一种针对高通量测序SNP所用生物信息分析技术的评价方法与流程

本发明涉及生物技术领域，尤其涉及高通量测序技术，具体涉及一种针对高通量测序SNP后所选择的生物信息分析技术进行评价的方法。

背景技术：

单核苷酸多态性(Single Nucleotide Polymorphism，SNP)分析是目前研究基因功能，寻找与疾病相关的基因及其突变位点，以及进行遗传连锁分析的一种重要的研究手段，高通量测序SNP是SNP分析方法中的一种经典技术。

近年来，随着基因组高通量测序技术的快速发展，极大地推动了生物医学、生命科学等领域的发展。目前基因组高通量测序技术已经应用于临床，譬如家系遗传病遗传学诊断、产前遗传诊断、胚胎植入前遗传诊断和肿瘤等复杂疾病个性化医疗等，同时越来越多研究者采用高通量测序来进行科研。

但是，高通量测序后生物信息分析的流程方法参差不齐，且信息分析后的数据结果的可信度也参差不齐，最关键的问题是数据分析完后，大量的数据堆积在一个文件中，很难直接评估分析结果的好坏，一般都要等实验验证后才能确定所采用的分析流程方法的好坏和数据的可靠性。

高通量测序技术要在临床广泛应用，除了测序技术的不断更新外，其中最为重要的环节就是生物信息分析的准确性和可靠性，如何评价大量数据经复杂分析流程出来的结果是否可靠，目前唯一方法是进行大量位点的实验验证，验证结果不好，再重新进行信息分析；或很多研究直接采用更严格的筛查条件来过滤更可信的SNP并实验验证，这样验证的准确性会很高，但不足之处是会导致很多可能有用的信息丢失。

因此，开发一种能直接评估信息分析流程方法好坏和数据可靠性的方法十分重要，对高通量技术在临床中的应用具有重要意义。

技术实现要素：

本发明的目的在于针对现有技术的不足，提供一种可以对高通量测序SNP后所采用的生物信息分析技术进行快速、直观、有效评价的方法。

本发明的上述目的是通过如下方案予以实现的：

为了快速有效地验证高通量测序SNP后所采用的生物信息分析技术是否准确，分析数据是否可信，本发明人从人类参考基因组hg19的保守区域中获得保守序列，并在该保守序列上人为设计SNP，然后对含有人为设计SNP的序列进行随机生成双末端测序序列(Pair-end Reads)，再对生成的序列文库进行验证和筛选，最后筛选得到134条核苷酸序列(如SEQ ID NO：1～SEQ ID NO：134所示)，这134条核苷酸序列每次随机产生的序列文库中都一定会包含有402个SNP位点；所述402个SNP位点是rs.hy00001～rs.hy0000402，具体信息如表1所示。

表1 134条核苷酸序列的402个SNP位点

本发明人用这已知402个SNP的134条核苷酸序列作为内参，对生物信息分析技术的合理性和数据可信度进行评价，具体技术方案如下所示：

一种针对高通量测序SNP所用生物信息分析技术的评价方法，该评价方法具体包括如下步骤：

步骤1

将如SEQ ID NO：1～SEQ ID NO：134所示的134条核苷酸序列随机生成100层双末端测序序列；

步骤2

将步骤1得到的所有序列和待生物信息分析的高通量测序序列一起采用生物信息分析技术进行信息分析，然后对信息分析结果进行检验，根据检验结果评价该生物信息分析技术的准确性和数据可靠性。

上述评价方法中，如SEQ ID NO：1～SEQ ID NO：134所示的134条核苷酸序列随机生成100层双末端测序序列，这随机生成的序列文库中必然包含有本发明已知的402个SNP位点(rs.hy00001～rs.hy0000402)，因此，将步骤1得到的所有序列和待生物信息分析的高通量测序序列一起采用生物信息分析技术进行信息分析，然后对信息分析结果进行检验，所述检验内容就是看信息分析结果中本发明已知的402个SNP位点(rs.hy00001～rs.hy0000402)的检出率和准确率，若402个SNP位点的检出率＜95％，则说明该生物信息分析技术的准确率和数据可靠性均不好，需优化；若402个SNP位点的检出率≥95％，再看其SNP的基因型是否和表1中402个SNP的基因型吻合，若基因型的准确率＜95％，则说明该生物信息分析技术的准确率和数据可靠性均不好，需优化；若402个SNP位点的检出率≥95％，且其基因型和表1中402个SNP的基因型相比准确率≥95％，则说明该生物信息分析技术的准确性和数值可靠性好。

上述评价方法中，将如SEQ ID NO：1～SEQ ID NO：134所示的134条核苷酸序列随机生成100层双末端测序序列，所述随机生成100层双末端测序序列采用本领域技术人员的常规操作即可。

上述评价方法中，生物信息分析所采用的模板为人类参考基因组hg19。

与现有技术相比，本发明具有如下有益效果：

1.本发明的评价方法适用于任何高通量技术测序数据的SNP分析流程方法和分析数据可靠性的评估，适用性广；

2.本发明的评价方法可以在SOP(标准操作流程)条件下直接对分析数据进行评估，相对于常规的流程(先信息分析后，再实验验证后才能确定信息分析流程的好坏及数据的可靠性)可省去大量不必要的验证时间和成本。

具体实施方式

下面结合具体实施例对本发明做进一步地描述，但具体实施例并不对本发明做任何限定。

实施例1 134条核苷酸序列的获得

本实施例给出如SEQ ID NO：1～SEQ ID NO：134所示的134条核苷酸序列的来源，试验中所采用的方法均为本领域技术人员的常规操作，具体步骤如下所示：

步骤1.寻找人类参考基因组hg19的保守区域

以人类参考基因组hg19中两两dbSNP(寡核苷酸多态性数据库database of SNP)间在同一染色体上间隔距离大于400bp并且落在外显子区域上的区域初步设定为保守区域，并按照dbSNP的位置提取两个SNP间的序列，得到的序列大于400bp并且不含有模糊碱基(N)，一共找到778个保守序列。

步骤2.Blat验证

用工具Blat验证步骤1的778个保守序列在人类参考基因组hg19的保守性，确保序列能够在基因组上唯一比对；将比对长度大于原序列的90％，同源性大于等于99％定义为与基因组比对匹配，将具有多重比对的序列去掉，则最终从这778个保守序列中得到232条唯一比对的序列。

步骤3.Bowtie2验证

将步骤2得到的232条序列进一步用Bowtie2验证，人类参考基因组同样为hg19，建模之后比对，最终从这232条序列中得到205条唯一能够比对到基因组的序列。

步骤4.去除Y染色体的序列

由于Y染色体研究不全，Y染色体上存在很多不确定的序列，为了排除不必要的干扰将Y染色体的全部去掉。

将上述步骤3得到的205条序列去除含有Y染色体的序列，则最终从205条序列中得到154条序列。

步骤5.设定SNP

以步骤4得到的154条序列为试验对象分别设定SNP，SNP的设定方法是：将每条序列的中间100bp的区域设定3个SNP，其中一个为杂合SNP，两个为纯合SNP；中间位置设置一个SNP(设定为杂合SNP)，然后在中间SNP的上下游50bp各设置一个SNP(2个SNP设定为纯合SNP)。

步骤6.随机Reads的生成、验证和筛选

将步骤5已经设定好SNP的154条序列每条随机生成100层pair-end reads，将全部生成的reads用bowtie2比对到人类参考基因组hg19；由于每个序列的设定文库也有可能是多重比对序列，所以要将有多重比对reads的产生序列去除，则最终从154条序列中筛选出135条序列。

步骤7.第二次排除和筛选

将步骤6筛选得到的135条序列重新生成pair-end reads，用bowtie2比对之后再用samtools和bcftools寻找步骤5设定的SNP，结果发现135序列中有一条序列因为snp位于重复碱基边缘而没有寻找出来(AAAA t/a TTTT)，将该条序列排除后，则最终得到134条序列，其核苷酸序列如SEQ ID NO：1～SEQ ID NO：134所示。

对上述134条序列进行重复验证，确保其每次随机产生的reads都能产生402个我们设定位置的SNP；所述402个SNP位点是rs.hy00001～rs.hy0000402，具体信息如表1所示。

实施例2高通量测序SNP生物信息分析流程和数据可信度的评价

本实施例待生物信息分析的对象为：

(1)样本：3个人的外显子高通量测序序列；

(2)内参：实施例1的134条序列。

本实施例采用生物信息分析技术是先用bowtie2比对，再用samtools生成SNP。

本实施例的评价方法，其具体步骤为：

步骤1

将3个人的外显子测序数据分别随机抽取得到90层pair-endreads；

将实施例1的134条序列随机生成含有设定SNP的100层pair-end reads；

步骤2

将步骤1的所有序列用bowtie2比对到人类参考基因组hg19(bowtie2参数为：bowtie2-D 20-R 3-N 0-L 20-i S,1,0.50)，将筛选出来的unique reads用samtools生成SNP(samtools的参数使用默认call snp的参数)，然后对生成的所有SNP进行检验，具体内容是检验我们设定的402个SNP(rs.hy00001～rs.hy0000402)在生成的SNP中是否能够检验出来，并且检验出来的SNP是否与我们设定的SNP基因型是否吻合，检验结果如表2所示。

表2设定SNP在真实数据模拟的敏感性与准确性

从表2可以看出，在所有生成的SNP中，402个SNP(rs.hy00001～rs.hy0000402)的检出率均大于97.5％，且准确性均达到100％，因此说明本实施例采用的生物信息分析技术的准确性和灵敏性都非常高，数据可靠性也很高。

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<213> 人类参考基因组hg19

<400> 14

GCTTAAGCTT TTAACAGCAT TTTAACCGCT CTAAAAATTA CCAGAGTAAG AAAAAGCTAG 60

GTACTTTAAA GTGAGTTTGA GAAACAAGTT GAAACTAAAA TTAAAATACC AGCCATTTAG 120

GTGCTTTCTC TGGCATCTAT AAAAGTAAAT TCTAGTGCCT GCCAAGTGAT GGATTATAAT 180

GGTCTCTAGC AAATGTGTGG TAAACATTCA TATGGCCATT AATTTTAACA TTAAATCGTA 240

GGTAGGGCAA TGTAGTAAAA TGAAAGAGAA TTAAGAAAGG TTTTGAATTC TTATAACATA 300

TCCAGCCATT TCAATTTTGA TTGAAATGAA CTACAAAGAA TAGTGTTTGT CCCTATGGTA 360

GCCTCAGTCT CTTTATCACT AACTTGGATT GAAATGAGTG AGGCCAACTC ACATTCCCAT 420

CAAACACTCT TCCAAGGAAA AGCAGAAGTA ATAATTGGAG GTAAAGTT 468

<210> 15

<211> 649

<212> DNA

<213> 人类参考基因组hg19

<400> 15

GTGAAGTCAC TGCTGCTCTG GGTTCGGGTT GGCGACTGAA GGCGGTACCG GCCTCCCGGA 60

ACAGCCCGGG GGAGGGCTTA GGTGCAGAAG GGCAGGCTGG CCGCGGCCGG TTTGGTCTGG 120

GGACCACGGG CTGGAGCAGG TGGGCAAGCG CCGGGACGGT GTGGGGAAGA CACTTGGCAG 180

CTTCTCGACC TCTGGTGTCC CTTCGTTTCT TCGAATTCCT ATTCATGCGC CGCACCCTTC 240

TCGGACCCCC AGCCCCTCGC TAAGGCTCTG GGGATGGGGG TCAAGTCTAG GCTCAATGGA 300

CCTCCCCTCC TCCACCCGGG TCACCACTCC TCGGAAATCC TCGCCCCACT CCCGCCTCAG 360

GCCTGTACCT CCTGGCTGTG ACGTGGTTTC TCAGCGACTG CCTCACCTCA GTCCCAAAAT 420

CCTCACTGCC TTAGATACAT ACGTGCCCCC AGAGGTTGGC CTGGGTTTCA CAGTATTTCC 480

CTAAGGGGGC AATATATTAA AGCTGTCCTT CGAAGTTAGT ACCCTGCCTG GTAGATGCCC 540

ATGGGATGAC AAAGAGGAGG AACAAGGGTT GACCAGATTA GGACTAACGA GAGAATAGTC 600

TGAGTCCAGA GACATTAATC TGTCTCTTTG TTTTGGCAGG TGGAAATTT 649

<210> 16

<211> 457

<212> DNA

<213> 人类参考基因组hg19

<400> 16

ATCCATTGAG TCCAGACAGT TGGGAAGTGC CTGTAGGAAA ATGGCGATGG CTGAGAAAAG 60

CCCGGAGGAG ATGCTCCTAG CTATGACTTC CAGCTTTCAA GTGCTCTGTT GCCTAACAGA 120

AGCTTGCATG CGATTAGTTA AAGTCGTGAA CTCAGAAACA CAGCGGCAGG AAATTGTAGG 180

GAAGATCGAT GAAGTGGTCA TAAATTACAT TTGTCTACTG AAAGCTGCCG AAGCAGCCAC 240

TGGAAAGAAC CCTGGGGACC CTAATGTTGG ACTCTCGGCG CGACACTCAA CCACCATGGC 300

CGCTCTCGTA AGCACACTGA CACGTTCTCT CAAGAGGCTT TTAAACAAAT AAATATGGAA 360

GTCACGTCAT AATCTACCTT TGCAAAGCCA TACATGAACT TTTATTTACT TTGTGTGTAT 420

GATGAACAGA TGTCTCCTTT CTTCTCTCTG TATATTT 457

<210> 17

<211> 433

<212> DNA

<213> 人类参考基因组hg19

<400> 17

CGGATATGGG GTTTGGGGTC AGAAACATCT TGATTAAAAT TTTGACTCTG CCATTTTCTA 60

GCCCTTTTAT GTTGGGAAAG CTACTTTTTC TAGTCTCAAT TTCCTCATAA TAAAATGAAA 120

ATCAATTATA AGATCGATTT CCATAGGGTT GTCATGAGTT TTGAGTAAAA ATGTGTATGT 180

AAAGTTCTTA CCACAATACC TGGCAGAGAG TAAGTATTCA ATTAATGTTA GCTATTATTA 240

TCATCATAAT CGTTGTGTTA AATATATTGC CCAAGATAAT ATGTGGGGGA ATGTTTGTTT 300

TATATGCATA TTGTATCCTG ACTGTGTGCA GAACACATTA TGTGTATTGC ATATATGTAA 360

AAGAAGTGTA CAAGGAAGTG GCCATCCTTG TTCAAGTTAC GTATCTAGTT AGAACAACTT 420

CCCAGTCCAT TGG 433

<210> 18

<211> 432

<212> DNA

<213> 人类参考基因组hg19

<400> 18

AGATTTAAGC GGGAACTGTC CGAGGTGCTT CAATGCCCCA TTTCCATGCG TGCCTTGTGA 60

TGGTGGTGCT TCAATTAATA TAGATCGTTT TGCTTTTCAA AACTTGACCC AACTTCGATA 120

CCTAAACCTC TCTAGCACTT CCCTCAGGAA GATTAATGCT GCCTGGTTTA AAAATATGCC 180

TCATCTGAAG GTGCTGGATC TTGAATTCAA CTATTTAGTG GGAGAAATAG CCTCTGGGGC 240

ATTTTTAACG ATGCTGCCCC GCTTAGAAAT ACTTGACTTG TCTTTTAACT ATATAAAGGG 300

GAGTTATCCA CAGCATATTA ATATTTCCAG AAACTTCTCT AAACTTTTGT CTCTACGGGC 360

ATTGCATTTA AGAGGTTATG TGTTCCAGGA ACTCAGAGAA GATGATTTCC AGCCCCTGAT 420

GCAGCTTCCA AA 432

<210> 19

<211> 411

<212> DNA

<213> 人类参考基因组hg19

<400> 19

AATCTAATAG CCTATAGTTT ATATTATTAT TTTGTATTAT TTGCACGCTG TTACATAGTA 60

TATAATGATA ATGTTTTCTA CAGTGAAAGA GCTATCCCGT CTTCCCTTTA CAACTGTCTG 120

AACTTTATTT ACTCATTAGT CAAGGTTCTT TGCAAGGCAG GTGATTAACT TAAATATCTC 180

AGTTTATACA GTGGTTTAAA AGACTTTTGT TATGGTAATA GGGAGAGAAA CTTGTCAGAT 240

AGGCTAAAAT CTAGATAATT CTACATATTC TGAGGAATTC ATGCTCCTGT GGCTCTTGCT 300

TATAAATATC TTGGAATGTT TCTGAATGCC TCTAAGCCTA TGTTCAGACT CTGTTGCGTC 360

AATGACTGGT AGTATTTCTT TCATTAATAT GTTTGTCATC TGGTCTGCAA G 411

<210> 20

<211> 406

<212> DNA

<213> 人类参考基因组hg19

<400> 20

CCCCAGGGCT CAAGAAAGCT GCCCAGGGCG GGGCTGATGG AGTCTTGATT GTACGTGCCC 60

CACTTGCACC ACAGCCTGCC TTGGGTTATA TACCATAGGA GCCACATAAC TCATTGGGCA 120

AAGCTTTAAA GTACATCCTC CTTCCAGGGG AAAGAGGAAC ACAACCTCGC TGTCTCAAAC 180

AGTTCCCTAA ATCAAGATGT TACATTCCCT AGGAGGGACA ACAACAAGGC CAACCTGTTT 240

CAGGCAGTTC CTCCATATCA GGATATTGCA TTCCCAGTGC ATTCTACAGT TATTCTTAAG 300

AACTACAAGC AAGGAAGAAG GGAGAACTGG GTCAGTCCAA GGCCACCTGG AGAACTGTCT 360

TGTACATGGG TTAGGGTAAA GTTGGCTATT CTAAAACTAA GCATCC 406

<210> 21

<211> 611

<212> DNA

<213> 人类参考基因组hg19

<400> 21

GGTGCTTGGC TCTTAGTGAA TGCACTAAAA TTCTTATTGA TAAATGTTGA ATAAACACAC 60

ACAAAAAAGT ATCAGAGAAA GAGAAAAACC CTACAATGGC AATAGAGGTG TGTGACAGTT 120

ATTGCTATCA ATTTTACATA ATATCTCATT TAAAAACAAC CTAATTATGC ATTGCCTGTG 180

AAAATAAAAG GATAAAATAA GATTTTGTAC ATACTGTAAG AATACAGTTG TGCTGTATTT 240

TTATGGATTC ATCAAGGAGT AAAATGTTCT GCTTTAGTAA ATTATATAGG TAACTGAAGT 300

GTTATTCCTT TAAAGAGCAA AATAATTTAT CACCATGTTT GGTGGAAAAT TTCTAAGTAT 360

TTATTACATG CCTAGGGGTT AGCCAACAAG ATATACCAAG CATGAAAACC TGTAAAACTT 420

AATAAAATGC TAAAATATGA ACATCACACT ATGGAGATTA TGCCTCACTA CTCAAAGAGT 480

GTGGCTCAGG AACCAGTGTA GCTTGGCCAT GCCCTGGCAG TATGTTGGAA ATGCCTGCCC 540

CAGACCAGTT GATGTTACTA AGAACGCCCA GGGGATGAGA ATGGACTTTA TTTACAGTTT 600

GGGAAGCACT G 611

<210> 22

<211> 447

<212> DNA

<213> 人类参考基因组hg19

<400> 22

GATTGAAGTG ACAGAATCTG AAAGAAAAGA ATATGATTGA GCTATTTGTT TTCCTGAACA 60

CCTCACCTTT TATGATGCAA TAAGTTACTC TGAGTTTCTT GGCAGAGTTT TTGACAGCTG 120

TTGCTTTCAA TGGATTCCAT TCCTGTATTC CTTATGGGAG GTTGTTTTTA AAATAGACTA 180

CTGCGATTGA AATGAACTCA ATATGTAGTT AAGTTATAGT TTTCTTCAAT GTATTTTTAG 240

TTACTTGGGT CACAAATGTT CAATTTCAGC ATATTTTAGG GTGAGTAATC AAAAATGTGA 300

ATTTGCCTTT GATTTCCTAC CACTGTCTGA GCTATCATAA AGCATTCTCT TTAGTTGTGA 360

TTTGATTCTA TAGTCTGTTT CTAAATGACA TTTGTCTGTT TCTTAAATGA TCTCACAGCC 420

ATGGTAATAA TAGATGTGTA CTCAGAA 447

<210> 23

<211> 443

<212> DNA

<213> 人类参考基因组hg19

<400> 23

CCAGCTCTGG GGCCTGGGAC AAGTTACTTA ACCTCTCTGT GCCCCCTCTT ATCTATTTAA 60

GAATATGGGT CTGGAAGTTC TTGTCTTACA GAACCATGTT GGTGGTCTGA GAGCAGTGAC 120

AATGAGGTGC TGTGGGTTGG GTGAGTGTGG GAGTGTCTGT CCTTTGTATA CTGCAGACTC 180

TCTTCTCTGG ATGTGCCAAC TGAGAATGGC TACAAGAACA TCAGAAAACA AGCCACCGCC 240

CTAAAGGTAC TTAGATCCAA AGAAAACCCA AAGCACACAT GTAAAAGCTG CTCAAACACA 300

TACAAAGGAA AGCATACAAT TATAGTCACC ACAGAGCATT TAATAATAAT AAGATGCCTG 360

AGAGAAAATG TAGCTGGGAA CCCACATGGG ATTGACAGAA GGACAGGACA CTTTGTCACT 420

TGCTTTTTCA ATAAACAGAT CAG 443

<210> 24

<211> 597

<212> DNA

<213> 人类参考基因组hg19

<400> 24

GAATTTTAAA CTGGTGAACT AAAGGAAATC TTGAGGTCAT ATACTGAAAT ATGAATAAAT 60

TAAAATAATG AATTCAGATC TAATCATTTT TATGACAAAT TGCAGCACCA AACAAACTAA 120

TAGCAACCCA TGGCTGTGAT TTGTTGTGTG GTAATTTGGA CAGAATGAAA AGCATGCTTT 180

TGATTTTTTT TTTAATCAGT GAGAGAAGTC ATCATTCTCA ACACAAAGCC CTGAACAACA 240

GCATTTGACA GTGTCCTTTA GATTTTAATT TTTTCAATGG ATTGCTTTAA AGAGAATGAG 300

TAGGGAAAAT AGTAGTTAAT TTTAGGTTAT GTTTTATATT AGGCTACTGG GGACATAAAC 360

GGTCATAACT AATGACTGTA ATCATTAAAC TCCTTAAACA GTTTAGAAAT TAGCTCCAGG 420

TTCTTAAACT AACAAAAATA AAACCTAAGC ATGCCACAGA GCTATTGATT AATCAGTAAG 480

TACCTGTAAT GAGTTTTCAG TGAAGCTTTC TCTCTGTGCT GATGAGATTC ATGCTACCTA 540

AAAATTAACA GAAATGACAC TGTGAACAAT GTAGTTGGAA AATAGGTATG TGTATAT 597

<210> 25

<211> 443

<212> DNA

<213> 人类参考基因组hg19

<400> 25

TTAACTACTG TCAGTCCTAA TGTTTTTCAA AAATCTTTGG AGATAATGTT AACTGCCTAT 60

CAAGAGTCAT TTTTCTCTGA CATAACTATG TAAAAGCACT TTGAAAAGCA TAAGGCACTA 120

TACAAGGGTA AGATAGTATA TTTTTAAAAG TACTGAACTG TAACCCAATT CCATATGTTT 180

TTGTGATTTC TGTCATGTAT TTTGAAACAA AAACATACAT AGCTACCAAG TATGTTTATT 240

ATAAAATTAT TCCCATAGTT CATAATTCAT TCTTAGAATG AAGAGTTATT ATACTGAAGT 300

GTAATGGCTA TTTACTCCTT ACTTATTTAT ACCCTGTCTT ATTTTTAAAA GTTTTAAGGT 360

ACTTTAGAGA TTAATGTATC AAGAAAAATA GGTGCTCAAA TGTTTTCTGT CTTGTCCACA 420

GAGGGGCACT GTTGGATTAT TTA 443

<210> 26

<211> 500

<212> DNA

<213> 人类参考基因组hg19

<400> 26

ATCTGCATTC TTAGATCATT AGGTCGTGGG GAATCTCTGG AATCTTCAAG TTTAACGCAG 60

AAATGCTTAT AACTGTCAAG GGGTACAGGG ATGTTTTACG CTGCTCTTGG GAACCTGGCA 120

CTCCTGACCC CAAGCACACT GAACCCGAGG CTGCTGAAAA GGCAATATAT CCAGGGATGG 180

GAATGGAGGG TATGAGGTTT CCTTCCTTAT ACACTCCCTT CCCTTAATTA TGCCCCCACC 240

CAGGAAGACC AAGGTGTTTG GGCTCCTTAA ATACTCGGAG GGAAATAACA GCCTCAAGTA 300

GCAAGGATGA GCACATAGGT TAAGAGGAAG GCAGGGGGAG GAAGGGAGGA AGAGAAAGGA 360

AGAGACATTT ATTTGTAATA CTATCAATGA TCAGTAATGT GATTTTTTGT TTTTGCATCA 420

CTTCTTCGGT ATTATCAACT CTCATTCTTT GTGGCTGTGC AAATCTATTA ATGTTTAGTA 480

GTTTCACTAT TAAACTCAGG 500

<210> 27

<211> 482

<212> DNA

<213> 人类参考基因组hg19

<400> 27

TTATTGAGTA GAGACACATA CACAGACATA TAATTTCTGT AACTAATACA TTCTTAAATG 60

TAGCTGGCTG TAAAAGCACA TGAACAAGAT TACTACTGAG ACTTCTTTGT ATCTCCTGGT 120

TGCAAACCTC TCTCAGAATT ATGAATCTTT CCAAACCCTT AATTATACAA GTCAAAACAA 180

AAAGTTTCAA AGAAGAAAAG GTCATTTTAA TTTGAAAGCC ACATTTCGCC ACAAGAAACA 240

AAATTAAGAA AACACACCAT TATATGGCAT AAAATGTGTG GAGTATACAT TCTAGTGTCA 300

TTTTTCCCAT TCAGATTTTT TCTTGAAGTC CATTAAAGTG ACATACTGGG TCCAATGTGG 360

GCCCCCTATT GTTTCAGAAT GCTATGGTTT TTGTTTGCGC CTGGTTTTAT TAAAGCTGGG 420

CAAACACAGG AGCAAACAAA GAAAACTCCC AAGATCCAAT AGAAAAAAAA TTAGCAAGAA 480

CA 482

<210> 28

<211> 431

<212> DNA

<213> 人类参考基因组hg19

<400> 28

TGTAAGAATT CATGATATGG TATCTTGGGC TTCTGGCATG CCTTACTAGA GAGAAACTAG 60

TATAAAGGAA GATCATATAT AACAGTAGAA AAATATTTGT GATTTTTTTC TTTTTTAAAA 120

ACTATTTAAG TAGGCACCCA CCCCATTCCC ACCCATGACC AAAAATGCAA AATAAGTACA 180

TCCCTTAGGT GTATACCTTC CCTTTTGCTT AGGGCAACAG TTAAGATAAA CTAATACACG 240

TATATGATTT TAAGAGTTAA AAACTCATCA CCCATAATCA ATAAGGATGC TAAGGAATGG 300

CAATACCTTG AAGCTTTTTT TAAAATTAAA AACCAAAGCT TTAGATGGTA AACTACACTT 360

ACAGAAACAC AAACCAAAAT CTTTATGCCC TTGCTTTGTA CGTGAAAGTT CTATTTTAAA 420

TACTTGTTTG A 431

<210> 29

<211> 459

<212> DNA

<213> 人类参考基因组hg19

<400> 29

ATGTTAACAA TTTTAAAATG CACTGTTTAG TGGCATTAAG TACTTTCACG TTGTTATGCA 60

ACCACTATCC ATCACTAGAA CTTTTTCATC TTGCAAAAAC TGAAATTCTG TACCATTTCA 120

ACACCAACTC CCCACTCCTC CCTTCCCCCC AGCCCCTGGT AACCACCATT CTACTTTCTG 180

TCTCTATGAA TTTGACTGCT GTAGATATAA GTGGAATCAG GCCTGGTGTG GTGGCTCACA 240

CCTGTAATTG CAGCACTCTG GGAGGCCAAG GCGGGAGGGT TGCTTGAGCT CAGGAGTTTG 300

AGACCAGGCT GGGCAACATA GTGAGACCTG TTGTCTACAA AAAAATTAAA AAATTAGCTG 360

GAAGTGGTGG TGCATACCTG TAGTCCCAGC TACTTGGGAG GCTAAGGCAG GAGCATCGTT 420

TGAGCCCAGG AGGTCAAGGC TGCAGTGAGC TGTGATGGC 459

<210> 30

<211> 540

<212> DNA

<213> 人类参考基因组hg19

<400> 30

ACACTCCCAG CCGGCCGCAG CCTGACACGC CGCGCGGCCC CCCAGTCTCC CGCGGCTGCT 60

CCCCCAGGCA TGGCACAGGG CCTCGCCTCA CTATGGCAGC AGCACGGCAC AGCACGCTCG 120

ACTTCATGCT CGGCGCCAAA GGTGAGGGCG CCCGCCGCCA CCTGCGTGGC CATCCCCGCC 180

GCTCCCGCCG CCTGGCGGGC TGGGGCGGGG GTCGGGCGTG GCGTGCGCCG CGGGCCGAAC 240

AATGCGGGCG GCCCGCGCGG CGCCGCACTC TCCCGGACTG CCACGCACAG CGCGCTGCGG 300

GGCCGCGTGC ACCGGCGGTC GGGCGGAGGC CGCGCTCCTG CTGGCTCCGC GCTCCGTCCC 360

GGCCGCAGCT CGGGGCCTGC AGGGGCAGTC CCGGGTGCCC GCCGGCCGCG CCGCCCTTCC 420

GGGCCCTGGC CGTCCACCCG CGCTCCCACG CGGGCTCGCC GCCTTCGCGC TCCCGCTCGG 480

GGAGTCCCCG GGCTGCCGGG CGCGGGCGGA CCCCCCATGG GACGAGGGTT GCAGGGACTG 540

<210> 31

<211> 400

<212> DNA

<213> 人类参考基因组hg19

<400> 31

CGACCCATTA AAATGTATTA GACATACACC TAGAAGCATT ATTTAACAAT GTTTAAATGT 60

TTTACTACCT GAAAATAATG GGATTCTGTA CTGTATTGGT GGTTGGATAG GCTCAAACCC 120

CCCTCCAATA GCTTAATTAG AAGCTTCTCT AAAATGCATG ATCATATGAT TCCTGTTTTG 180

GGAAGGTGTT GGGTAGAGTC CCTCCCCAGC TTGAGGGAAG CTAAATGAAG TTGGGAATAC 240

TGTGGACGTT AAAGAGCCAT GTATTGACAA AGTTGACATG GGGTTGGCCA AAATGGATCA 300

GTGATCTCTA AATTCCAGCG TGCTCCATGA AGAAGTTTTC ATGGGTCCTT AATAAAATGG 360

GGAGGAGTGG GAAGTAGTAT AATGTAGTGA ATTTTTCACA 400

<210> 32

<211> 629

<212> DNA

<213> 人类参考基因组hg19

<400> 32

GGCAATATGT AAACAAATGG GCATGGCTAT CGCTCCACTA AAACTTTTAT TCACAGAAAC 60

AGGCAACAGG CCCTAGTTTG CTGAACCCTC ATCTATAATT TTGATTGCTT TAGAATGGAG 120

CAAGAAAGAT ATTAAGAACA CTTATAATGC AATTTGAGTA CAGAATCCTT TTAGACTTTT 180

TTCAGTTGTT TTCACCCATA TCTAATTCAC AATCCCTATT TTTTGAGTGA TTTGCCTTTG 240

GCTTTCATAG AAAGAGCGGC TTTCTCCTTC ATGTCAGTTT ATGAAACATT AAATTGCAGA 300

AATACAATAA CTGGCATAAA CAGGTTTGGG GACAGAATCA ACTCTTGGTA AGCAGACAAT 360

TCAACCGATG GGAGCAATAT TCATGGGCCT ACCAGAATGC AGCCTACTAG TCAAAAGTAT 420

GCAGCAGCTG TGGACATCAG TCAGTATATT TTCCACAGAA AATGAAGACC ATCTCTAATC 480

TGGTGAGTTG GGTAAATGAA AGTTTAAGAG AGCTTCTGCT GTAGTATACT TCTGTAAAAA 540

AATCCAAAAA ACTAAAACTA TGATTATAGT TGAATGTTTT CACATAACAT AACATGAAAA 600

ATAACATATA TAGAGTTTAT TTTAAAACT 629

<210> 33

<211> 403

<212> DNA

<213> 人类参考基因组hg19

<400> 33

TTTTAAAGTA ATTTTTCTAA TGCTTCTTTC TGCAAGAGGG CCAAAACCAG AACATACTGT 60

TTTAGTGTCT TTGTTAACAA AAATAATTAT TTATAACTTT TATATTAGAA CTGTATATTT 120

GATATAAAAA TATGTTTATA ATTAAGCTAT CCAAATTTGT ATATTAAACA GAATTAACAC 180

AAGTTTGCAG CATGAGATTA GTTGCAAACT TATTCCCTAT TATTAATACT TCCTTCCATT 240

GAACAGTCAG TAAGTAATTC CCTTAACATA AATCCATCCT AAGTGTGTGC ACAAATCGGT 300

TAGCCCATCA GTTAACTTCA GAGGACCAGG TGATAACCAG ATGAATTCTA CTCCTCTACT 360

GAGACATTTA GATATTTATA TAAATCTATC GCTATTCCTT TCT 403

<210> 34

<211> 446

<212> DNA

<213> 人类参考基因组hg19

<400> 34

CCTCAAGATT GTTAGGAGGT AATTTTCCAT TGAATTATCA ACTGTGATTT TTATATTGCC 60

CTCCAAGTGG TAGAAGAAGA TTGCAAAGTC CATGTTATGC TAGGTGCACA ATAAATCTAG 120

TAATAGCCCC ACACAGATCT CATCATTGTT GCTACTTCCT TTTGTATTTT CATCAGGTAT 180

TTTTTTAACT GTAGGGTTTT TACTTTTTTC TTGGAGCAGA GAGAACAGGC TGTAAATGGG 240

TTGCCAACAT AAGCTGGCTG AGAAATAAAA GAAAACAAGA CAGTTGTTCA TAAAGTTTCA 300

TTTTGTATGC ACTGATGGCA AATTCATTAG GTCAGTTAAG GGAAATATTT GTACCACTTC 360

CAAACTTTTC AGCGTTGGAT AAAATGATTG ATGAGGCAGG CAGAAGGAAT GTAGGTTTCA 420

GGTGTGTCAT TTCCTGCTGC TTCCAG 446

<210> 35

<211> 564

<212> DNA

<213> 人类参考基因组hg19

<400> 35

AATTGGCCTC AGTTGTTCAT CAGTGAAAAT GCTCAGTTTG GGGTGATACC ACATAAATAG 60

CAGCTTTCAG ATGACTCCCC ACATTGGGTC CAGAAGTTCT TTCATATAGG CTGAATATAA 120

TAACCATCCT ATATACAGAG CTTTATGGAA CACATGCAGT TTTTATCGTC CAAGAACCCC 180

TCAAGATGTG TTTGGTAAAT GCTCCAAAGT CTTACAGCTA GAAAAGGACA AAACCAGGAT 240

TCAAACCCAG GGTTTCACTT TCTAAGTTTA TTTATTCAGT ATTCTAGACT AGAATCTGGG 300

GATACAATAG TGAACAAAAT AAACTTTCCC TCAAAGCTAC CTTCTGTTTC CATTTGCTGT 360

TCCTTTCACA ATTCATCCTT GAGACCTGAA ACCTAAAGCA CTCAGAACTG ATACTCTAGT 420

TCATTATCAT ATCAGTTCCA TTTCTAGTAA CTTCAGAAAA ACAAGACCAC TTTCAGGCCT 480

ATCTGCCCTT TTAAGTTCTG ATAGGTCTGA TGATGATGTG CTAACCATTT TGATTTGTGT 540

GTCAAATCTA AGCAAAGACC ATGT 564

<210> 36

<211> 427

<212> DNA

<213> 人类参考基因组hg19

<400> 36

ATGAGTTTTA TTGCTTTCTG GGACCTCTAA CCCAGGACCA CCCCTGATTC ACCAACTTCT 60

CCTTCTTCTC CTCTTTAAAT ATTATAGTTC ATTGTGATAT GTTTTTCCTG TATCTGCTCT 120

ATCATGTGAC CTCCTTTCGC CTGGGAGGGC AGATTTTCTC CTTATCTCTT CCATCCATGT 180

CTGTTCTTAG CTAAGAGTTC CAGCCTCAGT ACAGCTGGAT TACCCTTTGG ACAGAAGGGC 240

AGACAACCTC AAGGTCAGCA GCAACAGAAG TTGGGCCTAG TAGTCAGATC ACAAGTGAGT 300

GTGGCTATTC ATGAGAATAG GGTGGTGGTG GCATTTATCC TGCTTCCCCT CCATAAATAA 360

ACCTGGTAAT TTTATTTTTA ATGTTACAAA AAAAGTTGAT GCTACATTAA ATGTTTTACC 420

CTCATCC 427

<210> 37

<211> 440

<212> DNA

<213> 人类参考基因组hg19

<400> 37

TTTTGTACTG AGTCTTCAAA CTCTAGTGTG TATTTTATAC TTACTATACA TCTCCAGTCT 60

CGAAGTAGCC ACATTTCAAG TGTATAAGAG CTGCATGTGA GTTGGCTATT GTATTGGACA 120

GTCCCATTCC TGTTTCCTAG TATTGATAAA GTCTTCCTAC CTTCCTTCGT TGTTATGGGA 180

GAAAATGTAA ACAGAACCTG CCTATTACAC GAGAGCTGCA ATATTTCCCC AAATGCAGCC 240

CAGCAGTACC ATGAGCTGCC CTGTGGAAAA ATTTAATCTG TGATTAAATA AGTTAGGAAA 300

GTTTTATTAT TTTACCCCCT TTTGAAGATT ACATGGTACA TTAACATATT AAAGATTGAG 360

TAAACTCTCC TGGGTAAAAA AACCTGTTTG ACGTTGTTTA GTTGTTGAGT TCTGTGTCTA 420

TAAGAATCCT AGAAATTGCC 440

<210> 38

<211> 519

<212> DNA

<213> 人类参考基因组hg19

<400> 38

CTCATTACCC CGAAGAGCAG CTTCAATCAT CTACTGCTTA GCTGCCTCCA CCCCACAACT 60

CCAAAATTAC TGATTAGGAA GCATAACAGA GCTGTCTGAC GACCAAAAGC AGGCGCCAGT 120

GGCCTCTGGG AACAGGCAGC AGAGGACAAT GAGAGATCCT GGGCTTCAAT GAAGGAAAAC 180

GGTGGCTCTC TCCCCATTTA TTACTGAGCA AACTATTTGT TTTAAAAGCA CATAGAATGC 240

TGCTCCACCT GGGCCCACAC TCCTGACATT TAGAGTTAAA GCAGTATATA GACTGGGATT 300

AATTCTCCTT CATAAATATG AAATAATAAA TTAAGGACGA AAGTGCACTG AAAGGCCGCT 360

TTAGGGGCTA ATCTTTTAAA GGGCGGCAAT GCTTCACTGA GCCAGGTTGC CTGTTAAAAC 420

TGTAAATCAA GAGCGGCCTA CTAGGCGGGA AGCTCTTTCT CTCCCACCCC TTTTGGGCCC 480

ACGGTGGCTG TGAGAAGTTG AGGGGGGCTT CAGCATGGG 519

<210> 39

<211> 442

<212> DNA

<213> 人类参考基因组hg19

<400> 39

CGTTCTGCTG AAGCTCTCAC TTTTCTTCTA ATTCTGAAAG TACTTTTATA CATTCTGAAA 60

TGGCATTTCA GCAGATGGAA AAATGAAGGT GGCAAATCAG GACCAATTTC TTATTTCAAG 120

GTTAAATTAA TACTAAACCA GACTATTAAT GAAAACATCT TCATCAAAAT TAACTAGAGA 180

GTTGGTAGTT CTCTGAAACT TTGTATAAAT TTTATTTATT ACTGTAAATA CTAAAATCAC 240

ATTGAAAACA CCTTAAAGTT AAGTCCCAAC CCGATTATTA GAGAAAATCA CTTGGGCATC 300

CAGTCCCCTT GATCGAACCT GGGTAACAAA AGAGGCAAAA GACATGATTT GTGATGAAAC 360

TTACTATTCA AATGCTAAAT GTTTTCAAGC TTTAATAAGG TATATATCAA TTCCAAGTAC 420

CAAGCATAAT ATAAAAATTC AA 442

<210> 40

<211> 624

<212> DNA

<213> 人类参考基因组hg19

<400> 40

CCTGTGTGGT GACAAACATC TCTTTCCATT TTCTTTTGCT CAGTCCATTT GCACAGGTTC 60

GAGGGAGTTG ATGGAGGGTC AGACGAGAGG TGGTGGGAGC TCAGGATTTT CTATTCCCAC 120

AAAGAGCTAA GACTTAGGAG TGCTGGCCCC AGAGATGGTG CGGCCCTCTT TCTACTTCTG 180

TTTCTGTGGG CTCTGTCTGC CCACCTGCTG CACAAAGCAA GGCAGGGGAA AGACCGGATG 240

GGAACATGGT GGTGAATATC CTCTTTTTTT CCCTTTTCCC CCACTTCCTG GATGTAGGTG 300

ACAGCTAAAC TTCACCCACT AAGCTGGAAA ATCTGGGACT CCCCATAGCT CCAAGTTTAA 360

GGCAAACTGA TGTGTGTGTG CACAGGCAAA GCCAATCAAG CCATGAGCTT GGAGGAGAGT 420

CCTGTATCCA GAGATTCCAA ACAGAGAGGG AAATCTTATT TCTAAAGGAG TTAGAAAAGG 480

AAAGGCTCTG GCAAATGAAA TGATCTGTGA TTAAAGCTTG TAGCCTTTCT GTAAGCTGCA 540

GTGAGAAGGA AAGCATCTTT TAATAGAAGA ATTAATTAGA GGCGCAGAAC AAGAAAGCCA 600

CGCTCAGGGA CCTTTAACTT ATTA 624

<210> 41

<211> 816

<212> DNA

<213> 人类参考基因组hg19

<400> 41

TGGAAGAATG TGACTTCATG GAAGAGTTAT GAGATGGTTA ATGTCTCTAA AGCAACAAGG 60

ACAGATGATT CCCCTGTGCC AAGGGATACA GCAAGAGGAA GGAGAGACCA CAGGTGGCCT 120

CCAGTACACC CGTGGCCCTT GGGCGCATGG CTCTGTGCGA GTCAGACGTG GTCCAGCTGT 180

GCTCTGGCAG GCTACTTTGT CACCCTGCCA ACTGATACTC ACTCCTGGGC CTTCAAAGGT 240

TCAATGAGCA TCTAACAAAT TATACAATTG TAAAGATTAT CAGCTTGGAA GCCTGAACAA 300

ATCTATAATG AAATGAAGGA CCCAAAGGCA TTTAATTATT GAACACATAA AAGGAAGTAT 360

ATTTAAAAAA AATTGGTCAA ACTGTCCTGT TAGTTATCAT TTTAAAGGAA TTTACAGGGC 420

TGTTATAGAT GATTCTTTTG GAATATTTCA GTTTATAGCA AATGCCTAAA CTGGTTTCTT 480

CATTGCACAG TATTTTCTCT TAAAATGGGT GCTTTAAAAC AATTACATAC AGATTAAAAA 540

TCATTTCTTT GCTTAATTAA AACGTTAATA CTCTTAGACA ACACAGATCT GAAATGGTGA 600

AACCAGCAAT TCCCCCCACC CCACCTTACA ACAAATTAAA TTGAGACAAA ATTACAAACA 660

CATTTCACTA CATGATTATT ATTAATAAAA ATCAGTTTCT TTTTTTTTAT AAAGTTGCCC 720

AAAATGCAAG GGATGTGCAT AGGTTTACAA CTTAGTCATA ATAGCATTTT ATTCTTATTC 780

CCCTGGGTGT GCCCCATGAA CGGAATGTAG AATGTA 816

<210> 42

<211> 494

<212> DNA

<213> 人类参考基因组hg19

<400> 42

AAGAGAGAAA AAAGGCCTTT AAAAATTTAT GACTGTTTTG TAATCACTAC ACTAATTATT 60

TCAAATAAAT AAAGGAAAGA AAGATATCCC AATATTCCAA TCCATAAAAT CAGACTCTAA 120

AAAGAATGTA GTGTTCCACC CCCAGTCAAG GTAACAGAAT CATTGTTTAT TATTATTAAA 180

ATAGATTATA GAAAGCAGCA TCTATTTTGT GCAGTTTTTA GGGGCCTTGG AAATAAAAAG 240

CTATGATTTC CAAAAATATA ACATTCCAAA GGATTGAATA ATACATACAT TTAAAGATAC 300

ATTTTATTAA AGTTTAGGAG AACTGATTAA AAAAGATACT GTCTCTTTAA ATTAGTGTGT 360

AATTGTTTTT CTCCTCCTAT CTATTCGGAC ATGACAATAA TTATAAATGT AGGTCACACT 420

ACAACTAGGT AGTCTCTAGG GACCATGACC TGCTGACACA AGGCCGATAA CAAAGAGGCT 480

TTTCCACAAA TGAG 494

<210> 43

<211> 417

<212> DNA

<213> 人类参考基因组hg19

<400> 43

TTCCCAAAGT GCTGGGATTA CAGGCATGAG CCACTGCACC CGGCTTGAAT CATCCTTTTG 60

TCCAGTATTA TATCCATGCT GTATATGCTA CCCGCCCACT AGTCCCTTAG CTGTCTCAGT 120

TGTCAGATTG ACTGTCATGG GATTGCAGTG CTTGCATTAA AGCTACCCTT ATTGTATAAT 180

GACCCCAAAG TGCAAGAGTA GTGATGTTGG CAATTTGCAT ACACCAAAAA TAAGTTATAA 240

AGTGCTTCCT TAAAGTGAAA TGGTTAAAGT TCTTGACTTA ATAAAGAAAA AAAATGTATG 300

CTGAGGTTGT TAAGATTTAC AGTAAGAATG AATCTTCTAT CCAAGAAATT GTGAAGGAGG 360

AAAAAGAAAC TTGTGCTAGT TTTGCTGTCA CATCTGAAAC TGCAAAAGTT GTGGCCA 417

<210> 44

<211> 403

<212> DNA

<213> 人类参考基因组hg19

<400> 44

GGTGCATGTT ATTTCACCTG ACATACCAAT TTTTAATCAT CTATCATTGG ATATTAAATT 60

GTCTTATTTT TTCACTACTT TAAATAATAC TGCTGTTATG GAAGATACTC TGAAAATTTT 120

AAATCTTATA TTGCTTCACC ATAAAATTAT TACTCTTTAT TAAAACATGG AGAATTTTAA 180

GTTCTAAGCA CTGTTCCTAA GGAAAGTATG TAAAAGCTTA CTATGTGCCC TTTCTGTAAT 240

GGCTTTGCAT TTTTGCACTG AAGATATTGA TGAATAATAT ACGTAAGGTC TCCTGTTTGA 300

GATCTTTGTT TCAGGGATCC TGATGACTCA TCCTCTCTTA CCCTATTTCA GGAAGCATTT 360

TTTCTATTTG TTTAGGAAAA TAATCTGGGA GTTTGCCCCA CAT 403

<210> 45

<211> 453

<212> DNA

<213> 人类参考基因组hg19

<400> 45

TTAAAAGGAA TCTGAAATTT AATTCTATTT TGATAAAACT AAGACTGAAA ATAACCACTT 60

GTAAACATTC CTATGATTGT TACTAAAATG TATTTTCATG TTTAAAATGT TTTTGGATAT 120

TTTTGGGTTA ATAACTACTA CATTGAATTG CATGTTAAGG TGCAGAAATA ATACATTAAA 180

AGATTTTCAC TTTAAATTAA TTAGTAATAT TGAGCGCTCA CCCTGTGCGT GGCCTTGTGC 240

TAACCATTAG CACTGCATCA TTTCAATTCT TTTATAAGGG CATTCAATAC TACAAAATCA 300

ACATGATTTC ATAAGGTGCA AATAAAAGTT GGTGACAGAT TTAATATAAT TTTGATCACA 360

ATTTACAAAT GATCTTTGCA AATAGTGGTC AGACGGCATT AGTTTTTCCC TTAGTTAAGC 420

TAAATTAAAG GGACTCCATC CTGTTATGAT TAT 453

<210> 46

<211> 526

<212> DNA

<213> 人类参考基因组hg19

<400> 46

CCTGACTGAC AAGCATAAAA GGCTAACTTG TGGATAGTGT TTACAAAAGT ACAAAAGTAC 60

TACTTCCAAG GAAAATGCTC TGATTCTCTG TTTAGGCATT TGTGAAGGAT TCCAGAGCCT 120

TTCCCAAAGT GAGACCATTT CTGGGGTATT TGTACCAGGT CAGGGTTTTT GTGTTGTTTT 180

CAAATAAGTT TGACTAAAAT AAGTTTGGCT GACAGTTTTT GTATACCTGC TTTAATGTTT 240

ATAAAATTTT TATTGAGGTA TAATTAAAAT ATAGTAAAAT GCACAGAGGT TAAGTATTCT 300

TACCTGCTTT AATTTTGAAA CAGATTTTTA TTGTCAAACA GAATTTGAAA GCATGTGTTT 360

AACACATGGA TATAATTTAG CTTTGTGTCA CCTTTGAATC TGAGGCAGTT TCCCAAACAA 420

AAAGGCTGGA GCCATTTTTC AGAAGTTGCT TATACCCTGT TCCCAAACTA TCAGCCTTGA 480

TTAATTTCTA GTAGGAAGAG AATAATTACA TTTGCGGGGG GGGGGG 526

<210> 47

<211> 413

<212> DNA

<213> 人类参考基因组hg19

<400> 47

TATGGCCTGC AGCTTATGCA AATGACAGCT TTGGGGACAT AGGTTAGAAG GCATGCATAC 60

TTCTTATAGG GTATGACTCA TCTGCTCTCC CAGCAGGGAA TTAATAATGA GACAACTACT 120

ACCTTTATAT GTCTGTATCA TTCAATGACT ATATTTCTGT AACATAGCCT AGAGCTAGGC 180

CTAATTTCTC AATTCATAAA GTTATATCTT TAAATTTAAA AATTCCATTG CACTTAAAAT 240

ATATATACCA TGAGGACTTC CCAAGGGAAA AGAAAAAAGT TTTTCATGGA AATCTTTTCT 300

ATGTCTTAAG TGCCAATGAT CACAAAAACA GATATCTGCA TTCCCAAGTA GGTTTTCTGC 360

CTTGATGTCA GTGCCCTGCC AGTGTTTGGA CAATGAAAAC TCTTCTCCTC AAC 413

<210> 48

<211> 403

<212> DNA

<213> 人类参考基因组hg19

<400> 48

GCTAGAGAAC TCTTTGGGAT CCCTTTTATA AGGGCACCAA TCCCATTCAT GAGTTCTCCA 60

CCCACATTAC CTAACTACCA CCCAAAGGCT CCACCTCCTA ATACCATCAC ATTGAGGATT 120

AGGATTTTAA CATATGAATT TTGGGGGGGA TGCAATCATT CAGCCCATAA TACCCTCTAA 180

CATATTAATC ATAGTTATTT TTAACTCCCT GTCTGATAGT TCCAACTACT AGGTCAACTG 240

AGTCTAGGTC TGTTGTTGTC TTCTCTTGCT CTTTTGCATC TAATAATTTT TGGCTGAATG 300

TCACAGATGT TGTATGTAGG ACAGTAGAAA CTGAGGTAAA TAGTAATTAT TCCTGGAAAC 360

AGCCATGGTT GCCCTTTTGA TAGGCCATTA GCATGGGGAG ATT 403

<210> 49

<211> 554

<212> DNA

<213> 人类参考基因组hg19

<400> 49

GAATCCATCT AATCAGGAGT TGGGCTGAGT TTGTGTTTCT TTGTTGCCAG TGTTACCTTT 60

GCTGTACCAT AGACTTAAAA TTCCTCTATT GTTATCTTAT GCTTGAGGTA GGCACTGGTT 120

TGCCCAGAGA ATTTTTATTT TTCCCAGACC ACACTTGCCT TTAGGCCTGT AGGCCTTTCC 180

TGTGTGCCTG CATCTCAGGG AGGGTCTCTC TCCATGTTGT TGCCTCTATG TTAGTAGTAG 240

ACAACTGTTA TTACTTGGTT CTTGCTGACC TGGTGAGTTG GGGGGCAGGG GTTGTCTTGG 300

GCCAGCCTCA GTTTTTGTCA GGCCATGAAT CCCTGGGTCT TGAGGGTGGG ATTTTTTAGT 360

GATCCTGCCC TCTTCCACTG GTAGAAGGCC TTTAATGATC TGGGCCCAGG ATGATTTCCT 420

GCCCTTTTAT CATGGGTGGA ATTTTTTTTT CCATTTCCCT CACTCTAGTC ACAGTGAATC 480

TTTAACTGTG TCCTGAGGGC AACAGGGTTT GCTGCACTTC TTTTAGTGGC TTAAGGATTT 540

TGTTCTGTAG GGGA 554

<210> 50

<211> 482

<212> DNA

<213> 人类参考基因组hg19

<400> 50

GCCTCAGAAG CCTAAGAGAG AGCCCTTTGC AGCAGGCTGC CTGGGTTCCT GAGTCACTTG 60

GAAGAGTTCA AAGCCTTTGC TGATGATAAA TCCCCTTGCA GAGGGCAGAG TGGGCTACAG 120

TGTCAAGGGT TTTGCAAATT GCCAAGACCT TGATTATAAA GTGTTCGCTA AGACAGGAAC 180

TTTTTCATGT TGCAGAAGAC TTTTGCAATC TGCAAAGGAG CTGCTAAGAC TTAGGGAGCT 240

TTGGCAGAGG GTCTTCAGGG GTTACAGTTC CCTTTGTCAG CCAAGGAAAG CCCTTTGCTG 300

AGGCCACTGT TCCTCATGCA GTGGGGCCCC AGCCCCAGGC ACACACGTCA GAGCCTTTTA 360

GAGAGAAAAG TGCCCAGTGA GTGTGCAGAT TCCCACTAAT GGCTTCTTGG CATTGCAGTC 420

CCAAGGGTGC GCTTCGCCAA TGATGACCGA CACCGCCTGG CCTGCTGCTC ACTCGACGGC 480

AG 482

<210> 51

<211> 420

<212> DNA

<213> 人类参考基因组hg19

<400> 51

GGAGATTGAG GGGTCTGCTG CAGGCCTCCT CCCTGCTGCC CCAAAGGTAT GGGGAAGCAA 60

CCCCAGAGCA GGCAGACATC AGAGGCCAGA GTGCCTAGCC CGACATGAAG CTGGTTCCCC 120

AACCACAGAA ACTTTGTACT AGTGAAAGAA AGGGGGTCCC TGGGCTACGG GCTGAGGCTG 180

GTTTCTGCTC GTGCTTACAG TGCTGGGTAG TGTTGGCCCT AAGAGCTGTA GGGTCTCTTC 240

TTCAGGGCTG CATATCTGAG AAGTGGATGC CCACATGCCA CTGGAAGGGA AGTGGGTGTC 300

CATGGGCCAC TGAGCAGTGA GAGGAAGGCA GTGCAGAGCT GGCCAGCCCT GGAGGTAGGC 360

TGGGACCAAG CTCTGCCTTC ACAGTGCAGT GAAGGTACCT AGGGCTCTTG GGAGCTCTGC 420

<210> 52

<211> 614

<212> DNA

<213> 人类参考基因组hg19

<400> 52

CGAAACGTTA GCGGTCGGGT CTGGGCAGGG GGTGGAGCTG GTTGAAGGAA CGGGGCAGTC 60

CCCTGAGGAG CGGGGCTGGT TGAAACGCTA GGGGCGGGAT CTGGCGGAGT GGAAGGTACC 120

GGTCCGGCCC GATAAGGGGT GGAGTTAAGT GAATCGTTAA GGGTGGAGTC GAAACCGGGG 180

TCGGGGCCGG GGCCGGCTGA GTGAAAGGGT GGGTGATTAT CCCGGGAGAT AGGCCGAAAG 240

GGCAGGTTCG TGAAGGAATG GGGTCTGGGC TGGGCTTAGA GGGTCTGGGA ATGGGGCTTA 300

GGAGAGTAGA AGGGGCGGTG ATTGGTTGGA AAGGGCAGGC CCTAAGACGG ACTGTGTGAG 360

CCCGGGGGCT CATTGCTCCG TGAAAGGGCA AGACCAGGGA AAGAGAATCG TGTAAAAGGG 420

GTGGAGTCTA GCGGGCCGGG CGGGGCCGGG TAGAATGGCC ACCTGAGTGG AGGGAGAAGG 480

CCTGAGAGAG GCGGAGTTTG GAAGGCTGTG GAGAATCAGA TCGCGTAAGG AATGGAATCT 540

AATAGAGGGG GCGGAGCCTG GAAAAGGGCA GAGAGGTGGG GTCCTCAGGG CACACTAGCC 600

CCCTCACATA CCCA 614

<210> 53

<211> 403

<212> DNA

<213> 人类参考基因组hg19

<400> 53

GAGCCTGCCC TGGACAAACC AGGGCAAGCT AAACGCTTTG GGAAGCAATG TCATGGTCTC 60

TGCAGCCAGC CTTGGGCAAG TCGCTGAGCC TTTCTGAATC TGTGTCATCG CCTGTAACAA 120

GGGGACCAGT AAACATAAGT TCCTCAGGAG AGTTTGATGT GTGTCAGGTG CTTAGAACAG 180

GGCCTGATAT ATAATCAGCC CATGATGAGC TATTACTGTT ATCATGATCT GATTGTGTGA 240

ATAGATGGTG GATGTGTGGA CAGAGTGATC GGGGTTCCCC CAGGGGCTTC CAGATTTAGA 300

GGCCTAGTGC TATGTGGCTT GAGGAAAGCT AGCTTCCAGA GCAGGTATCT GAGCTGAACT 360

TTAAGAGGAG AAAAAGAGTG AGTCAGATGA AGAGGGTGAC TGA 403

<210> 54

<211> 488

<212> DNA

<213> 人类参考基因组hg19

<400> 54

GCCAGGGGTT AGACCAACTC AATCTCATGA TGCCCTTCTC CAACCCCAAA CTCTCCAGGA 60

AGGATGGCCT CACCACAATT AAGAGCACTC AAGATAAAAG CAGAGTCCCC TCACTAGATA 120

AAAAGCAGCT AAAATAACAG AGTCCCCTCA ACAGAATAAA AGCACTGAAA AGTAACAGGA 180

TCCCCTTACC AGAGAAAGAA TACTCAGGAT GGTAACAGGA TCCCCTCACC AGAATAGGAG 240

CCCAGAATAA GGTTAGCACA CCATTAAAAG ATGGACTTTA TCAGAGGGCA AGGCTGAGAA 300

TCCCCAGTAT TAGCAATCGA TCATCTTATA TAATGCAGTA TGGGTCAAGG ATTACAGGAC 360

ACCCCACCAC TGGAGGCCAA AGGTCACAAG GCCATCAAGT AAAAACAATC CCTCCAGGGA 420

GATTTAGAGA AGCCTTACCA TCAAAGTCAG TGTAGGGTTC ATCATGAAGC AGGGCACCAG 480

AACCAAAA 488

<210> 55

<211> 427

<212> DNA

<213> 人类参考基因组hg19

<400> 55

TGTGTCATCT CAGAGCGTGT CCTCAACTGT GAGACATGGG CAGCCATCCA CCATCACAGA 60

GTTGTTGTGA GGACTTGAAT AGAGTAAAAG CCATCAAAAT ACTCAGTTCC AGCCCACTGT 120

CAGCGCTCAG TATTTGTTTG TCAGTCTGAT CCTGGACCTC CAACCAGAAT TGGGGTTTCT 180

ACGCTTTAGA AACCCCAAAT CAACTTTTTT TTGTACCTCT ATGAAGAAAC TGAGCAAACC 240

CAATTCATTC AGTCATTCCT TCAACAGATA CTGAGCACCA ACTGTATACC CAATCCCAGT 300

GATGGAAACT TAGAGAAGGA TCACAGCATC TGCCCTAGAC AGTATCTTTG GAAAGCTCAT 360

GAGTTCGATG ATTCCATTTG ATACTTTTAT CCCAACTCTG TTTCTTCTGC AGGGATCGAC 420

AAAAAAA 427

<210> 56

<211> 621

<212> DNA

<213> 人类参考基因组hg19

<400> 56

TATTTTTCTC CTCACCCCTG CGGAGGTGGA GCACAGGTGG CTGGTTTAAG TGGGTTAGGC 60

TGGTGGAGTT CCAGAGTTGA GAACCAGTGC TTGGAATCTG AATTGTGCAC CTCAATGAAC 120

CAGCCATTGG ACTGAATCAG GTAATTGAGC ACGCTAAGTT TGTCTGAGAA GTAGGGAGAG 180

GCCAGTTTTC TCTTGATAAG TGGGAAGGGA CAGTTAACTA AAGGTATGAG TCAAGGGTGG 240

GGTGAAGATG CAAGGCTGAC CAGAGAGAAC CTCTCTGGGC ATTGGGGTTT GATTAGATTT 300

GCCCTGACTG GGAGAAGGCA TTTTTGAAAA ATGTGAATTA GTATTTGGAG CGATTTAGGA 360

ATAGTTTGTT TTCATGAGAA ATTTGCAAGA AGAACCACAG GAAAGCACAG GCTTCTAGCC 420

TTCATTTCTC CAGGCCCATG TTTTTTCTGA TCACTTCAAT GCCCCTCTGT ACTCAAGGGA 480

AAAGGGCAAG ATGGGAGATT TGAAGGTGAC TTGAGGACTG ACCCAACAGC CTGTCCAGAA 540

GATCAGGCCA AGATGGAGCT TGTGGGGAAG GGCCTAGGCT GTGACTTAAT TGTCAGGCAG 600

TCCCTAGTTC AGGCATCTAA G 621

<210> 57

<211> 579

<212> DNA

<213> 人类参考基因组hg19

<400> 57

ATAGACTTCC AGAGCTCTTT TGCCCCCTCT GCTCCCATGC ACCCTCCCCT TCCAAGTCCT 60

TTAGCAAGGC CTGGATGTTT AGGGAGAAAG TGGTCCAAGG CTGCTGACAA GAGGGACCAA 120

AGGGGGTGCT GGGTTCCCAG GGAGCAGGGA TGTTTAATTA CTATGTCATG TGCAATGTTG 180

TTTTAGGCCA ACCCTTGCCC CAAGCCCAGT CTCTTCTCCC TCCCCACCAT GTCCAGACCT 240

CCCAAATGGT TCTTGTGCAT CTGTTGGAGA AGTCAAGGGA GTAGGGAGAA GGGCCCCAAG 300

GATGGGCCCA GGTTAGGTGA AGAGTAAGAT GTGAGCTGAA CTCCTCGAAC TGAAGAGACC 360

CACACTTGGT CACATTCTCT CACGCTGCCT TCAGGATCCC CAGCCCCCAA CTCTTCTTCC 420

TGAGGATGGA AATCCACTCC AGCCCCACTA GGACTGATGT GGGTGCCATA CAGGCAGGAG 480

CAGCCCACCA GGAAAGTGTA AGGAGGGAGC TGAACTCCCC AGAGTAGCTG GACCACAGAG 540

ACTTGGGTCA GAGCTGATTT CAACCCCAGA ATTGTCTCT 579

<210> 58

<211> 461

<212> DNA

<213> 人类参考基因组hg19

<400> 58

TAGGTATCTC ACAGCTCAGT GATACTGGTT GCTTTTAGAG CTCCAAAGGA TTCATCCCTC 60

TGTGGCTCCA GAAAGAAAAT TCCAAGCCAT GTAAATTTAC TACTATCCCT TCCTTTGCTG 120

GATATAGAAG TCCTACCTTC AAGACGTTGT GAAAGGTTGG GCAGGTCCAA GAGAAGGGGG 180

ACCACATTAA GGGAGCTGAT TCCAAAGAGG AGGTTTTTCT ATACTTTGTT TCTACTTCTG 240

TCTGGTTAGA TGTACACTCT TGTCATTTTT CTTTGGTTTA TGTAAGAAGT ATCTGGGCAG 300

GGGTCAAGGC ATTGCAGGGC TCCCTCCCCC TGAAAATCAT GGATTCTCTT AATCTGGGAC 360

AGATTAGGAC TAAATAGTCT GACACTGTTT TCAATTTCCT ATGATCTGGT CATTGTAAGT 420

GGGCAGTAAG CAAATAGCCT TCTGGTTGTC TGGGCAAAAA T 461

<210> 59

<211> 570

<212> DNA

<213> 人类参考基因组hg19

<400> 59

ACAAAAAAAA ACCTCAGGAG GCCACAGCTG TCCCCACAAC CTCATAGGTT TATCATATAA 60

GTCTTTGATA ATGAGTATCA TTATAAATGC TCAGAAAAAC CAAAGCTAGA GCTTTTCTAT 120

AGGACCTTAT GTGATGATAC CCAATTTCTG ACAGCTACTG CCTTACTAGG CTCCCAGAGG 180

AGATAAATAA ACTATTGGTG CTATATCTTC AATTTGAGAC TAGGACCTAG TCTTACTGCC 240

ATTCATCTTT GACCAGAACT TCTCCAGAAA CAGACCACTG AATCTGAAGT CCCAGAAACA 300

GGCAGGGAAG GGGAAAAGAT GGACACAATA GGACATCCCA CCAAAATCCT GGAGAAATCT 360

AGGGTAAGCA TTTATATCCT CCTCTAGCTT GGGCCTAAAA TCAGAAAAGT AAAAGTTTTT 420

CCCTCTTCCT GGTTTGGTGA AGCCATCTTC AGCTTATCAG TCCTCTTTCC GTTGTGCCAC 480

AGTTTCTAGC TTTTGCTCTT GTAAGTGGTT CTTCTCCCTA TTATTCATAG GGAGGTAGCG 540

GTTACCATTA TTACACTCAT TGCTGTCTCT 570

<210> 60

<211> 447

<212> DNA

<213> 人类参考基因组hg19

<400> 60

AGGTTAATGT CAAAAAGGAT TAAAATTAAC TTTAACAACA TTCTATATAA TGCTACATTC 60

CCCAATTAAG AAAGGAGAGT TCACATATAC AACTAAATGT TAAGTGTGGA GAAGAGGGTG 120

AAATTCTGCA TACTTCATAG TAAATTATGC TGAAAGTTTA TTAATTGCAT AAACTTCCTG 180

AGTGGCTCCC ATGCTGCACT AGGTCTACAT GCTTAATATA TCAAACAAAT TATAGCTTTA 240

GGTGATTGAG CATGACAGAC CTTGAACAAC TGCACTTTCC AGTTAGTCAC TGTATCTGCT 300

GAGGGTATGT TCTGGACCGC AAACCTCAAT CTCAAATCTT AAGTTACAGT GGAAAAGAAA 360

TTCAACTTAA AAAAAAACTA GAGGATGACA AGCACGCATT TAGGAGTTTA TTTTATACTG 420

GCACATTTTT TTCTCAGAAC CCAGTTT 447

<210> 61

<211> 448

<212> DNA

<213> 人类参考基因组hg19

<400> 61

ACTTTAGTGT AACCTAGTTA CTATCCCAGG CTCCTTCATA TATTGGCTGT CAGGGTTCCT 60

GACCAATGTT TGTGTTGATC TTTCACATAC AAAGACTATT TCCAGGGTGA CCTGAAGGCA 120

TTTGGTTCCA TAAAAATTTC ATACTAATTT CAATTCAAAG GATTTTATCA AGTTTGAGTG 180

TTACTATCTT ACGATCTGCA TTTTTAAAAT TTCAATCTTA GAAATTACAC CTATCAAATC 240

AAAGGCCTTT TCTACACACC ACCCCCCTTT TCTGATTCCT CTTCTAAACA AAGGGAGGGG 300

GGGAACAAGT CCTTGATAAA CTACAGATTC AAAAAACAAT CTTCTAGAAA ATGGCCTGCA 360

TACCACCTCA GATAGTTCAA GTTTTTCTGA CCCAAACAGA AGATAAAATA ACTGAATCCC 420

AAAATGATGG CAAATATACC TCAGGAAT 448

<210> 62

<211> 525

<212> DNA

<213> 人类参考基因组hg19

<400> 62

CTAATATATG TTGAATGATA GGCCATTGCT GAAGGATTTG TCAAATATTT CGCTGTGGTA 60

GTTAAAGCAA TTTCAACCCA TTGCCCTTTA GGCACACAGA CGAGAAATGC ATCTCTAATA 120

AAAAATGCAA AGTTATAGGC ACTGGATTGT CTAATTCAGG TACTTTCTTA CCATTTGTTT 180

ATTTTATAAC TAACTCCTAC ACCTAAATCC TATATTGCCA CCAATTTCAA TTATTCTTCT 240

GCTCTCCACC CCCAAATCCC CAAAGCATAT TTCACAGAAG CACATGGCTC TCCACTTAAA 300

CACAGATGAG AGTGATGATC CCTCTCATCT CAAACTGTTG GCTAGCACTG GGAAAAAAGA 360

GGCAGACCAG ATTTATAATC TGAAAGAATA CTGAGAATCA AGGCAAAAAA GCAAGTTTCA 420

CAGGTAGTGT TTACTTGTGC ACCCAAAACA GCACTGAAAA CGAGGTAGTT AAACAAAATT 480

AATTGGACTA GAATTAAATC TGGGGTTCTA AAATGATATA TCCCA 525

<210> 63

<211> 765

<212> DNA

<213> 人类参考基因组hg19

<400> 63

CATTACCACA TATGGAGATA CAGTACTATT CATCAGACTT GCACTTTGAG AAGTAAACAT 60

GGTGGCTGGA CATACAGACT ATCCTCTGAA TAAACTTTAC AAGCAGGATG GTTAAGTACA 120

ACCATTTTCT CCTCTACAAG AAGGAAAATG AAAAGGACAG GTTTGTGTGT TTTTTGGAAA 180

GGAAGGCCCT TTTTATATAG TAGGCTCTTT GTTAAGAAGG GAATTTCTGA GCTTTACCTC 240

AAGTTAATTA TTTCTGGGGA GGAAAAGTAC CTCAGACAAG GATGAAAATA GCACTATTAT 300

ATGATTTAGC AAAATTATGA AATAATGCAA AAGCCCTGGA TAGAAAACTA GCCAGTATTT 360

ACAGTCAAAG TGACTATAAT CTGAACCAAA CATGTAAGTC ATGGGAAAAA ATAATTTTAA 420

TAAAACCCCA CAGTGATGAG AATAACATTG TTTTCTCCAT TTCTGCACAA GCTCACTTTT 480

TTCTGTATTT TTAAATGTAC ACATGTTATA TATACATAAT GTATACATAA CATATATGAT 540

AACCCGGTTA CTGCAGTCAG CATGGAGACA GCAGTACACT ATTCACCATC TTCAAACTTT 600

AGAAGACTAC TTTTCTTTCC AGCAAAAACC TGAAAAGATT GTAAATATTA CAAGGCACTG 660

CAAGAGTCTG CAGGCAAACA AGAATGATGA ATTATATGTG GAATAGAGGT GGTGGCCAAA 720

GGCAGAACAT AGGATGTAGA GCAGTCATTA ATACATGTAA TTGTA 765

<210> 64

<211> 423

<212> DNA

<213> 人类参考基因组hg19

<400> 64

ATAAAGAATG AGCAGAAGGA CTGCAAGCAC AAACCCATTG CTCTACTGTG GAAATTAAAG 60

GTCTTGTTTC TCCTTGGAGG GGGAAGAGGG AAAAAGGAAG GTGGGAAGGC CTCAGATATG 120

GGTCCCTGCC ACTTCCTCAA TCAGGCCATG GGGCTCAAAT ACCAAAGCCA GAGCTTCACA 180

GCTGTGATCT AACTTCTCTA AGCCACCAAA TTATCAAGAG CCCCTTTTCA GAAGCTAAGA 240

ATTTGTATGA ATAATGCAGT TCTAAATGGG AAAGTCCCTA ATGTTTTCAT TTTTCTCAGA 300

TGAATTGATT CTGCCTAGGA AGTAATTTGA CTTCCTTCAG GATATGAGAT GGGGCATGGA 360

ATCTCAAGAG GGGAAGGTGG GTTAGTTAGT GTTTAGGCCT TGCAGCCATT TCACAATTGG 420

ATG 423

<210> 65

<211> 440

<212> DNA

<213> 人类参考基因组hg19

<400> 65

CCAAATTTTG AGCAAAGGAA AAGAAATCCT AGAAACAATG GCATAGAAAC TAAGGAAAGA 60

AGGGTGTGTT TTGTGAAAGA AAGGAATTTT GTTTATAGAG AGTATTTTCA CACATGAAAG 120

TGAACAGTGG AATATAAAGC ATAAAAGGCA GGATGGAGCC GAGCCATGGA GAACCTCGAG 180

TGCCATGTGA AGAGAATTTG ACTTGTGATG AAGAATCAAG TTTCCCCTTC TACCATTCAT 240

CAGCTACATC TCCTTTTTAA GTAACCCATT TTATCCTTCA GAACCTCACT TTTCTATTTC 300

TGGCCCTGGA CTTCTAAGCC TTGTTTCTTT GTCATCCAAT TCCAATATTG ACAAATAATT 360

CTAAACAGCT ACTTTTAGTT TGTATGTTTA ACGTCCTGTG AAATATTCCT GTATTAACCC 420

CAAGCCTTTT GATGATAAAG 440

<210> 66

<211> 818

<212> DNA

<213> 人类参考基因组hg19

<400> 66

CTGGGCTCCC AGCCATCGTA ATCACATTTC TGTACCTGGA AAAAAAATGT ATCTTATTTT 60

TGATAATGGC TCTTAAATCT TTAAACACAC ACACAAAATC GTTCTTTACT TTCATTTTGA 120

TTCTTTTAAA TCTGTCTAGT TGTAAGTCTA ATATGATGCA TTTTAAGATG GAGTCCCTCC 180

CTCCTACTTC CCTCACTCCC TTTCTCCTTT GCTTATTTTT CCTACCTTCC CTTCCTCTTG 240

TCTCCCCACT CCCTCCCTCT TTGTTTCCTT CCTTCCTTAT TTCCTTTAGT TTCCTTCCTT 300

AGCCGTTTTG AGTGGTGGGA ATCAATGCTG TTTCACTCAA AAGTGTTGCA TGCAAACACT 360

TCTCTTTATT CTGCATTTAT TGTGATTTTT GGAAACAGGT ATCAACCTTC ACAGTTGGGT 420

GAACAAGTGT TGTCCTACAG ATGTCCAATT TATTTGCATT TTTAAACATT AGCCTATGAT 480

AGTAATTTAA TGTAGAATGA AGATATTAAA AACAGAAGCA AATTATTTGA AGCTCTCTAA 540

TTTGTGGTAC GATATTGCTT ATTGTGACTT TGGCATGTAT TTTTGCTAGC AAAATGCTGT 600

AAGATTTATA CCATTGATCT TTTTTGCTAT ATTTGTATAC AGTACAGTAA GCACAATTGG 660

CACTGTACAT CTAAAAATAT TACAGTAGAA TCTGAGTGTA ATATGTGTAA CCAAAATGAG 720

AAAGAATACA AGAAATGTTT CTGGAGCTAG TTATGTCTCA CAATTTTGTA GAATCTTACA 780

GCATCTTTGA TAAACTTCTC AGTGAAAATG TTGGCTAG 818

<210> 67

<211> 458

<212> DNA

<213> 人类参考基因组hg19

<400> 67

CCTGCAGCTG CCTTTCCAAA CGGGGTCTTC ATGCCTGCGA AGAGGAGCAC AGTTGCCAGG 60

TGGACCGAGA AAGGAAATTA ACAAAATCAA TGCATAACAC GGAGAGCTTT TTCTCCTAAT 120

CAGCGCACCC AGTAAACCCA CACCTGTTTT TCCCGAAAGC TAGATAGCAA AGCTGGAAAT 180

CAAGGCACCC TGGCTGAGTG CCTGCAGTAA CCTTCCTCCC CAGCTCAGTC TGGCTAAGAT 240

CTGCGGTTCG GTGAAATACG AAGCGTTTCC CCATTCCCCT CGCCCTGCTT CCAACACTAC 300

CCGGCCAGGA GGCGCAGATT CCCCACCGTC CCGGATTGCG GGCCTCAAGT GCACAAATCG 360

GACACCTCGC CGTTGCCTCC GCAGTGAGCC TATGGAGGAG GAAAATCAGC GGGCGAGCAG 420

CCCGGTGCTT GCAAAAGCTG GGAGAGGATG ATCCATAG 458

<210> 68

<211> 441

<212> DNA

<213> 人类参考基因组hg19

<400> 68

GTCTATAGCT GTATAGGTCA CTAATCTGAC TTGATGATTT TAAGTCACAT TTCATAGTTT 60

TAACTAGTTA TGAGAGAGAA ATTATATGGC AATATTTGAA CATTGCTTTC TTAGGCACCA 120

GAGCAAAGCA ACTCTGTTTC CTTTGCACAT TTTACCTGCC AACATTTATT AACAGTTCTT 180

ACCTTCCAAG TCTCTTCACC TTAGCAAATT AGGGATCAGG TTGCAGTCTT CTGCAGAGAA 240

ACTGATGGTT AAGCTCAAGT TCCAAGCATA GTATGTGTGT GCTACACAAG CTCAGAAGAG 300

TTTGACAAGG ACCAGGGGAC TTACTACCAC AATCCACTTC CCTTATCCCA GGAGAGATGG 360

CCAAACCCAT GTGGCATTAA ATGGTGAATA AAAAAGCTTC ACTCAAGGAG GGACTATTGG 420

ATGCTCTTTG GACTTCTGAC C 441

<210> 69

<211> 408

<212> DNA

<213> 人类参考基因组hg19

<400> 69

CCAGCCCCAG CCCGGCTCCA GCGACAGCCA ACGCCTCTTG CAGCGCGGCG GCTTCGAAGC 60

CGCCGCCCGG AGCTGCCCTT TCCTCTTCGG TGAAGTTTTT AAAAGCTGCT AAAGACTCGG 120

AGGAAGCAAG GAAAGTGCCT GGTAGGACTG ACGGCTGCCT TTGTCCTCCT CCTCTCCACC 180

CCGCCTCCCC CCACCCTGCC TTCCCCCCCT CCCCCGTCTT CTCTCCCGCA GCTGCCTCAG 240

TCGGCTACTC TCAGCCAACC CCCCTCACCA CCCTTCTCCC CACCCGCCCC CCCGCCCCCG 300

TCGGCCCAGC GCTGCCAGCC CGAGTTTGCA GAGAGGTAAC TCCCTTTGGC TGCGAGCGGG 360

CGAGCTAGCT GCACATTGCA AAGAAGGCTC TTAGGAGCCA GGCGACTG 408

<210> 70

<211> 503

<212> DNA

<213> 人类参考基因组hg19

<400> 70

CCTTCTCTCC CTTGATATCT GGCAGGGCAT AAAGGCCCAG GCCACTTCCT CTGCCCCTTC 60

CCAGCCCTGC ACCAAAGCTG CATTTCAGGA GACTCTCTCC AGACAGCCCA GTAACTACCC 120

GAGCATGGCC CCTGCATAGC CCTGGAAAAA TAAGAGGCTG ACTGTCTACG AATTATCTTG 180

TGCCAGTTGC CCAGGTGAGA GGGCACTGGG CCAAGGGAGT GGTTTTCATG TTTGACCCAC 240

TACAAGGGGT CATGGGAATC AGGAATGCCA AAGCACCAGA TCAAATCCAA AACTTAAAGT 300

CAAAATAAGC CATTCAGCAT GTTCAGTTTC TTGGAAAAGG AAGTTTCTAC CCCTGATGCC 360

TTTGTAGGCA GATCTGTTCT CACCATTAAT CTTTTTGAAA ATCTTTTAAA GCAGTTTTTA 420

AAAAGAGAGA TGAAAGCATC ACATTATATA ACCAAAGATT ACATTGTACC TGCTAAGATA 480

CCAAAATTCA TAAGGGCAGG GGG 503

<210> 71

<211> 422

<212> DNA

<213> 人类参考基因组hg19

<400> 71

AAACTGAACC TGCACCCCCT CCCTCCTTCA AATGTTTGCC TTTCAATATT TTGTTAGGCA 60

GGCAAGAGTC AAGAGTCATG CCAACTCTAG TAATGTGGCC TCTGTTCAAA CACCTACCAC 120

AGTGTGGCAA AGGGAAAACA GCATGGGCTA AGAGTGGCCT GGATTCAAAT CACAGTCCTT 180

TTATTTACTT TCTATGTGCC CTTGAGTTGT TTACTTTAGC CCCCTGGGCC ATAATTTCTT 240

TCTCTGTAAA ATGAGAATAC TTGCATGAAT ATGAAACACT GAGCAGTTAA TAAATACGTG 300

CTTAATAAAT GTTAGGTTCT TTGTTATCCC TGCCAGTTCA TCACTTTCAG TTCATCCATT 360

GCCAGATTCT CTAACTTGCT GGCCAAGGTA TGTTGATAAT TTCCTATAGC TGCCACTCTT 420

CT 422

<210> 72

<211> 563

<212> DNA

<213> 人类参考基因组hg19

<400> 72

TTTCTTATTC CCCAGTTTTT CTTTATCATA TAATTTAAAT ATTTATTCAT TTTGTATTTA 60

AAGACTACCT ACACATAGAT ATATGATTCC AAAGTCATAC TTTCTCCATC CCCACATTAG 120

CCAAGTGAAT ACAGGGCCAA ATGGGTTCTT GGAATGATAA TAACAAAGCA TTACAAAGTG 180

GGTCCCCTTG GTTCCAGCCT TGTCCAGAGT TTTTGGTTAT ATATTTCTAT TTATTACAAT 240

TTACCTTTTA AATTGTAAAA TAAACCTTTG TGTGGACAGA GCCAATGTTT CAATCTTGAA 300

TGAGTAAAGA AAATACTTTG GAACTGATCC TCATTTTGAA ATTGGTTCTA AATTATTATC 360

CATTTCCAAT GTCTGAAATT CTCTTACTTC CTGCTAAAAC TCTCTTTCTG CCAAAGTTGT 420

TTCGTAATCT GTCTCAATGA CTATAATGTA AAATTAAAGA AGTAACCATG CTTCTCAAGG 480

GGGAATTAAA AGTGTTTATT GAATTTTACT CAGGCTAATT GTTTGGTCAG AAATTCCTAA 540

GGCCACAGCT TTGGGGGGTT CGT 563

<210> 73

<211> 414

<212> DNA

<213> 人类参考基因组hg19

<400> 73

TACTTTGTAA GCTTCAGCCC CTCCTTCTAG TCTGTCAGGA ATGGGAATGT TTTTGAAAAC 60

AGACTCTGAA AGCCAATGAG ATGTGCTCCT CCTGCCCACA GTTGGACCCA GGCTCCATAT 120

TTGATCAGTG AACAGCCACG TCCGCACATG TGCCACAAGG CATTTGTCTG CAAATTCATC 180

CGGAGACCTT GACAGATGCC TGGAGGTCAG AAATCAGCCT CCTCTATGCT GCCATGTGGC 240

CCCAGGAGCC TGAAGGAAAC ACCAAGTACA TCTAGAAGTT GATGGTTGAC CGATGGGAGA 300

GGGGGCAAGA TGCCAGTCAC TCAGTCAGCC AACCTTTCCT GAAGATTGTT GGAGGCTCCA 360

AGTGACATAG GGGATAATGC AGAGAACATT CAGAGACATC ATCTACTGCC TGTG 414

<210> 74

<211> 460

<212> DNA

<213> 人类参考基因组hg19

<400> 74

CGGCCGCCTG AAAACAGAGG CAATGCAGCC AAGCTTTGTC CATTCCCACT GTGGGCCTGC 60

CCCAGGGTGC TCTCACCCCC TGCTGTTTCC TGGCCTCTTA AGTGGCAACC AAGGTGGGCA 120

TATCAGGGCA ATTTAGGACA GGCCTAGCTT CTGCTTCACT AGCTGCCCCT CCCCTAACCC 180

ACTCCAGTTC TGATCTGGGC CTTTCTACCA CCTTAAAAGG ACCCCTTCCC TCAGCCTCTC 240

TAGCCCAGGG AGGGACAGGC TAAAGGGCTG TCTGGGAATT GGCCAGAGCC TCTCAGGATT 300

GTGATGAGAG AAGGGGAAAG AGCATGTGGC ATGTGGCAAC ACAGCACCAG CAGGATGCTT 360

ACCTCGCTGA GGGGTCTTCC AGTCAAAAGC CAGCCAGGTA AGAATAAGCA CAGTGACAGG 420

CCAGTATGGT GTGAACACCA CCAGGTAGAG GTTGACAGCA 460

<210> 75

<211> 446

<212> DNA

<213> 人类参考基因组hg19

<400> 75

TTTAAGTGAA TGCATAGAAT CCAATTTGCC AAGGTTCTAA AGGCTTATGA GGTCCTGAAG 60

GAGCCAGGCC TTGTGATGGA GTAGGTGACA CAGGCCTGGT TGTCCTGTCA GCAGAAGGGA 120

AAGCAGGGGC TGGGCTGAGA GGAGGACACG GAGGGCTCTG CTGAGGTTCC TTCCTGGGTT 180

CCACCAACAG GGACAGGGAG TCACTTGCCT TCCAGTTCTG TGCTGGGATG GCGGGACAGC 240

ACTTGGCTTG CTTGGCCAGC TGCGTCATGA GTTTGATTTG GTTTTTTTTT TTTTGCAGCT 300

GCTTCATATG CTCTGCTCCA GCCCCTCCCC AACAGCTGGT AGCTTATGGT TTCTTCAAGA 360

GGAAAGTAGA CTTTATGCTG TACATTTGAG CTGTAGAGCT AAGATTCGCT TACTGGTGAG 420

CTGTGAAACC TTGTTGCTTT TTCCCA 446

<210> 76

<211> 551

<212> DNA

<213> 人类参考基因组hg19

<400> 76

AGAGAAGATG TAGGCAGTGG CGGCAGGCCC TGCGCCCACA GCTCCTCGCC TGTCCTTTGA 60

CCACAGATCC CATCCTGCAT GACTCAAGGT CCCATAGGCT TGGCCTAGCT CTTATGATAG 120

GGGAACAATA GAGGGGAACC CAGCCTCAAC CCAAGTCAGA AGGTAGTTTT TGCCTTGGGA 180

GGTCTGTCCA TTGAACTAAA GGGAGGCAGT TACAGAGGGG GCTAAGCATG TTGACACCAT 240

GGCTCATGGC AACCTAAGAT GGCAGAGAGA CAAACACAGA AACCAAGGGG ACAGGAGTCT 300

GCACAACAGG AGTCTGCTCC CCGTACTTAG TCATTCTCTG CCTCTGAGGA AAAAAAGGCA 360

TTTGGAAGAT TTTAAAAACG GCAGCACCAA GGATTGGTGC TTGCCGAGGG GGTGAGGGAT 420

ATGCGGTGGT GAGATGGTGC CAACAACCAA TTATTTCATA GGAGGGGAAG AGTGTCTAAG 480

CTCTGTGTTT TATGTAAATG GTCCCCTCAT CGCTTTCATT GTTTATTTCT TACCTTTCAG 540

ATAAGACCTT T 551

<210> 77

<211> 414

<212> DNA

<213> 人类参考基因组hg19

<400> 77

CACCCCAACC CCTTAAAAAA AAGGTCAGAA GGACAAAGCT GGTTTGTTTG GGAAATGGAC 60

TGATCGAAAG AAAACTTGCC AAAGTGGAAA GGTGGCTTTT AGCATTCTGT GTTTCCAAAT 120

AATGAATTTG AACACCAGGT TGGGTTAATT AAAGCTTTTG GTATAATTTA AAATTAAATT 180

TATAAATGCA GTTGTCTTGT TACAAGCCAC CTTACGCAAC CGCGCTGCAG GGGTGAGGAG 240

TGGGGAGAAA CCAGAATGCT TCTGAAACTC CCACCTGTTG CTCTGAGCCC CACGCGCATG 300

CTAATGCGTG GAGTGTATGC GCAGAGTAGC TGTCTGTTTG ACTGCTTCAT CCAGGGAGGG 360

AGAAGGCTTT TCAGCACCAT CTAATGTTTT AAAAGGCACT AGTTTTAAGT GCAC 414

<210> 78

<211> 556

<212> DNA

<213> 人类参考基因组hg19

<400> 78

CAATAGCCCT GATTAACCCT CTCCCTTCTG CATGTTTCCC ATATTACAGA CTTGAGACTG 60

TCCTCATTCC CATATGTAAT AGACATCCAA AGAATTTCAA TTGCTTTGTT GAACTTTTAC 120

TAATGATCTT GTTTTTATTT TCTCTCTTGT TTTTGGTTTT TCACCATTGA TATTGTATTT 180

AGAAGGTTTC AGGTGGGTGA AACCTCCTAT TCCATGCGTA AGGTGCCTCG CTGAAGGGAG 240

CTCGAGGCCT GGATCTAGGG CAGACACACA ACCTCCTCCT CCTCTTCCAG CAAGGAACGC 300

ACCGAAAAGT CACATGATGA GAAATATGGT AACGGGTTTG TAACTGCCAC AGCAAAACAA 360

TTTGCCTCCA TGCCTGAATC TTCTGTCTTG TGGCTTCAGA AACAGCTTAA AATAATTTTA 420

TTTACAAGCA AGTTATGTAA GAGAATGTTT TATACTATAG CCACAATTCT GTCAAAGATA 480

AGTAAAAGTT AATTGATATT AAAAATTATT AGAGATAATT TACTTAGTAA AAGCTTCTAA 540

CTCTTCTTGT TGTTCA 556

<210> 79

<211> 512

<212> DNA

<213> 人类参考基因组hg19

<400> 79

TGCAGTGAGC TGTGACCATG CCACTGCACT CCAGCCTGGG TGACAGAGCA AGACCCTGTC 60

TCAAAAAGTA AAAAATAAAA TAAAATAAAA ATAAATAAGT GACATACTAG TTCCTCGGAT 120

CTTTTACTTT TTTCCAAATG AAGTATGCTG TCAATTTACA TTTTTCATGT TTTTTCAAAA 180

GCACACAATT TACTAGTTAA CTCAATGAAT TACAATACTG TTATTGAATA TAAACATACT 240

GAAGAATTAA AGGGAAAAAA ACACACCTGA CACTTTAACA TGTGCCTTAA CAATCTTGCA 300

TACTAAGGTA CAGAATACTT CAGAAAGTAA CAATTAGCAT AGTCTTATAA GACTAGGAGA 360

ATAAAAGTGC CCTGCAAACA TGGCTTCTAT GTACTTAATA TGGTAAAACA TGTGACAGGG 420

AAGCCTGTAA GGTAAAACTT AAAAAAAAAA TCAAATAAGG CAGATTATAA TTTTTTTTGT 480

TCGCAAAAGA ACAAAGGAGA AAAGGGGAAG AA 512

<210> 80

<211> 627

<212> DNA

<213> 人类参考基因组hg19

<400> 80

GGAGTACTGA ATAAAAAATG TGATTTAAAA ATTTGTACTT AAAATTGAGA TTTAAGTTTA 60

GTGTGTGGCA TCAAATATTG GTTATCCTCA GACTAAGGGT ATATGGCCCA AATCAGTTGT 120

TGCCACAAAT TGTTCATCTT ATCTGATAGT AAATGTACTT TACTCATAAG AAGAAAAATT 180

TGGTTGAACT GGGATGCCTT AACATTTTCT TTAAATGACA TTGGCATTGC AAGATTAAAC 240

ACTGAAAGAA CACTAAAGCC ATGATATGAG TGCACTTTTG ACAAAACTGG AATAAAACAT 300

TTAGGAAACT ATTTAAATAA AAGCATTCTA TATACTTCAT TTATCATTAG TGTTGATTTT 360

ATAGCTATTT TTATAATTTA TCCCAGACTA TTATAAAATA TATAAAACTG AGATATAAAG 420

TATCAGCAAT ATAACTTTGC ACTTTAAATA ATTTTCAGCT ACAGATTTTG CTTTTAGAAA 480

ACAAACTTTG AAAGCAGCTG TTTTGTTTCC TTGTAAAACG TTCTGTAAAT GCATATACTT 540

GGGTCCCTGA TGGACTTAGC TGTTGTGGCC TTCAGACTTT TCCAAAATTT TAACCCTTAC 600

ACAATGGAAC AAGAAAATCT TTATTTT 627

<210> 81

<211> 496

<212> DNA

<213> 人类参考基因组hg19

<400> 81

TATTTGTTTT TGTAACTTTA CATGCTGCTG AATTAGATCC TTGATTCCCT CAGGGTCATT 60

TTTACAGAGT TTTTGAGCTG TTATGTTTGC TTGCAGGGCC CAGTTATATT CCCCCAGCAT 120

AGAAAGAGCA TCACAATAAC GATAATGACC CTTTGGCCAA GTGTTCTTCA GAATAGTGGC 180

TCTCTTTCCA TCACCAAGTG CATTTCTAAA CTGTCCAGTA CGAAGAAAAC AAAGAGCTCG 240

GTTACCATAA AGAAGGTGGT TTTCAGGTCT ATATTCAATG GCTCTGGTGT AATAGATAAT 300

AGCTATATCA AATCTTTCTT TGGAAAACTC TTCATTTCCT TTCATTTTCA TTAGTTCTCC 360

TTGCTCTATA CAATCCATAC AACTTTGGGT TTTAAGTTCT TCAAGCAAAT TGCAGTCTTC 420

CATTACAATT TTAGTTATGT GGTACTTGTA TTCAGTAAAG AAAATACTTA ACATAGGCCA 480

ACAATTGTCA ATTGAT 496

<210> 82

<211> 692

<212> DNA

<213> 人类参考基因组hg19

<400> 82

AAAATGCTAG AACTTGATTT TCTAAGTCCA CATCCCACTG CCAGCAACAG GATGAAGCAT 60

TAGCACTGGC ACCATGCAGT TAAGAGATGT GCTTTATATT CGTGCCAGGA GAGAGAAAAT 120

TCATGTGTGG AAGATAATCC ACAACCCTGA AATTTTACCA GTAATTATTT CAGCACATAT 180

AACTGAAAAT AAAAAATGGC AGAAGGACTA AAGAAGAAAA AGGAATTCTC TTCTTAGGCT 240

ATACTTAAGG CTGTTTATAC AATGCTAAGA TAACTGCAAG ACTTCTCCAA CTTTTAGAGC 300

AGTAGTATTT AAGAATATTG CACACAATTC TGTGTCAAAG ATAACCCTCA GTTTCTAACT 360

TTCAGTCACA GAGACAATAA AGCAGGAGCC CAGTTTCAGA CTTCAGTCAA AAGAACATTA 420

AAACCATTTC AATCACTTTA ATCAAGAAAT GGATTAAGTA CAAAAGTATT TCATAACTTG 480

AGGAATCAAC TCTAAGAACT CAGCTGTGTG TTTTTATATG TAAAGAATGA ATATATAAAT 540

CTTTATTCTT TCCTAAATTT ATTAATTTTA TGACAATTTT ATGGTTGCTA AAAGCAGGCA 600

TAAAAATTTA GAGAGGAAAT CTGTGGAGTT GTTACTATTA TGGAAGGACT TGTTTTCACT 660

GAAAACAATT TGAAATATCT TCTGTACTCA GC 692

<210> 83

<211> 534

<212> DNA

<213> 人类参考基因组hg19

<400> 83

TCTTTATTCA TATGTATAGA ATGCTTAAAA TAGCACTGTA GACAAGATGT TTCCAAAACT 60

TTAAGTGCGC ATATCTTTTC TGTATACAGC TTAAAATCAA AAATGTATGT TAAGAGAATT 120

TTTTCTATTA CTTATGGATC ATGCTTTAAA ATGATTTTTC TTGATATTTA TTTTACTCCA 180

TTTTGTTTTT TTCTCTGGGT GAGGCATCTG GTTACTGGTT ATTTTAAAAA GAATAAAGAC 240

ATTCCTGGAA TCACTCCTTT TGGGTTTTTG TTTGTTTTGT TTCTTTTCTA CATTTTTAAG 300

TATTATTTTA CAAAATAGAA AAAATATAGA TTCATGCCAA ATTATTACCT ATTTTTACAC 360

TAACTTTCTG CAGTCCCTCC ATCTGGTATG AGTAACCAGA TAGAGCACAA AGCATGAGTT 420

CTTGTTCTTC AGTTAAAAGA GCTTCTTTCA CAGTGTTGAT AACAAATGCC TTTTGTAGCC 480

AAAACCAGGC GTCTCAACCT TACGTTTTTA GTTAAAGAAA TGTTTAGCTA AACG 534

<210> 84

<211> 409

<212> DNA

<213> 人类参考基因组hg19

<400> 84

CAGCATCATC AGTTTTCCCT AATGACCTAC AATGCTTTCC AATCAAGATC AGGTGTTTGT 60

GGGTTATTCT TTACCAAGAG CGCCTTCCAA TCTATGTATC AGACAAGGTG GTAAATTTTC 120

TTTGTTTCAC AAAAGCAATA TGATTCCTAT TTGAAATTAA TTCACTTTTG CACAACAAGT 180

GACCCACAAG CCAATTCCAG CGGCACAAGA AAACGAAGAG AGCTGCAACA ACTTCATTAG 240

GACAATGTGT TTTGCTCTGG AATATTTCAT TATCAATATA AAGCCACCCG GTCCCAGCCC 300

CACCCCCAAA CATCCCCTTT GAATATTACT TTGTTACATA CTTAAACTAA AGAACAACAT 360

CTCAATACAC TTCAGTGTCA GCAGATACAA TTTGACTCAT GAAATGACA 409

<210> 85

<211> 778

<212> DNA

<213> 人类参考基因组hg19

<400> 85

GGATATAGAG AAAACTAAAT ATTCCTTCTA CCTCAGTCTC CATTCCTAGA GGCAGCCACC 60

ATGACTAGTT TCTCATCTAA CTTCCCAAAG TCTATGGACC ATGTAAAACC ATCCCACATT 120

TAAAACGCTA GTGTAAAAAA AAATAAGATG AACTTTGTCA TGTCATTGTG TAGTTCTGAT 180

AATCAAGAAG TTGCTGAATA AGTCCTCTGT TTTAGCTATT TCTTCTTAGC CAGATGATTT 240

CCCTACATTA TTTTGTAGTT AAGTGACTCA TCTAGTTGGC AAGTGACAGA ACCAGGATTC 300

CAACACAGGT CTGCACTCAG ATCCCAGGCA TGATTATGCC ATACTGCTAC ACTGTGGCCC 360

GAGGTGCCAT CTCCAAAGTA ATATTTCCCT GGCCTCTGTA ACCAAGAGCA TAGCAATTGG 420

AGCTCCATGA ATTGCTTTAC TTCCCACTTG GAAGTAAAGC AGTGGCTTGG CAAAAGGGTA 480

CAGATTAGGA TATACACAGA AGGTTAGCTC GGAGAAGAGG TGCGAGTTAG GATGTTAGGA 540

TACACCCAGA TTCTGGAAGG TTAGGAGACA AAGTTTGGTA CACATATGAA AATTTTTTCA 600

AAGCAAAACC ATGGCTTCAC ACTTTGCCTG GTTTACACAG AACTCACACT TGATAGACAA 660

ATGCCTCTGA AATTGCTGTC AAACTCAGAA ACACCAGCAG GGGGCACTAG AACTCCAGAG 720

AAGACTACAT TCAAAGACGC TACCAACATA GACCAGCAGA GGCTACTGCA GACAATTC 778

<210> 86

<211> 409

<212> DNA

<213> 人类参考基因组hg19

<400> 86

AATGAAACCA AGGAAGATAA CAATAAAGGG AAAGCAGGAA TGTTCTCTGG ATGAGGACAA 60

ATAAGGTTTG CTTGGAGGGT ATGGCATATG TGAAAGTCTG TGGCTAAGAA GATCAAGACA 120

GTCCATAGAA GGGGAGTTCC AATCTTGCCA TAAAGCAGGA GTCAACAAAC TACTTATGTC 180

AAGAGCCAAA GAGTAAATAA TTTAGGGCTT TGCAGGCCAT ATGGTCCCTG TTGCAACTAC 240

TCAACTCTGC CATCATAGTG CAAAAGCAGC CATAGACAAT ACATAAACAA GTGAGCTTGG 300

CTGTGTTCCA ATAAAACTTT ATTTACAAAA TCAGGCAGCA AGACAGAATT GGCCTAAAAG 360

CTGTAGTCTG CTAACCCCTG CCATAAATTA AATTCCACTC TTCTGAGGC 409

<210> 87

<211> 415

<212> DNA

<213> 人类参考基因组hg19

<400> 87

TATAAAATAT TTTACTTGGT TGTTTTCTAT GGCAACCTTT AACTATGTTT CATAAAGGCC 60

CATCAGAGAA TAACACATTC TAACTCCCTT AAAATCTGGA TTTCAAATCC TATTTCAGGA 120

CCCTTTATAA GTGATTTTTT ATTTTTTTAC CTCCTTTCCC TCTCTCTGAT CCTCACTACC 180

AGCCACTACT CTCATCTCAC CCAAATACTC ATCACAACTA CCCATAAATT ACTCTGTTGA 240

TGCCACTCAC AAGATAGGAA AGCAATTTTC AAGAAAGAAG GAATTAAATG AAAAACTATA 300

AAAGACAGTG GAGTTGAAAT TTAAGACTTT TGAACAGGAG AAATGACAAT ATGGAATAGG 360

GAAGGTTATA TTTAATTGAC TAAGGGCAAA ATGAGTAACA GTAAAGGTTC TTGTA 415

<210> 88

<211> 517

<212> DNA

<213> 人类参考基因组hg19

<400> 88

AATATGTTAT AGACGCCATA GACAGGTGAT GTTTGGTCAC CTATGGTAAC TGCTACCTGA 60

TGAAGAGCAT AATTTCTGCA TATCCATCCT CAATACCATG GTAAATTCTG GGGCAATAGA 120

GAAGCAACAG AACTGCCACA AAGTATACCT CAATATAATT CCTCTAGTTC TGCTTCTAAA 180

ATCTGAGGAC AGTGCTAGTG GGAAAATAAT TTTCAAACTA CCTGGTTAAC CAAAATACAA 240

AAGCAGCTGA CTATGTGTGA TTTCATAATA GCACATTTCT TGACACTTAG TGCTAGAAAT 300

GAAGATTTGG ATTTTCCTAA CAACTTACAT CAAGAATGTA GTGTAGCTCA TTATTGAGAA 360

TTTAGGAAAG CCTGAATCCA TTAATTAAGG AAATAAATGT GACTCACATT TCTTTTACTG 420

TGACACAATA ATGTGATCCT AAAACTGGCT TATCCTTGAG TGTTTACAAC TCAAACAACT 480

TTTTGAATGC AGTAGTTTTT TTTTTTTAAA AACAAAC 517

<210> 89

<211> 481

<212> DNA

<213> 人类参考基因组hg19

<400> 89

GAGCTGGCCT GAGGGGACTC CAGGGTGCCT GGAAAAGACA AGCTGTGAGG AAAAGAGTTG 60

GAAATTAGCG CCTAAAGCCA GCCACCTTCG GCTCGGCCCC CTTCTGGCTG TACTGCTCCG 120

GGTGCGAATA GAAACAGCTG GACAAACAGC TCCGAGCGGA TCCTTCGGGC TCACTTCCTC 180

CTCTTCCTCC TTCTCCTCCC CCTCCTCTTG AGGCCGGGGG CCGCCCCCCT GAGGTGCCAC 240

ACGCGGCCCC AGCGCAGTCC CAAGTTTCCC AAGTGTGAGC GGGGATTGGG GCGGACCTGT 300

GGAGGCAGGA AGGGCGGGCA GCAGGGCAGA GGGAGAGCCA GGGCGCGCCC TTGCTCCCTC 360

CCTCCTTTGC TCCCTCCCTC CCCGGTTTGC AGGCTCTCAG GCTCTCGGGC TCCCCTGGGC 420

TGTGACGGCT GAGCGGTGGC AGGAGCTGAG AGCGAGTGAG CTAGTTAGCG GTCTGCACGC 480

C 481

<210> 90

<211> 406

<212> DNA

<213> 人类参考基因组hg19

<400> 90

TAAACAAACT ATAGAATGAC ATAGTATATT CTGGATAAGA GATTTATTCC TTTTCTTTTC 60

TCTTAGATGA TAAGAAGATA TGTTTTAGGG TTTGTGGCCA GTCCAAAATA AAAAGGGAAA 120

ACTTTCTGGT TTCTTTGTTT TTCTTCTATC TTAATTTCTG GATATACTTC AATAATCTCA 180

ATGCCTAGAT TTTTCTGGTC TTGTTAGTCC ATCCCTTTTT AGTGATGGAG TTGTTGGCCT 240

TTGTCCTAAT GTTATTATTA ACTAATTTGA AAAGACTTAT AAACAAAGTG ACAGTTAATG 300

CTAATGTAGT AGTATTCTTA ACTGCGTGTC TGAGATAGTC CTCTGAATAC AGTTTTACAA 360

TTCCCTCTAC TTCTCTCTTC AATGTGAAAA CTTTGGTGGT GTTTCT 406

<210> 91

<211> 448

<212> DNA

<213> 人类参考基因组hg19

<400> 91

GTGGAAGATT GCAAGTGATT GCTTCCGTTT TCAAGATTGG TCTAGTAGTT AAAGGGGCAA 60

AAGTCCATTC TCATTTGGTC CATTAGTTCC AGCAATTGAA ATTTATGTGA ATTATTTTGA 120

TTGTAGAAGC ACTATAATAT GTGCTGAAAC TAAATTTCTT TAATATTTTC TATTCCTGTC 180

AGCACCTTTT CTAGCAGCTG CCAGTTTGGA GCATTGCCCT CTAAGAGCTT TAAAACTATT 240

TTTTTACATG CCTTATATAC ATTCCACTAA TGACATTCTT ATAATAATAT TAAACACATG 300

ATCTTGGTAC TAACATACTC ACTGTGAACC CAGCCTATTG CAAAAATAAA ATCTTTTTAT 360

AATATTATCT ATGGGATGTC AGCACAATAT AACACTCTGG GAAGAAGTGG AGTTTTTTGG 420

TTATTAGGTT AATTTTCTAG TAAAACAC 448

<210> 92

<211> 452

<212> DNA

<213> 人类参考基因组hg19

<400> 92

AAGTTTCTTA TGTATCACAC ATCCCCCAAA TAAGTGATTT TTTCCCAGTG CTTTGTACTG 60

TCAACTGCAT TATCTTTAAT TATTTAAAGG TAGAATTATT TAATTTTGTG ATTTGTTCTT 120

CCATATGACA TTGAGCAAAT AGATCTGTTT CAAAATATGT TCCCGCTATG TGGATAACTC 180

TTCTTTTTAA AAAGAAAATA GAGAATAGCA AATCTTCATG ATAATCCTCA AAAGAACAAA 240

ATGCTTAACT TTATCTCTTA ATTTCTAAAG GTAAATAACC TAGGTTCAGC TTTTGCTTAA 300

ACATTAAATA TCTTTTCCAT TTTTTAATGT TTGTAAGCTA GATATGCCAG CTTTGTTTCT 360

ACATTGCAAC CAAAAACTGT TTCTTTTCAC TTAATTATAA AACCAGTAAT TCATTTACTC 420

TTGCCCAAAA CTATACACTG TATTTCTGTT AT 452

<210> 93

<211> 404

<212> DNA

<213> 人类参考基因组hg19

<400> 93

GTTATCAAAG ATAAATTCAG AGTTTAAATC TCTTTCCCAG GTTCAGTGCT GTGCAAGGGT 60

TCTAATTCCA AATACTTATG ATTTTATCAC CTTTTCTAAG AGAAAATGTT TGCCTGTTAA 120

CTTTTTACCT TCCTTGCTCT TGGTCTCAGC TTTTCAGTTT GAATAAACAC AGAAAGGCAA 180

TTTTCAGCAT TTCAAAAAAT GTACTTTCCT CTTAGTCATT CAAATAATTA CAGTTATTTT 240

TAGATCTCAA AGTTTCAAAA AAAGCAGCTC AATTTCCCTT TAAATATATT ACTAGATATT 300

TTTTGGTGTT GTATATGTTG TTCTATTCTT ATTTTAGGCA CTGTAATTAT TCACAACATT 360

ACAATGACTC TATATCTAAC CTATGCAACA ATTATAATCT TAAT 404

<210> 94

<211> 476

<212> DNA

<213> 人类参考基因组hg19

<400> 94

GTCCCATTTA GTCTCCAGCA CAGCCCTTAC CACGGGGGAC TGAGGCCTTG TTTCTATACC 60

AGCGGCAAGC CCAGAGCCGA GGGATTTCAC AGCTCGTGGT CAAGACAGAA CCAGCCAGAT 120

TCTGGTCACT GGTGTCCCAT GACTCAAAGT AAACAGCCAA CCAGCCACTC CCTCCAGGAT 180

GCTGCCTGGG GTGGGAGGTG AGAGCACCAC CCAGCCCAAG GGCTAGATTC CATTGAGAGG 240

GTTGGAGATC TATTGCAATG ACAAATCCAA AGTGAAGAGG GTCAAGATAT ATACAGTACT 300

AGGCCAGACC CTGTGTAAGT TCTGCCTGTG AGAGTTGAGA ACTGATGCAT ATCCCAATCA 360

GAAGTGAGCA CAGAAAACTG TGATTTGAAT CATACACTCT GTTTTAGGAA AATGTTGATA 420

ATAGATACCA TTTTAATCTT GAGTGCCCCT TAAATGTGTT CCCTCTCCCT TTCCCT 476

<210> 95

<211> 561

<212> DNA

<213> 人类参考基因组hg19

<400> 95

GCTCACACCC CTCAAATAAA CTTAATTCAT TTTAACATCA CTAGCAAAAA TCACTTAGAA 60

ACTGTACAAA AATAAAAAAG TTAACACATT TAATCCTGCA AGGTTTTTGT AAGGACTGGA 120

AGGCAGGCTT TTGAAGCAGC ATTTGGGCAT GGCTGGGGGC TTCTTTGGTT TGATCTAACA 180

CACATAAGAG ATGGAACCTA TTCCAGATGA CAGTTTCAAA TTTCCTGCAC ATTTGAAGAC 240

AAGATAAGAG GCCAGTATAC AAACTTCCGG TGTGCTGGGC ACTGGGACTG TATGTGCTGG 300

ACTGAAAATC TTACAACTGC TTTAAGCTTT AAGGGTGAGG GGAAGCAAGC CTTGCACTTC 360

CTCCATCAAT TTCACTGACC TCTCGTGTTA GGGGAGACTA CAGAGGGTAG TAGCACATTC 420

TCGTGCAGTC AGAAGGCCAC TTGAGGGGTG GGGGACAATT TGTTCTTTTA GAATCTGGTA 480

CCTGGCTGAC CTTGTTTAAG AACAAGAAAA CCCTTCCAGA AATGGAAGCC TTTTGCTACA 540

TACCAAAGCA AAGTACGTAC T 561

<210> 96

<211> 402

<212> DNA

<213> 人类参考基因组hg19

<400> 96

CACTTGTTTT TATACTGAAA GACTAATCTG CTCCAAAATG CTCCCAAGTA GAAATGACAG 60

GACTCAAAAT CCCTTTCTAA AGCCCAACAG CTAACTTTTT CTGACTAATC TCTAGCTTCA 120

TTGAAACTGG CTACCAAGAT TGCATTTCAG GCTAACAATT GGCTTCTTAG TTAAGGCATC 180

ACAACTGAAA ATGGTTATTT CAACAATGGA TGCTGTGGAT GAAGGAATAC CAACAAACTT 240

CTAAGAACTC TCATCAAAAA CTAAAGCAAT TTGCTTTGCC CCAGTGGCAG GCAGAAGGAA 300

TTTAGCCCAT TATCTCACAA ACTAGGAAAG GATTTTTGAA TTCTGAACTA GCAGTCTGTC 360

ACTTGTCACA GTAACTATAT GTATAAGCTG TATCATTTTG AT 402

<210> 97

<211> 516

<212> DNA

<213> 人类参考基因组hg19

<400> 97

CAGTCCCAAG GCAAAATCAC AGGCTAAGAA GAGGCACATG CCCAATGCCT AGACAGGGAG 60

GAAGGAAAAA GTACAAATAA AGATAATAAG AGGGAGAGAC AGAATTGCAC AGGAGAAAGG 120

ATGGATGTTT GTACTGTGGA AAGAGAGACT GATAACATAG AATATAAACT GAGAACAGAG 180

GAAACTAGAC AGAGAAAGAA AAGTCAAAGA GATACACAAG AGGTAGAGCG GCAAAAAGCC 240

ATTGATTCCC TCAGGTTATT GACCTAGTAA TGAGAAACGC TAATGCCTTC AAGTCTTTGC 300

CTTACTTACA AGGTGACTTC TGTTGTGCCA TCTGACCTCT CCCAACTAAC CTGCCCTTCT 360

GATCAGGAGC AGAAAGATGC CTTAATTACC AATTGGAATT CTATACTCCC CTAGTCTCAG 420

GCATCCAAGG TAAGAAAAAA TCACCTCTGA TTCCAGAAGA TGTTGAAGCC AATAAACCAA 480

GGGATAAAAA ATTAGTCTTG TCAGCTGGGC ATGGTG 516

<210> 98

<211> 403

<212> DNA

<213> 人类参考基因组hg19

<400> 98

ACACACACAC ACACACATGC ACCACCCCCT CCCACCACCA CCACACACAC ACACAGCAAG 60

CTCATTCCAT TTAGAGTGGA GGAACAACTG CAAGCCATTC AGTAGCCAAA CAGCAGCTTG 120

GCTTCGAATG CTGTGCCTTT CAAAATATCT GCACAATTAC AAAGAAATAA GGAAATCTTC 180

ATATCTGCTA AAAGCAAACA CAGAATTGGC ATGCATGACC TTCACTTAAA TTTAGTTGTC 240

TTTGCCATTA TGGGCTATGA TTACAGAAAA AAAAAAGCAG TGTTATAAAC CTGTATCTCA 300

AAAGACTGAA AACTATTTCA AATGATCAGT CCTTAGTAAA GAGAAATCCT TTCTAATGTT 360

AAAGACAAGT GAAAGATTTC TGTGTCTTCA GTATGAAATA TTA 403

<210> 99

<211> 480

<212> DNA

<213> 人类参考基因组hg19

<400> 99

ATCCCCTCTA CTCTTACTTC CCCCAAATTT AAAGAAGTAT GGGAAATGAG AGGCATTTCC 60

CCCACCCCAT TTCTCTCCTC ACACACAGAC TCATATTACT GGTAGGAACT TGAGAACTTT 120

ATTTCCAAGT TGTTCAAACA TTTACCAATC ATATTAATAC AATGATGCTA TTTGCAATTC 180

CTGCTCCTAG GGGAGGGGAG ATAAGAAACC CTCACTCTCT ACAGGTTTGG GTACAAGTGG 240

CAACCTGCTT CCATGGCCGT GTAGAAGCAT GGTGCCCTGG CTTCTCTGAG GAAGCTGGGG 300

TTCATGACAA TGGCAGATGT AAAGTTATTC TTGAAGTCAG ATTGAGGCTG GGAGACAGCC 360

GTAGTAGATG TTCTACTTTG TTCTGCTGTT CTCTAGAAAG AATATTTGGT TTTCCTGTAT 420

AGGAATGAGA TTAATTCCTT TCCAGGTATT TTATAATTCT GGGAAGCAAA ACCCATGCCT 480

<210> 100

<211> 571

<212> DNA

<213> 人类参考基因组hg19

<400> 100

CAGTTTTCCA GCCTACAAAG TGGGATTTAT TATTCCTGCT ACTGGCCTCA CCTTATTGGG 60

ACAGTATGGA GCCCTTCCGG AAATTACCCC CCGAGATGCT GAAATACCTC ACAAGAAGAA 120

TTCGGTAAGG CTATCATTCA AGACTCTAGG CTGGTAATAA TATTCAGGTT TATTCTCCCT 180

TTTGCATCTG TGGGATACCC AGAGTTAGAG AGAGGGGAAA CGTCTGCTAT TTTCTTCAGC 240

AGTTGTGTTT TATGGGAAGG GCTTGGTGTA AATAAATGCG TTGCCGATTT TGAGCACAGC 300

TTGAGTGCAG TTACTTCGAG TGAATGAAAA CTGGAAAGGG CTGGACTCAA AGGTTAGAAG 360

GAAAAGGCGC CAAAGGCTGT CCTTTTGAAA CCCTCTAAGA AATGGCTGTG GCTCCTGAGG 420

ATGAGGGTGG GGTGGACCAG GGAGGACTAG TGACTGGGAT ACAGGAGACC AAGGGGACAG 480

CTGTGCTGAT CGGTGGTTAC CCAGCCATGG TGGTTGCAAA TACCTCAGGG AAACTAACAG 540

CAACCAGAAC TGGAACAGGG GAGCTGGTGG G 571

<210> 101

<211> 413

<212> DNA

<213> 人类参考基因组hg19

<400> 101

GGCAGCCAAA CATCTATCTA GTATATTGCA AATTCTGTTC ACTATCCTCC CTTTCTGTGG 60

AGGACATAGG GAAATAGGAA TCATTCTGGC CCAAAGTTCC TCTGCATCAA ATGAAACACA 120

AGAGGAGACT CTACCAAAGC CAGAATGAGG CAGTTCTCCC TTTGCTCACC CATCCCCAGC 180

CCAGAAGGCA TATTGTTGCA TATTCCCCAG CTCAGAAGCT GACAATCATG CATTCAAATG 240

TATTTTGTCT CATTCAACCT CCTTGAAAGG ACCCTGGTTC CTGATGATAA AAACACAAAA 300

AGGGAACCTT TTGTTTAGTG CTGCTAGAAG CAAGAGGGAG GAGGTAGTTC CCTGATTAAT 360

ATTCTAGATT AATTGATCAT CAAAAAGAAG CAGTCAGACC TTGGCTTTCT TTA 413

<210> 102

<211> 523

<212> DNA

<213> 人类参考基因组hg19

<400> 102

CTGTTTTTCT TGCTTCAGTG TGCATTTTAA GTCAATAGAG CTGAGTATCT AGCATTGAGG 60

TGAGGGAAAT GCTGCCTATA CTCCCAGATG TGTTTAGAAT ATCTCAGAAA CAACACTGTG 120

TTTAGCTCGG CTTTCTCTGC TAAGTATGCC TTTCAAGTGT ACACCACGGA GACAGGACCG 180

CGTTGCAAGG CGGGACAGCA GGTTCAGACC ACAGTTCTCA GTCTGACTTT ACTCTTGCTA 240

GGTCTGTCCT ACTAGCTGTT GCCTGCTACC GCCCATGGCT CTCCATCGGA CTGCATGTGT 300

CCTTTTCTAG TTTGCAAAGA CTAAAATGCA TTCCCAAACC TACTGCTAAT CTGAGGGCCT 360

CAGCATCACT TCCAGATCCT TGCTTGGAGC AGTCTCTCTA TTGACTCTCT CAGATCGCTC 420

CACTGCTCCA TGGGCTATCA AGTAACTAAC TGCATACCTG CCGTTGGCAT CATCAGAACA 480

GTCCGAAGAA ATAGTCTCCA CTCACTAATT ACCTCCTATA TAA 523

<210> 103

<211> 474

<212> DNA

<213> 人类参考基因组hg19

<400> 103

CGGCAAGCAA TAGCTTATTA AATAGAAAAT GTAGCAAAGA AAAGTAACCT ATTTTACATG 60

ATCAACAAAA AAAGGAAAAT GACATCACAT TTTTCACAAG GACACAATTT TAATAGTAAC 120

TTATATTAAG ATGCAGTGTC TGCTAAATTA TAAAAATTGC TTTAAAAATA TATTGACTTA 180

ATTATACTCA TTTCCTTTCC TTTATGTATT GACATTTTTC AAATACTTCA TATTGAAATA 240

ATTTCAAAAC ATGATTATTA CAACATGTGG CAAATATCTT CACATCTGCC TTCATTCAAA 300

TTTTAAGCTA ATGCTTAATG CATTAAACTT TATTGATGAA AATACTACAT TCACATATTT 360

CTTAAAACCA GGGCTAGAAG GGTCCTTAGA AAATAATCAC TTACATGAAA TGCTGACAAA 420

TAATTTACAT ACCATTTCGA CACAGCATTC TGTTCACACC ATGTATAATC TTGA 474

<210> 104

<211> 433

<212> DNA

<213> 人类参考基因组hg19

<400> 104

GTAAGAAATA AAAATCTTTC TCTGCTCAGA ATTTAAAAAT AAATGTCAAT GCCACATTGT 60

TCATATCTCT CTACTTAAGC TATAGTTAAG AGGTTTAAGA AAGCAAAACA TTTTTTTCTC 120

CACAAAAAAT TTAAAATACT GGAGGTCACT GTGGAAGAAC AACATTGCCT TATATTTTTC 180

ATAGTTCTTC TTTAATTGGG AGGATTCACA TTTTACTTTA TTTTTAACTC TAATATGAAT 240

ATACACATCC TAGCTGAAAA ATTCAGTGGC ATTGTATTAA CAAGAAAACA AAATATATAA 300

GAGTAATCAC TTTTTTTTTC TGCAAAGTGC CTATCATGGT GAATCTCACA CCTCCCACAC 360

ACAAAGAAAG CATTAAAAAA AAAGAAAGAA AAAGAAATCA ACTACGATAT TCCACCACAG 420

TGCTCTTGAT GAA 433

<210> 105

<211> 442

<212> DNA

<213> 人类参考基因组hg19

<400> 105

CGGCCCAAGT GGTAAGTTGA AAAATGGCGG AGGGGGGAAG AAGGAGGGGC TTTGCAGGGC 60

AGGAGGCTGA CCTCCCGGCC GGGGGTGGGA GGGACACGCC GGGGCCCAGT GGCGCAGCCC 120

GGGCTGGGAG ACTGACGGAC CGCGCCCGGT GTCTCTTTGA GGCCCTGACG TGGACACACT 180

TCGGGTTTCA CGACTCCGGG TTTCTCCAGG GGATGGGCCG GCCGGTAGAG GCGCGTGAGG 240

GAGACGAAGG GACTTCCGTT TCCTTCACCT AGGCTGGGGC CAAGCCGCAG AGCGGAGTTG 300

GCATTTCCAG ATTGGGGCTC GGGCCGCGCC TCCTCCGGGA CCCTCCCCTT GGACCGAGCC 360

GATCGCCGCG GGGCAGTTCG GGCCGGCTGT CCTGGCGCGG TGGGTACAGC TTGTGTAGGC 420

TTTCCCCTCC CCCGCTTTCC CT 442

<210> 106

<211> 405

<212> DNA

<213> 人类参考基因组hg19

<400> 106

GCTAAAAAGA TCATGATACA ATTATTTTAT TAAGTCATGG TTAATAACAA ATGAATCCAG 60

ACTTGTCTAA CAGATTTTCC ATCAACAAAT ATTGTTATGT GCAAAAGTAT TGCCTATGTT 120

GTTTTACACA CCACTGCATT AACTAGAACT GCTGAGAGGA CTGTATATAT GATTTTAAAC 180

CTAAGTTGAT TTTTTTTCTC ACTCTTGAAA GGAGTACTTC TTTGTGAAAG CAGTTCTTAC 240

AGCTTTGTTT TCAACCAGCT AAAAATGTTT TATATATTAC TCTAACCTGT TGTCCTCCAC 300

ATTCTATTGT CCTAATTGTA CTGTTTTCTG ATTTGTATTT ATGTCTTGAG ACAGTAACTT 360

TTTGAATAAA AATAAACCTA CAGTATGTTG TATGTTTTCT CTTGT 405

<210> 107

<211> 415

<212> DNA

<213> 人类参考基因组hg19

<400> 107

ATAATGAATA CTTTATAAAG GATTAATGTC AATTCTTGCC AAATATAAAT AAAAATAATC 60

CTCAGTTTTT GTGAAAAGCT CCATTTTTAG TGAAATATTA TTTTATAGCT ACTAATTTTA 120

AAATGTCTTG CTTGATTGTA TGGTGGGAAG TTGGCTGGTG TCCCTTGTCT TTGCCAAGTT 180

CTCCACTAGC TATGGTGTCA TAGGCTCTTT TGGGATTTTT GAAGCTGTAT ACTGTGTGCT 240

AAAACAAGCA CTAAACAAAG AGTGAAGGAT TTATGTTTAA TTCTGAAAGC AACCTTCTTG 300

CCTAGTGTTC TGATATTGGA CAGTAAAATC CACAGACCAA CCTGGAGTTG AAAATCTTAT 360

AATTTAAAAT ATGCTCTAAA CATGTTTATC GTATTTGATG CTACAGGATT TGAAA 415

<210> 108

<211> 404

<212> DNA

<213> 人类参考基因组hg19

<400> 108

AAAAAAAAAT GGTTGTTTCA ACTTTCAGGT TAATTCTGAA AATGCAATGA AGCAGAACCC 60

CTGCACTCCT AAAGTGTTCC GACCAATTAG GAGTTTGATA CAAGCACAAG ATTCTATGAT 120

AACTTATTTT GAAAGAGAAT AAACTTCAAA AAAGCACTTT AGCACCAACA ACGTAAAAAC 180

TATATACACT AAGATCACAA TTTGTAAATT AAGTGTTTCC AAACGTAGGT AATCTAGAAC 240

TTGGAATGTA CTTTTCCAAT TGAACAATGC TATAAAACTA TGGTAAGCTC TCCAGAAAAG 300

ATGTAGGAAC ACCTTGCTTA CTAGAAAATT TTCTCTTCGT ATCTGCAATG AAAAATAACT 360

GAAAACAATG CTGTTGTAAT ATTGGTAACG AGGAAAAACA AGGA 404

<210> 109

<211> 465

<212> DNA

<213> 人类参考基因组hg19

<400> 109

CTCACAACAA CCCTGTGAGG TAGGCATTAT TATTAAACCA ATTTTGCAGA TCAGGAAGCT 60

GAGGCACAGA GAGAAGCATT ACACAGTAGA TCAGATAGAT ACTGTTATCC CATTTTTAGA 120

GTAGAGGAAG CCAAAGCACA GAAAAGTGAA GTGACTTGCT CAAGACCACA CAGGGAGGCA 180

GTGTCAGAAA TAGAACTAGA AACCAGTATT ACTGCTTCTA AGTCTAGGGT ACTTTCTGTA 240

GCACCACAGC TTTCCCCAAG CCTATTTAGC TGGATAGAGA GACTAAAGCA AATGTGGCCA 300

ATTCCATCTA GAAACCTCCA GGCCATGGGG TGGGGGAGTT CGGGCTGGGA CATGTCTGGC 360

ATTTTACATT TTGGGGAAAT TTCTTCTATA TTTAGAGATT GGTGCTGCCT TACTAGCTCT 420

ACTGATAGGG AACCAAGGTG ATTTATAAAG CCATTTCTAA AATAT 465

<210> 110

<211> 562

<212> DNA

<213> 人类参考基因组hg19

<400> 110

CAAAACACAT CACAAACTGC ACTTGAAGAA AAGGGATATT CCATCCATAC AGGTAAAATG 60

TGATCTTTAG TTTCTTTTTA CAACACTGCC ACACGTAAAC AAAGTCTCAA AGTATTAACC 120

AATAATTTTA AAGGAGAAAG ATTTTACAAA TAGGATGAAG CACTGGTACG AGGTAATATA 180

CAGAAGTAAC CATTTGTTTA AGGCTCAATT TTTTCTCCAT TATAACTTTC TTTTAAAAGG 240

CATTGAGTAG GTAATACTGA GTTTGAGTAT TTAATAAATA CAAGTCGAGA AACTGATTAA 300

AGAAATCAAT TAAAATATTA AAAATTAACC CTTGTATATT AGCCATCAAT AAGAACTTAG 360

AAAGCTATAA AAGGACTGAT TGATAAAGAA TGGATTTTAA ACGTATGGTA AACGTGCTAA 420

GCATTCCTGT TTAAGGTCGA TGGATCTTGA AGGCCAAAGA CCTTATGCAC TTAAATAGAT 480

GTATGGCAAC ATGCTGTAAT AGAGACAGGT TTACCAAGGC TCAGTTCTGC AACCCAGGTT 540

GTAAAGTTCT CCAAAGCAGC AT 562

<210> 111

<211> 731

<212> DNA

<213> 人类参考基因组hg19

<400> 111

GCCATTTTCC ACCCAAATTA TGTGCCTCCA TTTTTCACAT TATTCCAAAT TGTTGTTATA 60

TGAATGCACA AAGTTAGTCC TTTAAAAAAG AATATATTTA GGAAAATCCT TCAAAAGTTT 120

TTTAATTTAA ATCATTGTAA TTTGGGAGCA TGGGGACAAA TGGCTCATTT TCTGTTAAAG 180

CAGCAACAAT AATATTAAAA TATTATTAAT ATTATAATAT TAAAATAATA TTAAAATATT 240

AATAAATAAG TTTATTTTGA AAAGGGCATT CATTCCCATA ATCCAGTGAT ATGATGGTCA 300

TATCATTCTC TCAACTGCTA GACACAAAAG ACATAGCAAC AAAGTAATTT GTTTCCATCA 360

CTAACAAATA GCATCTCTAC ACAGAAATAA AGCTCTGGAA CCATGCAGTT TTATGACAGA 420

TAAATCTTTA GGTTGTGTGT TTTCAGAGAA AAAAGCACTG CTTAATAGTT AGGTTACTTT 480

TAGGTCTTGT TACAGAGGTA TTTTTTAAAA AACTAATATG ATGTAGATGC CTAGCAAGGA 540

TTTTGCAATA TCTGCAAAGA GCTGCGACTT ATTTCATAGT CATACATTTT TTTTACATAT 600

ACCATAATTG TGGATGGATT CTATTTAAAG ATAAAATTTC TCTTCAATAA TCCAGCTTTT 660

GAGTATTAGT GATTCTCTTA CAGGCAAGAA CAAGTAGAAG AGCTGGAAAC TGCACAAATT 720

AGTCAAACTA A 731

<210> 112

<211> 539

<212> DNA

<213> 人类参考基因组hg19

<400> 112

ATGATGAATT TCAAAAAGGC ATACACTACT TTCTTCTATA GCAATGTTAA GATTTCAGAA 60

ATAGAAATTA ACTGGTTCAA AGAGTCCATA GGTAAAGGTC AGGACAACTC TTGATCTCTA 120

ATTCCACGCA ACATTGTCAA CAGCTGACAA TGACTCAATA CAAGCAAGGC TGTTTAGAAA 180

GCACTGTTGA TCAGGATTTG GATGGATAAT TAAGATCAAC AGAGTATCAA TTCCCAGAAA 240

GCTAATTTTG CTCTCTTATA TTCTGAGCCA AATGGGTCTG CTTTGGAAGA GAGCATCAAA 300

TGTTCTGAAG CAAAAACAAT GTGAAAAGGA GGAACAATGG GAAGCAGGAG ATATTTCTGG 360

GTCCCACAAT GGCTAAGGTA GCCTTGGGCA AGTCATATGC CCCTGGATTC AGTTCCATCA 420

ACTATAAAAA GGATTTTGCT AATTCCATTG TTCTGTGATT CAAACACTTC TAGCCAGCTT 480

AAGGTATCCT CAATCAGATT TGCTTTTTAC TTGTCATTTT CATGAAGGAG AAAAACCAT 539

<210> 113

<211> 409

<212> DNA

<213> 人类参考基因组hg19

<400> 113

GTCTTTGGCC TGGGACAACA GATATGGCCA TGGCCTTTGC CACTTCACCC ACGTGGCTAA 60

AGGTCACCAC TAAGATGTAG TATTCTCAGC TCTACCTACT CCCACCCCAC CCCATCCCCC 120

AAGAAAAACA ACACATACAA AAATCTGGAC ACCTAGTTCT CCCCTAAGTG GGCTCCTTGG 180

CTGATATCTT GGATCGTAGC ACATTGCTGT GAACCATGGC AAGTCCTTTG TTTTACTGAT 240

AAGAGGGGGC TAGGTAAGAA AAAGACTCAA ATGAGACACC TTATACTCTC TTAAAACAAA 300

AACTGGGATC CCAAAACAAA TGGAGATACA CATGCACAGA CAAAAACTTT GCCCGAGTGT 360

TGACAGCTAT TCCCTGAGCC CAGGCTGTAC CCCAGTTCTG GCTAGCTCT 409

<210> 114

<211> 481

<212> DNA

<213> 人类参考基因组hg19

<400> 114

CATAAGTGCT AGAGGCATAA CACATGTACA AAGATGGTTA AAAATGCAAA TGAAATATAA 60

CAACACATAA ATCTCTATGG CCAGGGCTGA CATCATTCAG CCTTTAAATG GCTACTCATT 120

GAGTAAAGAC ACTATGCTAG CTAATTTAAA AATTAATTTA GATCTTGTAA GCACTTAAAA 180

AACCAGAATG CATTAATATG AATCTTGCAA ACAATAGAGG TTCCATTGTG ATCACTTACA 240

CTCTATTTCC TGGTATAAAT TAGAGTAGGA ATGGAGAGGA ATATTACAAA TCCACATCTT 300

TAAAAAAATC AACAATCACA ACTCATTTGG GTAAAAGGAC AATTTCTGCT TTTGTCAGTT 360

CCCTTTAGAA AGTTAACCTG TTGGTTATCA GAGAAGGGGG ACACTGAACA CACAGAAAAC 420

TAACCTTCTT CTGGCAGCTG GGGATAATTT GTCAGTTTCC TTTGAAATGT GGCTTTGTGC 480

T 481

<210> 115

<211> 415

<212> DNA

<213> 人类参考基因组hg19

<400> 115

TTGTCACAAG AAATGTTAGT GATCAAAAGC TTTTACTGTT GCAATAAGAG AGATATCTTT 60

TTATTTTACA GATATTTGTG TCGTCACTGT CTTCTCAAAT CATGTGTAAG AGTTTGGAGA 120

TGTCATGGCG GCACAAAAGA GAGCTGTTTT CTCTATTTTA TTCCTTTAAC TGCCATGGTT 180

ATTTTTATAA AACACATCTA TGTTTCTCTT ATTAAAAGTA ACCTTAATTT CATTGGAATT 240

TAAGAATAAA TAGATCTGGA TTCATATATT ACATCAACTT CCCTTTTTAA CTCTAGAAAT 300

TCTCAGTATG GGGTTTCCCT CTGGAAAAAG AAAATCTGAA GACATTACAG TTGCCTATTG 360

CCTCTTAAAT GTGTCCTAGA CACAGCATGA AGTTGGGGCA CTGGTGGTGA GAGGC 415

<210> 116

<211> 882

<212> DNA

<213> 人类参考基因组hg19

<400> 116

CTGGGAGGAG AAATTGGGGT GTGTTACTGT TTACCATGGC AGTAATGGGG CAAACAATAA 60

AATGCAATGT GAAATGATTT GATGATTTGG GAAATAAGAT TGAACGCAAT TTACTTGTTT 120

GAATTTGCTG TTACTTGCTC TTCTTATCCC ACTCTCTTCT GATTTTTTTT TACTTTCTGC 180

TCCTTACTTC TCTGCTATTT TCATTGCCAC TTTTTAATGT TCCATGTTTG GTTTTATGTG 240

CAGCACCTTG ACTTCTAAGA AATGAATCAT GTCCCTTTGC CCCTTATAAC TGAACTTTGA 300

GTATTTTAAG ATTTATTCTA TTCTTACTGT TGTGTATTTT GTTTCCTTAT AGCCATTAAA 360

GAAAGCACTA AGGATGATGG GAGCTCCAAA TCTGATATCA GATAATTTAG ATTGTGGACT 420

TAGTTACAGT GTTATCTCTT ACCTTAAAAA ACTCAGCCAA CAGGTAGTAT TGGTAAAAAC 480

AAACAAACAA AAATCCTTTG CCCTCAGAAG TGCATTTCCT TATTCTTTAG TGTAATTGTA 540

ATTTTTCAAA TTAAATGTGT ATATATCTCT ACACTTTATG GATTAGTAAT AATGTGATTC 600

TCTATGGCTT CTAGCTTCAC CATTAAGCTG CAGTTAAGGG TCTGTCAGTA TCATTTGATG 660

CTGTGCCATT TCTCCTTTTG CCTGCCAGTT TGTCCTACCC GCAAGCTGGT TGATATGGGG 720

CAGAGGTTTA ATAGACTTCT CTCATGGGTC ACATTTTGTC TATCTTCAAC CTAGTTCCTC 780

CTCAGATCAC TCTGGGCTAC AGCATCCCTC CTGTTTAGAT CAGCACACTG AGGCGTGGTG 840

TGATTAAATG ACTTGTCTGA GATTAGTTTT CAGGCATGTG AA 882

<210> 117

<211> 410

<212> DNA

<213> 人类参考基因组hg19

<400> 117

TAGTGATAAT AAACATAGAC TTAATTCCAA TAATTAGGGA AAATTGATAA ATATCTGTCA 60

CCAAACCACA AGAAATCCAA AATCATTTTA GGTTTACCAA ACATTGGTGG AATTCCATCT 120

TTCTGAGAAA AAGGGAAGAT CATAGCTAAT TTATAATAGC TCAAATTACT AATTTAATAA 180

CTGGGTCACC AGTGTTTCTT GAGCCATTTC AGATGTATGT AAAACACAAA ATATGCCAAA 240

TATATATTGC TATAATACAC TCAAGCAGTA TTAATCAATA TGGTATCACA ATGCCTATTA 300

AGAGGCTTTT TACAAATTAC TTACTTAGTA ATATCTGTTA AATTAAGCAT TATCTTCTAA 360

GACCTTTTTT GGATAGTCAA ATATAAGAGA TAAATAGTTT AATTTTTTCA 410

<210> 118

<211> 442

<212> DNA

<213> 人类参考基因组hg19

<400> 118

CAGTAGCCCT GAACAAAATT TACTCATGCC CCGAAAAGAA TTTCTGGGCT TTGTATTGTT 60

TCACACAAGT TAAAACAATG GGCACAAAAG CTGTGGTTTC AACAAAAGCA TATTAAATCA 120

TAATGTTGTG CTTTACTTGA CCTTAGCCAT TTTGCAGCCG TAATTTTGAC TTAATTCATT 180

AATAAACTAA ATAATCCAAG GCACACCGAT TGCATTTGGT TACAAAGTAG AGAAGAAATA 240

ATTTTCAAGT CCAAAAGTAT TCTGAGATGA GAATCTTTCA AGCACAATAT CTGACACATT 300

AAATACATGA TTTTAAAAAG ACAGCGTACC ATAATTAAAA GCTTTATTAA ATGAAAGAAA 360

AGAAGTATGT GCTGTGGTTT CTTTGCGTGT CCATTAACCT GAAAACAACA TCTGCATCAT 420

TTGAGCTCAA TGTCTTTTGC GC 442

<210> 119

<211> 448

<212> DNA

<213> 人类参考基因组hg19

<400> 119

CCTGTGCCTC TCACCTGTCC CAGCAGCTGT GTCTGCACCT CTCAGAGCTC AGACAATGGT 60

CTGAATGTAA ACTGCCAAGA AAGGAAGTTC ACTAATATCT CTGACCTGCA GCCCAAACCG 120

ACCAGTCCAA AGAAACTCTA CCTAACAGGG AACTATCTTC AAACTGTCTA TAAGAATGAC 180

CTCTTAGAAT ACAGTTCTTT GGACTTACTG CACTTAGGAA ACAACAGGAT TGCAGTCATT 240

CAGGAAGGTG CCTTTACAAA CCTGACCAGT TTACGCAGAC TTTATCTGAA TGGCAATTAC 300

CTTGAAGTGC TGTACCCTTC TATGTTTGAT GGACTGCAGA GCTTGCAATA TCTCTATTTA 360

GAGTATAATG TCATTAAGGA AATTAAGCCT CTGACCTTTG ATGCTTTGAT TAACCTACAG 420

CTACTGTTTC TGAACAACAA CCTTCTTC 448

<210> 120

<211> 470

<212> DNA

<213> 人类参考基因组hg19

<400> 120

AAGTGCATCA CAGGTTCAGG GAACAACACA GGTTGAGTGT GGCTTGTAGT AAAAATGGTT 60

GTGAAGAGTT GACATATTTT TAAGCCCTGG GTAAATTGAA CAACAGCTTA CACTTGGAGG 120

GGTATAATCA TTCTAATCAA TGTGTCCCCT TTTACTATAA TACATTGGAG TTGCAGCTAA 180

TGCTCTGCTC CCATTCAGCC TATGATGAGA TTCTCTTTCA GCCCTATTGG GTTCTTGGCC 240

TCATGTGACT ACTCCAAAGA CCCTAGTCCA AAAGGTCTTT CCTGTTTGCT ATGGCCTTGA 300

GGAATGTGGC CCTAGATCCA CCGCTTTAAA GCTGGAGTTC CACCAGCAGC AACATCCTCT 360

CATTCTGGGG CACCTGCCTG GGGCAGGTCA TCCTGCCTCT GCCAACTCAG TGCTATTAGT 420

TAACTCTCAC CTGCCATATT CCAGCTGGAA TCATCTCCCC TTCTCCACCC 470

<210> 121

<211> 485

<212> DNA

<213> 人类参考基因组hg19

<400> 121

CTAAAGTACT GAGCAGTGAT ATTCTTTGTT AATTTGGACC ATTTTCCTGC ATTGGGTGAT 60

CATTCACCAG TACATTCTCA GTTTTTCTTA ATATATAGCA TTTATGGTAA TCATATTAGA 120

CTTCTGTTTT CAATCTCGTA TAGAAGTCTT CATGAAATGC TATGTCATTT CATGTCCTGT 180

GTCAGTTTAT GTTTTGGTCC ACTTTTCCAG TATTTTAGTG GACCCTGAAA TGTGTGTGAT 240

GTGACATTTG TCATTTTCAT TAGCAAAAAA AGTTGTATGA TCTGTGCCTT TTTTATATCT 300

TGGCAGGTAG GAATATTATA TTTGGATGCA GAGTTCAGGG AAGATAAGTT GGAAACACTA 360

AATGTTAAAG ATGTAGCAAA CCCTGTCAAA CATTAGTACT TTATAGAAGA ATGCATGCTT 420

TCCATATTTT TTTCCTTACA TAAACATCAG GTTAGGCAGT ATAAAGAATA GGACTTGTTT 480

TTGTT 485

<210> 122

<211> 515

<212> DNA

<213> 人类参考基因组hg19

<400> 122

CGTGGTAAAA TATTCATGTA TTTGTGCTGC ATTTCTAATT TTTCCGTAAC TGACACATCA 60

GTTTTATAAT TAGGAAAAAA ATACCTTTTT AAAGTAAAGC GAACACAAGA TTCTTTAGCA 120

ATGTTCATTC CATCCCACAA TAGAGTCTAG AGAGTCACAA AAACCTCAGC CTCCTTCGGG 180

AGGGGGGGAG CTTGGTAGTG AAAAATGGTC ATGAATGAAT GGGTGAAGAG AGGGATGGGA 240

CAACCTAGTA GGAGGGAGGT AGGGATAGGC AAGGGAAAGG TGGGGACCAG TAGTCATACT 300

GGTCAGCCAA GGAAAGGGGC ATTGTGGAGT CAGGGAAGAC TCTGACTGCT CAACAGAGGT 360

CTGTCTAGAC CCAGTAGTAG GCACTGACGG TGTTATCAAA GGACAGGATC AAAGAGAGAT 420

TTTAGGAAGA CACGTGGATT ATTTTAGGGA CAGGGGAGGA AAGAGGAGGG GTGGGTAAAC 480

TACTTGGAAA GAAAGGGAGA AGGACTGAGA AGATG 515

<210> 123

<211> 517

<212> DNA

<213> 人类参考基因组hg19

<400> 123

CTGTAAATAT TCCATCCCTT TTGAGATTAT ATACACTAAG CTTTTTACTA CCACTGGCCT 60

TTCTGGATAC TTTCATATTT AGAGAATATA GAACTACATT CTGGGAGATT GACAATGACC 120

TAATATTACA CTAATGAAAA GTCTTCACAG TCCTCAAAAT AATTTAGAAT TTAATGTTTT 180

CTTTAATAAG CAATTAAAAT GGAATATTTT CTGCCTCCTG AATAAATACA TGTCTGTAAC 240

CAACCATCCC TAAAGAAGGA TACTAATATA TTTTGAGTGA TTCAATCCAC CCATGGATAT 300

AGTCACATCT TTAAATGTTT TCCAGTGTGA ACAACAGTCT TTTAATAGAT GGCCATTGAG 360

TTCAAGGGTC ATATTATTTG CTAACAAATT ATTATTTGGG CCAGAAAGTA TCTGAAAAAA 420

GTTTAACCAA ATTTCCTACA CATCTCATAT CTCTAGTTTA TTAAGCATTA TTTATTATTT 480

GGTGTAAAAA TTCTACATTA ATTACTTCAT ACATATT 517

<210> 124

<211> 442

<212> DNA

<213> 人类参考基因组hg19

<400> 124

CTGCGACCCC CGCGCGCAGC CACCTGCCAA GACCGCGGCC ACCCACGCGG CCGCAGACGC 60

AGCCCAGCCC TCGGCGCCGC GGAGCAGGGG GACCTGGCAG CCTGGGCCGC CCGCGTCCCG 120

AGCTGCGTGG ACCGAGCGCG TGCGGGCAGG GGGCGCGCCA GGCGTGACAG GTGTGCTGCG 180

GACGCGCAAG GCTGCGGCGG CCGCGGGCCG GATCCGGTGC GCCCCCGCCC CGCGCGTCCC 240

CGCGCCCCGG AGCAGGTGCA GACCTGGAGC GGGTGCCGCA GCGTCGTGCC GCGCAGTGGC 300

CGCAGCGCCA AGCCCCCCGC CCGCGCCCCG CCGGCCCCGC CCCCTCCGCG CACGCCCCCG 360

CCAGCCGCCC AAGCACGCAG TGGCCCAGCG CGGCCGCGGC GCCGCAGGGC ACCTTGTAAG 420

GCAATCGCCG GGATCCGGCT CG 442

<210> 125

<211> 458

<212> DNA

<213> 人类参考基因组hg19

<400> 125

CGGCTTGCTG GCTTGGAGTG GGACTCCTGG GCTCCACTGC TTTGGGTGGC TTCTGGCTGA 60

TCTGGGCAGG GGTCATCTGT TCAGCTCTCC CCTCTCATCT CAGTCACCAT CCCCCTCCCT 120

CCGAATGCTT TTGTTTGTAA AGAAAAAGTG TCTAGAAATA TTTGTCTCTG GAACAATTAC 180

TTTAAACATA GTTACAATAC AGACTTCAGT TCAAACACAG AAGAGATTTA CTTAGCAAAA 240

TTCCTTTCAC CCACCAAAAA TTACACAAAT ATAAGCCTCA ACACCACAGT TAAGAGGACC 300

AGTAGAGAGA ACCTCATGTT TGGAACACAA AAGGAGAAAT AAAAACCAAA CCAAACCCAA 360

ACAGAAAAAC CCCAGAAAGA CAAGTAAAGG GCAAAGAAGG AAGGGGAAGG GGAGCAAACA 420

CAGCACACGT TACAGTGTCC AGATACACGG GAGCCCAG 458

<210> 126

<211> 420

<212> DNA

<213> 人类参考基因组hg19

<400> 126

GAAAAGAAAG GATGCTGAGG GCTGGCCTGG GCCACTGCAC AGCCAGGAAC AAAGCAGGGG 60

TGAAGTAAGT CAGGCTGGGG GTCTAGCTGC ATGGATGAGG CCAACCTGAG CAAAGGCAGT 120

GTGGCAGGGG GTAGTGTGGC AGGGGGTGCA GCCTGTCTCC CGATTTTGAT GGGGGTTGGT 180

TGGGAGGACT GGAGCAGGAT GGCTTCTATT ATGGGTTGAA TTCTGTCCCC TCAAGGTATG 240

CTGAAGTTCT AATCTGTGGT ACTTCAGAAT GTGATGTTTG CAAATAGGGC CTTTGCAGTT 300

CAGATGGGGT CATACTGGAG TAGGTTGGGT CCTTAATGCA ACATGACTGA TGTCCTTATA 360

AGAACAGAAG TGACAAAGAC ACACAGAGGG AAGACAGCCA TGGTACAGTG GAGGAAGAGA 420

<210> 127

<211> 575

<212> DNA

<213> 人类参考基因组hg19

<400> 127

CGGCTTCTTT GAAAATCAAA ATGACTTCTT GTATGGTCTG AAAAAAGAAG ACTTTGGCAT 60

TCACTTACCT GTGGGGTGAT TGGAAACCCT GAAATCCTGT AGCAAAGTCT ACAACTGCCC 120

CAACTGCACT GACTATCATG GGCCTGACTG CCAATTTGAT CTATCCTCAT AAAGAAGACA 180

CAATCTCAGT CAGAATGCAG GACCAGTATC TGCTTAGTTT CCAGCTGTAG GTGCTCAGAA 240

GGATCAAGAA TGGACACTAA ATAACACTTC ATGCCCAACT GACACCTTCA TTCTGGGTCT 300

CCTGGACCCC AGGACCTGTA AAGGAAGGGG TGACATGACG CCTTCATTAT AAAGTGGGAG 360

TGTTTGTACT CTCAGTACCT AGTCACTTCT AAAGCAGAAG GGAGCAATTG GCTGGGAAAC 420

CTAAGAATGG AATTCATAGG TTTTTTCCTG GTCATTGTGT CTGCTAGCTC ACAGGGAAAC 480

ACACTGTATA GGTGACCATG AGAATGGCCT TCAGACTAAC CATCAGTAGG TATTTCTAAT 540

TGTAACTACT GATGGGAGAG TTCCAGTTGA ACATC 575

<210> 128

<211> 422

<212> DNA

<213> 人类参考基因组hg19

<400> 128

GTGCATTGAC TTTAATACAG GGGTTCCTCC CGTGGGCTCC TGAAGAGCTG ATGCTAGAAA 60

GTGATGCACA CCAGGAAATC CCTCCATCTG CCCAGGACAC ATTTAATTTT TAAGGGGCAA 120

AGCCTAACAT AGAAAATTCC TATTATCATT TTCCCTAAAT GAAGTTACAT CTCTCAAACT 180

ACCAAATCTA GGAATATTGA AACTTAGAAA TGAAGATAGC GGAAAATATT TTAAAAACAG 240

ATCTACAGAC TATGGTCAGG ATTTCTTGGA AATATATTTA AGGTTTCCTT TTCATGACTT 300

GGAAAGAAGA GTACTTTGGT TTAGTTTCAG CTCATGTTGT TAAAAGTTGG ACTATTTTCT 360

ATTACTCATA TAAATTGTCT AATCAGTAAA ATATGCTCCA GATATTGTAG CTTGAAACAC 420

AA 422

<210> 129

<211> 543

<212> DNA

<213> 人类参考基因组hg19

<400> 129

TTAGGGATTC TTGAACCCCA TCTATAATTC TCAGTTTAAG AATGCTAGTT TTGGAGATAA 60

GAATGTGCCC CTCATAATGA CTAAATAACA TAATTATATC TATGTGTAAG GAAGCAGAAA 120

CAGACTTTAC TGTAGTAGTT ATTGTATTCT CTCCATTTTG CAGATTGTCC AAATGATTTG 180

CCTTTTGACT CCAAGATTGT ATTGATCTGA TCCTGAAACA TGCTTTGTTC CATGCTTGAT 240

CAGGATAATA AACAACTGAG AGTTTTATTT TAAACGTATG AGGCTTAACC TGAAATGTTA 300

ACATCATAAA TATCTTTTTC AAAGTTTCAT CACATAGTTT TTCTACAACA GAGGAAGTGG 360

TGACTCTGAG AGGCCTAACT TTTCAGGGAA GAATGCTTTC ATGCAGGTTT CTCCTCACTT 420

CTTTTTGCCT AGTTATATTG GAAGGAAGGA GTAATCTGGG AGCAGCTGCA GAAAATAGGT 480

AAGAGTTAAG TTAAATTGGA TGCACCCTCC TGGCCCCCCA CCAAAGAAAT GCAGGACTGA 540

TGA 543

<210> 130

<211> 599

<212> DNA

<213> 人类参考基因组hg19

<400> 130

TTTTGCCCCC TTGTGAAAAA TCAGTTTGTT GTAGTTGTCC ACGTCCGTTT CTGTACTTTT 60

TATTCTGTTC TGTTGGTCTG TGTGTCTATC TCTTCTTCAG TATGACACAC TGTCTTGACT 120

ACTGTAGCAT TATAGTAAAT CTTAAATCAG GTAGTGTGAT TTCCCCAACT CTGTTCTTTT 180

TCAGATTCAT TTTGGTGATT CCAGTTCCTT TGCCTTTCCA TATAAATCTT AGAACCGGCT 240

TATTTATGTA TCTATAAGAA ATCCTACTGG GATTTGTGAT TTGGGATTGC AGTAAATCTA 300

TGGATAATTT GGAGAGAACT GGGCATCATT TCTGTGTTGA GTATTCCATT CCATGTACAT 360

GATGTGTCTC TCCATTTATT TAGGTTGTCT TTGAGTTCTT TCTTCAGCAT TTTGTAGTTC 420

TCAGTATACA GATCCTGTAT GTTTTATTTG ATTTGTACCT AATATTTAAT TATTTTTTGC 480

ACCCATTGTT GTAAATCATT TAAACATTTT TCATTTCCAG TTCAAATTGC TAGCATATAG 540

AAATTCAGTT GGTTTTGTGT GAATTTGTGT CCTGTGACCC TGCTAAACTC ACTTTTTTA 599

<210> 131

<211> 458

<212> DNA

<213> 人类参考基因组hg19

<400> 131

AAAGACTTTA AAGCCCCTCT ACGTGGAATT TTCTTCTGAG ACAAGCAGTA TATGCCCTTA 60

CAATTGCTGG AAAATAATTA CACTAAAAAT ACTCTTCCCA AACATAGGAT GAATCAACTG 120

TATTTTTATA ATATCCATTT CATTAGGCTT GGAAGATATA AATAGCTTTA CATGGAAAAA 180

AAACCTTGAA TTCAATCAAC TCTTTTTGAA TACTGTAAAC CAACGTTAGG CTAGAGGAGC 240

CGACGGCGCA GCCTGGCTCT ATCATTCGCA GAAGAAACCC TTGATAAATG ATTAAACTCC 300

TTGAGCTTTT TTTATTACTC ATATATAAAA TGGGAATCAT ACCTACCTCA AAGCATTGAC 360

AGGAGGATTA AATGTGATAA AGTATATAAA GTACATACAA TAGTGCCTGG AAAGGACTCC 420

AATACATGGT AGCTATTATT CCCAAGACTT TTTTTTTT 458

<210> 132

<211> 519

<212> DNA

<213> 人类参考基因组hg19

<400> 132

AGACTGTTTA CTTCCAGATT GCAGGTGCCA AGGCATTGAA ACCCCAGGCA TGGTCAAAGG 60

AAAAAGGGGG TATGGCATTT GGGTTATAGT GTCTCTTTCC TAGTTATAGG GTAATTTGCA 120

TGGGACAATT TGTTTCATAC AGCTGGTAAT TCTATCACAA GGGTGTTCAT TTTCTGAAAT 180

GTGCTAATAA CTGTGTCGAT TGCCTTCCTT TCCATAGTCA CATCATTTTT ACTTGAACAC 240

CAGACCTTTT GGTCTGTGTT CCTCATTTTA CAGAAAGCTG TTAAAAGCTA ATTGGTACCT 300

TTTAACCAAA CCCAGCAAAC ACCTTTGGTG CAGGGTATTC TCACGGAATA AGTAGAGCTC 360

ATAATCTTTG TTTAGTTATG CTAATTGTCC CCATTGTGAA ACTTTTTTCC CCTTTATGTA 420

TTTCTTTATG TTCATGGCCT ATAAGTGAGC TCAAATACCA AGGAACAGTT GTCCTGTCTG 480

TAGGTATGTT TTCCTGGGAC TTAGCTTCCT AAACCCCAG 519

<210> 133

<211> 553

<212> DNA

<213> 人类参考基因组hg19

<400> 133

CGTATAGTAA TGTAACATTT TAACTTTTGT AGAAAGTTTT GTAATTATCT AAGGACTGTT 60

TACCTTATCC TTTTATGGAC AACAAGAAGA CCTTTTGGTC AGCCACAGTT TTTATTTTCC 120

TTTTCATTTC TATGAATAAA AGATTCAGTT GACTTTGTTT CTTATATTGT TTTTTAAAAT 180

TATGTTTTAT TTAATGAGTG CTTCTTCATT TAAAAATAAT ATAATCTGGT CACAAAGGCT 240

ACATTCTCAT CTCTGACCAT GAGGTGGTCA TAGTTCTAGG CGTCAAATGC TGTTCTATGA 300

CCAATTGATC TTGAGCTCTT CCTAGAGCTG ATTTTAAAAA TCATTCTTTA AGAATTTGCC 360

TCTCTGATAT GCTCACTCTC TGTATTTATT ATTTATATCA GAAATAAACT CATGTATATA 420

TTAAACTAAC AAAAATGTGA AATTATTTTA GCGATTTATA TGGAAATGTT TCTAAGGAGC 480

AGGGTGAGAT TGTACCTCTA CTTATGACAT TTATAACTGC AGACATCTGT TTAGCTTATA 540

TGTATGCATT CCA 553

<210> 134

<211> 540

<212> DNA

<213> 人类参考基因组hg19

<400> 134

TAGTGGACTG AGTCAGACCT GGAGCCAGTC TCTTCTCTCA AGAGGTGTGA CGCAGAAAAT 60

TCTAGATGCT TAAGTGCAGC TCTTGAAATC GTTTTCCTTC TTCCTCGTGA TCTAACATTT 120

AAATCAAGGA GGAGCCAAAG GGGTGTGTAT AAACTGCCTG GCTAGAAGGG TGGGGGTGTT 180

TCCAGAGAGG CTTCAATGCC ATGAGTCAGC ACAGGAGAAA CACATGCACA GAAACACACA 240

CATGCAGTGC TAGTTTCTAT ATATCAAGCA GACCAGATGT TTTCTAGAGC CTCCCTTTGA 300

GACCTGGGCT CCATGCCCAG AAAAGGGCCT CTTATTGGTG TTCCTGTAAC TTGAAAGCAC 360

TTCCAGGAAA AGGGCCAGAA ATGACTTGGA TTTTTATTAT TGAAAAGGAT GTTTATCCAG 420

TGATACTGTC TAAAAGAGGG TTAAAAAATT GTACTTCATT AAATGTTTCC ACCCCCAATC 480

CTACTGCTCA CACAGCCAGA TTTCTGTTCT GGGTTGCAAA TTTCACTTCT CTCTACAACC 540