3CH3CH3OH SB767 PhO CH3CH3CH3OH SB768 PhS CH3CH3CH3OH SB769 PhSO CH3CH3CH3OH SB770 PhSO2CH3CH3CH3OH SB771 CNCH3CH3CH3OH SB772 CH3CH2CH3CH2H H OHSB773 CH3CH2CH2CH3CH2H H OH SB774 (CH3)2CH CH3CH2H H OH SB775 (CH3)3CCH3CH2H H OH SB776 CH3SCH3CH2H H OH SB777 CH3SO CH3CH2H H OH SB778 CH3SO2CH3CH2H H OH SB779 Ph CH3CH2H H OH SB780 CH3OCH3CH2H H OH SB781 CH3CO2CH3CH2H H OH SB782 CH3CH2CO2CH3CH2H H OH SB783 CH2＝CHCH2CH3CH2H H OH SB784 HCCCH2CH3CH2H H OH SB785 CF3CH3CH2H H OH SB786 (CH3)2NSO2CH3CH2H H OH SB787 (CH3)2N CH3CH2H H OH SB788 PhO CH3CH2H H OH SB789 PhS CH3CH2H H OH SB790 PhSO CH3CH2H H OH SB791 PhSO2CH3CH2H H OH S基团 R44R37R38R39R40WB792 CN CH3CH2H H OH SB793 H H H H OH SO2B794 CH3H H H OH SO2B795 CH3CH2H H H OH SO2B796 CH3CH2CH2H H H OH SO2B797 (CH3)2CH H H H OH SO2B798 (CH3)3C H H H OH SO2B799 CH3S H H H OH SO2B800 CH3SO H H H OH SO2B801 CH3SO2H H H OH SO2B802 Ph H H H OH SO2B803 CH3O H H H OH SO2B804 CH3CO2H H H OH SO2B805 CH3CH2CO2H H H OH SO2B806 CH2＝CHCH2H H H OH SO2B807 HCCCH2H H H OH SO2B808 CF3H H H OH SO2B809 (CH3)2NSO2H H H OH SO2B810 (CH3)2N H H H OH SO2B811 PhOH H H OH SO2B812 PhSH H H OH SO2B813 PhSO H H H OH SO2B814 PhSO2H H H OH SO2B815 CN H H H OH SO2B816 CH3CH3H H OH SO2B817 CH3CH2CH3H H OH SO2B818 CH3CH2CH2CH3H H OH SO2B819 (CH3)2CH CH3H H OH SO2B820 (CH3)3C CH3H H OH SO2B821 CH3S CH3H H OH SO2B822 CH3SO CH3H H OH SO2B823 CH3SO2CH3H H OH SO2B824 Ph CH3H H OH SO2基团 R44R37R38R39R40WB825 CH3O CH3HH OH SO2B826 CH3CO2CH3HH OH SO2B827 CH3CH2CO2CH3HH OH SO2B828 CH2＝CHCH2CH3HH OH SO2B829 HCCCH2CH3HH OH SO2B830 CF3CH3HH OH SO2B831 (CH3)2NSO2CH3HH OH SO2B832 (CH3)2N CH3HH OH SO2B833 PhO CH3HH OH SO2B834 PhS CH3HH OH SO2B835 PhSOCH3HH OH SO2B836 PhSO2CH3HH OH SO2B837 CN CH3HH OH SO2B838 CH3H CH3H OH SO2B839 CH3CH2H CH3H OH SO2B840 CH3CH2CH2H CH3H OH SO2B841 (CH3)2CH H CH3H OH SO2B842 (CH3)3C H CH3H OH SO2B843 CH3S H CH3H OH SO2B844 CH3SO H CH3H OH SO2B845 CH3SO2H CH3H OH SO2B846 Ph H CH3H OH SO2B847 CH3O H CH3H OH SO2B848 CH3CO2H CH3H OH SO2B849 CH3CH2CO2H CH3H OH SO2B850 CH2＝CHCH2H CH3H OH SO2B851 HCCCH2H CH3H OH SO2B852 CF3H CH3H OH SO2B853 (CH3)2NSO2H CH3H OH SO2B854 (CH3)2N H CH3H OH SO2B855 PhO H CH3H OH SO2B856 PhS H CH3H OH SO2B857 PhSOH CH3H OH SO2基团 R44R37R38R39R40WB858 PhSO2H CH3H OH SO2B859 CN H CH3H OH SO2B860 CH3CH3CH3H OH SO2B861 CH3CH2CH3CH3H OH SO2B862 CH3CH2CH2CH3CH3H OH SO2B863 (CH3)2CH CH3CH3H OH SO2B864 (CH3)3C CH3CH3H OH SO2B865 CH3S CH3CH3H OH SO2B866 CH3SO CH3CH3H OH SO2B867 CH3SO2CH3CH3H OH SO2B868 Ph CH3CH3H OH SO2B869 CH3O CH3CH3H OH SO2B870 CH3CO2CH3CH3H OH SO2B871 CH3CH2CO2CH3CH3H OH SO2B872 CH2＝CHCH2CH3CH3H OH SO2B873 HCCCH2CH3CH3H OH SO2B874 CF3CH3CH3H OH SO2B875 (CH3)2NSO2CH3CH3H OH SO2B876 (CH3)2N CH3CH3H OH SO2B877 PhOCH3CH3H OH SO2B878 PhSCH3CH3H OH SO2B879 PhSO CH3CH3H OH SO2B880 PhSO2CH3CH3H OH SO2B881 CN CH3CH3H OH SO2B882 CH3CH3CH3CH3OH SO2B883 CH3CH2CH3CH3CH3OH SO2B884 CH3CH2CH2CH3CH3CH3OH SO2B885 (CH3)2CH CH3CH3CH3OH SO2B886 (CH3)3C CH3CH3CH3OH SO2B887 CH3S CH3CH3CH3OH SO2B888 CH3SO CH3CH3CH3OH SO2B889 CH3SO2CH3CH3CH3OH SO2B890 Ph CH3CH3CH3OH SO2基团 R44R37R38R39R40WB891 CH3OCH3CH3CH3OH SO2B892 CH3CO2CH3CH3CH3OH SO2B893 CH3CH2CO2CH3CH3CH3OH SO2B894 CH2＝CHCH2CH3CH3CH3OH SO2B895 HCCCH2CH3CH3CH3OH SO2B896 CF3CH3CH3CH3OH SO2B897 (CH3)2NSO2CH3CH3CH3OH SO2B898 (CH3)2NCH3CH3CH3OH SO2B899 PhO CH3CH3CH3OH SO2B900 PhS CH3CH3CH3OH SO2B901 PhSO CH3CH3CH3OH SO2B902 PhSO2CH3CH3CH3OH SO2B903 CNCH3CH3CH3OH SO2B904 CH3CH2CH3CH2H H OH SO2B905 CH3CH2CH2CH3CH2H H OH SO2B906 (CH3)2CH CH3CH2H H OH SO2B907 (CH3)3CCH3CH2H H OH SO2B908 CH3SCH3CH2H H OH SO2B909 CH3SO CH3CH2H H OH SO2B910 CH3SO2CH3CH2H H OH SO2B911 Ph CH3CH2H H OH SO2B912 CH3OCH3CH2H H OH SO2B913 CH3CO2CH3CH2H H OH SO2B914 CH3CH2CO2CH3CH2H H OH SO2B915 CH2＝CHCH2CH3CH2H H OH SO2B916 HCCCH2CH3CH2H H OH SO2B917 CF3CH3CH2H H OH SO2B918 (CH3)2NSO2CH3CH2H H OH SO2B919 (CH3)2N CH3CH2H H OH SO2B920 PhO CH3CH2H H OH SO2B921 PhS CH3CH2H H OH SO2B922 PhSO CH3CH2H H OH SO2B923 PhSO2CH3CH2H H OH SO2基团 R44R37R38R39R40WB924 CN CH3CH2HHOH SO2B925 H H HHOH CH(CO2CH2CH3)B926 CH3H HHOH CH(CO2CH2CH3)B927 CH3CH2H HHOH CH(CO2CH2CH3)B928 CH3CH2CH2H HHOH CH(CO2CH2CH3)B929 (CH3)2CH H HHOH CH(CO2CH2CH3)B930 (CH3)3C H HHOH CH(CO2CH2CH3)B931 CH3S H HHOH CH(CO2CH2CH3)B932 CH3SO H HHOH CH(CO2CH2CH3)B933 CH3SO2H HHOH CH(CO2CH2CH3)B934 Ph H HHOH CH(CO2CH2CH3)B935 CH3O H HHOH CH(CO2CH2CH3)B936 CH3CO2H HHOH CH(CO2CH2CH3)B937 CH3CH2CO2H HHOH CH(CO2CH2CH3)B938 CH2＝CHCH2H HHOH CH(CO2CH2CH3)B939 HCCCH2H HHOH CH(CO2CH2CH3)B940 CF3H HHOH CH(CO2CH2CH3)B941 (CH3)2NSO2H HHOH CH(CO2CH2CH3)B942 (CH3)2N H HHOH CH(CO2CH2CH3)B943 PhOH HHOH CH(CO2CH2CH3)B944 PhSH HHOH CH(CO2CH2CH3)B945 PhSO H HHOH CH(CO2CH2CH3)B946 PhSO2H HHOH CH(CO2CH2CH3)B947 CN H HHOH CH(CO2CH2CH3)B948 CH3CH3HHOH CH(CO2CH2CH3)B949 CH3CH2CH3HHOH CH(CO2CH2CH3)B950 CH3CH2CH2CH3HHOH CH(CO2CH2CH3)B951 (CH3)2CH CH3HHOH CH(CO2CH2CH3)B952 (CH3)3C CH3HHOH CH(CO2CH2CH3)B953 CH3S CH3HHOH CH(CO2CH2CH3)B954 CH3SO CH3HHOH CH(CO2CH2CH3)B955 CH3SO2CH3HHOH CH(CO2CH2CH3)B956 Ph CH3HHOH CH(CO2CH2CH3)基团R44R37R38R39R40WB957CH3O CH3H H OH CH(CO2CH2CH3)B958CH3CO2CH3H H OH CH(CO2CH2CH3)B959CH3CH2CO2CH3H H OH CH(CO2CH2CH3)B960CH2＝CHCH2CH3H H OH CH(CO2CH2CH3)B961HCCCH2CH3H H OH CH(CO2CH2CH3)B962CF3CH3H H OH CH(CO2CH2CH3)B963(CH3)2NSO2CH3H H OH CH(CO2CH2CH3)B964(CH3)2N CH3H H OH CH(CO2CH2CH3)B965PhO CH3H H OH CH(CO2CH2CH3)B966PhS CH3H H OH CH(CO2CH2CH3)B967PhSOCH3H H OH CH(CO2CH2CH3)B968PhSO2CH3H H OH CH(CO2CH2CH3)B969CN CH3H H OH CH(CO2CH2CH3)B970CH3H CH3H OH CH(CO2CH2CH3)B971CH3CH2H CH3H OH CH(CO2CH2CH3)B972CH3CH2CH2H CH3H OH CH(CO2CH2CH3)B973(CH3)2CH H CH3H OH CH(CO2CH2CH3)B974(CH3)3C H CH3H OH CH(CO2CH2CH3)B975CH3S H CH3H OH CH(CO2CH2CH3)B976CH3SO H CH3H OH CH(CO2CH2CH3)B977CH3SO2H CH3H OH CH(CO2CH2CH3)B978Ph H CH3H OH CH(CO2CH2CH3)B979CH3O H CH3H OH CH(CO2CH2CH3)B980CH3CO2H CH3H OH CH(CO2CH2CH3)B981CH3CH2CO2H CH3H OH CH(CO2CH2CH3)B982CH2＝CHCH2H CH3H OH CH(CO2CH2CH3)B983HCCCH2H CH3H OH CH(CO2CH2CH3)B984CF3H CH3H OH CH(CO2CH2CH3)B985(CH3)2NSO2H CH3H OH CH(CO2CH2CH3)B986(CH3)2N H CH3H OH CH(CO2CH2CH3)B987PhO H CH3H OH CH(CO2CH2CH3)B988PhS H CH3H OH CH(CO2CH2CH3)B989PhSOH CH3H OH CH(CO2CH2CH3)基团R44R37R38R39R40WB990PhSO2HCH3H OH CH(CO2CH2CH3)B991CN HCH3H OH CH(CO2CH2CH3)B992CH3CH3CH3H OH CH(CO2CH2CH3)B993CH3CH2CH3CH3H OH CH(CO2CH2CH3)B994CH3CH2CH2CH3CH3H OH CH(CO2CH2CH3)B995(CH3)2CH CH3CH3H OH CH(CO2CH2CH3)B996(CH3)3C CH3CH3H OH CH(CO2CH2CH3)B997CH3S CH3CH3H OH CH(CO2CH2CH3)B998CH3SO CH3CH3H OH CH(CO2CH2CH3)B999CH3SO2CH3CH3H OH CH(CO2CH2CH3)B1000 Ph CH3CH3H OH CH(CO2CH2CH3)B1001 CH3O CH3CH3H OH CH(CO2CH2CH3)B1002 CH3CO2CH3CH3H OH CH(CO2CH2CH3)B1003 CH3CH2CO2CH3CH3H OH CH(CO2CH2CH3)B1004 CH2＝CHCH2CH3CH3H OH CH(CO2CH2CH3)B1005 HCCCH2CH3CH3H OH CH(CO2CH2CH3)B1006 CF3CH3CH3H OH CH(CO2CH2CH3)B1007 (CH3)2NSO2CH3CH3H OH CH(CO2CH2CH3)B1008 (CH3)2N CH3CH3H OH CH(CO2CH2CH3)B1009 PhO CH3CH3H OH CH(CO2CH2CH3)B1010 PhS CH3CH3H OH CH(CO2CH2CH3)B1011 PhSOCH3CH3H OH CH(CO2CH2CH3)B1012 PhSO2CH3CH3H OH CH(CO2CH2CH3)B1013 CN CH3CH3H OH CH(CO2CH2CH3)B1014 CH3CH3CH3CH3OH CH(CO2CH2CH3)B1015 CH3CH2CH3CH3CH3OH CH(CO2CH2CH3)B1016 CH3CH2CH2CH3CH3CH3OH CH(CO2CH2CH3)B1017 (CH3)2CH CH3CH3CH3OH CH(CO2CH2CH3)B1018 (CH3)3C CH3CH3CH3OH CH(CO2CH2CH3)B1019 CH3S CH3CH3CH3OH CH(CO2CH2CH3)B1020 CH3SO CH3CH3CH3OH CH(CO2CH2CH3)B1021 CH3SO2CH3CH3CH3OH CH(CO2CH2CH3)B1022 Ph CH3CH3CH3OH CH(CO2CH2CH3)基团R44R37R38R39R40WB1023 CH3O CH3CH3CH3OH CH(CO2CH2CH3)B1024 CH3CO2CH3CH3CH3OH CH(CO2CH2CH3)B1025 CH3CH2CO2CH3CH3CH3OH CH(CO2CH2CH3)B1026 CH2＝CHCH2CH3CH3CH3OH CH(CO2CH2CH3)B1027 HCCCH2CH3CH3CH3OH CH(CO2CH2CH3)B1028 CF3CH3CH3CH3OH CH(CO2CH2CH3)B1029 (CH3)2NSO2CH3CH3CH3OH CH(CO2CH2CH3)B1030 (CH3)2N CH3CH3CH3OH CH(CO2CH2CH3)B1031 PhO CH3CH3CH3OH CH(CO2CH2CH3)B1032 PhS CH3CH3CH3OH CH(CO2CH2CH3)B1033 PhSO CH3CH3CH3OH CH(CO2CH2CH3)B1034 PhSO2CH3CH3CH3OH CH(CO2CH2CH3)B1035 CN CH3CH3CH3OH CH(CO2CH2CH3)B1036 CH3CH2CH3CH2H H OH CH(CO2CH2CH3)B1037 CH3CH2CH2CH3CH2H H OH CH(CO2CH2CH3)B1038 (CH3)2CH CH3CH2H H OH CH(CO2CH2CH3)B1039 (CH3)3C CH3CH2H H OH CH(CO2CH2CH3)B1040 CH3S CH3CH2H H OH CH(CO2CH2CH3)B1041 CH3SO CH3CH2H H OH CH(CO2CH2CH3)B1042 CH3SO2CH3CH2H H OH CH(CO2CH2CH3)B1043 Ph CH3CH2H H OH CH(CO2CH2CH3)B1044 CH3O CH3CH2H H OH CH(CO2CH2CH3)B1045 CH3CO2CH3CH2H H OH CH(CO2CH2CH3)B1046 CH3CH2CO2CH3CH2H H OH CH(CO2CH2CH3)B1047 CH2＝CHCH2CH3CH2H H OH CH(CO2CH2CH3)B1048 HCCCH2CH3CH2H H OH CH(CO2CH2CH3)B1049 CF3CH3CH2H H OH CH(CO2CH2CH3)B1050 (CH3)2NSO2CH3CH2H H OH CH(CO2CH2CH3)B1051 (CH3)2N CH3CH2H H OH CH(CO2CH2CH3)B1052 PhO CH3CH2H H OH CH(CO2CH2CH3)B1053 PhS CH3CH2H H OH CH(CO2CH2CH3)B1054 PhSOCH3CH2H H OH CH(CO2CH2CH3)B1055 PhSO2CH3CH2H H OH CH(CO2CH2CH3)基团R44R37R38R39R40WB1056 CN CH3CH2H H OH CH(CO2CH2CH3)B1057 CH3OCOH H H OH CHPhB1058 H H H H OH CHPhB1059 H H H H OH CH(CH2CH3)B1060 H H H H OH CH(CH2CH2CH3)B1061 H H H H OH CH(CH(CH3)2)B1062 H H H H OH CH(C(CH3)3)B1063 H H H H OH C(CH3)2B1064 H H H H OH CH(CF3)B1065 CH3OCOH H H OH C(CH3)(CF3)B1066 H H H H OH C(CH3)(CF3)B1067 CH3OCOCH3O H H OH CH2B1068 H CH3O H H OH CH2B1069 CH3O CH3OCOH CH3OH CH2B1070 CH3O H CH3H OH CH2B1071 Cl H H H OH CH2B1072 F H H H OH CH2B1073 H H H H OH CH(OCH3)2B1074 H H H H OH CH2OSO2CH3B1075 CH3CH3CH3CH3OH S(O)B1076 ClCH2CH2H H H OH CH2B1077 HO(CH2)2H H H OH CH2B1078 MsO(CH2)2H H H OH CH2B1079 HOCH(CH3)CH2H H H OH CH2B1080 MsOCH(CH3)CH2H H H OH CH2B1081 (CH3)2CH H CH3CH3OH CH2B1082 HCCCH2H CH3CH3OH CH2B1083 H2C＝CCH2H CH3CH3OH CH2在下表7中，Q是Q6 且Q6代表下列基团C表7基团C基团 R84R85R86R83p WC1H H H OH 1 CH2C2CH3H H OH 1 CH2C3CH3CH2H H OH 1 CH2C4CH3CH2CH2H H OH 1 CH2C5(CH3)2CH H H OH 1 CH2C6(CH3)3C H H OH 1 CH2C7CH3SH H OH 1 CH2C8CH3SO H H OH 1 CH2C9CH3SO2H H OH 1 CH2C10 Ph H H OH 1 CH2C11 CH3OH H OH 1 CH2C12 CH3OCO2H H OH 1 CH2C13 CH3CH2OCO2H H OH 1 CH2C14 CH2＝CHCH2H H OH 1 CH2C15 HCCCH2H H OH 1 CH2C16 CF3H H OH 1 CH2C17 (CH3)2NSO2H H OH 1 CH2C18 (CH3)2N H H OH 1 CH2C19 PhO H H OH 1 CH2C20 PhS H H OH 1 CH2C21 PhSOH H OH 1 CH2C22 PhSO2H H OH 1 CH2基团 R84R85R86R83pWC23 CN H H OH 1CH2C24 CH3CH3H OH 1CH2C25 CH3CH2CH3H OH 1CH2C26 CH3CH2CH2CH3H OH 1CH2C27 (CH3)2CH CH3H OH 1CH2C28 (CH3)3CCH3H OH 1CH2C29 CH3SCH3H OH 1CH2C30 CH3SO CH3H OH 1CH2C31 CH3SO2CH3H OH 1CH2C32 Ph CH3H OH 1CH2C33 CH3OCH3H OH 1CH2C34 CH3OCO2CH3H OH 1CH2C35 CH3CH2OCO2CH3H OH 1CH2C36 CH2＝CHCH2CH3H OH 1CH2C37 HCCCH2CH3H OH 1CH2C38 CF3CH3H OH 1CH2C39 (CH3)2NSO2CH3H OH 1CH2C40 (CH3)2N CH3H OH 1CH2C41 PhO CH3H OH 1CH2C42 PhS CH3H OH 1CH2C43 PhSO CH3H OH 1CH2C44 PhSO2CH3H OH 1CH2C45 CN CH3H OH 1CH2C46 HH H OH 4CH2C47 CH3H H OH 4CH2C48 CH3CH2H H OH 4CH2C49 CH3CH2CH2H H OH 4CH2C50 (CH3)2CH H H OH 4CH2C51 (CH3)3CH H OH 4CH2C52 CH3SH H OH 4CH2C53 CH3SO H H OH 4CH2C54 CH3SO2H H OH 4CH2C55 Ph H H OH 4CH2基团 R84R85R86R83pWC56 CH3OH H OH 4CH2C57 CH3OCO2H H OH 4CH2C58 CH3CH2OCO2H H OH 4CH2C59 CH2＝CHCH2H H OH 4CH2C60 HCCCH2H H OH 4CH2C61 CF3H H OH 4CH2C62 (CH3)2NSO2H H OH 4CH2C63 (CH3)2N H H OH 4CH2C64 PhO H H OH 4CH2C65 PhS H H OH 4CH2C66 PhSO H H OH 4CH2C67 PhSO2H H OH 4CH2C68 CN H H OH 4CH2C69 CH3CH3H OH 4CH2C70 CH3CH2CH3H OH 4CH2C71 CH3CH2CH2CH3H OH 4CH2C72 (CH3)2CH CH3H OH 4CH2C73 (CH3)3CCH3H OH 4CH2C74 CH3SCH3H OH 4CH2C75 CH3SO CH3H OH 4CH2C76 CH3SO2CH3H OH 4CH2C77 Ph CH3H OH 4CH2C78 CH3OCH3H OH 4CH2C79 CH3OCO2CH3H OH 4CH2C80 CH3CH2OCO2CH3H OH 4CH2C81 CH2＝CHCH2CH3H OH 4CH2C82 HCCCH2CH3H OH 4CH2C83 CF3CH3H OH 4CH2C84 (CH3)2NSO2CH3H OH 4CH2C85 (CH3)2N CH3H OH 4CH2C86 PhO CH3H OH 4CH2C87 PhS CH3H OH 4CH2C88 PhSO CH3H OH 4CH2基团 R84R85R86R83p WC89 PhSO2CH3H OH 4 CH2C90 CN CH3H OH 4 CH2C91 H H H OH 3 CH2C92 CH3H H OH 3 CH2C93 CH3CH2H H OH 3 CH2C94 CH3CH2CH2H H OH 3 CH2C95 (CH3)2CH H H OH 3 CH2C96 (CH3)3C H H OH 3 CH2C97CH3S H H OH 3 CH2C98CH3SOH H OH 3 CH2C99CH3SO2H H OH 3 CH2C100 PhH H OH 3 CH2C101 CH3O H H OH 3 CH2C102 CH3OCO2H H OH 3 CH2C103 CH3CH2OCO2H H OH 3 CH2C104 CH2＝CHCH2H H OH 3 CH2C105 HCCCH2H H OH 3 CH2C106 CF3H H OH 3 CH2C107 (CH3)2NSO2H H OH 3 CH2C108 (CH3)2N H H OH 3 CH2C109 PhO H H OH 3 CH2C110 PhS H H OH 3 CH2C111 PhSO H H OH 3 CH2C112 PhSO2H H OH 3 CH2C113 CNH H OH 3 CH2C114 CH3CH3H OH 3 CH2C115 CH3CH2CH3H OH 3 CH2C116 CH3CH2CH2CH3H OH 3 CH2C117 (CH3)2CHCH3H OH 3 CH2C118 (CH3)3C CH3H OH 3 CH2C119 CH3S CH3H OH 3 CH2C120 CH3SOCH3H OH 3 CH2C121 CH3SO2CH3H OH 3 CH2基团 R84R85R86R83p WC122 PhCH3H OH 3 CH2C123 CH3O CH3H OH 3 CH2C124 CH3OCO2CH3H OH 3 CH2C125 CH3CH2OCO2CH3H OH 3 CH2C126 CH2＝CHCH2CH3H OH 3 CH2C127 HCCCH2CH3H OH 3 CH2C128 CF3CH3H OH 3 CH2C129 (CH3)2NSO2CH3H OH 3 CH2C130 (CH3)2N CH3H OH 3 CH2C131 PhO CH3H OH 3 CH2C132 PhS CH3H OH 3 CH2C133 PhSO CH3H OH 3 CH2C134 PhSO2CH3H OH 3 CH2C135 CNCH3H OH 3 CH2C136 CH3CH2CH3CH2H OH 1 CH2C137 H H H OH 1 CH(CH3)C138 CH3H H OH 1 CH(CH3)C139 CH3CH3H OH 1 CH(CH3)C140 CH2CH3H H OH 1 CH(CH3)C141 CH2CH3CH3H OH 1 CH(CH3)C142 CH3CH2CH3CH2H OH 1 CH(CH3)C143 H H CH3OH 1 CH2C144 CH3CH3CH3OH 1 CH2C145 CH3CH2CH3CH2CH3OH 1 CH2C146 H H H OH 2 CH2C147 CH3CH3H OH 2 CH2C148 CH3CH2CH3CH2H OH 2 CH2C149 H H H OH 5 CH2C150 CH3CH3H OH 5 CH2C151 CH3CH2CH3CH2H OH 5 CH2在下表8中，Q是Q8 且Q8代表下列基团D表8基团D基团 R88R89R90R91R87oD1H H H H OH 2D2CH3H H H OH 2D3CH3CH2H H H OH 2D4CH3CH2CH2H H H OH 2D5(CH3)2CH H H H OH 2D6(CH3)3C H H H OH 2D7CH3S H H H OH 2D8CH3SO H H H OH 2D9CH3SO2H H H OH 2D10 Ph H H H OH 2D11 CH3O H H H OH 2D12 CH2＝CHCH2H H H OH 2D13 HCCCH2H H H OH 2D14 CF3H H H OH 2D15 PhOH H H OH 2D16 PhSH H H OH 2D17 PhSO H H H OH 2D18 PhSO2H H H OH 2D19 CH3CH3H H OH 2D20 CH3CH2CH3H H OH 2D21 CH3CH2CH2CH3H H OH 2D22 (CH3)2CH CH3H H OH 2D23 (CH3)3C CH3H H OH 2基团 R88R89R90R91R87oD24CH3S CH3H H OH 2D25CH3SO CH3H H OH 2D26CH3SO2CH3H H OH 2D27Ph CH3H H OH 2D28CH3O CH3H H OH 2D29CH2＝CHCH2CH3H H OH 2D30HCCCH2CH3H H OH 2D31CF3CH3H H OH 2D32PhO CH3H H OH 2D33PhS CH3H H OH 2D34PhSOCH3H H OH 2D35PhSO2CH3H H OH 2D36H HH H OH 3D37CH3HH H OH 3D38CH3CH2HH H OH 3D39CH3CH2CH2HH H OH 3D40(CH3)2CH HH H OH 3D41(CH3)3C HH H OH 3D42CH3S HH H OH 3D43CH3SO HH H OH 3D44CH3SO2HH H OH 3D45Ph HH H OH 3D46CH3O HH H OH 3D47CH2＝CHCH2HH H OH 3D48HCCCH2HH H OH 3D49CF3HH H OH 3D50PhO HH H OH 3D51PhS HH H OH 3D52PhSOHH H OH 3D53PhSO2HH H OH 3D54CH3CH3H H OH 3D55CH3CH2CH3H H OH 3D56CH3CH2CH2CH3H H OH 3基团 R88R89R90R91R87oD57(CH3)2CH CH3H H OH 3D58(CH3)3C CH3H H OH 3D59CH3S CH3H H OH 3D60CH3SO CH3H H OH 3D61CH3SO2CH3H H OH 3D62Ph CH3H H OH 3D63CH3O CH3H H OH 3D64CH2＝CHCH2CH3H H OH 3D65HCCCH2CH3H H OH 3D66CF3CH3H H OH 3D67PhO CH3H H OH 3D68PhS CH3H H OH 3D69PhSOCH3H H OH 3D70PhSO2CH3H H OH 3D71H H H H OH 4D72CH3H H H OH 4D73CH3CH2H H H OH 4D74CH3CH2CH2H H H OH 4D75(CH3)2CH H H H OH 4D76(CH3)3C H H H OH 4D77CH3S H H H OH 4D78CH3SO H H H OH 4D79CH3SO2H H H OH 4D80Ph H H H OH 4D81CH3O H H H OH 4D82CH2＝CHCH2H H H OH 4D83HCCCH2H H H OH 4D84CF3H H H OH 4D85PhO H H H OH 4D86PhS H H H OH 4D87PhSOH H H OH 4D88PhSO2H H H OH 4D89CH3CH3H H OH 4基团 R88R89R90R91R87oD90CH3CH2CH3H H OH 4D91CH3CH2CH2CH3H H OH 4D92(CH3)2CHCH3H H OH 4D93(CH3)3C CH3H H OH 4D94CH3S CH3H H OH 4D95CH3SOCH3H H OH 4D96CH3SO2CH3H H OH 4D97PhCH3H H OH 4D98CH3O CH3H H OH 4D99CH2＝CHCH2CH3H H OH 4D100 HCCCH2CH3H H OH 4D101 CF3CH3H H OH 4D102 PhO CH3H H OH 4D103 PhS CH3H H OH 4D104 PhSO CH3H H OH 4D105 PhSO2CH3H H OH 4D106 H H H CH3OH 4D107 H H H CH3OH 3D108 H H H H OH 1D109 CH3H H H OH 1D110 CH3OCO CH3H H OH 1D111 CH3CH2OCO CH3H H OH 1D112 CH3O CH3H H OH 1D113 CH3S CH3H H OH 1D114 CH3SOCH3H H OH 1D115 CH3SO2CH3H H OH 1D116 CH3CH2H H H OH 1D117 CH3OCO CH3CH2H H OH 1D118 CH3CH2OCO CH3CH2H H OH 1D119 CH3O CH3CH2H H OH 1D120 CH3S CH3CH2H H OH 1D121 CH3SOCH3CH2H H OH 1D122 CH3SO2CH3CH2H H OH 1基团R88R89R90R91R87oD123CH3CH2SCH3HH OH 1D124CH3CH2SO CH3HH OH 1D125CH3CH2SO2CH3HH OH 1D126CH3CH2SCH3CH2HH OH 1D127CH3CH2SO CH3CH2HH OH 1D128CH3CH2SO2CH3CH2HH OH 1D129H H CH3H OH 1D130CH3H CH3H OH 1D131CH3OCO CH3CH3H OH 1D132CH3CH2OCO CH3CH3H OH 1D133CH3O CH3CH3H OH 1D134CH3S CH3CH3H OH 1D135CH3SOCH3CH3H OH 1D136CH3SO2CH3CH3H OH 1D137H H HCH3OH 1D138CH3H HCH3OH 1D139H H CH3CH3OH 1D140CH3CH2OCO CH3HH OH 4表9式If化合物 化合物. R92R93R94R95Q3序号A1 H H HCF3B24A2 CH3H HCF3B24A3 CH3CH2H HCF3B24化合物 R92R93R94R95Q3序号A4 (CH3)2CH H H CF3B24A5 (CH3)3C H H CF3B24A6 环丙基 H H CF3B24A7 CH3(CH2)2H H CF3B24A8 CH3OCH2H H CF3B24A9 CH3O(CH2)2H H CF3B24A10 Ph H H CF3B24A11 PhO H H CF3B24A12 PhS H H CF3B24A13 PhSOH H CF3B24A14 PhSO2H H CF3B24A15 CH3S H H CF3B24A16 CH3SO H H CF3B24A17 CF3H H CF3B24A18 F2CH H H CF3B24A19 HCC H H CF3B24A20 CH3CC H H CF3B24A21 CH2＝CHH H CF3B24A22 CH2＝CHCH2H H CF3B24A23 CH3SO2N(CH3) H H CF3B24A24 (CH3)2N H H CF3B24A25 (CH3)2NSO2H H CF3B24A26 ClCH2H H CF3B24A27 CH3SCH2H H CF3B24A28 CH3SOCH2H H CF3B24A29 CH3SO2CH2H H CF3B24A30 [1，2，4]-三唑-1-基-甲基 H H CF3B24A31 CH3CF3H CH3B24A32 CH3CH3H CF3B24A33 H H H CF3CF2B24A34 CH3H H CF3CF2B24A35 CH3CH2H H CF3CF2B24化合物 R92R93R94R95Q3序号A36环丙基 H H CF3CF2B24A37(CH3)3C H H CF3CF2B24A38(CH3)2CH H H CF3CF2B24A39CH3(CH2)2H H CF3CF2B24A40CH3OCH2H H CF3CF2B24A41CH3O(CH2)2H H CF3CF2B24A42Ph H H CF3CF2B24A43PhO H H CF3CF2B24A44PhS H H CF3CF2B24A45PhSOH H CF3CF2B24A46PhSO2H H CF3CF2B24A47CH3S H H CF3CF2B24A48CH3SO H H CF3CF2B24A49CF3H H CF3CF2B24A50F2CH H H CF3CF2B24A51HCC H H CF3CF2B24A52CH3CC H H CF3CF2B24A53CH2＝CHH H CF3CF2B24A54CH2＝CHCH2H H CF3CF2B24A55CH3SO2N(CH3) H H CF3CF2B24A56(CH3)2N H H CF3CF2B24A57(CH3)2NSO2H H CF3CF2B24A58ClCH2H H CF3CF2B24A59CH3SCH2H H CF3CF2B24A60CH3SOCH2H H CF3CF2B24A61CH3SO2CH2H H CF3CF2B24A62[1，2，4]-三唑-1-基-甲基H H CF3CF2B24A63H H H CF3CF2CF2B24A64CH3H H CF3CF2CF2B24A65CH3CH2H H CF3CF2CF2B24A66环丙基 H H CF3CF2CF2B24A67(CH3)3C H H CF3CF2CF2B24化合物R92R93R94R95Q3序号A68 (CH3)2CH HHCF3CF2CF2B24A69 CH3(CH2)2HHCF3CF2CF2B24A70 CH3OCH2HHCF3CF2CF2B24A71 CH3O(CH2)2HHCF3CF2CF2B24A72 Ph HHCF3CF2CF2B24A73 PhO HHCF3CF2CF2B24A74 PhS HHCF3CF2CF2B24A75 PhSOHHCF3CF2CF2B24A76 PhSO2HHCF3CF2CF2B24A77 CH3S HHCF3CF2CF2B24A78 CH3SO HHCF3CF2CF2B24A79 CF3HHCF3CF2CF2B24A80 F2CH HHCF3CF2CF2B24A81 HCC HHCF3CF2CF2B24A82 CH3CC HHCF3CF2CF2B24A83 CH2＝CHHHCF3CF2CF2B24A84 CH2＝CHCH2HHCF3CF2CF2B24A85 CH3SO2N(CH3) HHCF3CF2CF2B24A86 (CH3)2N HHCF3CF2CF2B24A87 (CH3)2NSO2HHCF3CF2CF2B24A88 ClCH2HHCF3CF2CF2B24A89 CH3SCH2HHCF3CF2CF2B24A90 CH3SOCH2HHCF3CF2CF2B24A91 CH3SO2CH2HHCF3CF2CF2B24A92 [1，2，4]-三唑-1-基-甲基HHCF3CF2CF2B24A93 H HHCF2Cl B24A94 CH3HHCF2Cl B24A95 CH3CH2HHCF2Cl B24A96 环丙基 HHCF2Cl B24A97 (CH3)3C HHCF2Cl B24A98 (CH3)2CH HHCF2Cl B24A99 CH3(CH2)2HHCF2Cl B24化合物 R92R93R94R95Q3序号A100CH3OCH2H H CF2Cl B24A101CH3O(CH2)2H H CF2Cl B24A102Ph H H CF2Cl B24A103PhO H H CF2Cl B24A104PhS H H CF2Cl B24A105PhSOH H CF2Cl B24A106PhSO2H H CF2Cl B24A107CH3S H H CF2Cl B24A108CH3SO H H CF2Cl B24A109CF3H H CF2Cl B24A110F2CH H H CF2Cl B24A111HCC H H CF2Cl B24A112CH3CC H H CF2Cl B24A113CH2＝CHH H CF2Cl B24A114CH2＝CHCH2H H CF2Cl B24A115CH3SO2N(CH3) H H CF2Cl B24A116(CH3)2N H H CF2Cl B24A117(CH3)2NSO2H H CF2Cl B24A118ClCH2H H CF2Cl B24A119CH3SCH2H H CF2Cl B24A120CH3SOCH2H H CF2Cl B24A121CH3SO2CH2H H CF2Cl B24A122[1，2，4]-三唑-1-基-甲基H H CF2Cl B24A123H H H CHF2B24A124CH3H H CHF2B24A125CH3CH2H H CHF2B24A126环丙基 H H CHF2B24A127(CH3)3C H H CHF2B24A128(CH3)2CH H H CHF2B24A129CH3(CH2)2H H CHF2B24A130CH3OCH2H H CHF2B24A131CH3O(CH2)2H H CHF2B24化合物 R92R93R94R95Q3序号A132Ph HHCHF2B24A133PhO HHCHF2B24A134PhS HHCHF2B24A135PhSOHHCHF2B24A136PhSO2HHCHF2B24A137CH3S HHCHF2B24A138CH3SO HHCHF2B24A139CF3HHCHF2B24A140F2CH HHCHF2B24A141HCC HHCHF2B24A142CH3CC HHCHF2B24A143CH2＝CHHHCHF2B24A144CH2＝CHCH2HHCHF2B24A145CH3SO2N(CH3) HHCHF2B24A146(CH3)2N HHCHF2B24A147(CH3)2NSO2HHCHF2B24A148ClCH2HHCHF2B24A149CH3SCH2HHCHF2B24A150CH3SOCH2HHCHF2B24A151CH3SO2CH2HHCHF2B24A152[1，2，4]-三唑-1-基-甲基HHCHF2B24A153H HHCCl3B24A154CH3HHCCl3B24A155CH3CH2HHCCl3B24A156环丙基 HHCCl3B24A157(CH3)3C HHCCl3B24A158(CH3)2CH HHCCl3B24A159CH3(CH2)2HHCCl3B24A160CH3OCH2HHCCl3B24A161CH3O(CH2)2HHCCl3B24A162Ph HHCCl3B24A163PhO HHCCl3B24化合物 R92R93R94R95Q3序号A164PhS H H CCl3B24A165PhSOH H CCl3B24A166PhSO2H H CCl3B24A167CH3S H H CCl3B24A168CH3SO H H CCl3B24A169CF3H H CCl3B24A170F2CH H H CCl3B24A171HCC H H CCl3B24A172CH3CC H H CCl3B24A173CH2＝CHH H CCl3B24A174CH2＝CHCH2H H CCl3B24A175CH3SO2N(CH3) H H CCl3B24A176(CH3)2N H H CCl3B24A177(CH3)2NSO2H H CCl3B24A178ClCH2H H CCl3B24A179CH3SCH2H H CCl3B24A180CH3SOCH2H H CCl3B24A181CH3SO2CH2H H CCl3B24A182[1，2，4]-三唑-1-基-甲基H H CCl3B24A183H H CH3CF3B24A184CH3H CH3CF3B24A185CH3CH2H CH3CF3B24A186环丙基 H CH3CF3B24A187(CH3)3C H CH3CF3B24A188(CH3)2CH H CH3CF3B24A189CH3(CH2)2H CH3CF3B24A190CH3OCH2H CH3CF3B24A191CH3O(CH2)2H CH3CF3B24A192Ph H CH3CF3B24A193PhO H CH3CF3B24A194PhS H CH3CF3B24A195PhSOH CH3CF3B24化合物 R92R93R94R95Q3序号A196 PhSO2H CH3CF3B24A197 CH3S H CH3CF3B24A198 CH3SOH CH3CF3B24A199 CF3H CH3CF3B24A200 F2CH H CH3CF3B24A201 HCC H CH3CF3B24A202 CH3CCH CH3CF3B24A203 CH2＝CH H CH3CF3B24A204 CH2＝CHCH2H CH3CF3B24A205 CH3SO2N(CH3) H CH3CF3B24A206 (CH3)2NH CH3CF3B24A207 (CH3)2NSO2H CH3CF3B24A208 ClCH2H CH3CF3B24A209 CH3SCH2H CH3CF3B24A210 CH3SOCH2H CH3CF3B24A211 CH3SO2CH2H CH3CF3B24A212 H H CH3CF3CF2B24A213 CH3H CH3CF3CF2B24A214 CH3CH2H CH3CF3CF2B24A215 环丙基H CH3CF3CF2B24A216 (CH3)3CH CH3CF3CF2B24A217 (CH3)2CH H CH3CF3CF2B24A218 CH3(CH2)2H CH3CF3CF2B24A219 CH3OCH2H CH3CF3CF2B24A220 CH3O(CH2)2H CH3CF3CF2B24A221 PhH CH3CF3CF2B24A222 PhO H CH3CF3CF2B24A223 PhS H CH3CF3CF2B24A224 PhSO H CH3CF3CF2B24A225 PhSO2H CH3CF3CF2B24A226 CH3S H CH3CF3CF2B24A227 CH3SOH CH3CF3CF2B24化合物 R92R93R94R95Q3序号A228 CF3H CH3CF3CF2B24A229 F2CH H CH3CF3CF2B24A230 HCCH CH3CF3CF2B24A231 CH3CC H CH3CF3CF2B24A232 CH2＝CH H CH3CF3CF2B24A233 CH2＝CHCH2H CH3CF3CF2B24A234 CH3SO2N(CH3) H CH3CF3CF2B24A235 (CH3)2N H CH3CF3CF2B24A236 (CH3)2NSO2H CH3CF3CF2B24A237 ClCH2H CH3CF3CF2B24A238 CH3SCH2H CH3CF3CF2B24A239 CH3SOCH2H CH3CF3CF2B24A240 CH3SO2CH2H CH3CF3CF2B24A241 H H CH3CF3CF2CF2B24A242 CH3H CH3CF3CF2CF2B24A243 CH3CH2H CH3CF3CF2CF2B24A244 环丙基 H CH3CF3CF2CF2B24A245 (CH3)3C H CH3CF3CF2CF2B24A246 (CH3)2CHH CH3CF3CF2CF2B24A247 CH3(CH2)2H CH3CF3CF2CF2B24A248 CH3OCH2H CH3CF3CF2CF2B24A249 CH3O(CH2)2H CH3CF3CF2CF2B24A250 Ph H CH3CF3CF2CF2B24A251 PhOH CH3CF3CF2CF2B24A252 PhSH CH3CF3CF2CF2B24A253 PhSO H CH3CF3CF2CF2B24A254 PhSO2H CH3CF3CF2CF2B24A255 CH3S H CH3CF3CF2CF2B24A256 CH3SO H CH3CF3CF2CF2B24A257 CF3H CH3CF3CF2CF2B24A258 F2CH H CH3CF3CF2CF2B24A259 HCCH CH3CF3CF2CF2B24化合物 R92R93R94R95Q3序号A260 CH3CC H CH3CF3CF2CF2B24A261 CH2＝CHH CH3CF3CF2CF2B24A262 CH2＝CHCH2H CH3CF3CF2CF2B24A263 CH3SO2N(CH3)H CH3CF3CF2CF2B24A264 (CH3)2N H CH3CF3CF2CF2B24A265 (CH3)2NSO2H CH3CF3CF2CF2B24A266 ClCH2H CH3CF3CF2CF2B24A267 CH3SCH2H CH3CF3CF2CF2B24A268 CH3SOCH2H CH3CF3CF2CF2B24A269 CH3SO2CH2H CH3CF3CF2CF2B24A270 H H CH3CF2ClB24A271 CH3H CH3CF2Cl B24A272 CH3CH2H CH3CF2Cl B24A273 环丙基 H CH3CF2Cl B24A274 (CH3)3C H CH3CF2Cl B24A275 (CH3)2CH H CH3CF2Cl B24A276 CH3(CH2)2H CH3CF2Cl B24A277 CH3OCH2H CH3CF2Cl B24A278 CH3O(CH2)2H CH3CF2Cl B24A279 Ph H CH3CF2Cl B24A280 PhO H CH3CF2Cl B24A281 PhS H CH3CF2Cl B24A282 PhSOH CH3CF2Cl B24A283 PhSO2H CH3CF2Cl B24A284 CH3S H CH3CF2Cl B24A285 CH3SO H CH3CF2Cl B24A286 CF3H CH3CF2Cl B24A287 F2CH H CH3CF2Cl B24A288 HCC H CH3CF2Cl B24A289 CH3CC H CH3CF2Cl B24A290 CH2＝CHH CH3CF2Cl B24A291 CH2＝CHCH2H CH3CF2Cl B24化合物 R92R93R94R95Q3序号A292 CH3SO2N(CH3) H CH3CF2Cl B24A293 (CH3)2N H CH3CF2Cl B24A294 (CH3)2NSO2H CH3CF2Cl B24A295 ClCH2H CH3CF2Cl B24A296 CH3SCH2H CH3CF2Cl B24A297 CH3SOCH2H CH3CF2Cl B24A298 CH3SO2CH2H CH3CF2Cl B24A299 H H CH3CHF2B24A300 CH3H CH3CHF2B24A301 CH3CH2H CH3CHF2B24A302 环丙基 H CH3CHF2B24A303 (CH3)3C H CH3CHF2B24A304 (CH3)2CHH CH3CHF2B24A305 CH3(CH2)2H CH3CHF2B24A306 CH3OCH2H CH3CHF2B24A307 CH3O(CH2)2H CH3CHF2B24A308 Ph H CH3CHF2B24A309 PhOH CH3CHF2B24A310 PhSH CH3CHF2B24A311 PhSO H CH3CHF2B24A312 PhSO2H CH3CHF2B24A313 CH3S H CH3CHF2B24A314 CH3SO H CH3CHF2B24A315 CF3H CH3CHF2B24A316 F2CH H CH3CHF2B24A317 HCCH CH3CHF2B24A318 CH3CC H CH3CHF2B24A319 CH2＝CH H CH3CHF2B24A320 CH2＝CHCH2H CH3CHF2B24A321 CH3SO2N(CH3) H CH3CHF2B24A322 (CH3)2N H CH3CHF2B24A323 (CH3)2NSO2H CH3CHF2B24化合物 R92R93R94R95Q3序号A324 ClCH2H CH3CHF2B24A325 CH3SCH2H CH3CHF2B24A326 CH3SOCH2H CH3CHF2B24A327 CH3SO2CH2H CH3CHF2B24A328 H H CH3CCl3B24A329 CH3H CH3CCl3B24A330 CH3CH2H CH3CCl3B24A331 (CH3)3CH CH3CCl3B24A332 (CH3)2CH H CH3CCl3B24A333 环丙基H CH3CCl3B24A334 CH3(CH2)2H CH3CCl3B24A335 CH3OCH2H CH3CCl3B24A336 CH3O(CH2)2H CH3CCl3B24A337 PhH CH3CCl3B24A338 PhO H CH3CCl3B24A339 PhS H CH3CCl3B24A340 PhSO H CH3CCl3B24A341 PhSO2H CH3CCl3B24A342 CH3S H CH3CCl3B24A343 CH3SOH CH3CCl3B24A344 CF3H CH3CCl3B24A345 F2CH H CH3CCl3B24A346 HCC H CH3CCl3B24A347 CH3CCH CH3CCl3B24A348 CH2＝CH H CH3CCl3B24A349 CH2＝CHCH2H CH3CCl3B24A350 CH3SO2N(CH3) H CH3CCl3B24A351 (CH3)2NH CH3CCl3B24A352 (CH3)2NSO2H CH3CCl3B24A353 ClCH2H CH3CCl3B24A354 CH3SCH2H CH3CCl3B24A355 CH3SOCH2H CH3CCl3B24化合物 R92R93R94R95Q3序号A356 CH3SO2CH2H CH3CCl3B24A357 H H Ph CF3B24A358 CH3H Ph CF3B24A359 CH3CH2H Ph CF3B24A360 环丙基 H Ph CF3B24A361 (CH3)3C H Ph CF3B24A362 (CH3)2CH H Ph CF3B24A363 CH3(CH2)2H Ph CF3B24A364 CH3OCH2H Ph CF3B24A365 CH3O(CH2)2H Ph CF3B24A366 Ph H Ph CF3B24A367 PhO H Ph CF3B24A368 PhS H Ph CF3B24A369 PhSOH Ph CF3B24A370 PhSO2H Ph CF3B24A371 CH3S H Ph CF3B24A372 CH3SO H Ph CF3B24A373 CF3H Ph CF3B24A374 F2CH H Ph CF3B24A375 HCC H Ph CF3B24A376 CH3CC H Ph CF3B24A377 CH2＝CHH Ph CF3B24A378 CH2＝CHCH2H Ph CF3B24A379 CH3SO2N(CH3) H Ph CF3B24A380 (CH3)2N H Ph CF3B24A381 (CH3)2NSO2H Ph CF3B24A382 ClCH2H Ph CF3B24A383 CH3SCH2H Ph CF3B24A384 CH3SOCH2H Ph CF3B24A385 CH3SO2CH2H Ph CF3B24A386 H H Ph CF3CF2B24A387 CH3H Ph CF3CF2B24化合物 R92R93R94R95Q3序号A388 CH3CH2H Ph CF3CF2B24A389 环丙基 H Ph CF3CF2B24A390 (CH3)3C H Ph CF3CF2B24A391 (CH3)2CH H Ph CF3CF2B24A392 CH3(CH2)2H Ph CF3CF2B24A393 CH3OCH2H Ph CF3CF2B24A394 CH3O(CH2)2H Ph CF3CF2B24A395 Ph H Ph CF3CF2B24A396 PhO H Ph CF3CF2B24A397 PhS H Ph CF3CF2B24A398 PhSOH Ph CF3CF2B24A399 PhSO2H Ph CF3CF2B24A400 CH3S H Ph CF3CF2B24A401 CH3SO H Ph CF3CF2B24A402 CF3H Ph CF3CF2B24A403 F2CH H Ph CF3CF2B24A404 HCC H Ph CF3CF2B24A405 CH3CC H Ph CF3CF2B24A406 CH2＝CHH Ph CF3CF2B24A407 CH2＝CHCH2H Ph CF3CF2B24A408 CH3SO2N(CH3) H Ph CF3CF2B24A409 (CH3)2N H Ph CF3CF2B24A41O (CH3)2NSO2H Ph CF3CF2B24A411 ClCH2H Ph CF3CF2B24A412 CH3SCH2H Ph CF3CF2B24A413 CH3SOCH2H Ph CF3CF2B24A414 CH3SO2CH2H Ph CF3CF2B24A415 H H Ph CF3CF2CF2B24A416 CH3H Ph CF3CF2CF2B24A417 CH3CH2H Ph CF3CF2CF2B24A418 环丙基 H Ph CF3CF2CF2B24A419 (CH3)3C H Ph CF3CF2CF2B24化合物 R92R93R94R95Q3序号A420 (CH3)2CH H Ph CF3CF2CF2B24A421 CH3(CH2)2H Ph CF3CF2CF2B24A422 CH3OCH2H Ph CF3CF2CF2B24A423 CH3O(CH2)2H Ph CF3CF2CF2B24A424 Ph H Ph CF3CF2CF2B24A425 PhO H Ph CF3CF2CF2B24A426 PhS H Ph CF3CF2CF2B24A427 PhSO H Ph CF3CF2CF2B24A428 PhSO2H Ph CF3CF2CF2B24A429 CH3SH Ph CF3CF2CF2B24A430 CH3SO H Ph CF3CF2CF2B24A431 CF3H Ph CF3CF2CF2B24A432 F2CHH Ph CF3CF2CF2B24A433 HCC H Ph CF3CF2CF2B24A434 CH3CC H Ph CF3CF2CF2B24A435 CH2＝CH H Ph CF3CF2CF2B24A436 CH2＝CHCH2H Ph CF3CF2CF2B24A437 CH3SO2N(CH3) H Ph CF3CF2CF2B24A438 (CH3)2N H Ph CF3CF2CF2B24A439 (CH3)2NSO2H Ph CF3CF2CF2B24A440 ClCH2H Ph CF3CF2CF2B24A441 CH3SCH2H Ph CF3CF2CF2B24A442 CH3SOCH2H Ph CF3CF2CF2B24A443 CH3SO2CH2H Ph CF3CF2CF2B24A444 HH Ph CF2Cl B24A445 CH3H Ph CF2Cl B24A446 CH3CH2H Ph CF2Cl B24A447 环丙基 H Ph CF2Cl B24A448 (CH3)3C H Ph CF2Cl B24A449 (CH3)2CH H Ph CF2Cl B24A450 CH3(CH2)2H Ph CF2Cl B24A451 CH3OCH2H Ph CF2Cl B24化合物 R92R93R94R95Q3序号A452 CH3O(CH2)2H Ph CF2Cl B24A453 Ph H Ph CF2Cl B24A454 PhO H Ph CF2Cl B24A455 PhS H Ph CF2Cl B24A456 PhSO H Ph CF2Cl B24A457 PhSO2H Ph CF2Cl B24A458 CH3SH Ph CF2Cl B24A459 CH3SO H Ph CF2Cl B24A460 CF3H Ph CF2Cl B24A461 F2CHH Ph CF2Cl B24A462 HCC H Ph CF2Cl B24A463 CH3CC H Ph CF2Cl B24A464 CH2＝CH H Ph CF2Cl B24A465 CH2＝CHCH2H Ph CF2Cl B24A466 CH3SO2N(CH3) H Ph CF2Cl B24A467 (CH3)2N H Ph CF2Cl B24A468 (CH3)2NSO2H Ph CF2Cl B24A469 ClCH2H Ph CF2Cl B24A470 CH3SCH2H Ph CF2Cl B24A471 CH3SOCH2H Ph CF2Cl B24A472 CH3SO2CH2H Ph CF2Cl B24A473 HH Ph CHF2B24A474 CH3H Ph CHF2B24A475 CH3CH2H Ph CHF2B24A476 环丙基 H Ph CHF2B24A477 (CH3)3C H Ph CHF2B24A478 (CH3)2CH H Ph CHF2B24A479 CH3(CH2)2H Ph CHF2B24A480 CH3OCH2H Ph CHF2B24A481 CH3O(CH2)2H Ph CHF2B24A482 Ph H Ph CHF2B24A483 PhO H Ph CHF2B24化合物 R92R93R94R95Q3序号A484 PhS H Ph CHF2B24A485 PhSO H Ph CHF2B24A486 PhSO2H Ph CHF2B24A487 CH3S H Ph CHF2B24A488 CH3SOH Ph CHF2B24A489 CF3H Ph CHF2B24A490 F2CH H Ph CHF2B24A491 HCC H Ph CHF2B24A492 CH3CCH Ph CHF2B24A493 CH2＝CH H Ph CHF2B24A494 CH2＝CHCH2H Ph CHF2B24A495 CH3SO2N(CH3) H Ph CHF2B24A496 (CH3)2NH Ph CHF2B24A497 (CH3)2NSO2H Ph CHF2B24A498 ClCH2H Ph CHF2B24A499 CH3SCH2H Ph CHF2B24A500 CH3SOCH2H Ph CHF2B24A501 CH3SO2CH2H Ph CHF2B24A502 H H Ph CCl3B24A503 CH3H Ph CCl3B24A504 CH3CH2H Ph CCl3B24A505 环丙基H Ph CCl3B24A506 (CH3)3CH Ph CCl3B24A507 (CH3)2CH H Ph CCl3B24A508 CH3(CH2)2H Ph CCl3B24A509 CH3OCH2H Ph CCl3B24A510 CH3O(CH2)2H Ph CCl3B24A511 PhH Ph CCl3B24A512 PhO H Ph CCl3B24A513 PhS H Ph CCl3B24A514 PhSO H Ph CCl3B24A515 PhSO2H Ph CCl3B24化合物 R92R93R94R95Q3序号A516 CH3S H Ph CCl3B24A517 CH3SOH Ph CCl3B24A518 CF3H Ph CCl3B24A519 F2CH H Ph CCl3B24A520 HCC H Ph CCl3B24A521 CH3CCH Ph CCl3B24A522 CH2＝CH H Ph CCl3B24A523 CH2＝CHCH2H Ph CCl3B24A524 CH3SO2N(CH3) H Ph CCl3B24A525 (CH3)2NH Ph CCl3B24A526 (CH3)2NSO2H Ph CCl3B24A527 ClCH2H Ph CCl3B24A528 CH3SCH2H Ph CCl3B24A529 CH3SOCH2H Ph CCl3B24A530 CH3SO2CH2H Ph CCl3B24A531 H CH3H CF3B24A532 H CH3CH2H CF3B24A533 H 环丙基 H CF3B24A534 H (CH3)3CHH CF3B24A535 H (CH3)2CHH CF3B24A536 H CH3(CH2)2H CF3B24A537 H CH3OCH2H CF3B24A538 H CH3O(CH2)2H CF3B24A539 H Ph H CF3B24A540 H PhOH CF3B24A541 H PhSH CF3B24A542 H PhSO H CF3B24A543 H PhSO2H CF3B24A544 H CH3S H CF3B24A545 H CH3SO H CF3B24A546 H CF3H CF3B24A547 H F2CH H CF3B24化合物 R92R93R94R95Q3序号A548 H HCC H CF3B24A549 H CH3CCH CF3B24A550 H CH2＝CH H CF3B24A551 H CH2＝CHCH2H CF3B24A552 H CH3SO2N(CH3) H CF3B24A553 H (CH3)2NH CF3B24A554 H (CH3)2NSO2H CF3B24A555 H CH3SCH2H CF3B24A556 H CH3SOCH2H CF3B24A557 H CH3SO2CH2H CF3B24A558 H CH3H CF3CF2B24A559 H CH3CH2H CF3CF2B24A560 H 环丙基H CF3CF2B24A561 H (CH3)3CH CF3CF2B24A562 H (CH3)2CH H CF3CF2B24A563 H CH3(CH2)2H CF3CF2B24A564 H CH3OCH2H CF3CF2B24A565 H CH3O(CH2)2H CF3CF2B24A566 H PhH CF3CF2B24A567 H PhO H CF3CF2B24A568 H PhS H CF3CF2B24A569 H PhSO H CF3CF2B24A570 H PhSO2H CF3CF2B24A571 H CH3S H CF3CF2B24A572 H CH3SOH CF3CF2B24A573 H CF3H CF3CF2B24A574 H F2CH H CF3CF2B24A575 H HCC H CF3CF2B24A576 H CH3CCH CF3CF2B24A577 H CH2＝CH H CF3CF2B24A578 H CH2＝CHCH2H CF3CF2B24A579 H CH3SO2N(CH3) H CF3CF2B24化合物 R92R93R94R95Q3序号A580 H (CH3)2N H CF3CF2B24A581 H (CH3)2NSO2H CF3CF2B24A582 H CH3SCH2H CF3CF2B24A583 H CH3SOCH2H CF3CF2B24A584 H CH3SO2CH2H CF3CF2B24A585 H CH3H CF3CF2CF2B24A586 H CH3CH2H CF3CF2CF2B24A587 H 环丙基 H CF3CF2CF2B24A588 H (CH3)3C H CF3CF2CF2B24A589 H (CH3)2CHH CF3CF2CF2B24A590 H CH3(CH2)2H CF3CF2CF2B24A591 H CH3OCH2H CF3CF2CF2B24A592 H CH3O(CH2)2H CF3CF2CF2B24A593 H Ph H CF3CF2CF2B24A594 H PhOH CF3CF2CF2B24A595 H PhSH CF3CF2CF2B24A596 H PhSO H CF3CF2CF2B24A597 H PhSO2H CF3CF2CF2B24A598 H CH3S H CF3CF2CF2B24A599 H CH3SO H CF3CF2CF2B24A600 H CF3H CF3CF2CF2B24A601 H F2CH H CF3CF2CF2B24A602 H HCCH CF3CF2CF2B24A603 H CH3CC H CF3CF2CF2B24A604 H CH2＝CH H CF3CF2CF2B24A605 H CH2＝CHCH2H CF3CF2CF2B24A606 H CH3SO2N(CH3) H CF3CF2CF2B24A607 H (CH3)2N H CF3CF2CF2B24A608 H (CH3)2NSO2H CF3CF2CF2B24A609 H CH3SCH2H CF3CF2CF2B24A610 H CH3SOCH2H CF3CF2CF2B24A611 H CH3SO2CH2H CF3CF2CF2B24化合物 R92R93R94R95Q3序号A612 H CH3H CF2Cl B24A613 H CH3CH2H CF2Cl B24A614 H 环丙基 H CF2Cl B24A615 H (CH3)3C H CF2Cl B24A616 H (CH3)2CH H CF2Cl B24A617 H CH3(CH2)2H CF2Cl B24A618 H CH3OCH2H CF2Cl B24A619 H CH3O(CH2)2H CF2Cl B24A620 H Ph H CF2Cl B24A621 H PhO H CF2Cl B24A622 H PhS H CF2Cl B24A623 H PhSOH CF2Cl B24A624 H PhSO2H CF2Cl B24A625 H CH3S H CF2Cl B24A626 H CH3SO H CF2Cl B24A627 H CF3H CF2Cl B24A628 H F2CH H CF2Cl B24A629 H HCC H CF2Cl B24A630 H CH3CC H CF2Cl B24A631 H CH2＝CHH CF2Cl B24A632 H CH2＝CHCH2H CF2Cl B24A633 H CH3SO2N(CH3) H CF2Cl B24A634 H (CH3)2N H CF2Cl B24A635 H (CH3)2NSO2H CF2Cl B24A636 H CH3SCH2H CF2Cl B24A637 H CH3SOCH2H CF2Cl B24A638 H CH3SO2CH2H CF2Cl B24A639 H CH3H CHF2B24A640 H CH3CH2H CHF2B24A641 H 环丙基 H CHF2B24A642 H (CH3)3C H CHF2B24A643 H (CH3)2CH H CHF2B24化合物 R92R93R94R95Q3序号A644 H CH3(CH2)2H CHF2B24A645 H CH3OCH2H CHF2B24A646 H CH3O(CH2)2H CHF2B24A647 H PhH CHF2B24A648 H PhO H CHF2B24A649 H PhS H CHF2B24A650 H PhSO H CHF2B24A651 H PhSO2H CHF2B24A652 H CH3S H CHF2B24A653 H CH3SOH CHF2B24A654 H CF3H CHF2B24A655 H F2CH H CHF2B24A656 H HCC H CHF2B24A657 H CH3CCH CHF2B24A658 H CH2＝CH H CHF2B24A659 H CH2＝CHCH2H CHF2B24A660 H CH3SO2N(CH3) H CHF2B24A661 H (CH3)2N H CHF2B24A662 H (CH3)2NSO2H CHF2B24A663 H CH3SCH2H CHF2B24A664 H CH3SOCH2H CHF2B24A665 H CH3SO2CH2H CHF2B24A666 H CH3H CCl3B24A667 H CH3CH2H CCl3B24A668 H 环丙基H CCl3B24A669 H (CH3)3CH CCl3B24A670 H (CH3)2CH H CCl3B24A671 H CH3(CH2)2H CCl3B24A672 H CH3OCH2H CCl3B24A673 H CH3O(CH2)2H CCl3B24A674 H PhH CCl3B24A675 H PhO H CCl3B24化合物 R92R93R94R95Q3序号A676 H PhS H CCl3B24A677 H PhSO H CCl3B24A678 H PhSO2H CCl3B24A679 H CH3S H CCl3B24A680 H CH3SOH CCl3B24A681 H CF3H CCl3B24A682 H F2CH H CCl3B24A683 H HCC H CCl3B24A684 H CH3CCH CCl3B24A685 H CH2＝CH H CCl3B24A686 H CH2＝CHCH2H CCl3B24A687 H CH3SO2N(CH3) H CCl3B24A688 H (CH3)2N H CCl3B24A689 H (CH3)2NSO2H CCl3B24A690 H CH3SCH2H CCl3B24A691 H CH3SOCH2H CCl3B24A692 H CH3SO2CH2H CCl3B24A693 H CH3CH3CF3B24A694 H CH3CH2CH3CF3B24A695 H 环丙基CH3CF3B24A696 H (CH3)3CCH3CF3B24A697 H (CH3)2CH CH3CF3B24A698 H CH3(CH2)2CH3CF3B24A699 H CH3OCH2CH3CF3B24A700 H CH3O(CH2)2CH3CF3B24A701 H PhCH3CF3B24A702 H PhO CH3CF3B24A703 H PhS CH3CF3B24A704 H PhSO CH3CF3B24A705 H PhSO2CH3CF3B24A706 H CH3S CH3CF3B24A707 H CH3SOCH3CF3B24化合物 R92R93R94R95Q3序号A708 H CF3CH3CF3B24A709 H F2CHCH3CF3B24A710 H HCC CH3CF3B24A711 H CH3CC CH3CF3B24A712 H CH2＝CH CH3CF3B24A713 H CH2＝CHCH2CH3CF3B24A714 H CH3SO2N(CH3) CH3CF3B24A715 H (CH3)2NCH3CF3B24A716 H (CH3)2NSO2CH3CF3B24A717 H CH3SCH2CH3CF3B24A718 H CH3SOCH2CH3CF3B24A719 H CH3SO2CH2CH3CF3B24A720 H CH3CH3CF3CF2B24A721 H CH3CH2CH3CF3CF2B24A722 H 环丙基 CH3CF3CF2B24A723 H (CH3)3C CH3CF3CF2B24A724 H (CH3)2CH CH3CF3CF2B24A725 H CH3(CH2)2CH3CF3CF2B24A726 H CH3OCH2CH3CF3CF2B24A727 H CH3O(CH2)2CH3CF3CF2B24A728 H Ph CH3CF3CF2B24A729 H PhO CH3CF3CF2B24A730 H PhS CH3CF3CF2B24A731 H PhSO CH3CF3CF2B24A732 H PhSO2CH3CF3CF2B24A733 H CH3SCH3CF3CF2B24A734 H CH3SO CH3CF3CF2B24A735 H CF3CH3CF3CF2B24A736 H F2CHCH3CF3CF2B24A737 H HCC CH3CF3CF2B24A738 H CH3CC CH3CF3CF2B24A739 H CH2＝CH CH3CF3CF2B24化合物 R92R93R94R95Q3序号A740 H CH2＝CHCH2CH3CF3CF2B24A741 H CH3SO2N(CH3) CH3CF3CF2B24A742 H (CH3)2N CH3CF3CF2B24A743 H (CH3)2NSO2CH3CF3CF2B24A744 H CH3SCH2CH3CF3CF2B24A745 H CH3SOCH2CH3CF3CF2B24A746 H CH3SO2CH2CH3CF3CF2B24A747 H CH3CH3CF3CF2CF2B24A748 H CH3CH2CH3CF3CF2CF2B24A749 H 环丙基CH3CF3CF2CF2B24A750 H (CH3)3C CH3CF3CF2CF2B24A751 H (CH3)2CHCH3CF3CF2CF2B24A752 H CH3(CH2)2CH3CF3CF2CF2B24A753 H CH3OCH2CH3CF3CF2CF2B24A754 H CH3O(CH2)2CH3CF3CF2CF2B24A755 H PhCH3CF3CF2CF2B24A756 H PhO CH3CF3CF2CF2B24A757 H PhS CH3CF3CF2CF2B24A758 H PhSO CH3CF3CF2CF2B24A759 H PhSO2CH3CF3CF2CF2B24A760 H CH3S CH3CF3CF2CF2B24A761 H CH3SOCH3CF3CF2CF2B24A762 H CF3CH3CF3CF2CF2B24A763 H F2CH CH3CF3CF2CF2B24A764 H HCC CH3CF3CF2CF2B24A765 H CH3CCCH3CF3CF2CF2B24A766 H CH2＝CH CH3CF3CF2CF2B24A767 H CH2＝CHCH2CH3CF3CF2CF2B24A768 H CH3SO2N(CH3) CH3CF3CF2CF2B24A769 H (CH3)2N CH3CF3CF2CF2B24A770 H (CH3)2NSO2CH3CF3CF2CF2B24A771 H CH3SCH2CH3CF3CF2CF2B24化合物 R92R93R94R95Q3序号A772 H CH3SOCH2CH3CF3CF2CF2B24A773 H CH3SO2CH2CH3CF3CF2CF2B24A774 H CH3CH3CF2ClB24A775 H CH3CH2CH3CF2ClB24A776 H 环丙基 CH3CF2ClB24A777 H (CH3)3C CH3CF2ClB24A778 H (CH3)2CH CH3CF2ClB24A779 H CH3(CH2)2CH3CF2ClB24A780 H CH3OCH2CH3CF2ClB24A781 H CH3O(CH2)2CH3CF2ClB24A782 H Ph CH3CF2ClB24A783 H PhO CH3CF2ClB24A784 H PhS CH3CF2ClB24A785 H PhSOCH3CF2ClB24A786 H PhSO2CH3CF2ClB24A787 H CH3S CH3CF2ClB24A788 H CH3SO CH3CF2ClB24A789 H CF3CH3CF2ClB24A790 H F2CH CH3CF2ClB24A791 H HCC CH3CF2ClB24A792 H CH3CC CH3CF2ClB24A793 H CH2＝CHCH3CF2ClB24A794 H CH2＝CHCH2CH3CF2ClB24A795 H CH3SO2N(CH3) CH3CF2ClB24A796 H (CH3)2N CH3CF2ClB24A797 H (CH3)2NSO2CH3CF2ClB24A798 H CH3SCH2CH3CF2ClB24A799 H CH3SOCH2CH3CF2ClB24A800 H CH3SO2CH2CH3CF2ClB24A801 H CH3CH3CHF2B24A802 H CH3CH2CH3CHF2B24A803 H 环丙基 CH3CHF2B24化合物 R92R93R94R95Q3序号A804H(CH3)3C CH3CHF2B24A805H(CH3)2CH CH3CHF2B24A806HCH3(CH2)2CH3CHF2B24A807HCH3OCH2CH3CHF2B24A808HCH3O(CH2)2CH3CHF2B24A809HPh CH3CHF2B24A810HPhO CH3CHF2B24A811HPhS CH3CHF2B24A812HPhSOCH3CHF2B24A813HPhSO2CH3CHF2B24A814HCH3S CH3CHF2B24A815HCH3SO CH3CHF2B24A816HCF3CH3CHF2B24A817HF2CH CH3CHF2B24A818HHCC CH3CHF2B24A819HCH3CC CH3CHF2B24A820HCH2＝CHCH3CHF2B24A821HCH2＝CHCH2CH3CHF2B24A822HCH3SO2N(CH3) CH3CHF2B24A823H(CH3)2N CH3CHF2B24A824H(CH3)2NSO2CH3CHF2B24A825HCH3SCH2CH3CHF2B24A826HCH3SOCH2CH3CHF2B24A827HCH3SO2CH2CH3CHF2B24A828HCH3CH3CCl3B24A829HCH3CH2CH3CCl3B24A830H环丙基 CH3CCl3B24A831H(CH3)3C CH3CCl3B24A832H(CH3)2CH CH3CCl3B24A833HCH3(CH2)2CH3CCl3B24A834HCH3OCH2CH3CCl3B24A835HCH3O(CH2)2CH3CCl3B24化合物 R92R93R94R95Q3序号A836HPh CH3CCl3B24A837HPhO CH3CCl3B24A838HPhS CH3CCl3B24A839HPhSOCH3CCl3B24A840HPhSO2CH3CCl3B24A841HCH3S CH3CCl3B24A842HCH3SO CH3CCl3B24A843HCF3CH3CCl3B24A844HF2CH CH3CCl3B24A845HHCC CH3CCl3B24A846HCH3CC CH3CCl3B24A847HCH2＝CHCH3CCl3B24A848HCH2＝CHCH2CH3CCl3B24A849HCH3SO2N(CH3) CH3CCl3B24A850H(CH3)2N CH3CCl3B24A851H(CH3)2NSO2CH3CCl3B24A852HCH3SCH2CH3CCl3B24A853HCH3SOCH2CH3CCl3B24A854HCH3SO2CH2CH3CCl3B24A855HCH3Ph CF3B24A856HCH3CH2Ph CF3B24A857H(CH3)2CH Ph CF3B24A858H(CH3)2CH Ph CF3B24A859H环丙基 Ph CF3B24A860HCH3(CH2)2Ph CF3B24A861HCH3OCH2Ph CF3B24A862HCH3O(CH2)2Ph CF3B24A863HPh Ph CF3B24A864HPhO Ph CF3B24A865HPhS Ph CF3B24A866HPhSOPh CF3B24A867HPhSO2Ph CF3B24化合物 R92R93R94R95Q3序号A868HCH3S PhCF3B24A869HCH3SO PhCF3B24A870HCF3PhCF3B24A871HF2CH PhCF3B24A872HHCC PhCF3B24A873HCH3CC PhCF3B24A874HCH2＝CHPhCF3B24A875HCH2＝CHCH2PhCF3B24A876HCH3SO2N(CH3) PhCF3B24A877H(CH3)2N PhCF3B24A878H(CH3)2NSO2PhCF3B24A879HCH3SCH2PhCF3B24A880HCH3SOCH2PhCF3B24A881HCH3SO2CH2PhCF3B24A882HCH3PhCF3CF2B24A883HCH3CH2PhCF3CF2B24A884H环丙基 PhCF3CF2B24A885H(CH3)3C PhCF3CF2B24A886H(CH3)2CH PhCF3CF2B24A887HCH3(CH2)2PhCF3CF2B24A888HCH3OCH2PhCF3CF2B24A889HCH3O(CH2)2PhCF3CF2B24A890HPh PhCF3CF2B24A891HPhO PhCF3CF2B24A892HPhS PhCF3CF2B24A893HPhSOPhCF3CF2B24A894HPhSO2PhCF3CF2B24A895HCH3S PhCF3CF2B24A896HCH3SO PhCF3CF2B24A897HCF3PhCF3CF2B24A898HF2CH PhCF3CF2B24A899HHCC PhCF3CF2B24化合物 R92R93R94R95Q3序号A900HCH3CC PhCF3CF2B24A901HCH2＝CH PhCF3CF2B24A902HCH2＝CHCH2Ph CF3CF2B24A903HCH3SO2N(CH3) Ph CF3CF2B24A904H(CH3)2NPh CF3CF2B24A905H(CH3)2NSO2Ph CF3CF2B24A906HCH3SCH2Ph CF3CF2B24A907HCH3SOCH2Ph CF3CF2B24A908HCH3SO2CH2PhCF3CF2B24A909HCH3PhCF3CF2CF2B24A910HCH3CH2PhCF3CF2CF2B24A911H环丙基 PhCF3CF2CF2B24A912H(CH3)3C PhCF3CF2CF2B24A913H(CH3)2CH PhCF3CF2CF2B24A914HCH3(CH2)2PhCF3CF2CF2B24A915HCH3OCH2PhCF3CF2CF2B24A916HCH3O(CH2)2PhCF3CF2CF2B24A917HPh PhCF3CF2CF2B24A918HPhO PhCF3CF2CF2B24A919HPhS PhCF3CF2CF2B24A920HPhSO PhCF3CF2CF2B24A921HPhSO2PhCF3CF2CF2B24A922HCH3SPhCF3CF2CF2B24A923HCH3SO PhCF3CF2CF2B24A924HCF3PhCF3CF2CF2B24A925HF2CHPhCF3CF2CF2B24A926HHCC PhCF3CF2CF2B24A927HCH3CC PhCF3CF2CF2B24A928HCH2＝CH PhCF3CF2CF2B24A929HCH2＝CHCH2PhCF3CF2CF2B24A930HCH3SO2N(CH3) PhCF3CF2CF2B24A931H(CH3)2NPhCF3CF2CF2B24化合物 R92R93R94R95Q3序号A932H(CH3)2NSO2PhCF3CF2CF2B24A933HCH3SCH2PhCF3CF2CF2B24A934HCH3SOCH2PhCF3CF2CF2B24A935HCH3SO2CH2PhCF3CF2CF2B24A936HCH3PhCF2ClB24A937HCH3CH2PhCF2ClB24A938H环丙基 PhCF2ClB24A939H(CH3)3C PhCF2ClB24A940H(CH3)2CH PhCF2ClB24A941HCH3(CH2)2PhCF2ClB24A942HCH3OCH2PhCF2ClB24A943HCH3O(CH2)2PhCF2ClB24A944HPh PhCF2ClB24A945HPhO PhCF2ClB24A946HPhS PhCF2ClB24A947HPhSOPhCF2ClB24A948HPhSO2PhCF2ClB24A949HCH3S PhCF2ClB24A950HCH3SO PhCF2ClB24A951HCF3PhCF2ClB24A952HF2CH PhCF2ClB24A953HHCC PhCF2ClB24A954HCH3CC PhCF2ClB24A955HCH2＝CHPhCF2ClB24A956HCH2＝CHCH2PhCF2ClB24A957HCH3SO2N(CH3) PhCF2ClB24A958H(CH3)2N PhCF2ClB24A959H(CH3)2NSO2PhCF2ClB24A960HCH3SCH2PhCF2ClB24A961HCH3SOCH2PhCF2ClB24A962HCH3SO2CH2PhCF2ClB24A963HCH3PhCHF2B24化合物 R92R93R94R95Q3序号A964HCH3CH2PhCHF2B24A965H(CH3)3C PhCHF2B24A966H(CH3)2CH PhCHF2B24A967H环丙基 PhCHF2B24A968HCH3(CH2)2PhCHF2B24A969HCH3OCH2PhCHF2B24A970HCH3O(CH2)2PhCHF2B24A971HPh PhCHF2B24A972HPhO PhCHF2B24A973HPhS PhCHF2B24A974HPhSOPhCHF2B24A975HPhSO2PhCHF2B24A976HCH3S PhCHF2B24A977HCH3SO PhCHF2B24A978HCF3PhCHF2B24A979HF2CH PhCHF2B24A980HHCC PhCHF2B24A981HCH3CC PhCHF2B24A982HCH2＝CHPhCHF2B24A983HCH2＝CHCH2PhCHF2B24A984HCH3SO2N(CH3) PhCHF2B24A985H(CH3)2N PhCHF2B24A986H(CH3)2NSO2PhCHF2B24A987HCH3SCH2PhCHF2B24A988HCH3SOCH2PhCHF2B24A989HCH3SO2CH2PhCHF2B24A990HCH3PhCCl3B24A991HCH3CH2PhCCl3B24A992H(CH3)3C PhCCl3B24A993H(CH3)2CH PhCCl3B24A994H环丙基 PhCCl3B24A995HCH3(CH2)2PhCCl3B24化合物 R92R93R94R95Q3序号A996 H CH3OCH2Ph CCl3B24A997 H CH3O(CH2)2Ph CCl3B24A998 H Ph Ph CCl3B24A999 H PhO Ph CCl3B24A1000H PhS Ph CCl3B24A1001H PhSOPh CCl3B24A1002H PhSO2Ph CCl3B24A1003H CH3S Ph CCl3B24A1004H CH3SO Ph CCl3B24A1005H CF3Ph CCl3B24A1006H F2CH Ph CCl3B24A1007H HCC Ph CCl3B24A1008H CH3CC Ph CCl3B24A1009H CH2＝CHPh CCl3B24A1010H CH2＝CHCH2Ph CCl3B24A1011H CH3SO2N(CH3) Ph CCl3B24A1012H (CH3)2N Ph CCl3B24A1013H (CH3)2NSO2Ph CCl3B24A1014H CH3SCH2Ph CCl3B24A1015H CH3SOCH2Ph CCl3B24A1016H CH3SO2CH2Ph CCl3B24A1017F HHCF3B24A1018Cl HHCF3B24A1019Br HHCF3B24A1020CN HHCF3B24A1021CH3SO2O HHCF3B24A1022CH3O HHCF3B24A1023CH2CH3O HHCF3B24A1024CH2CH＝CH2O HHCF3B24A1025HCCCH2O HHCF3B24A1026S-苄基HHCF3B24A1027SO2-苄基 HHCF3B24化合物 R92R93R94R95Q3序号A1028 ClCH2H H CF3B24A1029 BrCH2H H CF3B24A1030 FCH2H H CF3B24A1031 CHF2CH2H H CF3B24A1032 CF3CH2H H CF3B24A1033 三唑基甲基H H CF3B24A1034 CHCl2CH2H H CF3B24A1035 ClCH＝CH H H CF3B24A1036 Cl2C＝CH H H CF3B24A1037 CF3CH＝CHH H CF3B24A1038 ClCC H H CF3B24A1039 PhH H CF3B24A1040 CH3CH3H CF3B24A1041 CH3OHH CF3B24A1042 CH3F H CF3B24A1043 CH3ClH CF3B24A1044 F CH3H CF3B24A1045 ClCH3H CF3B24A1046 H F H CF3B24A1047 H ClH CF3B24A1048 H BrH CF3B24A1049 H OHH CF3B24A1050 H OCH3H CF3B24A1051 H OCHF2H CF3B24A1052 H OSO2CH3H CF3B24A1053 H OSO2CF3H CF3B24A1054 H ClCH2H CF3B24A1055 H BrCH2H CF3B24A1056 H FCH2H CF3B24A1057 H CHF2CH2H CF3B24A1058 H CF3CH2H CF3B24A1059 H 三唑基甲基 H CF3B24化合物 R92R93R94R95Q3序号A1060 HCHCl2CH2H CF3B24A1061 HClCH＝CH H CF3B24A1062 HCl2C＝CH H CF3B24A1063 HCF3CH＝CH H CF3B24A1064 HClCC H CF3B24A1065 HCH3C(O) H CF3B24A1066 H苯基 H CF3B24A1067 HSO2CH3H CF3B24A1068 HSO2CF3H CF3B24A1069 HCN H CF3B24A1070 HNO2H CF3B24A1071 CH3H F CF3B24A1072 CH3H Cl CF3B24A1073 CH3H Br CF3B24A1074 CH3H CN CF3B24A1075 CH3H CH3O CF3B24A1076 CH3H CH3S CF3B24A1077 CH3H CH3SO CF3B24A1078 CH3H CH3SO2CF3B24表9a式Ig化合物 Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B1 B2 B3 B4 B5 B6 B7 B8 B9 B10B11B12B13B14B15B16B17B18B19B20B21B22B23B24B25B26B27B28B29B30B31B32B33B34B35B36B37B38B39B40B41B42B43B44B45B46B47B48Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 E516B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083表10式Ih化合物 Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B1B2B3B4B5B6B7B8B9B10 B11 B12B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083表11式Ik化合物 Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B1B2B3B4B5B6B7B8B9B10 B11 B12B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083表12式Im化合物 Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B1B2B3B4B5B6B7B8B9B10 B11 B12B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083表13式In化合物 Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B1 B2 B3B4 B5 B6 B7B8 B9 B10 B11 B12B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083表14式Io化合物 Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B1B2B3B4B5B6B7B8B9B10 B11 B12B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083表15式Ip化合物 Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B1B2B3B4B5B6B7B8B9B10 B11 B12B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083表16式Iq化合物 Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B1B2B3B4B5B6B7B8B9B10 B11 B12B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3Q3B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083表17式Ir化合物 Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6Q6C1C2C3C4C5C6C7C8C9C10 C11 C12C13 C14 C15 C16 C17 C18 C19 C20 C21 C22 C23 C24C25 C26 C27 C28 C29 C30 C31 C32 C33 C34 C35 C36C37 C38 C39 C40 C41 C42 C43 C44 C45 C46 C47 C48C49 C50 C51 C52 C53 C54 C55 C56 C57 C58 C59 C60C61 C62 C63 C64 C65 C66 C67 C68 C69 C70 C71 C72C73 C74 C75 C76 C77 C78 C79 C80 C81 C82 C83 C84C85 C86 C87 C88 C89 C90 C91 C92 C93 C94 C95 C96C97 C98 C99 C100 C101 C102 C103 C104 C105 C106 C107 C108C109 C110 C111 C112 C113 C114 C115 C116 C117 C118 C119 C120C121 C122 C123 C124 C125 C126 C127 C128 C129 C130 C131 C132C133 C134 C135 C136 C137 C138 C139 C140 C141 C142 C143 C144C145 C146 C147 C148 C149 C150 C151表18式Is化合物 Q7Q7Q7Q7Q7Q7Q7Q7Q7Q7Q7Q7D1D2D3D4D5D6D7D8D9D10 D11 D12D13 D14 D15 D16 D17 D18 D19 D20 D21 D22 D23 D24D25 D26 D27 D28 D29 D30 D31 D32 D33 D34 D35 D36D37 D38 D39 D40 D41 D42 D43 D44 D45 D46 D47 D48D49 D50 D51 D52 D53 D54 D55 D56 D57 D58 D59 D60D61 D62 D63 D64 D65 D66 D67 D68 D69 D70 D71 D72D73 D74 D75 D76 D77 D78 D79 D80 D81 D82 D83 D84D85 D86 D87 D88 D89 D90 D91 D92 D93 D94 D95 D96D97 D98 D99 D100 D101 D102 D103 D104 D105 D106 D107 D108D109 D110 D111 D112 D113 D114 D115 D116 D117 D118 D119 D120Q7Q7Q7Q7Q7Q7Q7Q7Q7Q7Q7Q7D121 D122 D123 D124 D125 D126 D127 D128 D129 D130 D131 D132D133 D134 D135 D136 D137 D138 D139 D140表19式Iv化合物 化合物序号R75E1CH2OCH3E2CH2OC2H5E3CH2O-正丙基E4CH2O-异丙基E5CH2O-正丁基E6CH2O-异丁基E7CH2O-叔丁基E8(CH2)2OCH3E9(CH2)2O-乙基E10 (CH2)2O-正丙基E11 (CH2)2O-异丙基E12 (CH2)2O-正丁基E13 (CH2)2O-异丁基E14 (CH2)2O-叔丁基E15 (CH2)2O(CH2)2OCH3E16 (CH2)2O(CH2)2OCH3E17 C2H5表20表5-19的物理数据(数据＝m.p.，单位为℃)化合物 物理数据 化合物 物理数据 化合物 物理数据A2 150-151 C46 159-161A2-B105888-89A3 148-149 C91 141-143A2-B1066粘稠物A4 143-144 C14699-101 A2-B1067树脂油状物A5 81-82C149148-150A2-B1069油状物A6 148-150 A2-B1 90-92 A2-B1069粘稠油状物A7 105-106 A2-B68 120-121A8-B1 97-98A8 123-124 A2-B2 树脂状物 A7-B1 油状物A9 73-74A2-B90 树脂状物 A3-B1 42-44A10165-167 A2-B93 95-96 A94-B1 57-58A15164-166 A2-B46 61-62顺式-rac A66-B24 80-82A1799-100 A2-B46 83-84反式-rac A64-B1 49-51A26143-144 A2-B91 树脂状物 A154-B1 94-95A27107-108 A2-B1081油状物 A6-B1 123-124A29173-174 A2-B1082树脂状物 A6-B24 油状物A30178-181 A2-B1083树脂状物 A34-B1 53-54A31209-210 A2-B29 87-88 A2-B25 油状物A32145-146 A2-B73 树脂状物 A2-B925 油状物A34170-171 A2-B95 106-107E8 55-56A64134-135 A2-B31 151-153E17 99-101A94134-135 A2-B75 无定形物A154 108-110 A2-B24 油状物B1057 166-167 A2-B5 树脂状物B1058 结晶 A2-C91 树脂状物B1061 结晶 A2-C146 油状物B1063 结晶 A2-B112 树脂状物B1065 油状物 A2-D140 油状物B1066 150-152 A2-B1057无定形物B1067 122-123 A2-B1063油状物B1069 117-118 A2-B1061油状物B1070 结晶 A2-B133 油状物式2.1和2.3-2.13.c化合物的名称是甲氧咪草烟、咪唑乙烟酸、咪唑喹啉酸、咪唑烟酸、二甲吩草胺、莠去津、特丁津、西玛津、特丁净、氰乙酰肼、莠灭净、甲氧去草净、调环酸钙、稀禾定、烯草酮、吡喃草酮(tepraloxydim)、唑嘧磺草胺、磺草唑胺、哒草特、溴苯腈、碘苯腈、磺草酮、唑酮草酯(carfentrazone)、甲磺草胺、异噁唑草酮、草铵膦、氟嘧磺隆、氟磺隆、砜嘧磺隆、氯吡嘧磺隆、烟嘧磺隆、乙氧嘧磺隆、啶嘧磺隆和噻吩磺隆，并且以下列条目号描述在《农药手册》(PesticideManual)，第11版，英国作物保护委员会(British Crop ProtectionCouncil)，1997中412、415、414、413、240、34、692、651、693、168、20、691、595、648、146、49、339、495、626、88、425、664、112、665、436、382、589、613、644、389、519、287、325和704。其中Y1、Y3和Y4是次甲基，Y2是C-I，R74是COOMe，Y5是氮，Y6是甲基，且Y7是甲氧基的式2.13化合物以名称碘甲磺隆(尤其是钠盐)描述在AGROWNo.296，16th 1月1998，p.22中。其中Y1、Y2、Y3和Y4是次甲基，R74是三氟甲基，Y5是氮，Y6是三氟甲基，且Y7是甲氧基的式2.13化合物的名称是甲酰氨磺隆，并描述在DE-A-40 38 430中。其中Y1是NH-CHO，Y2、Y3和Y4是次甲基，R74是CONMe2，Y5是次甲基，且Y6和Y7是甲氧基的式2.13化合物描述在例如WO 95/29899中。
式2.12化合物的S对映体以CAS-Reg.No.[35597-44-5]登记。通式2.2化合物，aRS，1’S(-)N-(1’-甲基-2’-甲氧基-乙基)-N-氯乙酰基-2-乙基-6-甲基苯胺，和通式2.3化合物，(1S，aRS)-2-氯-N-(2，4-二甲基-3-噻吩基)-N-(2-甲氧基-1-甲基乙基)-乙酰胺描述在例如WO97/34485中。其中R69是NO2的式2.9化合物的名称是甲基磺草酮，并且描述在例如US-A-5 006 158中。其中R62是乙氧基，R63是氟，Y是次甲基，R64是甲氧基羰基，R65是氢，且R66是氯的式2.6化合物的名称是氯酯磺草胺(cloransulam)，并描述在例如AGROW No.261，2nd 8月1996，p.21中。其中R62是甲氧基，R63是氢，Y是C-F，R64是氟，R65是氢，且R66是氟的式2.6化合物的名称是双氟磺草胺，并描述在US-A-5 163 995中。
此外，本发明组合物的下列化合物描述在《农药手册》(PesticideManual)，第11版，英国作物保护委员会(British Crop ProtectionCouncil)，1997中式化合物(名称) 《农药手册》第11版，条目号2.14(嗪草酮) 4972.15(苯草醚) 82.16(草甘膦) 3832.17(灭草松) 652.18(二甲戊灵)5572.19(麦草畏) 2102.20(丁草敌) 1002.22(异恶草松)1502.23(2，4-D) 1922.24(氟烯草酸)3402.25(氟噻甲草酯) 3592.26(呋草酮) 3562.27(丙炔氟草胺) 3412.28(百草枯) 5502.29(唑啶草酮)372.30(fluthiamid) 512.33(sulfosate) 3832.34(磺草灵) 332.35(氟草敏) 5262.36(特草定) 6892.37(噻唑烟酸)7022.38(氟硫草定)2592.39(环嗪酮) 4002.40(敌草隆) 2602.41(MCPA)4552.42(甲氯丙酸)4592.43(丁噻隆) 683其中R67是氢的式2.7化合物及其制备描述在US-A-3 790 571中；其中R62是乙氧基，Z是氮，R63是氟，R64是氯，R65是氢，且R66是氯的式2.6化合物描述在US-A-5 498 773中。式2.21化合物及其制备描述在US-A-5 183 492中；式2.22化合物以名称双环磺草酮描述在AGROW No.296，16th 1月1998，p.22中。式2.31化合物以名称四唑酰草胺描述在1997年英国作物保护会议-杂草，会议论文集(The 1997 British CropProtect ion Conference-Weeds，Conference Proceedings)Vol.1，2-8，p.67-72中；式2.32化合物以名称JV 485(isoxapropazol)描述在1997年英国作物保护会议-杂草，会议论文集Vol.1，3A-2，p.93-98中。式2.44化合物的名称是pethoxamid，并描述在EP-A-0 206 251中。式2.45化合物的名称是丙苯磺隆，并描述在EP-A-0 507 171中；式2.46化合物的名称是异丙吡草酯，并描述在例如US-A-5 530 126中。式2.47化合物的名称是吲哚酮草酯，并描述在例如DE-A-4 037 840中。式2.48化合物的名称是双苯嘧草酮，并描述在例如WO 97/08953中。式2.49化合物的名称是氟吡草腙，并描述在例如EP-A-0 646 315中。式2.50化合物(氨唑草酮)及其制备公开在DD 298 393和US-A-5 194 085中。式2.51化合物(flufenpyr-ethyl)描述在美国化学会论文文摘(Abstractsof Papers American Chemical Society)，(2000)Vol.220，No.部分1，pp.AGRO 174中。
非常令人惊奇的是，式I活性组分与一种或多种选自式2.1-2.51的活性组分的组合对欲控制杂草的作用超过了一般所预计的加和作用，因此扩大了单独活性组分的作用范围，尤其是在下列两个方面首先，减小了单独的式2.1-2.51化合物的施用量，同时保持了良好的作用水平，其次，对于单独的活性物质以低施用量不可用的情况(从农学角度来看)，本发明组合物亦可获得良好的杂草控制水平。该结果是杂草谱的显著拓宽，并且提高了在有用植物农作物方面的选择性，如果发生了活性组分的非故意剂量过多，这样的结果是必须的并且希望的。在保持良好控制有用植物农作物中的杂草的同时，本发明组合物还使得在继代农作物中有更大的灵活性。
本发明组合物可用于抗大量在农业上很重要的杂草，例如繁缕属、豆瓣菜属、剪股颖属、马唐属、燕麦属、狗尾草属、芥属、毒麦属、茄属、菜豆属、稗属、藨草属、雨久花属、慈菇属、雀麦属、看麦娘属、石茅高梁、筒轴茅属、莎草属、苘麻属植物、黄花稔属、苍耳属、苋属、藜属、番薯属、苘蒿属、猪殃殃属、堇菜属和婆婆纳属。本发明组合物适用于农业中的所有常用施用方法，例如芽前施用、苗后施用和种子包衣。本发明组合物尤其适用于控制有用植物农作物例如禾谷类植物、油菜、甜菜、甘蔗、种植园农作物、稻、玉米和大豆中的杂草，以及适用于非选择性杂草控制。
“农作物”还指通过常规育种或基因工程方法使其对除草剂或除草剂类别耐受的农作物。
本发明组合物包含任意混合比例的式I活性组分和式2.1-2.51活性组分，但是其中一种组分的量通常超过另一种组分的量。式I活性组分与式2.1-2.51混合配伍的混合比例(重量比)一般为1∶2000-2000∶1、尤其是200∶1-1∶200。
施用量可在宽的限度内变化，并取决于土壤性质、施用方法(芽前或苗后；种子包衣；播沟施用；非耕种施用等)、农作物植物、欲控制的杂草、主要的气候条件、和由施用方法控制的其它因素、施用时间和目标农作物。本发明活性组分混合物一般可以以1-5000g活性组分混合物/公顷的比例施用。
式I化合物与式式2.1-2.51化合物的混合物可以以未改性的形式使用，也就是说，以合成所获得的形式使用。然而，优选以常规方式将它们与制剂技术常用的助剂例如溶剂、固体载体或表面活性剂一起加工配制，例如配制成乳油、可直接喷雾或稀释的溶液、稀的乳剂、可湿性粉剂、可溶性粉剂、粉尘剂、粒剂或微胶囊。根据使用目的和主要环境来选择作为组合物性质的施用方法例如喷雾、雾化、撒布、润湿、撒施或浇泼。
制剂，即包含式I和式2.1-2.51化合物(活性组分)、以及适当时一种或多种固体或液体制剂助剂的组合物、制剂或混合物是以自身已知的方式制得的，例如通过将活性组分与制剂助剂例如溶剂或固体载体充分混合和/或研磨而制得。此外，在制剂的制备中可使用表面活性化合物(表面活性剂)。
溶剂和固体载体的实例描述在例如WO 97/34485第6页中。
根据欲配制的式I化合物的性质，合适的表面活性化合物是具有良好乳化、分散和润湿性质的非离子、阳离子和/或阴离子表面活性剂以及表面活性剂混合物。
合适的阴离子、非离子和阳离子表面活性剂描述在例如WO 97/34485第7和8页中。
制剂技术常用的表面活性剂也适用于本发明除草组合物的制备，这些表面活性剂特别描述在《McCutcheon洗涤剂和乳化剂年鉴》(″McCutcheon’s Detergents and Emulsifiers Annual″)MC PublishingCorp.，Ridgewood New Jersey，1981，Stache，H.，″Tensid-Taschenbuch″，Carl Hanser Verlag，Munich/Nienna，1981以及M.和J.Ash，《表面活性剂大全》(″Encyclopedia of Surfactants″)，Vol 1-111，Chemical Publishing Co.，New York，1980-81中。
除草制剂通常含有0.1-99％重量、尤其是0.1-95％重量的包含式I化合物和式2.1-2.51化合物的活性组分混合物，1-99.9％重量的固体或液体制剂助剂，和0-25％重量、尤其是0.1-25％重量的表面活性剂。
然而，市售产品一般是配制成浓缩物，最终的使用者通常使用稀释的制剂。组合物还可以含有其它组分，例如稳定剂如植物油或环氧化植物油(环氧化椰子油、菜籽油或豆油)，消泡剂例如硅油，防腐剂，粘度调节剂，粘合剂，增粘剂，以及肥料和其它活性组分。优选的制剂具有尤其是下列组成(％＝重量百分比)乳油活性组分混合物1-90％、优选5-20％表面活性剂1-30％、优选10-20％液体载体 5-94％、优选70-85％粉剂活性组分混合物0.1-10％、优选0.1-5％固体载体 99.9-90％、优选99.9-99％胶悬剂活性组分混合物5-75％、优选10-50％水94-24％、优选88-30％表面活性剂1-40％、优选2-30％可湿性粉剂活性组分混合物0.5-90％、优选1-80％表面活性剂0.5-20％、优选1-15％固体载体 5-95％、优选15-90％粒剂活性组分混合物0.1-30％、优选0.1-15％固体载体 99.5-70％、优选97-85％下列实施例进一步举例说明了本发明，但不是限制本发明。F1.乳油a) b) c) d)活性组分混合物 5％ 10％25％50％十二烷基苯磺酸钙6％ 8％ 6％ 8％蓖麻油聚乙二醇醚4％ - 4％ 4％(36mol氧化乙烯)辛基苯酚聚乙二醇醚 - 4％ - 2％(7-8mol氧化乙烯)环己酮 - - 10％20％芳烃混合物 85％78％55％16％C9-C12
通过用水稀释，可由这样的乳油获得任意所需浓度的乳剂。F2.溶液a) b)c)d)活性组分混合物5％ 10％ 50％ 90％1-甲氧基-3-(3-甲氧基丙氧基)-丙烷 -20％ 20％ -聚乙二醇MW 40020％ 10％ - -N-甲基-2-吡咯烷酮 -- 30％ 10％芳烃混合物75％ 60％ - -C9-C12该溶液适于以微滴的形式使用。F3.可湿性粉剂a) b) c) d)活性组分混合物 5％25％50％80％木质素磺酸钠 4％- 3％ -十二烷基硫酸钠 2％3％ - 4％二异丁基萘磺酸钠 - 6％ 5％ 6％辛基苯酚聚乙二醇醚 - 1％ 2％ -(7-8mol氧化乙烯)高度分散的硅酸 1％3％ 5％ 10％高岭土 88％ 62％35％-将活性组分与助剂充分混合，并将该混合物在合适的研磨机中磨碎，获得了可湿性粉剂，可以用水稀释以获得任意所需浓度的悬浮剂。F4.包衣粒剂a)b) c)活性组分混合物 0.1％ 5％ 15％高度分散的硅酸 0.9％ 2％ 2％无机载体99.0％93％83％(φ0.1-1mm)例如CaCO3或SiO2
将活性组分溶解在二氯甲烷中，通过喷雾施加到载体上，然后将溶剂真空蒸发。F5.包衣粒剂a) b)c)活性组分混合物 0.1％5％ 15％聚乙二醇MW 200 1.0％2％ 3％高度分散的硅酸 0.9％1％ 2％无机载体98.0％ 92％ 80％(φ0.1-1mm)例如CaCO3或SiO2在混合器中将细研磨的活性组分均匀地施加到用聚乙二醇润湿的载体上。以该方式获得了无粉尘的包衣粒剂。F6.挤出粒剂a)b) c) d)活性组分混合物 0.1％ 3％ 5％ 15％木质素磺酸钠1.5％ 2％ 3％ 4％羧甲基纤维素1.4％ 2％ 2％ 2％高岭土 97.0％93％90％79％将活性组分混合，与助剂研磨，用水将该混合物润湿。将该混合物挤出，然后在气流中干燥。F7.粉剂a)b) c)活性组分混合物 0.1％ 1％ 5％滑石粉 39.9％49％35％高岭土 60.0％50％60％即用型粉尘剂是通过将活性组分与载体混合、并将混合物在合适的研磨机中研磨而获得的。F8.胶悬剂a) b) c) d)活性组分混合物 3％ 10％ 25％50％乙二醇 5％ 5％ 5％ 5％壬基苯酚聚乙二醇醚 -1％ 2％ -(15mol氧化乙烯)木质素磺酸钠3％ 3％ 4％ 5％羧甲基纤维素1％ 1％ 1％ 1％37％甲醛水溶液 0.2％0.2％0.2％ 0.2％硅油乳液0.8％0.8％0.8％ 0.8％水 87％ 79％ 62％38％将细研磨的活性组分与助剂充分混合，获得了胶悬剂，通过用水稀释可由其获得任意所需浓度的悬浮液。
实际上更经常将式I化合物与式2.1-2.51混合伴侣单独配制，临用前在施用器中将其以所需混合比例以“桶混”的形式混合在一起。生物实施例当式I与2.1-2.51化合物的活性组分组合的作用大于单独施用的活性组分的作用之和时，即存在协同作用。
对于给定的两种除草剂组合，预计的除草作用We可如下计算(参见COLBY，S.R.，″计算除草剂组合的协同和拮抗反应″，《杂草》(Weeds)15，p.20-22，1967)We＝X+[Y·(100-X)/100]其中X＝与未处理的对照(＝0％)相比，在用式I化合物以pkg/公顷的施用量处理时的除草作用百分比。Y＝与未处理的对照相比，在用式2.1-2.51化合物以qkg/公顷的施用量处理时的除草作用百分比。We＝在用式I和2.1-2.51化合物以p+qkg/公顷的施用量处理后，预计的除草作用(与未处理的对照相比，除草作用百分比)。
当实际上观测到的作用大于预计的We的值时，即存在协同作用。
在下列实施例中证实了式I化合物与式2.1-2.51化合物的组合的协同作用。实验描述-芽前测试将塑料盆内的标准土壤中播种单子叶和双子叶测试植物。播种后，立即通过喷雾施用水悬浮液形式的测试物(500升水/ha)。施用量取决于在大田条件和温室条件下确定的最适剂量。然后让测试植物在温室中于最适条件下生长。36天后评价测试(％作用，100％＝植物已经死亡，0％＝没有植物毒害作用)。本发明组合物的协同作用的实例如下表B1-B6所示混合物A含有915g/升式2.2a化合物和45g/升式3.1化合物作为活性组分。表B1
表B2
表B3
表B4
表B5
表B6
实验描述-苗后测试
将测试植物在塑料盆中于温室条件下生长至2-叶-3-叶期。使用标准土壤作为栽培基质。在2-叶-3-叶期，将除草剂以自身的形式并作为混合物施加到测试植物上。施加是用测试物在500升水/ha中的水悬浮液进行的。施用量取决于在大田条件和温室条件下确定的最适剂量。33天后评价测试(％作用，100％＝植物已经死亡，0％＝没有植物毒害作用)。本发明组合物的协同作用的实例如下表B7-B10所示混合物A含有915g/升式2.2a化合物和45g/升式3.1化合物作为活性组分。表B7苗后测试
表B8苗后测试
表B9苗后测试
表B10苗后测试
在下表中，是在14天后进行评价表B11芽前作用
表B12芽前作用
表B13芽前作用
表B14芽前作用化合物2.13a相当于这样的式2.13化合物，其中R74是-CH2CH2CF3，Y1、Y2、Y3和Y4各是次甲基，Y5是氮，且Y6是甲基。
表B15芽前作用
表B16芽前作用
表B17芽前作用化合物2.4.a相当于其中R57是氯、R58是乙基、且R59是叔丁基的式2.4化合物。
表B18芽前作用
表B19芽前作用化合物2.3.a相当于其中R56是CH(Me)-CH2OMe的式2.3化合物。
表B20芽前作用化合物2.2.c相当于其中R53和R54是乙基，且R55是CH2OMe的式2.2化合物。
表B21芽前作用化合物2.2.d相当于其中R53是乙基、R54是甲基、且R55是CH2O-CH2CH3的式2.2化合物。
表B22芽前作用
在下表中，是在31天后进行评价表B23芽前作用化合物2.4.a相当于其中R57是氯、R58是乙基、且R59是异丙基的式2.4化合物。
表B24芽前作用化合物2.4.b相当于其中R57是氯、R58是乙基、且R59是乙基的式2.4化合物。
表B25芽前作用化合物2.4.c相当于其中R57是氯、R58是乙基、且R59是叔丁基的式2.4化合物。
表B26芽前作用化合物2.4.d相当于其中R57是甲硫基、R58是乙基、且R59是叔丁基的式2.4化合物。
表B27芽前作用
表B28芽前作用化合物2.6.a相当于这样的式2.6化合物，其中R62是氢、R63是甲基、R64是氟、R65是氢、Y是氮、Z是次甲基、且R66是氟。
在下表中，是在21天后进行评价。表B29苗后作用化合物2.7.a相当于其中R67是-C(O)-S-正辛基的式2.7化合物。
表B30苗后作用
表B31苗后作用
表B32苗后作用
表B33苗后作用化合物2.12.a相当于其中R73是NH2的式2.12化合物。
表B34苗后作用
表B35苗后作用化合物2.1.a相当于其中R52是氢、且R51是乙基的式2.1化合物。
表B36苗后作用化合物2.1.b相当于其中R51是CH2OMe、且R52是氢的式2.1化合物。
在下表中，是在23天后进行评价表B37芽前作用化合物2.13.b相当于这样的式2.13化合物，其中R74是-COOMe，Y1、Y2、Y3和Y4各是次甲基，Y5是次甲基，且Y6和Y7是二氟甲氧基。
表B38芽前作用
表B39芽前作用化合物2.13.d相当于这样的式2.13化合物，其中Y1、Y2、Y3和Y4是次甲基，R74是三氟甲基，Y5是氮，Y6是三氟甲基，且Y7是甲氧基。
已经令人惊奇地表明，特定的安全剂适于和本发明协同组合物混合。因此，本发明还涉及用于控制有用植物农作物、尤其是玉米农作物中的禾草和杂草的选择性除草组合物，所述组合物包含式I化合物、一种或多种选自式2.1-2.51化合物的化合物、和安全剂(对抗剂、解毒剂)，所述组合物保护有用植物、但是不保护杂草，并对抗除草剂的植物毒害作用，以及这样的组合物在控制有用植物中的杂草中的应用。
本发明还提供了选择性除草组合物，所述组合物除了包含常用惰性制剂助剂例如载体、溶剂和润湿剂以外，还包含下列组分的混合物作为活性组分a)除草协同有效量的式I化合物和一种或多种选自式2.1-2.51化合物的化合物，和b)除草拮抗有效量的选自下列的化合物式3.1化合物
和式3.2化合物 和式3.3化合物 和式3.4化合物 和式3.5化合物 和式3.6化合物 和式3.7化合物 和式3.8化合物 和式3.9化合物Cl2CHCON(CH2CH＝CH2)2(3.9)，和式3.10化合物 和式3.11化合物 和式3.12化合物 及其乙酯和式3.13化合物 和式3.14化合物 和式3.15化合物 和式3.16化合物 本发明还提供了选择性除草组合物，所述组合物除了包含常用惰性制剂助剂例如载体、溶剂和润湿剂以外，还包含下列组分的混合物作为活性组分a)除草有效量的式I化合物，和b)除草拮抗有效量的选自式3.1、3.2、3.3、3.4、3.5、3.6、3.7、3.8、3.9、3.10、3.11、3.12、3.13、3.14、3.15和3.16化合物的化合物。
优选的本发明组合物包含选自式3.1、3.3和3.8化合物的化合物作为安全剂。这样安全剂尤其适用于包含上述优选的式I化合物和任选的式2.1-2.51化合物的本发明组合物。
已经表明，式I化合物与式3.1化合物的组合是特别有效的组合物，化合物1.001是特别优选的式I化合物。该组合物优选与式2.2a化合物一起使用 (2.2a，aRS，1’S(-)N-(1’-甲基-2’-甲氧基乙基)-N-氯乙酰基-2-乙基-6-甲基苯胺)。
本发明还涉及选择性地控制有用植物农作物中的杂草的方法，所述方法包括用除草有效量的式I除草剂、视情况而定的一种或多种选自式2.1-2.51化合物的除草剂、和除草拮抗有效量的式3.1-3.16安全剂来处理有用植物、种子或其切条、或其耕作区域。
式3.1-3.16化合物是已知的，并描述在例如《农药手册》，第11版，英国作物保护委员会，1997中，条目号为61(式3.1，解草嗪)、304(式3.2，解草啶)、154(式3.3，解草酯)、462(式3.4，吡咯解草酯)、377(式3.5，解草恶唑)、363(式3.8，氟草肟)、213(式3.9，烯丙酰草胺)和350(式3.10，解草胺)。式3.11化合物的名称是MON 4660(Monsanto)，并描述在例如EP-A-0 436 483中。
式3.6化合物(AC 304 415)描述在例如EP-A-0 613 618中，式3.7化合物描述在DE-A-2 948 535中。式3.12化合物描述在DE-A-4 331 448中，式3.13化合物描述在DE-A-3 525 205中。式3.14化合物是已知的，描述在例如US-A-5 215 570中，式3.15化合物描述在例如EP-A-0 929543中。式3.16化合物描述在WO 99/00020中。除了式3.16化合物以外，描述在WO 99/00020中的其它3-(5-四唑基-羰基)-2-喹诺酮，尤其是在第21-29页的表1和2中具体公开的化合物也适于保护农作物植物抗式I化合物的植物毒害作用。
作为可通过式3.1-3.16安全剂拮抗上述除草剂损害作用而得以保护的农作物植物，可尤其提及的有禾谷类植物、棉花、大豆、甜菜、甘蔗、种植园农作物、油菜、玉米和稻，更尤其是玉米。“农作物”还指通过常规育种或基因工程方法使其对除草剂或除草剂类别耐受的农作物。
欲控制的杂草既可以是单子叶杂草，也可以是双子叶杂草，例如繁缕属、剪股颖属、马唐属、燕麦属、阿披拉草属、臂形草属、虉草属、狗尾草属、芥属、毒麦属、茄属、稗属、藨草属、雨久花属、慈菇属、黍属、雀麦属、看麦娘属、石茅高梁、双色高梁、筒轴茅属、莎草属、苘麻属、黄花稔属、苍耳属、苋属、藜属、番薯属、苘蒿属、猪殃殃属、堇菜属和婆婆纳属。
耕作区域包括农作物植物已经生长或者已经将这些农作物植物的种子播种的土地区域，以及准备用这样的农作物植物耕作的土地。
根据预期应用，式3.1-3.16安全剂可以在农作物植物种子的预处理中使用(种子或切条的包衣)，或者可以在播种前或播种后引入到土壤中。然而，其可以在植物出芽后单独施用或者与除草剂一起施用。因此，用安全剂处理植物或种子一般可以在独立于施用除草剂的时间进行。然而，也可以通过同时施用除草剂和安全剂(例如以桶混的形式)来处理植物。安全剂的施用量与除草剂的施用量的比例主要取决于施用方法。对于通过使用包含安全剂和除草剂的组合的桶混物或者通过单独施用安全剂和除草剂来进行的大田处理，除草剂与安全剂的比例一般为100∶1-1∶10、优选20∶1-1∶1。对于大田处理，通常施用0.001-1.0千克安全剂/公顷、优选0.001-0.25千克安全剂/公顷。
除草剂的施用量一般为0.001-5kg/ha，但是优选为0.005-0.5kg/ha。
本发明组合物适用于农业中的所有常用方法，例如芽前施用、苗后施用和种子包衣。
对于种子包衣，一般施用0.001-10g安全剂/kg种子、优选0.05-2g安全剂/kg种子。当在播种前不久安全剂以液体形式通过浸泡施用时，有利起见，所用的安全剂溶液含有浓度为1-10000ppm、优选为100-1000ppm的安全剂。
为了施用，有利起见，将式3.1-3.16安全剂或者这些安全剂与式I除草剂以及视情况而定的一种或多种选自式2.1-2.51的除草剂的组合与制剂技术中的常用制剂一起加工配制，例如配制成乳油、可包衣糊剂、可直接喷雾或稀释的溶液、可湿性粉剂、可溶性粉剂、粉剂、粒剂或微胶囊。
这样的制剂描述在例如WO 97/34485第9-13页中。制剂是以自身已知的方式制得的，例如通过将活性组分与制剂助剂例如溶剂或固体载体充分混合和/或研磨而制得。此外，在制剂的制备中可使用表面活性化合物(表面活性剂)。溶剂和固体载体的实例描述在例如WO 97/34485第6页中。
根据欲配制的式I、2.1-2.51和3.1-3.16化合物的性质，可使用的表面活性化合物是具有良好乳化、分散和润湿性质的非离子、阳离子和/或阴离子表面活性剂以及表面活性剂混合物。合适的阴离子、非离子和阳离子表面活性剂描述在例如WO 97/34485第7和8页中。制剂技术常用的表面活性剂也适用于本发明除草组合物的制备，这些表面活性剂特别描述在《McCutcheon洗涤剂和乳化剂年鉴》″McCutcheon’s Detergentsand Emulsifiers Annual″MC Publishing Corp.，Ridgewood New Jersey，1981，Stache，H.，″Tensid-Taschenbuch″，Carl Hanser Verlag，Munich/Nienna，1981和M.and J.Ash，《表面活性剂大全》(″Encyclopedia of Surfactants″)，Vol 1-111，Chemical PublishingCo.，New York，1980-81中。
除草制剂通常含有0.1-99％重量、尤其是0.1-95％重量的包含式I化合物、选自式2.1-2.51化合物的化合物、和式3.1-3.16化合物的活性组分混合物，1-99.9％重量的固体或液体制剂助剂，和0-25％重量、尤其是0.1-25％重量的表面活性剂。然而，市售产品一般是配制成浓缩物，最终的使用者通常使用稀释的制剂。
组合物还可以含有其它组分，例如稳定剂如植物油或环氧化植物油(环氧化椰子油、菜籽油或豆油)，消泡剂例如硅油，防腐剂，粘度调节剂，粘合剂，增粘剂，以及肥料和其它活性组分。在保护植物以对抗式I和2.1-2.51除草剂的损害作用的过程中，为了使用式3.1-3.16安全剂或包含它们的组合物，可使用多种不同的方法和技术，例如下列i)种子包衣a)通过在容器中振摇用式3.1-3.16化合物的可湿性粉剂将种子包衣，直至粉剂在种子表面上分布均匀(干法包衣)。在该方法中，每100kg种子使用大约1-500g式3.1-3.16化合物(4g-2kg可湿性粉剂)。b)按照a)的方法，用式3.1-3.16化合物的乳油将种子包衣(湿法包衣)。c)通过将种子在含有100-1000ppm式3.1-3.16化合物的液体中浸泡1-72小时，然后任选将种子干燥来进行包衣(浸泡包衣)。
给种子包衣或处理发芽的幼苗是优选的施用方法，因为用活性组分处理完全是针对目标农作物。通常每100kg种子使用1-1000g解毒剂、优选5-250g解毒剂，但是根据使得能够还加入其它组分或微量营养素的方法，该浓度限度可向上或向下改变(重复包衣)。ii)作为桶混物施用使用解毒剂与除草剂的混合物(二者的重量比为10∶1-1∶100)的液体制剂，除草剂的施用量为0.005-5.0kg/公顷。这样的桶混物在播种之前或之后施用。iii)施用到播沟中将式3.1-3.16混合物以乳油、可湿性粉剂或粒剂的形式施加到开放的播种种子的犁沟内。一旦种子犁沟已覆盖，即以常规方式采用芽前法施用除草剂。iv)控制活性组分的释放将在溶液中的式3.1-3.16化合物施加到无机物载体或聚合颗粒(尿素/甲醛)上，并干燥。如果需要的话，还可以施加上使得活性组分在特定时间内以计量的量释放的包衣(包衣粒剂)。
优选的制剂尤其具有下列组成(％＝重量百分比)乳油活性组分混合物1-90％、优选5-20％表面活性剂1-30％、优选10-20％液体载体 5-94％、优选70-85％粉剂活性组分混合物0.1-10％、优选0.1-5％固体载体 99.9-90％、优选99.9-99％胶悬剂活性组分混合物5-75％、优选10-50％水94-24％、优选88-30％表面活性剂1-40％、优选2-30％可湿性粉剂活性组分混合物0.5-90％、优选1-80％表面活性剂0.5-20％、优选1-15％固体载体 5-95％、优选15-90％粒剂活性组分混合物0.1-30％、优选0.1-15％固体载体 99.5-70％、优选97-85％下列实施例进一步举例说明了本发明，但不是限制本发明。式I除草剂、任选的式2.1-2.51除草剂、和式3.1-3.16安全剂的混合物的制剂实施例(％＝重量百分比)F1.乳油a) b) c) d)活性组分混合物 5％10％25％50％十二烷基苯磺酸钙6％8％ 6％ 8％蓖麻油聚乙二醇醚4％- 4％ 4％(36mol氧化乙烯)辛基苯酚聚乙二醇醚 - 4％ - 2％(7-8mol氧化乙烯)环己酮 - - 10％20％芳烃混合物 85％ 78％55％16％C9-C12通过用水稀释，可由这样的乳油获得任意所需浓度的乳剂。F2.溶液a)b)c)d)活性组分混合物5％ 10％ 50％ 90％1-甲氧基-3-(3-甲氧基- - 20％ 20％ -丙氧基)-丙烷聚乙二醇MW 40020％ 10％ - -N-甲基-2-吡咯烷酮 - - 30％ 10％芳烃混合物75％ 60％ - -C9-C12
该溶液适于以微滴的形式使用。F3.可湿性粉剂a)b)c) d)活性组分混合物5％ 25％ 50％ 80％木质素磺酸钠 4％ - 3％ -十二烷基硫酸钠2％ 3％ -4％二异丁基萘磺酸钠 - 6％ 5％ 6％辛基苯酚聚乙二醇醚- 1％ 2％ -(7-8mol氧化乙烯)高度分散的硅酸1％ 3％ 5％ 10％高岭土88％ 62％ 35％ -将活性组分与助剂充分混合，并将该混合物在合适的研磨机中磨碎，获得了可湿性粉剂，可以用水稀释以获得任意所需浓度的悬浮剂。F4.包衣粒剂a) b)c)活性组分混合物0.1％ 5％ 15％高度分散的硅酸0.9％ 2％ 2％无机载体 99.0％ 93％ 83％(φ0.1-1mm)例如CaCO3或SiO2将活性组分溶解在二氯甲烷中，通过喷雾施加到载体上，然后将溶剂真空蒸发。F5.包衣粒剂a) b) c)活性组分混合物 0.1％ 5％15％聚乙二醇MW 200 1.0％ 2％3％高度分散的硅酸 0.9％ 1％2％无机载体 98.0％ 92％ 80％(φ0.1-1mm)例如CaCO3或SiO2在混合器中将细研磨的活性组分均匀地施加到用聚乙二醇润湿的载体上。以该方式获得了无粉尘的包衣粒剂。F6.挤出粒剂a) b) c) d)活性组分混合物 0.1％ 3％ 5％ 15％木质素磺酸钠1.5％ 2％ 3％ 4％羧甲基纤维素1.4％ 2％ 2％ 2％高岭土 97.0％ 93％ 90％ 79％将活性组分混合，与助剂研磨，用水将该混合物润湿。将该混合物挤出，然后在气流中干燥。F7.粉尘剂a) b) c)活性组分混合物 0.1％ 1％ 5％滑石粉 39.9％ 49％ 35％高岭土 60.0％ 50％ 60％即用型粉尘剂是通过将活性组分与载体混合、并将混合物在合适的研磨机中研磨而获得的。F8.胶悬剂a) b) c) d)活性组分混合物 3％10％ 25％ 50％乙二醇 5％5％ 5％ 5％壬基苯酚聚乙二醇醚 - 1％ 2％ -(15mol氧化乙烯)木质素磺酸钠3％3％ 4％ 5％羧甲基纤维素1％1％ 1％ 1％37％甲醛水溶液 0.2％ 0.2％0.2％0.2％硅油乳液0.8％ 0.8％0.8％0.8％水 87％ 79％ 62％ 38％
将细研磨的活性组分与助剂充分混合，获得了胶悬剂，通过用水稀释可由其获得任意所需浓度的悬浮液。
实际上更经常将式I化合物、式2.1-2.51化合物和式3.1-3.16化合物单独配制，临用前在施用器中将其以所需混合比例以“桶混”的形式混合在一起。
下列实施例举例说明了式3.1-3.16安全剂保护农作物植物对抗式I除草剂的植物毒害作用的能力。生物实施例安全作用将测试植物在塑料盆中于温室条件下生长至4-叶期。在该阶段将单独的除草剂、除草剂与作为安全剂测试的化合物的混合物施加到测试植物上。以用500升水/公顷由25％可湿性粉剂(实施例F3，b)制得的测试化合物的水悬浮液的形式施用。施用4周后，使用百分比标度评价除草剂对农作物植物例如玉米和禾谷类植物的毒害作用，100％是指测试植物已经死亡，0％是指没有任何植物毒害作用。
在该测试中获得的结果证实了式3.1-3.16化合物可显著减轻由式I除草剂与一种或多种式2.1-2.51除草剂的组合所引起的农作物植物损害。安全作用的实例如下表B40所示表B40
当依据实施例F1、F2和F4-F8配制混合物时，获得了相同结果。
权利要求
1.选择性除草组合物，所述组合物除了含有常规惰性制剂助剂以外，还含有下列组分的混合物作为活性组分a)除草有效量的式I化合物或其农业可接受盐 其中每个R独立地为氢、C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基、C1-C6卤代烷硫基、C1-C6卤代烷基亚磺酰基、C1-C6卤代烷基磺酰基、C1-C6烷氧基羰基、C1-C6烷基羰基、C1-C6烷基氨基、二(C1-C6烷基)氨基、C1-C6烷基氨基磺酰基、二(C1-C6烷基)氨基磺酰基、-N(R1)-S-R2、-N(R3)-SO-R4、-N(R5)-SO2-R6、硝基、氰基、卤素、羟基、氨基、苄硫基、苄基亚磺酰基、苄基磺酰基、苯基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基；其中所述苯基自身可被下列基团单取代、二取代或三取代C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R45、NR46R47、卤素、氰基、硝基、苯基或苄硫基，其中后面所述的苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；或者每个R独立地为5-10元单环或稠合二环系，所述环系可以是芳环或部分饱和环，并且可以含有1-4个选自氮、氧和硫的杂原子；其中所述环系直接与吡啶环连接，或者经由C1-C4亚烷基与吡啶环连接，并且每个环系不可以含有2个以上的氧原子，不可以含有2个以上的硫原子，所述环系自身可被下列基团单取代、二取代或三取代C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R7、NR8R9、卤素、氰基、硝基、苯基或苄硫基，其中所述苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代，并且在杂环中的氮上的取代基不是卤素；或者每个R独立地为C1-C4烷氧基-C1-C4烷基或C1-C4烷氧基-C1-C4烷氧基-C1-C4烷基；m是1、2、3或4；R1、R3和R5分别独立地为氢或C1-C6烷基；R2是NR10R11、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；R4是NR12R13、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；R6是NR14R15、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；R7和R45分别独立地为C1-C3烷氧基、C2-C4烷氧基羰基、C1-C3烷硫基、C1-C3烷基亚磺酰基、C1-C3烷基磺酰基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；R8、R10、R12、R14和R46分别独立地为氢或C1-C6烷基；R9、R11、R13、R15和R47分别独立地为C1-C6烷基或C1-C6烷氧基；Q是基团Q1 其中R16、R17、R18和R19分别独立地为氢、羟基、C1-C4烷基、C2-C6链烯基、C2-C6炔基、C1-C4烷氧基羰基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-NHS(O)2、C1-C4卤代烷基、-NH-C1-C4烷基、-N(C1-C4烷基)2、C1-C6烷氧基、氰基、硝基、卤素、或苯基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者R16、R17、R18和R19当中的两个相邻取代基形成C2-C6亚烷基桥；R20是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R21R22N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；且R21和R22分别独立地为氢或C1-C4烷基；或者是基团Q2 其中R23是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4-链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R24R25N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；R24和R25分别独立地为氢或C1-C4烷基；且Y是氧、硫、化学键或C1-C4亚烷基桥；或者是Q3 其中R44、R37、R38和R39分别独立地为氢、C1-C6烷基、C1-C6卤代烷基、C2-C6链烯基、C2-C6炔基、C1-C6烷氧基羰基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6烷基-NHS(O)2、C1-C6烷基氨基、二(C1-C6烷基)氨基、羟基、C1-C6烷氧基、C3-C6链烯氧基、C3-C6炔氧基、羟基-C1-C6烷基、C1-C4烷基-磺酰基氧基-C1-C6烷基、甲苯磺酰基氧基-C1-C6烷基、卤素、氰基、硝基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-S(O)2O、C1-C6卤代烷硫基、C1-C6卤代烷基亚磺酰基、C1-C6卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C6烷硫基-N(C1-C4烷基)、C1-C6烷基亚磺酰基-N(C1-C4烷基)、C1-C6烷基磺酰基-N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者相邻的R44和R37或R38和R39一起为C3-C6亚烷基；W是氧、硫、亚磺酰基、磺酰基、-CR41R42-、-C(O)-或-NR43-；R41是氢、C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基-C1-C4烷基、C1-C4烷硫基-C1-C4烷基、C1-C4烷基羰基氧基-C1-C4烷基、C1-C4烷基磺酰基氧基-C1-C4烷基、甲苯磺酰基氧基-C1-C4烷基、二(C1-C3烷氧基烷基)甲基、二(C1-C3烷硫基烷基)甲基、(C1-C3烷氧基烷基)-(C1-C3烷硫基烷基)甲基、C3-C5氧杂环烷基、C3-C5硫杂环烷基、C3-C4二氧杂环烷基、C3-C4二硫杂环烷基、C3-C4氧硫杂环烷基、甲酰基、C1-C4烷氧基羰基、或苯基，所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C6烷硫基-N(C1-C4烷基)、C1-C6烷基亚磺酰基-N(C1-C4烷基)、C1-C6烷基磺酰基-N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者R42与R39一起为C1-C6亚烷基；R42是氢、C1-C4烷基或C1-C4卤代烷基；R40是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R96R97N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；R96和R97分别独立地为氢或C1-C4烷基；R43是氢、C1-C4烷基、C1-C4烷氧基羰基、或苯基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；或者是基团Q4 其中R30是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R31R32N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；且R31和R32分别独立地为氢或C1-C4烷基；R33和R34分别独立地为氢、羟基、C1-C4烷基、C2-C6链烯基、C2-C6炔基、C1-C4烷氧基羰基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-NHS(O)2、C1-C4卤代烷基、-NH-C1-C4烷基、-N(C1-C4烷基)2、C1-C6烷氧基、氰基、硝基、卤素、或苯基，其中所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4-烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者R33和R34一起形成C2-C6亚烷基桥；且R35是氢、C1-C4烷基、C1-C4烷氧基羰基、或苯基，所述苯基自身可被下列基团取代C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者是基团Q5 其中Z是硫、SO或SO2；R01是氢、C1-C8烷基、被下列基团取代的C1-C8烷基卤素、C1-C4烷氧基、C1-C4烷硫基、C1-C4烷基磺酰基、C1-C4烷基亚磺酰基、羟基、氰基、硝基、-CHO、-CO2R02、-COR03、-COSR04、-NR05R06、CONR036R037、或苯基，所述苯基自身可被下列基团取代C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7-环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR025R026、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR015CO2R027；或者R01是C2-C8链烯基或被下列基团取代的C2-C8链烯基卤素、C1-C4烷氧基、C1-C4烷硫基、C1-C4烷基磺酰基、C1-C4烷基亚磺酰基、-CONR032R033、氰基、硝基、-CHO、-CO2R038、-COR039、-COS-C1-C4烷基、-NR034R035、或苯基，所述苯基自身可被下列基团取代C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR040R041、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR043CO2R042；或者R01是C3-C6炔基或被下列基团取代的C3-C6炔基卤素、C1-C4卤代烷基、氰基、-CO2R044、或苯基，所述苯基自身可被下列基团取代C1-C4烷基、C1-C6卤代烷基、C1-C4-烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4-烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR028R029、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR031CO2R030；或者R01是C3-C7环烷基或被下列基团取代的C3-C7环烷基C1-C4烷基、C1-C4烷氧基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、或苯基，所述苯基自身可被下列基团取代卤素、硝基、氰基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷硫基、C1-C4卤代烷硫基、C1-C4烷基或C1-C4卤代烷基；或者R01是C1-C4亚烷基-C3-C7环烷基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C2-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4-烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR045R046、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基或-NR048CO2R047；或者R01是C1-C4亚烷基苯基、COR07或4-6元杂环基；R02、R038、R044和R066分别独立地为氢、C1-C4烷基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)-SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR049R050、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、-C1-C4-烷基苯基或-NR052CO2R053；R03、R039和R067分别独立地为C1-C4烷基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)-SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR068R054、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、-(CH2)t-苯基或-NR056CO2R055；R04是C1-C4烷基；R05是氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基、C3-C7环烷基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2H、N(C3-C6炔基)-SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2H、N(C3-C7环烷基)-SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR057R058、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR060CO2R059；R06是氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基、C3-C7环烷基、苯基、或被下列基团取代的苯基C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4-烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)-SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR061R062、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR064CO2R063；R07是苯基、C1-C4烷基、C1-C4烷氧基或-NR08R09；R08和R09分别独立地为C1-C4烷基、苯基、或被下列基团取代的苯基卤素、硝基、氰基、C1-C4烷基、C1-C4烷氧基、C1-C4烷硫基、-CO2R066、-COR067、C1-C4烷基磺酰基、C1-C4烷基亚磺酰基或C1-C4卤代烷基；或者R08和R09一起形成可被氧、NR065或S间隔的5-元或6-元环；R015、R031、R043、R048、R052、R056、R060和R064分别独立地为氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基或C3-C7环烷基；R025、R026、R027、R028、R029、R030、R032、R033、R034、R035、R036、R037、R040、R041、R042、R045、R046、R047、R049、R050、R053、R054、R055、R057、R058、R059、R061、R062、R053、R065和R068分别独立地为氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基、C3-C7环烷基、苯基、或被下列基团取代的苯基卤素、硝基、氰基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷硫基、C1-C4卤代烷硫基、C1-C4烷基或C1-C4卤代烷基；且R36是C1-C4烷基、C1-C4卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基、或被下列基团取代的C3-C6环烷基卤素、C1-C4烷基、C1-C4卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C4烷氧基羰基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4烷基羰基、二(C1-C4烷基)氨基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基-S(O)2O、C1-C4卤代烷基-S(O)2O、或苯基，所述苯基自身可被下列基团取代卤素、C1-C4烷基、C1-C4卤代烷基、C3-C6链烯基、C3-C6炔基、氰基、硝基或COOH；和b)协同有效量的一种或多种选自下列的化合物式2.1化合物 其中R51是CH2-OMe、乙基或氢；R52是氢，或者R51与R52一起形成基团-CH＝CH-CH＝CH-；和式2.2化合物 其中R53是乙基，R54是甲基或乙基，且R55是-CH(Me)-CH2OMe、<S>-CH(Me)-CH2OMe、CH2OMe或CH2O-CH2CH3；和式2.3化合物 其中R56是CH(Me)-CH2OMe或<S>CH(Me)-CH2OMe；和式2.4化合物 其中R57是氯、甲氧基或甲硫基，R58是乙基，且R59是乙基、异丙基、-C(CN)(CH3)-CH3或叔丁基；和式2.5化合物 其中R60是乙基或正丙基，R61是COO-1/2Ca++、-CH2-CH(Me)S-CH2CH3或基团 且X是氧、N-O-CH2CH3或N-O-CH2CH＝CH-Cl；和式2.6化合物 其中R62是氢、甲氧基或乙氧基，R63是氢、甲基、甲氧基或氟，R64是COOMe、氟或氯，R65是氢或甲基，Y是次甲基、C-F或氮，Z是次甲基或氮，且R66是氟或氯；和式2.7化合物 其中R67是氢或-C(O)-S-正辛基；和式2.8化合物 其中R68是溴或碘；和式2.9化合物 其中R69是氯或硝基；和式2.10化合物 其中R70是氟或氯，且R71是-CH2-CH(Cl)-COOCH2CH3或-NH-SO2Me；和式2.11化合物 其中R72是三氟甲基或氯；和式2.12化合物 其中R73是NH2或<S>NH2；和式2.13化合物 其中Y1是氮、次甲基、NH-CHO或N-Me，Y2是氮、次甲基或C-I，Y3是次甲基，Y4是次甲基，或者Y3和Y4一起是硫或C-Cl，Y5是氮或次甲基，Y6是甲基、二氟甲氧基、三氟甲基或甲氧基，Y7是甲氧基或二氟甲氧基，且R74是CONMe2、COOMe、COOC2H5、三氟甲基、CH2-CH2CF3或SO2CH2CH3，或其钠盐；和式2.13.c化合物 和式2.14化合物 和式2.15化合物 和式2.16化合物 和式2.17化合物 和式2.18化合物 和式2.19化合物 和式2.20化合物 和式2.21化合物 和式2.22化合物 和式2.23化合物 和式2.24化合物 和式2.25化合物 和式2.26化合物 和式2.27化合物 和式2.28化合物 和式2.29化合物 和式2.30化合物 和式2.31化合物 和式2.32化合物 和式2.33化合物 和式2.34化合物 和式2.35化合物 和式2.36化合物 和式2.37化合物 和式2.38化合物 和式2.39化合物 和式2.40化合物 和式2.41化合物 和式2.42化合物 和式2.43化合物 和式2.44化合物 和式2.45化合物 和式2.46化合物 和式2.47化合物 和式2.48化合物 和式2.49化合物 和式2.50化合物 和式2.51化合物
2.权利要求1的组合物，其中在式I中其中每个R独立地为氢、C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基、C1-C6卤代烷硫基、C1-C6卤代烷基亚磺酰基、C1-C6卤代烷基磺酰基、C1-C6烷氧基羰基、C1-C6烷基羰基、C1-C6烷基氨基、二(C1-C6烷基)氨基、C1-C6烷基氨基磺酰基、二(C1-C6烷基)氨基磺酰基、-N(R1)-S-R2、-N(R3)-SO-R4、-N(R5)-SO2-R6、硝基、氰基、卤素、羟基、氨基、苄硫基、苄基亚磺酰基、苄基磺酰基、苯基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基；其中所述苯基自身可被下列基团单取代、二取代或三取代C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R45、NR46R47、卤素、氰基、硝基、苯基或苄硫基，其中后面提及的苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；或者每个R独立地为5-10元单环或稠合二环系，所述环系可以是芳环或部分饱和环，并且可以含有1-4个选自氮、氧和硫的杂原子；其中所述环系直接与吡啶环连接，或者经由C1-C4亚烷基与吡啶环连接，并且每个环系不可以含有2个以上的氧原子，不可以含有2个以上的硫原子，所述环系自身可被下列基团单取代、二取代或三取代C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R7、NR8R9、卤素、氰基、硝基、苯基或苄硫基，其中所述苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代，并且在杂环中的氮上的取代基不是卤素。
3.权利要求1的组合物，其中所述组合物包含式Ia化合物作为式I化合物 其中R48是C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基、C1-C6卤代烷基、或5-10元单环或稠合二环系，所述环系可以是芳环或部分饱和环，并且可以含有1-4个选自氮、氧和硫的杂原子，其中所述环系直接与吡啶环连接，或者经由C1-C4亚烷基与吡啶环连接，并且每个环系不可以含有2个以上的氧原子，不可以含有2个以上的硫原子，所述环系自身可被下列基团单取代、二取代或三取代C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R7、NR8R9、卤素、氰基、硝基、苯基或苄硫基，其中所述苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代，并且在杂环中的氮上的取代基不是卤素；R49是氢、C1-C6烷基、C1-C6卤代烷基、卤素、或苯基，所述苯基可被下列基团取代C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基，且R50是C1-C6卤代烷基。
4.权利要求3的组合物，其中R48是C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基或C1-C6卤代烷基。
5.权利要求1的组合物，其中在式I中，Q是基团Q2或Q3。
6.权利要求5的组合物，其中在基团Q2中，R23是羟基。
7.权利要求5的组合物，其中在基团Q3中，R40是羟基。
8.控制有用植物农作物中不希望的植物生长的方法，所述方法包括将除草有效量的权利要求1的组合物作用于农作物植物或其场所。
9.权利要求8的方法，其中所述农作物植物是玉米或甘蔗。
10.权利要求8的方法，其中用所述组合物以相当于1-5000g活性组分/公顷总量的施用量处理有用植物农作物。
11.选择性除草组合物，所述组合物除了包含常用惰性制剂助剂例如载体、溶剂和润湿剂以外，还包含下列组分的混合物作为活性组分a)除草协同有效量的权利要求1的式I化合物和权利要求1的一种或多种选自式2.1-2.51化合物的化合物，和b)除草拮抗有效量的选自下列的化合物式3.1化合物 和式3.2化合物 和式3.3化合物 和式3.4化合物 和式3.5-化合物 和式3.6化合物 和式3.7化合物 和式3.8化合物 和式3.9化合物Cl2CHCON(CH2CH＝CH2)2(3.9)，和式3.10化合物 和式3.11化合物 和式3.12化合物 和式3.13化合物 和式3.14化合物 和式3.15化合物 和式3.16化合物
12.选择性控制有用植物农作物中的杂草和禾草的方法，所述方法包括用除草协同有效量的权利要求10的组合物处理有用植物、种子或其切条、或其耕作区域。
13.权利要求12的方法，其中除草剂的施用量为1-5000g/ha，安全剂的施用量为0.001-0.5kg/ha。
14.权利要求12的方法，其中所述有用植物是玉米或甘蔗。
15.选择性除草组合物，所述组合物除了包含常用惰性制剂助剂例如载体、溶剂和润湿剂以外，还包含下列组分的混合物作为活性组分a)除草有效量的权利要求1的式I化合物，和b)除草拮抗有效量的选自下列的化合物式3.1化合物 和式3.2化合物 和式3.3化合物 和式3.4化合物 和式3.5化合物 和式3.6化合物 和式3.7化合物 和式3.8化合物 和式3.9化合物Cl2CHCON(CH2CH＝CH2)2(3.9)，和式3.10化合物 和式3.11化合物 和式3.12化合物 和式3.13化合物 和式3.14化合物 和式3.15化合物 和式3.16化合物
16.选择性控制有用植物农作物中的杂草和禾草的方法，所述方法包括用除草协同有效量的权利要求14的组合物处理有用植物、种子或其切条、或其耕作区域。
全文摘要
除草组合物，所述组合物除了包含常用惰性制剂助剂以外，还包含a)式(I)化合物，其中取代基如权利要求1中所定义；和b)协同有效量的一种或多种式2.1－2.51化合物。本发明组合物还可以包含安全剂。
文档编号C07D405/06GK1396807SQ01804089
公开日2003年2月12日 申请日期2001年1月23日 优先权日2000年1月25日
发明者W·T·鲁格 申请人:辛根塔参与股份公司